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Entry version 96 (12 Aug 2020)
Sequence version 1 (24 Jul 2007)
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Protein
Submitted name:

Intersectin 2

Gene

ITSN2

Organism
Homo sapiens (Human)
Status
Unreviewed-Annotation score:

Annotation score:2 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Experimental evidence at transcript leveli <p>This indicates the type of evidence that supports the existence of the protein. Note that the 'protein existence' evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

Caution

Lacks conserved residue(s) required for the propagation of feature annotation.PROSITE-ProRule annotation

Regions

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/function%5Fsection">Function</a> section specifies the position(s) of the calcium-binding region(s) within the protein. One common calcium-binding motif is the EF-hand, but other calcium-binding motifs also exist.<p><a href='/help/ca_bind' target='_top'>More...</a></p>Calcium bindingi66 – 77PROSITE-ProRule annotationAdd BLAST12

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

GO - Biological processi

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywordsi

Biological processEndocytosisARBA annotation
LigandCalciumPROSITE-ProRule annotation, Metal-bindingARBA annotation

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Submitted name:
Intersectin 2Imported
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: 'Name', 'Synonyms', 'Ordered locus names' and 'ORF names'.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:ITSN2Imported
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiHomo sapiens (Human)Imported
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the 'taxonomic identifier' or 'taxid'.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri9606 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo

<p>This section provides information on the disease(s) and phenotype(s) associated with a protein.<p><a href='/help/pathology_and_biotech_section' target='_top'>More...</a></p>Pathology & Biotechi

Organism-specific databases

The Pharmacogenetics and Pharmacogenomics Knowledge Base

More...
PharmGKBi
PA29982

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Proteomic databases

PeptideAtlas

More...
PeptideAtlasi
A6H8W8

PRoteomics IDEntifications database

More...
PRIDEi
A6H8W8

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

Gene expression databases

Genevisible search portal to normalized and curated expression data from Genevestigator

More...
Genevisiblei
A6H8W8, HS

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

GO - Molecular functioni

Protein-protein interaction databases

Protein interaction database and analysis system

More...
IntActi
A6H8W8, 9 interactors

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/family%5Fand%5Fdomains%5Fsection">Family and Domains</a> section describes the position and type of a domain, which is defined as a specific combination of secondary structures organized into a characteristic three-dimensional structure or fold.<p><a href='/help/domain' target='_top'>More...</a></p>Domaini21 – 109EHInterPro annotationAdd BLAST89
Domaini53 – 88EF-handInterPro annotationAdd BLAST36
Domaini243 – 332EHInterPro annotationAdd BLAST90
Domaini276 – 311EF-handInterPro annotationAdd BLAST36
Domaini729 – 790SH3InterPro annotationAdd BLAST62
Domaini870 – 928SH3InterPro annotationAdd BLAST59
Domaini953 – 1011SH3InterPro annotationAdd BLAST59
Domaini1025 – 1089SH3InterPro annotationAdd BLAST65
Domaini1099 – 1158SH3InterPro annotationAdd BLAST60
Domaini1181 – 1367DHInterPro annotationAdd BLAST187
Domaini1406 – 1516PHInterPro annotationAdd BLAST111
Domaini1542 – 1624C2InterPro annotationAdd BLAST83

Region

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Family and Domains' section describes a region of interest that cannot be described in other subsections.<p><a href='/help/region' target='_top'>More...</a></p>Regioni218 – 241DisorderedSequence analysisAdd BLAST24
Regioni349 – 377DisorderedSequence analysisAdd BLAST29
Regioni663 – 724DisorderedSequence analysisAdd BLAST62

Coiled coil

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Family and domains' section denotes the positions of regions of coiled coil within the protein.<p><a href='/help/coiled' target='_top'>More...</a></p>Coiled coili508 – 549Sequence analysisAdd BLAST42
Coiled coili1354 – 1374Sequence analysisAdd BLAST21

Compositional bias

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Family and Domains' section describes the position of regions of compositional bias within the protein and the particular amino acids that are over-represented within those regions.<p><a href='/help/compbias' target='_top'>More...</a></p>Compositional biasi218 – 239PolarSequence analysisAdd BLAST22
Compositional biasi350 – 377PolyampholyteSequence analysisAdd BLAST28

Keywords - Domaini

Coiled coilSequence analysis, SH3 domainPROSITE-ProRule annotationARBA annotation

Phylogenomic databases

KEGG Orthology (KO)

