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Entry version 69 (16 Jan 2019)
Sequence version 3 (10 Feb 2009)
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Protein

Protein FAM186A

Gene

FAM186A

Organism
Homo sapiens (Human)
Status
Reviewed-Annotation score:

Annotation score:2 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Experimental evidence at transcript leveli <p>This indicates the type of evidence that supports the existence of the protein. Note that the ‘protein existence’ evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Recommended name:
Protein FAM186A
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: ‘Name’, ‘Synonyms’, ‘Ordered locus names’ and ‘ORF names’.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:FAM186A
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiHomo sapiens (Human)
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the ‘taxonomic identifier’ or ‘taxid’.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri9606 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000005640 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes_manual">proteome</a> can consist of several components. <br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome 12

Organism-specific databases

Eukaryotic Pathogen Database Resources

More...
EuPathDBi
HostDB:ENSG00000185958.9

Human Gene Nomenclature Database

More...
HGNCi
HGNC:26980 FAM186A

neXtProt; the human protein knowledge platform

More...
neXtProti
NX_A6NE01

<p>This section provides information on the disease(s) and phenotype(s) associated with a protein.<p><a href='/help/pathology_and_biotech_section' target='_top'>More...</a></p>Pathology & Biotechi

Organism-specific databases

DisGeNET

More...
DisGeNETi
121006

Open Targets

More...
OpenTargetsi
ENSG00000185958

The Pharmacogenetics and Pharmacogenomics Knowledge Base

More...
PharmGKBi
PA164719869

Polymorphism and mutation databases

BioMuta curated single-nucleotide variation and disease association database

More...
BioMutai
FAM186A

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘PTM / Processing’ section describes the extent of a polypeptide chain in the mature protein following processing.<p><a href='/help/chain' target='_top'>More...</a></p>ChainiPRO_00003322011 – 2351Protein FAM186AAdd BLAST2351

Proteomic databases

Encyclopedia of Proteome Dynamics

More...
EPDi
A6NE01

PaxDb, a database of protein abundance averages across all three domains of life

More...
PaxDbi
A6NE01

PRoteomics IDEntifications database

More...
PRIDEi
A6NE01

ProteomicsDB human proteome resource

More...
ProteomicsDBi
951

PTM databases

iPTMnet integrated resource for PTMs in systems biology context

More...
iPTMneti
A6NE01

Comprehensive resource for the study of protein post-translational modifications (PTMs) in human, mouse and rat.

More...
PhosphoSitePlusi
A6NE01

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

Gene expression databases

Bgee dataBase for Gene Expression Evolution

More...
Bgeei
ENSG00000185958 Expressed in 68 organ(s), highest expression level in right testis

ExpressionAtlas, Differential and Baseline Expression

More...
ExpressionAtlasi
A6NE01 baseline and differential

Genevisible search portal to normalized and curated expression data from Genevestigator

More...
Genevisiblei
A6NE01 HS

Organism-specific databases

Human Protein Atlas

More...
HPAi
HPA047128

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

Protein-protein interaction databases

The Biological General Repository for Interaction Datasets (BioGrid)

More...
BioGridi
125703, 1 interactor

Protein interaction database and analysis system

More...
IntActi
A6NE01, 1 interactor

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

3D structure databases

Protein Model Portal of the PSI-Nature Structural Biology Knowledgebase

More...
ProteinModelPortali
A6NE01

SWISS-MODEL Repository - a database of annotated 3D protein structure models

More...
SMRi
A6NE01

Database of comparative protein structure models

More...
ModBasei
Search...

MobiDB: a database of protein disorder and mobility annotations

More...
MobiDBi
Search...

