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UniProtKB - A6NE52 (WDR97_HUMAN)

Entry version 107 (29 Sep 2021)
Sequence version 2 (20 May 2008)
Previous versions | rss
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Protein

WD repeat-containing protein 97

Gene

WDR97

Organism
Homo sapiens (Human)
Status
Reviewed-Annotation score:

Annotation score:3 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>-Experimental evidence at transcript leveli <p>This indicates the type of evidence that supports the existence of the protein. Note that the 'protein existence' evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

Enzyme and pathway databases

Pathway Commons web resource for biological pathway data

More...PathwayCommonsi		A6NE52

SignaLink: a signaling pathway resource with multi-layered regulatory networks

More...SignaLinki		A6NE52

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Recommended name:
WD repeat-containing protein 97Imported
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: 'Name', 'Synonyms', 'Ordered locus names' and 'ORF names'.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:WDR97Imported
Synonyms:KIAA1875
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiHomo sapiens (Human)
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the 'taxonomic identifier' or 'taxid'.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri9606 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Mammalia › Eutheria › Euarchontoglires › Primates › Haplorrhini › Catarrhini › Hominidae › Homo
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000005640 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes_manual">proteome</a> can consist of several components.<br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome 8

Organism-specific databases

Human Gene Nomenclature Database

More...HGNCi		HGNC:26959, WDR97

neXtProt; the human protein knowledge platform

More...neXtProti		NX_A6NE52

Eukaryotic Pathogen, Vector and Host Database Resources

More...VEuPathDBi		HostDB:ENSG00000179698

<p>This section provides information on the disease(s) and phenotype(s) associated with a protein.<p><a href='/help/pathology_and_biotech_section' target='_top'>More...</a></p>Pathology & Biotechi

Organism-specific databases

Open Targets

More...OpenTargetsi		ENSG00000179698

Miscellaneous databases

Pharos NIH Druggable Genome Knowledgebase

More...Pharosi		A6NE52, Tdark

Genetic variation databases

BioMuta curated single-nucleotide variation and disease association database

More...BioMutai		WDR97

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'PTM / Processing' section describes the extent of a polypeptide chain in the mature protein following processing or proteolytic cleavage.<p><a href='/help/chain' target='_top'>More...</a></p>ChainiPRO_00003329941 – 1622WD repeat-containing protein 97Add BLAST1622

Proteomic databases

MassIVE - Mass Spectrometry Interactive Virtual Environment

More...MassIVEi		A6NE52

PaxDb, a database of protein abundance averages across all three domains of life

More...PaxDbi		A6NE52

PeptideAtlas

More...PeptideAtlasi		A6NE52

PRoteomics IDEntifications database

More...PRIDEi		A6NE52

ProteomicsDB: a multi-organism proteome resource

More...ProteomicsDBi		959 [A6NE52-1]
960 [A6NE52-2]

PTM databases

iPTMnet integrated resource for PTMs in systems biology context

More...iPTMneti		A6NE52

Comprehensive resource for the study of protein post-translational modifications (PTMs) in human, mouse and rat.

More...PhosphoSitePlusi		A6NE52

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

Gene expression databases

Bgee dataBase for Gene Expression Evolution

More...Bgeei		ENSG00000179698, Expressed in right testis and 106 other tissues

ExpressionAtlas, Differential and Baseline Expression

More...ExpressionAtlasi		A6NE52, baseline and differential

Genevisible search portal to normalized and curated expression data from Genevestigator

More...Genevisiblei		A6NE52, HS

Organism-specific databases

Human Protein Atlas

More...HPAi		ENSG00000179698, Group enriched (brain, testis)

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

Protein-protein interaction databases

Protein interaction database and analysis system

More...IntActi		A6NE52, 1 interactor

STRING: functional protein association networks

More...STRINGi		9606.ENSP00000320648

Miscellaneous databases

RNAct, Protein-RNA interaction predictions for model organisms.

More...RNActi		A6NE52, protein

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

3D structure databases

SWISS-MODEL Repository - a database of annotated 3D protein structure models

More...SMRi		A6NE52

Database of comparative protein structure models

More...ModBasei		Search...

