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UniProtKB - A6NCJ1 (CS071_HUMAN)

Entry version 65 (16 Jan 2019)
Sequence version 2 (22 Jul 2008)
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Protein

Uncharacterized protein C19orf71

Gene

C19orf71

Organism
Homo sapiens (Human)
Status
Reviewed-Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>-Protein predictedi <p>This indicates the type of evidence that supports the existence of the protein. Note that the ‘protein existence’ evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Recommended name:
Uncharacterized protein C19orf71
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: ‘Name’, ‘Synonyms’, ‘Ordered locus names’ and ‘ORF names’.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:C19orf71
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiHomo sapiens (Human)
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the ‘taxonomic identifier’ or ‘taxid’.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri9606 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Mammalia › Eutheria › Euarchontoglires › Primates › Haplorrhini › Catarrhini › Hominidae › Homo
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000005640 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes_manual">proteome</a> can consist of several components. <br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome 19

Organism-specific databases

Eukaryotic Pathogen Database Resources

More...EuPathDBi		HostDB:ENSG00000183397.5

Human Gene Nomenclature Database

More...HGNCi		HGNC:34496 C19orf71

neXtProt; the human protein knowledge platform

More...neXtProti		NX_A6NCJ1

<p>This section provides information on the disease(s) and phenotype(s) associated with a protein.<p><a href='/help/pathology_and_biotech_section' target='_top'>More...</a></p>Pathology & Biotechi

Organism-specific databases

Open Targets

More...OpenTargetsi		ENSG00000183397

The Pharmacogenetics and Pharmacogenomics Knowledge Base

More...PharmGKBi		PA164716956

Polymorphism and mutation databases

BioMuta curated single-nucleotide variation and disease association database

More...BioMutai		C19orf71

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘PTM / Processing’ section describes the extent of a polypeptide chain in the mature protein following processing.<p><a href='/help/chain' target='_top'>More...</a></p>ChainiPRO_00003321951 – 209Uncharacterized protein C19orf71Add BLAST209

Proteomic databases

jPOST - Japan Proteome Standard Repository/Database

More...jPOSTi		A6NCJ1

PaxDb, a database of protein abundance averages across all three domains of life

More...PaxDbi		A6NCJ1

PRoteomics IDEntifications database

More...PRIDEi		A6NCJ1

ProteomicsDB human proteome resource

More...ProteomicsDBi		839

PTM databases

iPTMnet integrated resource for PTMs in systems biology context

More...iPTMneti		A6NCJ1

Comprehensive resource for the study of protein post-translational modifications (PTMs) in human, mouse and rat.

More...PhosphoSitePlusi		A6NCJ1

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

Gene expression databases

Bgee dataBase for Gene Expression Evolution

More...Bgeei		ENSG00000183397 Expressed in 87 organ(s), highest expression level in right hemisphere of cerebellum

Organism-specific databases

Human Protein Atlas

More...HPAi		HPA048654

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

3D structure databases

Protein Model Portal of the PSI-Nature Structural Biology Knowledgebase

More...ProteinModelPortali		A6NCJ1

Database of comparative protein structure models

More...ModBasei		Search...

MobiDB: a database of protein disorder and mobility annotations

More...MobiDBi		Search...

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

More...eggNOGi		ENOG410IYAQ Eukaryota
ENOG410YWU0 LUCA

Ensembl GeneTree

More...GeneTreei		ENSGT00390000004282

The HOGENOM Database of Homologous Genes from Fully Sequenced Organisms

More...HOGENOMi		HOG000090216

InParanoid: Eukaryotic Ortholog Groups

More...InParanoidi		A6NCJ1

Identification of Orthologs from Complete Genome Data

More...OMAi		EPYCPST

Database of Orthologous Groups

More...OrthoDBi		605453at2759

Database for complete collections of gene phylogenies

More...PhylomeDBi		A6NCJ1

TreeFam database of animal gene trees

More...TreeFami		TF336002

Family and domain databases

Integrated resource of protein families, domains and functional sites

More...InterProi		View protein in InterPro
IPR029203 DUF4531

The PANTHER Classification System

More...PANTHERi		PTHR31254 PTHR31254, 1 hit

Pfam protein domain database

More...Pfami		View protein in Pfam
PF15041 DUF4531, 1 hit

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence_length">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>.<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequencei

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences_section">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

A6NCJ1-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MQTLRQEAAR PCIPSGTLEA SFPAPLYSDD YLSLEGSRWP PAIRQATRWK 
        60         70         80         90        100
YTPMGRDAAG QLWYTGLTNS DAWEAWYNLP RAPASPFREA YNRWHSCYQH 
       110        120        130        140        150
RECSMPSAYT QHLRETAWHD PIVPAQYQAP STRWGSALWK DRPIRGKEYV 
       160        170        180        190        200
LNRNRYGVEP LWRASDYVPS LSAPQRPPGT TQNYREWVLE PYCPSTCQRS 