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Coiled coil

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Family and domains’ section denotes the positions of regions of coiled coil within the protein.<p><a href='/help/coiled' target='_top'>More...</a></p>Coiled coili296 – 340Sequence analysisAdd BLAST45
Coiled coili812 – 860Sequence analysisAdd BLAST49

Compositional bias

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Family and Domains’ section describes the position of regions of compositional bias within the protein and the particular amino acids that are over-represented within those regions.<p><a href='/help/compbias' target='_top'>More...</a></p>Compositional biasi913 – 916Poly-Glu4
Compositional biasi1814 – 1943Pro-richAdd BLAST130

<p>This subsection of the ‘Family and domains’ section provides information about the sequence similarity with other proteins.<p><a href='/help/sequence_similarities' target='_top'>More...</a></p>Sequence similaritiesi

Belongs to the FAM186 family.Curated

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywords - Domaini

Coiled coil

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

More...
eggNOGi
ENOG410J3XI Eukaryota
ENOG4111YPH LUCA

Ensembl GeneTree

More...
GeneTreei
ENSGT00940000163376

The HOGENOM Database of Homologous Genes from Fully Sequenced Organisms

More...
HOGENOMi
HOG000112459

InParanoid: Eukaryotic Ortholog Groups

More...
InParanoidi
A6NE01

Identification of Orthologs from Complete Genome Data

More...
OMAi
FTTKKFQ

Database of Orthologous Groups

More...
OrthoDBi
45971at2759

Database for complete collections of gene phylogenies

More...
PhylomeDBi
A6NE01

TreeFam database of animal gene trees

More...
TreeFami
TF338344

Family and domain databases

Integrated resource of protein families, domains and functional sites

More...
InterProi
View protein in InterPro
IPR039332 FAM186A/FAM186B

The PANTHER Classification System

More...
PANTHERi
PTHR33590 PTHR33590, 5 hits

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence_length">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>.<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequence (1+)i

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences_section">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

This entry has 1 described isoform and 3 potential isoforms that are computationally mapped.Show allAlign All

