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Protein
Submitted name:

KCNA2 protein

Gene

KCNA2

Organism
Bos taurus (Bovine)
Status
Unreviewed-Annotation score: -Experimental evidence at transcript leveli

Functioni

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionIon channel, Potassium channelSAAS annotation, Voltage-gated channelSAAS annotation
Biological processIon transport, Potassium transport, Transport
LigandPotassium

Names & Taxonomyi

Protein namesi
Submitted name:
KCNA2 proteinImported
Gene namesi
Name:KCNA2Imported
OrganismiBos taurus (Bovine)Imported
Taxonomic identifieri9913 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaLaurasiatheriaCetartiodactylaRuminantiaPecoraBovidaeBovinaeBos

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Transmembranei165 – 188HelicalSequence analysisAdd BLAST24
Transmembranei222 – 243HelicalSequence analysisAdd BLAST22
Transmembranei328 – 349HelicalSequence analysisAdd BLAST22
Transmembranei389 – 410HelicalSequence analysisAdd BLAST22

Keywords - Cellular componenti

Membrane

Structurei

3D structure databases

ProteinModelPortaliA6H7J0
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini33 – 133BTBInterPro annotationAdd BLAST101

Sequence similaritiesi

Belongs to the potassium channel family.SAAS annotation

Keywords - Domaini

Transmembrane, Transmembrane helixSequence analysisSAAS annotation

Phylogenomic databases

eggNOGiKOG1545 Eukaryota
COG1226 LUCA
HOGENOMiHOG000231015
HOVERGENiHBG052230
KOiK04875

Family and domain databases

Gene3Di1.20.120.350, 1 hit
InterProiView protein in InterPro
IPR000210 BTB/POZ_dom
IPR005821 Ion_trans_dom
IPR003968 K_chnl_volt-dep_Kv
IPR003972 K_chnl_volt-dep_Kv1
IPR004049 K_chnl_volt-dep_Kv1.2
IPR011333 SKP1/BTB/POZ_sf
IPR003131 T1-type_BTB
IPR028325 VG_K_chnl
IPR027359 Volt_channel_dom_sf
PANTHERiPTHR11537 PTHR11537, 1 hit
PTHR11537:SF23 PTHR11537:SF23, 1 hit
PfamiView protein in Pfam
PF02214 BTB_2, 1 hit
PF00520 Ion_trans, 1 hit
PRINTSiPR00169 KCHANNEL
PR01509 KV12CHANNEL
PR01491 KVCHANNEL
PR01496 SHAKERCHANEL
SMARTiView protein in SMART
SM00225 BTB, 1 hit
SUPFAMiSSF54695 SSF54695, 1 hit

Sequencei

Sequence statusi: Complete.

A6H7J0-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MTVATGDPAD EAAALPGHPQ DTYDPEADHE CCERVVINIS GLRFETQLKT
60 70 80 90 100
LAQFPETLLG DPKKRMRYFD PLRNEYFFDR NRPSFDAILY YYQSGGRLRR
110 120 130 140 150
PVNVPLDIFS EEIRFYELGE EAMEMFREDE GYIKEEERPL PENEFQRQVW
160 170 180 190 200
LLFEYPESSG PARIIAIESV MVILISIVSF CLETLPIFRD ENEDMHGSGV
210 220 230 240 250
TFHTYSNSTI GYQQSTSFTD PFFIVETLCI IWFSFEFLVR FFACPSKAGF
260 270 280 290 300
FTNIMNIIDI VAIIPYFITL GTELAEKPED AQQGQQAMSL AILRVIRLVR
310 320 330 340 350
VFRIFKLSRH SKGLQILGQT LKASMRELGL LIFFLFIGVI LFSSAVYFAE
360 370 380 390 400
ADERESQFPS IPDAFWWAVV SMTTVGYGDM VPTTIGGKIV GSLCAIAGVL
410 420 430 440 450
TIALPVPVIV SNFNYFYHRE TEGEEQAQYL QVTSCPKIPS SPDLKKSRSA
460 470 480 490
STISKSDYME IQEGVNNSNE DFREENLKTA NCTLANTNYV NITKMLTDV
Length:499
Mass (Da):56,747
Last modified:July 24, 2007 - v1
Checksum:iFF9F9F5799BC4A9A
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BC146265 mRNA Translation: AAI46266.1
RefSeqiNP_001094665.1, NM_001101195.2
UniGeneiBt.47448

Genome annotation databases

GeneIDi539608
KEGGibta:539608

Similar proteinsi

Entry informationi

Entry nameiA6H7J0_BOVIN
AccessioniPrimary (citable) accession number: A6H7J0
Entry historyiIntegrated into UniProtKB/TrEMBL: July 24, 2007
Last sequence update: July 24, 2007
Last modified: February 28, 2018
This is version 72 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

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