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Protein

Uncharacterized protein C2orf78

Gene

C2orf78

Organism
Homo sapiens (Human)
Status
Reviewed-Annotation score: -Experimental evidence at transcript leveli

Names & Taxonomyi

Protein namesi
Recommended name:
Uncharacterized protein C2orf78
Gene namesi
Name:C2orf78
OrganismiHomo sapiens (Human)
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
Proteomesi
  • UP000005640 Componenti: Chromosome 2

Organism-specific databases

EuPathDBiHostDB:ENSG00000187833.7
HGNCiHGNC:34349 C2orf78
neXtProtiNX_A6NCI8

Pathology & Biotechi

Organism-specific databases

OpenTargetsiENSG00000187833

Polymorphism and mutation databases

BioMutaiC2orf78

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00003194221 – 922Uncharacterized protein C2orf78Add BLAST922

Proteomic databases

PaxDbiA6NCI8
PRIDEiA6NCI8
ProteomicsDBi838

PTM databases

iPTMnetiA6NCI8
PhosphoSitePlusiA6NCI8

Expressioni

Gene expression databases

BgeeiENSG00000187833 Expressed in 6 organ(s), highest expression level in right testis
CleanExiHS_C2orf78

Structurei

3D structure databases

ProteinModelPortaliA6NCI8
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Coiled coil

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Coiled coili872 – 899Sequence analysisAdd BLAST28

Compositional bias

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Compositional biasi11 – 141Ser-richAdd BLAST131
Compositional biasi546 – 621Lys-richAdd BLAST76

Keywords - Domaini

Coiled coil

Phylogenomic databases

eggNOGiENOG410IVAP Eukaryota
ENOG41115RW LUCA
GeneTreeiENSGT00390000014208
HOGENOMiHOG000060273
HOVERGENiHBG070856
InParanoidiA6NCI8
OMAiYRASAHQ
OrthoDBiEOG091G07UF
PhylomeDBiA6NCI8
TreeFamiTF337929

Family and domain databases

InterProiView protein in InterPro
IPR027898 DUF4629
PfamiView protein in Pfam
PF15442 DUF4629, 1 hit

Sequencei

Sequence statusi: Complete.

A6NCI8-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MHWLASATQT SASIVSSSLL SAVDVSSSLT MSEYFQNTSL PGTANSRQFS
60 70 80 90 100
LPVVSNAAFL TGSISNFSRA SAPAISSAWL QPSASGTSFQ PLMGSAYLYQ
110 120 130 140 150
HSSTTMLSGV TGQSHICTSA ASYPGVFEWD STASTVKKSS SLRDFTVTVI
160 170 180 190 200
DQNTAVSSMS MTAQYYKTSD TNTMVPLYPS LSASLVQGTL TQIPNQQGHN
210 220 230 240 250
LSLPCQIGSQ VYYYNQGTLG PQLSCLQSYG SVSYTGYRAS AHQPEMVMVL
260 270 280 290 300
KEVQPTNVLP PVSTSGMYYS VSSQPITETS VQVMETSLGM DTSLGLQSPS
310 320 330 340 350
QTFCLPQTPE FSKSFSSRNT QTLESNPSPE LGDISITPVQ SPTNLLTLSP
360 370 380 390 400
APSQEKNENE NLDEIKTNLS KPLDVHQILI GNQDPPLLPV EIPDIHPLLA
410 420 430 440 450
CIDPLGQEEQ PGSENANLRN KSLSLEDQGI FENGIESSSD LADITTWVED
460 470 480 490 500
TYLPPIFSSL QDLDQPESPS AKKAKDTSAI KVNQVQEKSC VIKGHSDQVR
510 520 530 540 550
KNKHKASEPI QGAPKAKIQP KNPECLLERE VVVGSATVSN SASVNKAKHS
560 570 580 590 600
SNKPHKAASS RISKTKSHGQ EKTKGNRKNS SKKSEESKQS GKKVKVEEKQ
610 620 630 640 650
TIPNMKRKKN QPELSQKTLK KPRSSLGMHM LESVQVFHAL GKKIDMKTGF
660 670 680 690 700
SSSRTLGSSS NTQNRQPFPA LKPWLDIQHE GKGPEKIQVK AQKLDGSAEK
710 720 730 740 750
ECTSPSHSEL PPPGKVKLIP LPFLTLDQPQ ARHVSRRPNP LASRRPAVAY
760 770 780 790 800
PARPDSTNSA QSNAVNPSRP APTNTSLTGP ATPAQPISAK ATQPSSANPT
810 820 830 840 850
QPTVPQSAAS RPSAYKTSSC SSLQREPVST AVTSLRSLPK PQNQFLIQDF
860 870 880 890 900
SLQPRPWRKP TVPEPVMSTP ITEEQRPERE AMKRKAQQER ENAAKYTSLG
910 920
KVQFFIERER DMEIAEYYGY TI
Length:922
Mass (Da):100,170
Last modified:April 5, 2011 - v3
Checksum:i866A70E766774B03
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AK125975 mRNA No translation available.
AC092653 Genomic DNA No translation available.
CCDSiCCDS46338.1
RefSeqiNP_001073943.1, NM_001080474.1
XP_005264359.1, XM_005264302.3
UniGeneiHs.456833