A6NE01-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MFFKMKNEID NDPESEKCIK DSTIMRREPQ NILSPLMLPN LEIPFSVKDI
60 70 80 90 100
ISRIERAQLH RAREDIDMQL SEIMNNVHRI MTRYTLVFNS SSERNVSLTE
110 120 130 140 150
HKKKQRTNFL EKMATYAKTI EIREKTLANI LAWLEEWNDV LSEMTLMDVD
160 170 180 190 200
EHHHWIAQME LLPDTLKAIE NNVKILSRFS TSFLDEKKKQ KKKILSRGTL
210 220 230 240 250
WKSWKERVIK RPSTARALRP DQMISDQLAT NTKVSEIQGM LQELIGTTMF
260 270 280 290 300
STLENNAIKY ISSTIVNLST ALSMLNDELK CVNFQSSTVY AHETSEAEKE
310 320 330 340 350
LSLKIIRDLS NENEMLQQKL QDAEEKCEQL IRSKIVIEQL YAKLSTSSTL
360 370 380 390 400
KVLPGPSPQS SRAIIKVGDT EDNMDNILDK ELENIVDEVQ RKETKDSGIK
410 420 430 440 450
WDSTISYTAQ AERTPDLTEL RQQPVASEDI SEDSTKDNVS LKKGDFYQED
460 470 480 490 500
ETDEYQSWKR SHKKATYVYE TSGPNLSDNK SGQKVSEAKP SQYYELQVLK
510 520 530 540 550
KKRKEMKSFS EDKSKSPTEA KRKHLSLTET KSQGGKSGTS MMMLEQFRKV
560 570 580 590 600
KRESPFDKRP TAAEIKVEPT TESLDKEGKG EIRSLVEPLS MIQFDDTAEP
610 620 630 640 650
QKGKIKGKKH HISSGTITSK EEKTEEKEEL TKQVKSHQLV KSLSRVAKET
660 670 680 690 700
SESTRVLESP DGKSEQSNLE EFQEAIMAFL KQKIDNIGKA FDKKTVPKEE
710 720 730 740 750
ELLKRAEAEK LGIIKAKMEE YFQKVAETVT KILRKYKDTK KEEQVGEKPI
760 770 780 790 800
KQKKVVSFMP GLHFQKSPIS AKSESSTLLS YESTDPVINN LIQMILAEIE
810 820 830 840 850
SERDIPTVST VQKDHKEKEK QRQEQYLQEG QEQMSGMSLK QQLLGERNLL
860 870 880 890 900
KEHYEKISEN WEEKKAWLQM KEGKQEQQSQ KQWQEEEMWK EEQKQATPKQ
910 920 930 940 950
AEQEEKQKQR GQEEEELPKS SLQRLEEGTQ KMKTQGLLLE KENGQMRQIQ
960 970 980 990 1000
KEAKHLGPHR RREKGKEKQK PERGLEDLER QIKTKDQMQM KETQPKELEK
1010 1020 1030 1040 1050
MVIQTPMTLS PRWKSVLKDV QRSYEGKEFQ RNLKTLENLP DEKEPISITP
1060 1070 1080 1090 1100
PPSLQYSLPG ALPISGQPLT KCIHLTPQQA QEVGITLTPQ QAQAQGITLT
1110 1120 1130 1140 1150
LQQAQELGIP LTPQQAQALE ILFTPQQAQA LGIPLTPQQT QVQGITLTPQ
1160 1170 1180 1190 1200
QDQAPGISLT TQQAQKLGIP LTPQQAQALG IPLTPQQAQE LGIPLTPQQA
1210 1220 1230 1240 1250
QALRVSLTPQ QAQELGIPLT PQQAQALGIT LTLQQAQQLG IPLTPQQAQA
1260 1270 1280 1290 1300
LGITLTPKQV QELGIPLTPQ QAQALGITLT PKQAQELGIP LNPQQAQTLG
1310 1320 1330 1340 1350
IPLTPKQAQA LGIPFTPQQA QALGIPLTPQ QAQTQEITLT PQQAQALGMP
1360 1370 1380 1390 1400
LTTQQAQELG IPLTPQHAQA LGMPLTTQQA QELGIPLTPQ QAQALGMPLT
1410 1420 1430 1440 1450
TQQAQELGIP LTPQQAQELG IPFTPQQAQA QEITLTPQQA QALGMPLTAQ
1460 1470 1480 1490 1500
QAQELGITLT PQQAQELGIP LTPQQAQALG IPLIPPQAQE LGIPLTPQQA
1510 1520 1530 1540 1550
QALGILLIPP QAQELGIPLT PQQAQALGIP LIPPQAQELG IPLTPQQVQA
1560 1570 1580 1590 1600
LGIPLIPPQA QELEIPLTPQ QAQALGIPLT PQQAQELGIP LTPQQAQELG
1610 1620 1630 1640 1650
IPLTPQQAQA QGIPLTPQQA QALGISLTPQ QAQAQGITLT PQQAQALGVP
1660 1670 1680 1690 1700
ITPVNAWVSA VTLTSEQTHA LESPMNLEQA QEQLLKLGVP LTLDKAHTLG
1710 1720 1730 1740 1750
SPLTLKQVQW SHRPFQKSKA SLPTGQSIIS RLSPSLRLSL ASSAPTAEKS
1760 1770 1780 1790 1800
SIFGVSSTPL QISRVPLNQG PFAPGKPLEM GILSEPGKLG APQTLRSSGQ
1810 1820 1830 1840 1850
TLVYGGQSTS AQFPAPQAPP SPGQLPISRA PPTPGQPFIA GVPPTSGQIP
1860 1870 1880 1890 1900
SLWAPLSPGQ PLVPEASSIP GDLLESGPLT FSEQLQEFQP PATAEQSPYL
1910 1920 1930 1940 1950
QAPSTPGQHL ATWTLPGRAS SLWIPPTSRH PPTLWPSPAP GKPQKSWSPS
1960 1970 1980 1990 2000
VAKKRLAIIS SLKSKSVLIH PSAPDFKVAQ VPFTTKKFQM SEVSDTSEET
2010 2020 2030 2040 2050
QILRDTFAIE SFRTFQSHFT KYRTPVYQTP YTDERALLTL MKPTTSPSSL
2060 2070 2080 2090 2100
TTLLRTSQIS PLEWYQKSRF PPIDKPWILS SVSDTKKPKV MVPPSSPQEL
2110 2120 2130 2140 2150
EEKRYFVDVE AQKKNLILLN QAIKTCGLPS QLHTMARTLI IEILHMDTVQ
2160 2170 2180 2190 2200
LGYLFRKYIA YRLIQHARNN IMKRLKAIQN TGKGYEARNL HMMLSRLDDY
2210 2220 2230 2240 2250
GKKVMQVWTE KQKSLGQKRN QCLKKMIHVF NQLKKIHELN LSQPIPLIIE
2260 2270 2280 2290 2300
EKQIPASTTF VQKPFLKLLM EEDRTSDICK KFRQQEDQTE AIWNVDLSTS
2310 2320 2330 2340 2350
SYPIAEKTSM HSLWAQLGGY PDIPRLLQLE VQSTFRKSLA SLQSRVKKIP

