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Protein

TATA box-binding protein-like protein 2

Gene

Tbpl2

Organism
Rattus norvegicus (Rat)
Status
Reviewed-Annotation score: -Experimental evidence at transcript leveli

Functioni

Transcription factor required in complex with TAF3 for the differentiation of myoblasts into myocytes. The complex replaces TFIID at specific promoters at an early stage in the differentiation process (By similarity).By similarity

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionDevelopmental protein, DNA-binding
Biological processTranscription, Transcription regulation

Names & Taxonomyi

Protein namesi
Recommended name:
TATA box-binding protein-like protein 2
Short name:
TBP-like protein 2
Alternative name(s):
TATA box-binding protein-related factor 3
Short name:
TBP-related factor 3
Gene namesi
Name:Tbpl2By similarity
Synonyms:Tbp2, Trf3By similarity
OrganismiRattus norvegicus (Rat)
Taxonomic identifieri10116 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaMyomorphaMuroideaMuridaeMurinaeRattus
Proteomesi
  • UP000002494 Componenti: Chromosome 3

Organism-specific databases

RGDi1596837 Tbpl2

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Keywords - Cellular componenti

Cytoplasm, Nucleus

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00003181211 – 344TATA box-binding protein-like protein 2Add BLAST344

Proteomic databases

PaxDbiA6H909
PRIDEiA6H909

Interactioni

Subunit structurei

Interacts with TAF3.By similarity

Protein-protein interaction databases

STRINGi10116.ENSRNOP00000039739

Structurei

3D structure databases

ProteinModelPortaliA6H909
SMRiA6H909
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the TBP family.Sequence analysis

Phylogenomic databases

eggNOGiKOG3302 Eukaryota
COG2101 LUCA
GeneTreeiENSGT00410000025389
HOGENOMiHOG000105164
HOVERGENiHBG044997
InParanoidiA6H909
KOiK03120
OMAiMTPVSEC
OrthoDBiEOG091G0ENY
PhylomeDBiA6H909

Family and domain databases

CDDicd04516 TBP_eukaryotes, 1 hit
Gene3Di3.30.310.10, 2 hits
HAMAPiMF_00408 TATA_bind_prot_arch, 1 hit
InterProiView protein in InterPro
IPR000814 TBP
IPR030491 TBP_CS
IPR012295 TBP_dom_sf
IPR033710 TBP_eukaryotic
PANTHERiPTHR10126 PTHR10126, 1 hit
PfamiView protein in Pfam
PF00352 TBP, 2 hits
PRINTSiPR00686 TIFACTORIID
PROSITEiView protein in PROSITE
PS00351 TFIID, 2 hits

Sequencei

Sequence statusi: Complete.

A6H909-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MEEDMYVDIF LDPYTFQDDF PPATSQLFSP GAPLDVHPLN PSNPETVFHS
60 70 80 90 100
HLGAVKKAPS DFSSVDLSFL PDELTQENKD RTVTGNKVTN EESFRTQDWQ
110 120 130 140 150
SQLQLPDEQG SGLNLNSNSS PDTQSCLCSH DADSNQLSSE TPNSNALPVV
160 170 180 190 200
LISSMTPMNP VTECSGIVPQ LQNVVSTANL ACKLDLRKIA LNAKNTEYNP
210 220 230 240 250
KRFAAVIMRI REPRTTALIF SSGKVVCTGA KSEDESRLAA RKYARVVQKL
260 270 280 290 300
GFPVRFFNFK IQNMVASCDV KFPIRLEILA LTHRQFSSYE PELFPGLIYK
310 320 330 340
MVKPQVVLLI FASGKVVLTG AKERSEIYEA FENMYPILES FKKV
Length:344
Mass (Da):38,355
Last modified:July 24, 2007 - v1
Checksum:iCAA7FFAC7482F732
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AAHX01020401 Genomic DNA No translation available.
BK005774 mRNA Translation: DAA06034.1
RefSeqiNP_001092831.1, NM_001099361.1
UniGeneiRn.217494

Genome annotation databases

EnsembliENSRNOT00000050371; ENSRNOP00000039739; ENSRNOG00000033682
GeneIDi680050
KEGGirno:680050
UCSCiRGD:1596837 rat

Similar proteinsi

Entry informationi

Entry nameiTBPL2_RAT
AccessioniPrimary (citable) accession number: A6H909
Entry historyiIntegrated into UniProtKB/Swiss-Prot: February 5, 2008
Last sequence update: July 24, 2007
Last modified: May 23, 2018
This is version 72 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families

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