More...
KOi
K20045

Family and domain databases

Conserved Domains Database

More...
CDDi
cd00052, EH, 2 hits
cd00160, RhoGEF, 1 hit
cd11988, SH3_Intersectin2_1, 1 hit
cd11990, SH3_Intersectin2_2, 1 hit
cd11992, SH3_Intersectin2_3, 1 hit
cd11994, SH3_Intersectin2_4, 1 hit
cd11996, SH3_Intersectin2_5, 1 hit

Gene3D Structural and Functional Annotation of Protein Families

More...
Gene3Di
1.20.900.10, 1 hit
2.30.29.30, 1 hit
2.60.40.150, 1 hit

Integrated resource of protein families, domains and functional sites

More...
InterProi
View protein in InterPro
IPR000008, C2_dom
IPR035892, C2_domain_sf
IPR035899, DBL_dom_sf
IPR000219, DH-domain
IPR011992, EF-hand-dom_pair
IPR018247, EF_Hand_1_Ca_BS
IPR002048, EF_hand_dom
IPR000261, EH_dom
IPR027029, Intersectin-2
IPR035737, Intersectin-2_SH3_1
IPR035738, Intersectin-2_SH3_2
IPR035739, Intersectin-2_SH3_3
IPR035740, Intersectin-2_SH3_4
IPR035741, Intersectin-2_SH3_5
IPR011993, PH-like_dom_sf
IPR001849, PH_domain
IPR036028, SH3-like_dom_sf
IPR001452, SH3_domain

The PANTHER Classification System

More...
PANTHERi
PTHR11216:SF29, PTHR11216:SF29, 1 hit

Pfam protein domain database

More...
Pfami
View protein in Pfam
PF00168, C2, 1 hit
PF12763, EF-hand_4, 2 hits
PF16652, PH_13, 1 hit
PF00621, RhoGEF, 1 hit
PF00018, SH3_1, 2 hits
PF07653, SH3_2, 1 hit
PF14604, SH3_9, 2 hits

Protein Motif fingerprint database; a protein domain database

More...
PRINTSi
PR00452, SH3DOMAIN

Simple Modular Architecture Research Tool; a protein domain database

More...
SMARTi
View protein in SMART
SM00239, C2, 1 hit
SM00054, EFh, 2 hits
SM00027, EH, 2 hits
SM00233, PH, 1 hit
SM00325, RhoGEF, 1 hit
SM00326, SH3, 5 hits

Superfamily database of structural and functional annotation

More...
SUPFAMi
SSF47473, SSF47473, 2 hits
SSF48065, SSF48065, 1 hit
SSF50044, SSF50044, 5 hits

PROSITE; a protein domain and family database

More...
PROSITEi
View protein in PROSITE
PS50004, C2, 1 hit
PS50010, DH_2, 1 hit
PS00018, EF_HAND_1, 1 hit
PS50222, EF_HAND_2, 2 hits
PS50031, EH, 2 hits
PS50003, PH_DOMAIN, 1 hit
PS50002, SH3, 5 hits

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence%5Flength">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequencei

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences%5Fsection">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

