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Protein

Golgin subfamily A member 6-like protein 9

Gene

GOLGA6L9

Organism
Homo sapiens (Human)
Status
Reviewed-Annotation score: -Experimental evidence at transcript leveli

Names & Taxonomyi

Protein namesi
Recommended name:
Golgin subfamily A member 6-like protein 9Curated
Gene namesi
Name:GOLGA6L9Imported
Synonyms:GOLGA6L20Imported
OrganismiHomo sapiens (Human)
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
Proteomesi
  • UP000005640 Componenti: Chromosome 15

Organism-specific databases

EuPathDBiHostDB:ENSG00000197978.9
HGNCiHGNC:37229 GOLGA6L9
neXtProtiNX_A6NEM1

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Pathology & Biotechi

Polymorphism and mutation databases

BioMutaiGOLGA6L9

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00003346751 – 432Golgin subfamily A member 6-like protein 9Add BLAST432

Proteomic databases

PaxDbiA6NEM1
PRIDEiA6NEM1
ProteomicsDBi1056
991
992 [A6NEM1-2]

PTM databases

iPTMnetiA6NEM1
PhosphoSitePlusiA6NEM1

Expressioni

Gene expression databases

BgeeiENSG00000197978 Expressed in 86 organ(s), highest expression level in ectocervix

Interactioni

Protein-protein interaction databases

IntActiA6NEM1, 217 interactors
STRINGi9606.ENSP00000300515

Structurei

3D structure databases

ProteinModelPortaliA6NEM1
SMRiA6NEM1
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Coiled coil

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Coiled coili157 – 354Sequence analysisAdd BLAST198

Compositional bias

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Compositional biasi198 – 364Glu-richPROSITE-ProRule annotationAdd BLAST167

Sequence similaritiesi

Belongs to the GOLGA6 family.Curated

Keywords - Domaini

Coiled coil

Phylogenomic databases

eggNOGiKOG4725 Eukaryota
ENOG410ZIE4 LUCA
GeneTreeiENSGT00910000144587
HOGENOMiHOG000218631
HOVERGENiHBG107944
InParanoidiA6NEM1
OMAiAGPSKME
OrthoDBiEOG091G0DDT
TreeFamiTF316990

Family and domain databases

InterProiView protein in InterPro
IPR026737 GOLGA6L
IPR024858 Golgin_A
PANTHERiPTHR23143 PTHR23143, 2 hits
PfamiView protein in Pfam
PF15070 GOLGA2L5, 1 hit

Sequences (2)i

Sequence statusi: Complete.

This entry describes 2 isoformsi produced by alternative splicing. AlignAdd to basket
Isoform 1 (identifier: A6NEM1-1) [UniParc]FASTAAdd to basket

This isoform has been chosen as the 'canonical' sequence. All positional information in this entry refers to it. This is also the sequence that appears in the downloadable versions of the entry.

« Hide
        10         20         30         40         50
MWPQPRLPPH PAMSEKTQQG KLAAAKKKLK AYWQRKSPGI PAGANRKKKI
60 70 80 90 100
NGSSPDTFTS GGYHSPGDSA TGIYGEGRAS STTLQDLESQ YQELAVALDS
110 120 130 140 150
SSAIISQLTE NINSLVRTSK EEKKHEIHLV QKLGRSLFKL KNQTAEPLAP
160 170 180 190 200
QPPAGPSKME QLQDETNHLR KELESVGRQL QAEVENNQML SLLNRRQEER
210 220 230 240 250
LREQEERLRE QEERLCEQEE RLCEQEERLR EQEERLCEQE KLPGQERLLE
260 270 280 290 300
EVEKLLEQER RQEEQERLLE RERLLDEVEE LLEQERLRQQ DERLWQQETL
310 320 330 340 350
RELERLRELE RMLELGWEAL YEQRAEPRSG FEELNNENKS TLQLEQQVKE
360 370 380 390 400
LEKSGGAEEP RGSESAAAAR PVAGAPVPQG AWMCGQAGWT PQEHPGLSGE
410 420 430
AVGTGEAAGG AGEAACHSFR AAENRELNIT II
Length:432
Mass (Da):49,193
Last modified:April 29, 2015 - v4
Checksum:i708C3605EE12530F
GO
Isoform 2 (identifier: A6NEM1-2) [UniParc]FASTAAdd to basket

The sequence of this isoform differs from the canonical sequence as follows:
     1-158: Missing.

