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Protein
Submitted name:

LD36265p

Gene

UGP

Organism
Drosophila melanogaster (Fruit fly)
Status
Unreviewed-Annotation score:

Annotation score:2 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Experimental evidence at protein leveli <p>This indicates the type of evidence that supports the existence of the protein. Note that the ‘protein existence’ evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Function’ section describes the interaction between a single amino acid and another chemical entity. Priority is given to the annotation of physiological ligands.<p><a href='/help/binding' target='_top'>More...</a></p>Binding sitei129UTPUniRule annotation1
Binding sitei192UTPUniRule annotation1
Binding sitei223UTP; via amide nitrogenUniRule annotation1
Binding sitei224SubstrateUniRule annotation1
Binding sitei254UTPUniRule annotation1
Binding sitei398UTPUniRule annotation1

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

GO - Biological processi

  • glycogen metabolic process Source: GO_Central
  • response to hyperoxia Source: FlyBase
  • UDP-glucose metabolic process Source: FlyBase

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywordsi

Molecular functionNucleotidyltransferaseImported, Transferase

Enzyme and pathway databases

BRENDA Comprehensive Enzyme Information System

More...
BRENDAi
2.7.7.9 1994

Reactome - a knowledgebase of biological pathways and processes

More...
Reactomei
R-DME-173599 Formation of the active cofactor, UDP-glucuronate
R-DME-3322077 Glycogen synthesis

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Submitted name:
LD36265pImported
Submitted name:
UGPImported
Submitted name:
UGP, isoform DImported (EC:2.7.7.9Imported)
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: ‘Name’, ‘Synonyms’, ‘Ordered locus names’ and ‘ORF names’.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:UGPImported
Synonyms:Dmel\CG4347Imported, dUGPImported, UDPGPPImported, UGP-RDImported, UGPaseImported
ORF Names:CG4347Imported, Dmel_CG4347Imported
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiDrosophila melanogaster (Fruit fly)Imported
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the ‘taxonomic identifier’ or ‘taxid’.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri7227 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryotaMetazoaEcdysozoaArthropodaHexapodaInsectaPterygotaNeopteraHolometabolaDipteraBrachyceraMuscomorphaEphydroideaDrosophilidaeDrosophilaSophophora
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000000803 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes_manual">proteome</a> can consist of several components. <br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome 3L

Organism-specific databases

Drosophila genome database

More...
FlyBasei
FBgn0035978 UGP

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

Gene expression databases

Bgee dataBase for Gene Expression Evolution

More...
Bgeei
FBgn0035978 Expressed in 19 organ(s), highest expression level in capitellum (Drosophila)

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

Protein-protein interaction databases

Protein interaction database and analysis system

More...
IntActi
A5XCL5, 6 interactors

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

More...
eggNOGi
KOG2638 Eukaryota
COG4284 LUCA

Ensembl GeneTree

More...
GeneTreei
ENSGT00940000153464

KEGG Orthology (KO)

More...
KOi
K00963

Database of Orthologous Groups

More...
OrthoDBi
EOG091G04UI

Family and domain databases

Conserved Domains Database

More...
CDDi
cd00897 UGPase_euk, 1 hit

Gene3D Structural and Functional Annotation of Protein Families

More...
Gene3Di
3.90.550.10, 1 hit

Integrated resource of protein families, domains and functional sites

More...
InterProi
View protein in InterPro
IPR029044 Nucleotide-diphossugar_trans
IPR002618 UDPGP_fam
IPR016267 UDPGP_trans

Pfam protein domain database

More...
Pfami
View protein in Pfam
PF01704 UDPGP, 1 hit

PIRSF; a whole-protein classification database

More...
PIRSFi
PIRSF000806 UDPGP, 1 hit

Superfamily database of structural and functional annotation

More...
SUPFAMi
SSF53448 SSF53448, 1 hit

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence_length">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>.<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequence (1+)i

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences_section">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Fragment.

This entry has 1 described isoform and 3 potential isoforms that are computationally mapped.Show allAlign All

A5XCL5-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MLDVPHEAKV RGHQRAPSDS KEFHEVTKRD ALRLLEHDVD RLLETTEKAR
60 70 80 90 100
QPALKAEMGR FADLFGRFIQ EEGPALDWNK IQKLPENAVM NYSNLKSPKN
110 120 130 140 150
EQIRNMLDKL VVIKLNGGLG TSMGCHGPKS VIPVRSDLTF LDLTVQQIEH
160 170 180 190 200
LNKTYDANVP LVLMNSFNTD EDTEKIVRKY KGFRVQIHTF NQSCFPRISR
210 220 230 240 250
EHYLPVAKDF DVEKDMEAWY PPGHGDFYDT FRNSGLLKKF IEEGREYCFL
260 270 280 290 300
SNIDNLGATV DLNILNKLVG EERATTPVEF VMEVTDKTRA DVKGGTLIQM
310 320 330 340 350
ENKLRLLEIA QVPPEHVDDF KSVKTFKFFN TNNIWANLAA IDRVLRERTL
360 370 380 390 400
NMEIIVNNKT LENGTRVIQL ETAVGAAMKC FDGAIGINVP RSRFLPVKKS
410 420 430 440 450
SDLLLVMSNL YTLKNGSLVM SPQRMFPTTP LVKLGENHFS KVKEFLGRFA
460 470 480 490 500
NIPDIIELDH LTVSGDVTFG RGVSLRGTVI IIANHGDRID IPAGAILENK
510
IVSGNMRILD H
Length:511
Mass (Da):57,825
Last modified:July 10, 2007 - v1
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:i5901C7F2E0B4149B
GO