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Family and Domains' section indicates the positions and types of repeated sequence motifs or repeated domains within the protein.<p><a href='/help/repeat' target='_top'>More...</a></p>Repeati187 – 233WD 1Add BLAST47
Repeati290 – 329WD 2Add BLAST40
Repeati331 – 370WD 3Add BLAST40
Repeati552 – 592WD 4Add BLAST41
Repeati594 – 633WD 5Add BLAST40
Repeati687 – 726WD 6Add BLAST40

Region

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Family and Domains' section describes a region of interest that cannot be described in other subsections.<p><a href='/help/region' target='_top'>More...</a></p>Regioni1090 – 1112DisorderedSequence analysisAdd BLAST23
Regioni1453 – 1472DisorderedSequence analysisAdd BLAST20

Coiled coil

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Family and domains' section denotes the positions of regions of coiled coil within the protein.<p><a href='/help/coiled' target='_top'>More...</a></p>Coiled coili1094 – 1118Sequence analysisAdd BLAST25

Compositional bias

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Family and Domains' section describes the position of regions of compositional bias within the protein and the particular type of amino acids that are over-represented within those regions.<p><a href='/help/compbias' target='_top'>More...</a></p>Compositional biasi1098 – 1112Acidic residuesSequence analysisAdd BLAST15

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywords - Domaini

Coiled coil, Repeat, WD repeat

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

More...eggNOGi		KOG0321, Eukaryota

Ensembl GeneTree

More...GeneTreei		ENSGT00940000164199

The HOGENOM Database of Homologous Genes from Fully Sequenced Organisms

More...HOGENOMi		CLU_244603_0_0_1

InParanoid: Eukaryotic Ortholog Groups

More...InParanoidi		A6NE52

Identification of Orthologs from Complete Genome Data

More...OMAi		WKVPDMV

Database of Orthologous Groups

More...OrthoDBi		313028at2759

Database for complete collections of gene phylogenies

More...PhylomeDBi		A6NE52

Family and domain databases

Gene3D Structural and Functional Annotation of Protein Families

More...Gene3Di		2.130.10.10, 1 hit

Integrated resource of protein families, domains and functional sites

More...InterProi		View protein in InterPro
IPR015943, WD40/YVTN_repeat-like_dom_sf
IPR001680, WD40_repeat
IPR019775, WD40_repeat_CS
IPR036322, WD40_repeat_dom_sf

Pfam protein domain database

More...Pfami		View protein in Pfam
PF00400, WD40, 2 hits

Simple Modular Architecture Research Tool; a protein domain database

More...SMARTi		View protein in SMART
SM00320, WD40, 6 hits

Superfamily database of structural and functional annotation

More...SUPFAMi		SSF50978, SSF50978, 1 hit

PROSITE; a protein domain and family database

More...PROSITEi		View protein in PROSITE
PS00678, WD_REPEATS_1, 2 hits
PS50082, WD_REPEATS_2, 2 hits
PS50294, WD_REPEATS_REGION, 1 hit

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence_length">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequences (2+)i

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences_section">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

This entry describes 2 <p>This subsection of the 'Sequence' section lists the alternative protein sequences (isoforms) that can be generated from the same gene by a single or by the combination of up to four biological events (alternative promoter usage, alternative splicing, alternative initiation and ribosomal frameshifting). Additionally, this section gives relevant information on each alternative protein isoform.<p><a href='/help/alternative_products' target='_top'>More...</a></p> isoformsi produced by alternative splicing. AlignAdd to basket

This entry has 2 described isoforms and 1 potential isoform that is computationally mapped.Show allAlign All

Isoform 1 (identifier: A6NE52-1) [UniParc]FASTAAdd to basket

This isoform has been chosen as the <div> <p><b>What is the canonical sequence?</b><p><a href='/help/canonical_and_isoforms' target='_top'>More...</a></p>canonicali sequence. All positional information in this entry refers to it. This is also the sequence that appears in the downloadable versions of the entry.