K
Length:2,351
Mass (Da):262,758
Last modified:February 10, 2009 - v3
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:i290E59F3CC9085B4
GO

<p>In eukaryotic reference proteomes, unreviewed entries that are likely to belong to the same gene are computationally mapped, based on gene identifiers from Ensembl, EnsemblGenomes and model organism databases.<p><a href='/help/gene_centric_isoform_mapping' target='_top'>More...</a></p>Computationally mapped potential isoform sequencesi

There are 3 potential isoforms mapped to this entry.BLASTAlignShow allAdd to basket
EntryEntry nameProtein names
Gene namesLengthAnnotation
F5GYN0F5GYN0_HUMAN
Protein FAM186A
FAM186A
2,348Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
F5H8C1F5H8C1_HUMAN
Protein FAM186A
FAM186A
359Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
H0YFA1H0YFA1_HUMAN
Protein FAM186A
FAM186A
73Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Sequence’ section reports difference(s) between the canonical sequence (displayed by default in the entry) and the different sequence submissions merged in the entry. These various submissions may originate from different sequencing projects, different types of experiments, or different biological samples. Sequence conflicts are usually of unknown origin.<p><a href='/help/conflict' target='_top'>More...</a></p>Sequence conflicti165T → M in AL833333 (PubMed:17974005).Curated1
Sequence conflicti463 – 465KKA → TKG in AL833333 (PubMed:17974005).Curated3
Sequence conflicti935Q → R in AL833333 (PubMed:17974005).Curated1

Natural variant

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Sequence’ section describes natural variant(s) of the protein sequence.<p><a href='/help/variant' target='_top'>More...</a></p>Natural variantiVAR_054419187K → Q1 PublicationCorresponds to variant dbSNP:rs12303082Ensembl.1
Natural variantiVAR_0544201204R → G. Corresponds to variant dbSNP:rs10876024Ensembl.1
Natural variantiVAR_0544211233L → P. Corresponds to variant dbSNP:rs10876023Ensembl.1
Natural variantiVAR_0544222166H → Y. Corresponds to variant dbSNP:rs7296291Ensembl.1
Natural variantiVAR_0544232193M → I. Corresponds to variant dbSNP:rs6580742Ensembl.1
Natural variantiVAR_0544242228H → Q1 PublicationCorresponds to variant dbSNP:rs6580741Ensembl.1
Natural variantiVAR_0544252316Q → E. Corresponds to variant dbSNP:rs12809349Ensembl.1

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...
EMBLi

GenBank nucleotide sequence database

More...
GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...
DDBJi
Links Updated
AC090058 Genomic DNA No translation available.
AC140061 Genomic DNA No translation available.
AL833333 mRNA No translation available.
BX099768 mRNA No translation available.