PPSLTPTPR
Length:209
Mass (Da):24,176
Last modified:July 22, 2008 - v2
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:i2D40E238DBA50289
GO

Natural variant

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Sequence’ section describes natural variant(s) of the protein sequence.<p><a href='/help/variant' target='_top'>More...</a></p>Natural variantiVAR_06125383P → L. Corresponds to variant dbSNP:rs12608919Ensembl.1
Natural variantiVAR_061254137A → V. Corresponds to variant dbSNP:rs6510758Ensembl.1

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...EMBLi

GenBank nucleotide sequence database

More...GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...DDBJi
Links Updated
AC005786 Genomic DNA No translation available.

The Consensus CDS (CCDS) project

More...CCDSi		CCDS45918.1

NCBI Reference Sequences

More...RefSeqi		NP_001129052.1, NM_001135580.1

UniGene gene-oriented nucleotide sequence clusters

More...UniGenei		Hs.664978

Genome annotation databases

Ensembl eukaryotic genome annotation project

More...Ensembli		ENST00000329493; ENSP00000327950; ENSG00000183397

Database of genes from NCBI RefSeq genomes

More...GeneIDi		100128569

KEGG: Kyoto Encyclopedia of Genes and Genomes

More...KEGGi		hsa:100128569

UCSC genome browser

More...UCSCi		uc010xhm.3 human

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywords - Coding sequence diversityi

Polymorphism

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC005786 Genomic DNA No translation available.
CCDSiCCDS45918.1
RefSeqiNP_001129052.1, NM_001135580.1
UniGeneiHs.664978

3D structure databases

ProteinModelPortaliA6NCJ1
ModBaseiSearch...
MobiDBiSearch...

PTM databases

iPTMnetiA6NCJ1
PhosphoSitePlusiA6NCJ1

Polymorphism and mutation databases

BioMutaiC19orf71

Proteomic databases

jPOSTiA6NCJ1
PaxDbiA6NCJ1
PRIDEiA6NCJ1
ProteomicsDBi839

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENST00000329493; ENSP00000327950; ENSG00000183397
GeneIDi100128569
KEGGihsa:100128569
UCSCiuc010xhm.3 human

Organism-specific databases

Comparative Toxicogenomics Database

More...CTDi		100128569
EuPathDBiHostDB:ENSG00000183397.5

GeneCards: human genes, protein and diseases

More...GeneCardsi		C19orf71
HGNCiHGNC:34496 C19orf71
HPAiHPA048654
neXtProtiNX_A6NCJ1
OpenTargetsiENSG00000183397
PharmGKBiPA164716956

GenAtlas: human gene database

More...GenAtlasi		Search...

Phylogenomic databases

eggNOGiENOG410IYAQ Eukaryota
ENOG410YWU0 LUCA
GeneTreeiENSGT00390000004282
HOGENOMiHOG000090216
InParanoidiA6NCJ1
OMAiEPYCPST
OrthoDBi605453at2759
PhylomeDBiA6NCJ1
TreeFamiTF336002

Miscellaneous databases

Database of phenotypes from RNA interference screens in Drosophila and Homo sapiens

More...GenomeRNAii		100128569

Protein Ontology

More...PROi		PR:A6NCJ1

Gene expression databases

BgeeiENSG00000183397 Expressed in 87 organ(s), highest expression level in right hemisphere of cerebellum

Family and domain databases

InterProiView protein in InterPro
IPR029203 DUF4531
PANTHERiPTHR31254 PTHR31254, 1 hit
PfamiView protein in Pfam
PF15041 DUF4531, 1 hit

ProtoNet; Automatic hierarchical classification of proteins

More...ProtoNeti		Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the ‘Entry information’ section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiCS071_HUMAN
<p>This subsection of the ‘Entry information’ section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called ‘Primary (citable) accession number’.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: A6NCJ1
<p>This subsection of the ‘Entry information’ section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification (‘Last modified’). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/Swiss-Prot: April 29, 2008
Last sequence update: July 22, 2008
Last modified: January 16, 2019
This is version 65 of the entry and version 2 of the sequence. See complete history.
<p>This subsection of the ‘Entry information’ section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

<p>This section contains any relevant information that doesn’t fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Human chromosome 19
    Human chromosome 19: entries, gene names and cross-references to MIM
  2. Human entries with polymorphisms or disease mutations
    List of human entries with polymorphisms or disease mutations
  3. Human polymorphisms and disease mutations
    Index of human polymorphisms and disease mutations
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