A6H8W8-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MAQFPTAMNG GPNMWAITSE ERTKHDRQFD NLKPSGGYIT GDQARNFFLQ
60 70 80 90 100
SGLPAPVLAE IWALSDLNKD GKMDQQEFSI AMKLIKLKLQ GQQLPVVLPP
110 120 130 140 150
IMKQPPMFSP LISARFGMGS MPNLSIPQPL PPAAPITSLS SATSGTNLPP
160 170 180 190 200
LMMPTPLVPS VSTSSLPNGT ASLIQPLPIP YSSSTLPHGS SYSLMMGGFG
210 220 230 240 250
GASIQKAQSL IDLGSSSSTS STASLSGNSP KTGTSEWAVP QPTRLKYRQK
260 270 280 290 300
FNTLDKSMSG YLSGFQARNA LLQSNLSQTQ LATIWTLADV DGDGQLKAEE
310 320 330 340 350
FILAMHLTDM AKAGQPLPLT LPPELVPPSF RGGKQIDSIN GTLPSYQKMQ
360 370 380 390 400
EEEPQKKLPV TFEDKRKANY ERGNMELEKR RQALMEQQQR EAERKAQKEK
410 420 430 440 450
EEWERKQREL QEQEWKKQLE LEKRLEKQRE LERQREEERR KDIERREAAK
460 470 480 490 500
QELERQRRLE WERIRRQELL NQKNREQEEI VRLNSKKKNL HLELEALNGK
510 520 530 540 550
HQQISGRLQD VRLKKQTQKT ELEVLDKQCD LEIMEIKQLQ QELQEYQNKL
560 570 580 590 600
IYLVPEKQLL NERIKNMQFS NTPDSGVSLL HKKSLEKEEL CQRLKEQLDA
610 620 630 640 650
LEKETASKLS EMDSFNNQLK ELRETYNTQQ LALEQLYKIK RDKLKEIERK
660 670 680 690 700
RLELMQKKKL EDEAARKAKQ GKENLWKENL RKEEEEKQKR LQEEKTQEKI
710 720 730 740 750
QEEERKAEEK QRKDKDTLKA EEKKRETASV LVNYRALYPF EARNHDEMSF
760 770 780 790 800
NSGDIIQVDE KTVGEPGWLY GSFQGNFGWF PCNYVEKMPS SENEKAVSPK
810 820 830 840 850
KALLPPTVSL SATSTSSEPL SSNQPASVTD YQNVSFSNLT VNTSWQKKSA
860 870 880 890 900
FTRTVSPGSV SPIHGQGQVV ENLKAQALCS WTAKKDNHLN FSKHDIITVL
910 920 930 940 950
EQQENWWFGE VHGGRGWFPK SYVKIIPGSE VKREEPEALY AAVNKKPTSA
960 970 980 990 1000
AYSVGEEYIA LYPYSSVEPG DLTFTEGEEI LVTQKDGEWW TGSIGDRSGI
1010 1020 1030 1040 1050
FPSNYVKPKD QESFGSASKS GASNKKPEIA QVTSAYVASG SEQLSLAPGQ
1060 1070 1080 1090 1100
LILILKKNTS GWWQGELQAR GKKRQKGWFP ASHVKLLGPS SERATPAFHP
1110 1120 1130 1140 1150
VCQVIAMYDY AANNEDELSF SKGQLINVMN KDDPDWWQGE INGVTGLFPS
1160 1170 1180 1190 1200
NYVKMTTDSD PSQQWCADLQ TLDTMQPIER KRQGYIHELI QTEERYMADL
1210 1220 1230 1240 1250
QLVVEVFQKR MAESGFLTEG EMALIFVNWK ELIMSNTKLL KALRVRKKTG
1260 1270 1280 1290 1300
GEKMPVQMIG DILAAELSHM QAYIRFCSCQ LNGAALLQQK TDEDTDFKEF
1310 1320 1330 1340 1350
LKKLASDPRC KGMPLSSFLL KPMQRITRYP LLIRSILENT PESHADHSSL
1360 1370 1380 1390 1400
KLALERAEEL CSQVNEGVRE KENSDRLEWI QAHVQCEGLA EQLIFNSLTN
1410 1420 1430 1440 1450
CLGPRKLLHS GKLYKTKSNK ELHGFLFNDF LLLTYMVKQF AVSSGSEKLF
1460 1470 1480 1490 1500
SSKSNAQFKM YKTPIFLNEV LVKLPTDPSS DEPVFHISHI DRVYTLRTDN
1510 1520 1530 1540 1550
INERTAWVQK IKAASEQYID TEKKQREKAY QARSQKTSGI GRLMVHVIEA
1560 1570 1580 1590 1600
TELKACKPNG KSNPYCEISM GSQSYTTRTI QDTLNPKWNF NCQFFIKDLY
1610 1620 1630 1640 1650
QDVLCLTLFD RDQFSPDDFL GRTEIPVAKI RTEQESKGPM TRRLLLHEVP
1660
TGEVWVRFDL QLFEQKTLL
Length:1,669
Mass (Da):190,365
Last modified:July 24, 2007 - v1
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:i8A2E0E323BAE4E2B
GO

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...
EMBLi

GenBank nucleotide sequence database

More...
GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...
DDBJi
Links Updated
BC146779 mRNA Translation: AAI46780.1

NCBI Reference Sequences

More...
RefSeqi
NP_006268.2, NM_006277.2
NP_062541.3, NM_019595.3

Genome annotation databases

Database of genes from NCBI RefSeq genomes

More...
GeneIDi
50618

KEGG: Kyoto Encyclopedia of Genes and Genomes

More...
KEGGi
hsa:50618

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BC146779 mRNA Translation: AAI46780.1
RefSeqiNP_006268.2, NM_006277.2
NP_062541.3, NM_019595.3

3D structure databases

Database of comparative protein structure models

More...
ModBasei
Search...