« Hide
        10         20         30         40         50
MEAEVWEAEG YNLVLDSDLY DADGYDVPDP GLLTEKNELT FTEPSQVLPF 
        60         70         80         90        100
LTSSQQWQSL TPRARARRLW LLLRTSLHEV VEKEKRAELR AARLTHGLEP 
       110        120        130        140        150
LRRLEVAAGL RSVAQDPVGG RFVVLDGAGR LHLHKEDGWA QETLLAPVRL 
       160        170        180        190        200
TGLVTVLGPL GAVGRFVGWG PAGLAILRPN LSLLWLSEQG VGRAPGWAPT 
       210        220        230        240        250
CCLPVPDLRL LLVAEMNSSL ALWQFRSGGR RLVLRGSALH PPPSPTGRLM 
       260        270        280        290        300
RLAVAPVPPH HVLRCFAAYG SAVLTFDLHA WTLVDVRRDL HKTTISDLAY 
       310        320        330        340        350
CEEVEAMVTA SRDSTVKVWE ADWQIRMVFV GHTGPVTAMT VLPNTTLVLS 
       360        370        380        390        400
ASQDGTLRTW DLQAAAQVGE VALGFWGQDK LSRRVGRLLA PVRPGWPVLS 
       410        420        430        440        450
LCASSMQLWR VRELYSPLAQ LPAKVLHVQV APALPAPAHQ SLPTRLVCAC 
       460        470        480        490        500
ADGSVYLLSA ATGRIVSSLL LEPEDCAAAV AYCLPREALW LLTRAGHLVR 
       510        520        530        540        550
ANAARCPMSV LHRVCPPPPP APQPCCLHLY SHLTDLEGAF SSWEIVRQHW 
       560        570        580        590        600
GELRCSSVAC AWKNKNRYLP VVGHTDGTLS VLEWLSSKTV FQTEAHSPGP 
       610        620        630        640        650
VVAIASTWNS IVSSGGDLTV KMWRVFPYAE ESLSLLRTFS CCYPAVALCA 
       660        670        680        690        700
LGRRVTAGFE DPDSATYGLV QFGLGDSPRL DHRPQDDPTD HITGLCCCPT 
       710        720        730        740        750
LKLYACSSLD CTVRIWTAEN RLLRLLQLNG APQALAFCSN SGDLVLALGS 
       760        770        780        790        800
RLCLVSHRLY LPTSYLVKKM CRKAPDVVDD PPLPLMSQES LTSAQLQRLT 
       810        820        830        840        850
NLHGAASLSE ALSLIHRRRA TSQHLVPKED LDAIVARDRD LQQLRLGLVV 
       860        870        880        890        900
PAAQPPPSWQ QRQEGFDNYL RLIYGSGLLG MQSGRGSQQW SAGTLRVERE 
       910        920        930        940        950
TRDVCAVPQA AHCLARAEVS TAAQTVPTAL SPQDLGALGQ HFSQSPRVTV 
       960        970        980        990       1000
PIPPTHRRVH SKASQLLARS SLSHYLGISL DLQLQLEQLR GRTTMALDLP 
      1010       1020       1030       1040       1050
SSHLQCRIPL LPKRWDKEPL SSLRGFFPAT VQPHKHCLRP ICFPGYVPNS 
      1060       1070       1080       1090       1100
AVLQQMWLNA EPGASQDALW LWRPRPSQTQ WQRKLLQWMG EKPGEEGEED 
      1110       1120       1130       1140       1150
KKEEEEEKED EELDWALASL SPHSNQQLDS WELEDQSAVD WTQEPRRRSC 
      1160       1170       1180       1190       1200
KVARTHPHPW HRHGSLLLDE HYGHLPKFLH FFIYQTWFKK LFPIFSLQAY 
      1210       1220       1230       1240       1250
PEAGTIEGLA SLLVALLEKT TWVDRVHILQ VLLRLLPNMS SDLQGQLQGL 
      1260       1270       1280       1290       1300
LVHLLNLDQP PSLQDQTQKK FVILALQLLL ACSLESRDVV LELMSYFLYS 
      1310       1320       1330       1340       1350
PVHCRPELKK LLHGLGLQDP EGFLFKEMMT WVQGPDLDSK AGLRTCCHQK 
      1360       1370       1380       1390       1400
LEDMIQELQE TPSQTSVVSG APTRASVIPS GTSWSASGIF GRLSQVSEVP 
      1410       1420       1430       1440       1450
LMVVSPAEPH SLAPELQAQR MLAPKRSWGT PQLRLRVLSE TLKSFCLEPE 
      1460       1470       1480       1490       1500
ARLHPAGPAQ LPGEPPPLEE TDWSHSQLLD LGPIDALNFF CEQLRAQQRS 
      1510       1520       1530       1540       1550
SLQEKAAHPH PPEPYTVAPV PDMVVPPPRE HWYHPILRLQ EAKPQRSARS 
      1560       1570       1580       1590       1600
AMRLRGPMRS RLCAGRTLDG PIRTLKLPLP RVEPQPFPLD WPMPPRPLPP 
      1610       1620 
RLLQPALQRY FLPADADPDT YS
Length:1,622
Mass (Da):180,307
Last modified:May 20, 2008 - v2
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:i3991010D04BFD01A
GO
Isoform 2 (identifier: A6NE52-2) [UniParc]FASTAAdd to basket