The Consensus CDS (CCDS) project

More...
CCDSi
CCDS44878.1

NCBI Reference Sequences

More...
RefSeqi
NP_001138947.1, NM_001145475.1

UniGene gene-oriented nucleotide sequence clusters

More...
UniGenei
Hs.133187

Genome annotation databases

Ensembl eukaryotic genome annotation project

More...
Ensembli
ENST00000327337; ENSP00000329995; ENSG00000185958

Database of genes from NCBI RefSeq genomes

More...
GeneIDi
121006

KEGG: Kyoto Encyclopedia of Genes and Genomes

More...
KEGGi
hsa:121006

UCSC genome browser

More...
UCSCi
uc001rwl.3 human

Keywords - Coding sequence diversityi

Polymorphism

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC090058 Genomic DNA No translation available.
AC140061 Genomic DNA No translation available.
AL833333 mRNA No translation available.
BX099768 mRNA No translation available.
CCDSiCCDS44878.1
RefSeqiNP_001138947.1, NM_001145475.1
UniGeneiHs.133187

3D structure databases

ProteinModelPortaliA6NE01
SMRiA6NE01
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

BioGridi125703, 1 interactor
IntActiA6NE01, 1 interactor

PTM databases

iPTMnetiA6NE01
PhosphoSitePlusiA6NE01

Polymorphism and mutation databases

BioMutaiFAM186A

Proteomic databases

EPDiA6NE01
PaxDbiA6NE01
PRIDEiA6NE01
ProteomicsDBi951

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENST00000327337; ENSP00000329995; ENSG00000185958
GeneIDi121006
KEGGihsa:121006
UCSCiuc001rwl.3 human

Organism-specific databases

Comparative Toxicogenomics Database

More...
CTDi
121006
DisGeNETi121006
EuPathDBiHostDB:ENSG00000185958.9

GeneCards: human genes, protein and diseases

More...
GeneCardsi
FAM186A

H-Invitational Database, human transcriptome db

More...
H-InvDBi
HIX0010627
HGNCiHGNC:26980 FAM186A
HPAiHPA047128
neXtProtiNX_A6NE01
OpenTargetsiENSG00000185958
PharmGKBiPA164719869

GenAtlas: human gene database

More...
GenAtlasi
Search...

Phylogenomic databases

eggNOGiENOG410J3XI Eukaryota
ENOG4111YPH LUCA
GeneTreeiENSGT00940000163376
HOGENOMiHOG000112459
InParanoidiA6NE01
OMAiFTTKKFQ
OrthoDBi45971at2759
PhylomeDBiA6NE01
TreeFamiTF338344

Miscellaneous databases

Database of phenotypes from RNA interference screens in Drosophila and Homo sapiens

More...
GenomeRNAii
121006

Protein Ontology

More...
PROi
PR:A6NE01

Gene expression databases

BgeeiENSG00000185958 Expressed in 68 organ(s), highest expression level in right testis
ExpressionAtlasiA6NE01 baseline and differential
GenevisibleiA6NE01 HS

Family and domain databases

InterProiView protein in InterPro
IPR039332 FAM186A/FAM186B
PANTHERiPTHR33590 PTHR33590, 5 hits

ProtoNet; Automatic hierarchical classification of proteins

More...
ProtoNeti
Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the ‘Entry information’ section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiF186A_HUMAN
<p>This subsection of the ‘Entry information’ section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called ‘Primary (citable) accession number’.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: A6NE01
<p>This subsection of the ‘Entry information’ section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification (‘Last modified’). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/Swiss-Prot: April 29, 2008
Last sequence update: February 10, 2009
Last modified: January 16, 2019
This is version 69 of the entry and version 3 of the sequence. See complete history.
<p>This subsection of the ‘Entry information’ section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

<p>This section contains any relevant information that doesn’t fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families
  2. Human chromosome 12
    Human chromosome 12: entries, gene names and cross-references to MIM
  3. Human entries with polymorphisms or disease mutations
    List of human entries with polymorphisms or disease mutations
  4. Human polymorphisms and disease mutations
    Index of human polymorphisms and disease mutations
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