Genome annotation databases

EnsembliENST00000409561; ENSP00000387124; ENSG00000187833
GeneIDi388960
KEGGihsa:388960
UCSCiuc002sjr.1 human

Similar proteinsi

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AK125975 mRNA No translation available.
AC092653 Genomic DNA No translation available.
CCDSiCCDS46338.1
RefSeqiNP_001073943.1, NM_001080474.1
XP_005264359.1, XM_005264302.3
UniGeneiHs.456833

3D structure databases

ProteinModelPortaliA6NCI8
ModBaseiSearch...
MobiDBiSearch...

PTM databases

iPTMnetiA6NCI8
PhosphoSitePlusiA6NCI8

Polymorphism and mutation databases

BioMutaiC2orf78

Proteomic databases

PaxDbiA6NCI8
PRIDEiA6NCI8
ProteomicsDBi838

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENST00000409561; ENSP00000387124; ENSG00000187833
GeneIDi388960
KEGGihsa:388960
UCSCiuc002sjr.1 human

Organism-specific databases

CTDi388960
EuPathDBiHostDB:ENSG00000187833.7
GeneCardsiC2orf78
HGNCiHGNC:34349 C2orf78
neXtProtiNX_A6NCI8
OpenTargetsiENSG00000187833
GenAtlasiSearch...

Phylogenomic databases

eggNOGiENOG410IVAP Eukaryota
ENOG41115RW LUCA
GeneTreeiENSGT00390000014208
HOGENOMiHOG000060273
HOVERGENiHBG070856
InParanoidiA6NCI8
OMAiYRASAHQ
OrthoDBiEOG091G07UF
PhylomeDBiA6NCI8
TreeFamiTF337929

Miscellaneous databases

GenomeRNAii388960
PROiPR:A6NCI8

Gene expression databases

BgeeiENSG00000187833 Expressed in 6 organ(s), highest expression level in right testis
CleanExiHS_C2orf78

Family and domain databases

InterProiView protein in InterPro
IPR027898 DUF4629
PfamiView protein in Pfam
PF15442 DUF4629, 1 hit
ProtoNetiSearch...

Entry informationi

Entry nameiCB078_HUMAN
AccessioniPrimary (citable) accession number: A6NCI8
Entry historyiIntegrated into UniProtKB/Swiss-Prot: February 26, 2008
Last sequence update: April 5, 2011
Last modified: November 7, 2018
This is version 65 of the entry and version 3 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Human chromosome 2
    Human chromosome 2: entries, gene names and cross-references to MIM
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Main funding by: National Institutes of Health

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