Note: No experimental confirmation available.
Show »
Length:274
Mass (Da):32,082
Checksum:iC0C1ADB0F3FCB041
GO

Alternative sequence

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Alternative sequenceiVSP_0337541 – 158Missing in isoform 2. 1 PublicationAdd BLAST158

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC243919 Genomic DNA No translation available.
BC041854 mRNA Translation: AAH41854.1
CCDSiCCDS45326.1 [A6NEM1-1]
RefSeqiNP_001278349.1, NM_001291420.1 [A6NEM1-2]
NP_937824.3, NM_198181.3 [A6NEM1-1]
UniGeneiHs.498322

Genome annotation databases

EnsembliENST00000618348; ENSP00000481078; ENSG00000197978 [A6NEM1-1]
ENST00000620574; ENSP00000479589; ENSG00000274320
GeneIDi440295
KEGGihsa:440295
UCSCiuc032clr.2 human
uc032cxp.2 human [A6NEM1-1]

Keywords - Coding sequence diversityi

Alternative splicing

Similar proteinsi

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC243919 Genomic DNA No translation available.
BC041854 mRNA Translation: AAH41854.1
CCDSiCCDS45326.1 [A6NEM1-1]
RefSeqiNP_001278349.1, NM_001291420.1 [A6NEM1-2]
NP_937824.3, NM_198181.3 [A6NEM1-1]
UniGeneiHs.498322

3D structure databases

ProteinModelPortaliA6NEM1
SMRiA6NEM1
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

IntActiA6NEM1, 217 interactors
STRINGi9606.ENSP00000300515

PTM databases

iPTMnetiA6NEM1
PhosphoSitePlusiA6NEM1

Polymorphism and mutation databases

BioMutaiGOLGA6L9

Proteomic databases

PaxDbiA6NEM1
PRIDEiA6NEM1
ProteomicsDBi1056
991
992 [A6NEM1-2]

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENST00000618348; ENSP00000481078; ENSG00000197978 [A6NEM1-1]
ENST00000620574; ENSP00000479589; ENSG00000274320
GeneIDi440295
KEGGihsa:440295
UCSCiuc032clr.2 human
uc032cxp.2 human [A6NEM1-1]

Organism-specific databases

CTDi440295
EuPathDBiHostDB:ENSG00000197978.9
GeneCardsiGOLGA6L9
HGNCiHGNC:37229 GOLGA6L9
neXtProtiNX_A6NEM1
GenAtlasiSearch...

Phylogenomic databases

eggNOGiKOG4725 Eukaryota
ENOG410ZIE4 LUCA
GeneTreeiENSGT00910000144587
HOGENOMiHOG000218631
HOVERGENiHBG107944
InParanoidiA6NEM1
OMAiAGPSKME
OrthoDBiEOG091G0DDT
TreeFamiTF316990

Miscellaneous databases

ChiTaRSiGOLGA6L9 human
GenomeRNAii440295
PROiPR:A6NEM1

Gene expression databases

BgeeiENSG00000197978 Expressed in 86 organ(s), highest expression level in ectocervix

Family and domain databases

InterProiView protein in InterPro
IPR026737 GOLGA6L
IPR024858 Golgin_A
PANTHERiPTHR23143 PTHR23143, 2 hits
PfamiView protein in Pfam
PF15070 GOLGA2L5, 1 hit
ProtoNetiSearch...

Entry informationi

Entry nameiGG6L9_HUMAN
AccessioniPrimary (citable) accession number: A6NEM1
Secondary accession number(s): A0A087WXJ1
, A6NFL8, H0YK89, Q8IVV3
Entry historyiIntegrated into UniProtKB/Swiss-Prot: May 20, 2008
Last sequence update: April 29, 2015
Last modified: November 7, 2018
This is version 83 of the entry and version 4 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families
  2. Human chromosome 15
    Human chromosome 15: entries, gene names and cross-references to MIM
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Main funding by: National Institutes of Health

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