SWISS-MODEL Interactive Workspace

More...
SWISS-MODEL-Workspacei
Submit a new modelling project...

Protein-protein interaction databases

IntActiA6H8W8, 9 interactors

Proteomic databases

PeptideAtlasiA6H8W8
PRIDEiA6H8W8

Genome annotation databases

GeneIDi50618
KEGGihsa:50618

Organism-specific databases

Comparative Toxicogenomics Database

More...
CTDi
50618
PharmGKBiPA29982

Phylogenomic databases

KOiK20045

Miscellaneous databases

BioGRID ORCS database of CRISPR phenotype screens

More...
BioGRID-ORCSi
50618, 15 hits in 874 CRISPR screens

ChiTaRS: a database of human, mouse and fruit fly chimeric transcripts and RNA-sequencing data

More...
ChiTaRSi
ITSN2, human

Database of phenotypes from RNA interference screens in Drosophila and Homo sapiens

More...
GenomeRNAii
50618

Gene expression databases

GenevisibleiA6H8W8, HS

Family and domain databases

CDDicd00052, EH, 2 hits
cd00160, RhoGEF, 1 hit
cd11988, SH3_Intersectin2_1, 1 hit
cd11990, SH3_Intersectin2_2, 1 hit
cd11992, SH3_Intersectin2_3, 1 hit
cd11994, SH3_Intersectin2_4, 1 hit
cd11996, SH3_Intersectin2_5, 1 hit
Gene3Di1.20.900.10, 1 hit
2.30.29.30, 1 hit
2.60.40.150, 1 hit
InterProiView protein in InterPro
IPR000008, C2_dom
IPR035892, C2_domain_sf
IPR035899, DBL_dom_sf
IPR000219, DH-domain
IPR011992, EF-hand-dom_pair
IPR018247, EF_Hand_1_Ca_BS
IPR002048, EF_hand_dom
IPR000261, EH_dom
IPR027029, Intersectin-2
IPR035737, Intersectin-2_SH3_1
IPR035738, Intersectin-2_SH3_2
IPR035739, Intersectin-2_SH3_3
IPR035740, Intersectin-2_SH3_4
IPR035741, Intersectin-2_SH3_5
IPR011993, PH-like_dom_sf
IPR001849, PH_domain
IPR036028, SH3-like_dom_sf
IPR001452, SH3_domain
PANTHERiPTHR11216:SF29, PTHR11216:SF29, 1 hit
PfamiView protein in Pfam
PF00168, C2, 1 hit
PF12763, EF-hand_4, 2 hits
PF16652, PH_13, 1 hit
PF00621, RhoGEF, 1 hit
PF00018, SH3_1, 2 hits
PF07653, SH3_2, 1 hit
PF14604, SH3_9, 2 hits
PRINTSiPR00452, SH3DOMAIN
SMARTiView protein in SMART
SM00239, C2, 1 hit
SM00054, EFh, 2 hits
SM00027, EH, 2 hits
SM00233, PH, 1 hit
SM00325, RhoGEF, 1 hit
SM00326, SH3, 5 hits
SUPFAMiSSF47473, SSF47473, 2 hits
SSF48065, SSF48065, 1 hit
SSF50044, SSF50044, 5 hits
PROSITEiView protein in PROSITE
PS50004, C2, 1 hit
PS50010, DH_2, 1 hit
PS00018, EF_HAND_1, 1 hit
PS50222, EF_HAND_2, 2 hits
PS50031, EH, 2 hits
PS50003, PH_DOMAIN, 1 hit
PS50002, SH3, 5 hits

ProtoNet; Automatic hierarchical classification of proteins

More...
ProtoNeti
Search...

MobiDB: a database of protein disorder and mobility annotations

More...
MobiDBi
Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the 'Entry information' section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiA6H8W8_HUMAN
<p>This subsection of the 'Entry information' section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called 'Primary (citable) accession number'.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: A6H8W8
<p>This subsection of the 'Entry information' section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification ('Last modified'). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/TrEMBL: July 24, 2007
Last sequence update: July 24, 2007
Last modified: August 12, 2020
This is version 96 of the entry and version 1 of the sequence. See complete history.
<p>This subsection of the 'Entry information' section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.
UniProt is an ELIXIR core data resource
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