The sequence of this isoform differs from the canonical sequence as follows:
     809-837: SEALSLIHRRRATSQHLVPKEDLDAIVAR → RSHGGLLSPPGGPPFPLWVGAWRCGALWS
     838-1622: Missing.

Show »
Length:837
Mass (Da):91,360
Checksum:i4AB02FFBFA80A027
GO

<p>In eukaryotic reference proteomes, unreviewed entries that are likely to belong to the same gene are computationally mapped, based on gene identifiers from Ensembl, EnsemblGenomes and model organism databases.<p><a href='/help/gene_centric_isoform_mapping' target='_top'>More...</a></p>Computationally mapped potential isoform sequencesi

There is 1 potential isoform mapped to this entry.BLASTAlignShow allAdd to basket
EntryEntry nameProtein names
Gene namesLengthAnnotation
E9PKB8E9PKB8_HUMAN
WD repeat-containing protein 97
WDR97
837Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>

<p>This subsection of the 'Sequence' section reports difference(s) between the protein sequence shown in the UniProtKB entry and other available protein sequences derived from the same gene.<p><a href='/help/sequence_caution' target='_top'>More...</a></p>Sequence cautioni

The sequence BAB47504 differs from that shown. Reason: Erroneous translation. Wrong choice of CDS.Curated

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Sequence' section reports difference(s) between the canonical sequence (displayed by default in the entry) and the different sequence submissions merged in the entry. These various submissions may originate from different sequencing projects, different types of experiments, or different biological samples. Sequence conflicts are usually of unknown origin.<p><a href='/help/conflict' target='_top'>More...</a></p>Sequence conflicti430V → L in BAB47504 (PubMed:11347906).Curated1

Natural variant

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Sequence' section describes natural variant(s) of the protein sequence.<p><a href='/help/variant' target='_top'>More...</a></p>Natural variantiVAR_043029149R → G1 PublicationCorresponds to variant dbSNP:rs4977196Ensembl.1
Natural variantiVAR_043030427H → Q. Corresponds to variant dbSNP:rs34324679Ensembl.1
Natural variantiVAR_043031537E → G1 PublicationCorresponds to variant dbSNP:rs13250446Ensembl.1

Alternative sequence

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Sequence' section describes the sequence of naturally occurring alternative protein isoform(s). The changes in the amino acid sequence may be due to alternative splicing, alternative promoter usage, alternative initiation, or ribosomal frameshifting.<p><a href='/help/var_seq' target='_top'>More...</a></p>Alternative sequenceiVSP_033425809 – 837SEALS…AIVAR → RSHGGLLSPPGGPPFPLWVG AWRCGALWS in isoform 2. 1 PublicationAdd BLAST29
Alternative sequenceiVSP_033426838 – 1622Missing in isoform 2. 1 PublicationAdd BLAST785

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...EMBLi

GenBank nucleotide sequence database

More...GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...DDBJi
Links Updated
AB058778 mRNA Translation: BAB47504.1 Sequence problems.
AC104592 Genomic DNA No translation available.

The Consensus CDS (CCDS) project

More...CCDSi		CCDS83334.1 [A6NE52-1]

NCBI Reference Sequences

More...RefSeqi		NP_001303238.1, NM_001316309.1 [A6NE52-1]

Genome annotation databases

Ensembl eukaryotic genome annotation project

More...Ensembli		ENST00000323662; ENSP00000320648; ENSG00000179698 [A6NE52-1]

Database of genes from NCBI RefSeq genomes

More...GeneIDi		340390

KEGG: Kyoto Encyclopedia of Genes and Genomes

More...KEGGi		hsa:340390

UCSC genome browser

More...UCSCi		uc064riy.1, human [A6NE52-1]

Keywords - Coding sequence diversityi

Alternative splicing

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AB058778 mRNA Translation: BAB47504.1 Sequence problems.
AC104592 Genomic DNA No translation available.
CCDSiCCDS83334.1 [A6NE52-1]
RefSeqiNP_001303238.1, NM_001316309.1 [A6NE52-1]

3D structure databases

SMRiA6NE52
ModBaseiSearch...

