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UniProtKB - A6MFL3 (VKT3_DEMVE)
Protein
Kunitz-type serine protease inhibitor vestiginin-3
Gene
N/A
Organism
Demansia vestigiata (Lesser black whip snake) (Demansia atra)
Status
Functioni
Serine protease inhibitor.
By similaritySites
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Sitei | 41 – 42 | Reactive bond for trypsinBy similarity | 2 |
GO - Molecular functioni
- serine-type endopeptidase inhibitor activity Source: UniProtKB-KW
Keywordsi
Molecular function | Protease inhibitor, Serine protease inhibitor |
Names & Taxonomyi
Protein namesi | Recommended name: Kunitz-type serine protease inhibitor vestiginin-3 |
Organismi | Demansia vestigiata (Lesser black whip snake) (Demansia atra) |
Taxonomic identifieri | 412038 [NCBI] |
Taxonomic lineagei | Eukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Lepidosauria › Squamata › Bifurcata › Unidentata › Episquamata › Toxicofera › Serpentes › Colubroidea › Elapidae › Notechinae › Demansia |
Subcellular locationi
Extracellular region or secreted
- Secreted By similarity
Extracellular region or secreted
- extracellular region Source: UniProtKB-SubCell
Keywords - Cellular componenti
SecretedPTM / Processingi
Molecule processing
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Signal peptidei | 1 – 24 | Sequence analysisAdd BLAST | 24 | |
ChainiPRO_5000254117 | 25 – 83 | Kunitz-type serine protease inhibitor vestiginin-3Add BLAST | 59 |
Amino acid modifications
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Disulfide bondi | 31 ↔ 81 | PROSITE-ProRule annotation | ||
Disulfide bondi | 40 ↔ 64 | PROSITE-ProRule annotation | ||
Disulfide bondi | 56 ↔ 77 | PROSITE-ProRule annotation |
Keywords - PTMi
Disulfide bondExpressioni
Tissue specificityi
Expressed by the venom gland.
Family & Domainsi
Domains and Repeats
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Domaini | 31 – 81 | BPTI/Kunitz inhibitorPROSITE-ProRule annotationAdd BLAST | 51 |
Sequence similaritiesi
Belongs to the venom Kunitz-type family.Curated
Keywords - Domaini
SignalFamily and domain databases
CDDi | cd00109, KU, 1 hit |
Gene3Di | 4.10.410.10, 1 hit |
InterProi | View protein in InterPro IPR002223, Kunitz_BPTI IPR036880, Kunitz_BPTI_sf IPR020901, Prtase_inh_Kunz-CS |
Pfami | View protein in Pfam PF00014, Kunitz_BPTI, 1 hit |
PRINTSi | PR00759, BASICPTASE |
SMARTi | View protein in SMART SM00131, KU, 1 hit |
SUPFAMi | SSF57362, SSF57362, 1 hit |
PROSITEi | View protein in PROSITE PS00280, BPTI_KUNITZ_1, 1 hit PS50279, BPTI_KUNITZ_2, 1 hit |
i Sequence
Sequence statusi: Complete.
: The displayed sequence is further processed into a mature form. Sequence processingi
A6MFL3-1 [UniParc]FASTAAdd to basket
10 20 30 40 50
MSSGGLLLLL GLLTLWAELT PVSSKDLPEI CKLPKEPGPC RSYLLYFYYN
60 70 80
SVEHKCQTFH YGGCEGNENR FHTIEECKST CAE
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | DQ917524 mRNA Translation: ABK63553.1 EU401860 Genomic DNA Translation: ACC77809.1 |
Similar proteinsi
Cross-referencesi
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | DQ917524 mRNA Translation: ABK63553.1 EU401860 Genomic DNA Translation: ACC77809.1 |
3D structure databases
SMRi | A6MFL3 |
ModBasei | Search... |
Family and domain databases
CDDi | cd00109, KU, 1 hit |
Gene3Di | 4.10.410.10, 1 hit |
InterProi | View protein in InterPro IPR002223, Kunitz_BPTI IPR036880, Kunitz_BPTI_sf IPR020901, Prtase_inh_Kunz-CS |
Pfami | View protein in Pfam PF00014, Kunitz_BPTI, 1 hit |
PRINTSi | PR00759, BASICPTASE |
SMARTi | View protein in SMART SM00131, KU, 1 hit |
SUPFAMi | SSF57362, SSF57362, 1 hit |
PROSITEi | View protein in PROSITE PS00280, BPTI_KUNITZ_1, 1 hit PS50279, BPTI_KUNITZ_2, 1 hit |
MobiDBi | Search... |
Entry informationi
Entry namei | VKT3_DEMVE | |
Accessioni | A6MFL3Primary (citable) accession number: A6MFL3 | |
Entry historyi | Integrated into UniProtKB/Swiss-Prot: | June 16, 2009 |
Last sequence update: | July 24, 2007 | |
Last modified: | December 2, 2020 | |
This is version 45 of the entry and version 1 of the sequence. See complete history. | ||
Entry statusi | Reviewed (UniProtKB/Swiss-Prot) | |
Annotation program | Chordata Protein Annotation Program |
Miscellaneousi
Keywords - Technical termi
Direct protein sequencingDocuments
- SIMILARITY comments
Index of protein domains and families