Protein-protein interaction databases

IntActiA6NE52, 1 interactor
STRINGi9606.ENSP00000320648

PTM databases

iPTMnetiA6NE52
PhosphoSitePlusiA6NE52

Genetic variation databases

BioMutaiWDR97

Proteomic databases

MassIVEiA6NE52
PaxDbiA6NE52
PeptideAtlasiA6NE52
PRIDEiA6NE52
ProteomicsDBi959 [A6NE52-1]
960 [A6NE52-2]

Protocols and materials databases

Antibodypedia a portal for validated antibodies

More...Antibodypediai		71324, 5 antibodies

Genome annotation databases

EnsembliENST00000323662; ENSP00000320648; ENSG00000179698 [A6NE52-1]
GeneIDi340390
KEGGihsa:340390
UCSCiuc064riy.1, human [A6NE52-1]

Organism-specific databases

Comparative Toxicogenomics Database

More...CTDi		340390

GeneCards: human genes, protein and diseases

More...GeneCardsi		WDR97
HGNCiHGNC:26959, WDR97
HPAiENSG00000179698, Group enriched (brain, testis)
neXtProtiNX_A6NE52
OpenTargetsiENSG00000179698
VEuPathDBiHostDB:ENSG00000179698

Human Unidentified Gene-Encoded large proteins database

More...HUGEi		Search...

GenAtlas: human gene database

More...GenAtlasi		Search...

Phylogenomic databases

eggNOGiKOG0321, Eukaryota
GeneTreeiENSGT00940000164199
HOGENOMiCLU_244603_0_0_1
InParanoidiA6NE52
OMAiWKVPDMV
OrthoDBi313028at2759
PhylomeDBiA6NE52

Enzyme and pathway databases

PathwayCommonsiA6NE52
SignaLinkiA6NE52

Miscellaneous databases

BioGRID ORCS database of CRISPR phenotype screens

More...BioGRID-ORCSi		340390, 1 hit in 115 CRISPR screens

Database of phenotypes from RNA interference screens in Drosophila and Homo sapiens

More...GenomeRNAii		340390
PharosiA6NE52, Tdark

Protein Ontology

More...PROi		PR:A6NE52
RNActiA6NE52, protein

Gene expression databases

BgeeiENSG00000179698, Expressed in right testis and 106 other tissues
ExpressionAtlasiA6NE52, baseline and differential
GenevisibleiA6NE52, HS

Family and domain databases

Gene3Di2.130.10.10, 1 hit
InterProiView protein in InterPro
IPR015943, WD40/YVTN_repeat-like_dom_sf
IPR001680, WD40_repeat
IPR019775, WD40_repeat_CS
IPR036322, WD40_repeat_dom_sf
PfamiView protein in Pfam
PF00400, WD40, 2 hits
SMARTiView protein in SMART
SM00320, WD40, 6 hits
SUPFAMiSSF50978, SSF50978, 1 hit
PROSITEiView protein in PROSITE
PS00678, WD_REPEATS_1, 2 hits
PS50082, WD_REPEATS_2, 2 hits
PS50294, WD_REPEATS_REGION, 1 hit

MobiDB: a database of protein disorder and mobility annotations

More...MobiDBi		Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the 'Entry information' section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiWDR97_HUMAN
<p>This subsection of the 'Entry information' section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called 'Primary (citable) accession number'.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: A6NE52
Secondary accession number(s): Q96JF2
<p>This subsection of the 'Entry information' section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification ('Last modified'). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/Swiss-Prot: May 20, 2008
Last sequence update: May 20, 2008
Last modified: September 29, 2021
This is version 107 of the entry and version 2 of the sequence. See complete history.
<p>This subsection of the 'Entry information' section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

<p>This section contains any relevant information that doesn't fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Reference proteome

Documents

  1. Human chromosome 8
    Human chromosome 8: entries, gene names and cross-references to MIM
  2. Human entries with genetic variants
    List of human entries with genetic variants
  3. Human variants curated from literature reports
    Index of human variants curated from literature reports
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