<p>In eukaryotic reference proteomes, unreviewed entries that are likely to belong to the same gene are computationally mapped, based on gene identifiers from Ensembl, EnsemblGenomes and model organism databases.<p><a href='/help/gene_centric_isoform_mapping' target='_top'>More...</a></p>Computationally mapped potential isoform sequencesi

There are 3 potential isoforms mapped to this entry.BLASTAlignShow allAdd to basket
EntryEntry nameProtein names
Gene namesLengthAnnotation
E1JI91E1JI91_DROME
UTP--glucose-1-phosphate uridylyltr...
UGP Dmel\CG4347, dUGP, UDPGPP, UGP-RE, UGPase
518Annotation score:

Annotation score:3 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
Q9VSW1Q9VSW1_DROME
UTP--glucose-1-phosphate uridylyltr...
UGP Dmel\CG4347, dUGP, UDPGPP, UGPase, CG4347
520Annotation score:

Annotation score:3 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
Q9VSW2Q9VSW2_DROME
UTP--glucose-1-phosphate uridylyltr...
UGP Dmel\CG4347, dUGP, UDPGPP, UGPase, CG4347
513Annotation score:

Annotation score:3 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Sequence’ section is used for sequence fragments to indicate that the residue at the extremity of the sequence is not the actual terminal residue in the complete protein sequence.<p><a href='/help/non_ter' target='_top'>More...</a></p>Non-terminal residuei511Imported1

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...
EMBLi

GenBank nucleotide sequence database

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GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...
DDBJi
Links Updated
DQ864016 Genomic DNA Translation: ABH06651.1
DQ864017 Genomic DNA Translation: ABH06652.1
DQ864018 Genomic DNA Translation: ABH06653.1
DQ864019 Genomic DNA Translation: ABH06654.1
DQ864020 Genomic DNA Translation: ABH06655.1
DQ864021 Genomic DNA Translation: ABH06656.1
DQ864022 Genomic DNA Translation: ABH06657.1
DQ864023 Genomic DNA Translation: ABH06658.1
DQ864024 Genomic DNA Translation: ABH06659.1
DQ864025 Genomic DNA Translation: ABH06660.1
DQ864026 Genomic DNA Translation: ABH06661.1
DQ864027 Genomic DNA Translation: ABH06662.1
DQ864028 Genomic DNA Translation: ABH06663.1
DQ864029 Genomic DNA Translation: ABH06664.1
DQ864030 Genomic DNA Translation: ABH06665.1
DQ864031 Genomic DNA Translation: ABH06666.1
DQ864032 Genomic DNA Translation: ABH06667.1
DQ864033 Genomic DNA Translation: ABH06668.1
DQ864034 Genomic DNA Translation: ABH06669.1
DQ864035 Genomic DNA Translation: ABH06670.1
DQ864036 Genomic DNA Translation: ABH06671.1
DQ864037 Genomic DNA Translation: ABH06672.1
DQ864038 Genomic DNA Translation: ABH06673.1
DQ864039 Genomic DNA Translation: ABH06674.1
DQ864040 Genomic DNA Translation: ABH06675.1
DQ864041 Genomic DNA Translation: ABH06676.1
AE014296 Genomic DNA Translation: ACZ94670.1
BT125863 mRNA Translation: ADU79251.1

NCBI Reference Sequences

More...
RefSeqi
NP_001163399.1, NM_001169928.2

UniGene gene-oriented nucleotide sequence clusters

More...
UniGenei
Dm.903

Genome annotation databases

Ensembl metazoan genome annotation project

More...
EnsemblMetazoai
FBtr0301698; FBpp0290912; FBgn0035978

Database of genes from NCBI RefSeq genomes

More...
GeneIDi
39065

KEGG: Kyoto Encyclopedia of Genes and Genomes

More...
KEGGi
dme:Dmel_CG4347

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
DQ864016 Genomic DNA Translation: ABH06651.1
DQ864017 Genomic DNA Translation: ABH06652.1
DQ864018 Genomic DNA Translation: ABH06653.1
DQ864019 Genomic DNA Translation: ABH06654.1
DQ864020 Genomic DNA Translation: ABH06655.1
DQ864021 Genomic DNA Translation: ABH06656.1
DQ864022 Genomic DNA Translation: ABH06657.1
DQ864023 Genomic DNA Translation: ABH06658.1
DQ864024 Genomic DNA Translation: ABH06659.1
DQ864025 Genomic DNA Translation: ABH06660.1
DQ864026 Genomic DNA Translation: ABH06661.1
DQ864027 Genomic DNA Translation: ABH06662.1
DQ864028 Genomic DNA Translation: ABH06663.1
DQ864029 Genomic DNA Translation: ABH06664.1
DQ864030 Genomic DNA Translation: ABH06665.1
DQ864031 Genomic DNA Translation: ABH06666.1
DQ864032 Genomic DNA Translation: ABH06667.1
DQ864033 Genomic DNA Translation: ABH06668.1
DQ864034 Genomic DNA Translation: ABH06669.1
DQ864035 Genomic DNA Translation: ABH06670.1
DQ864036 Genomic DNA Translation: ABH06671.1
DQ864037 Genomic DNA Translation: ABH06672.1
DQ864038 Genomic DNA Translation: ABH06673.1
DQ864039 Genomic DNA Translation: ABH06674.1
DQ864040 Genomic DNA Translation: ABH06675.1
DQ864041 Genomic DNA Translation: ABH06676.1
AE014296 Genomic DNA Translation: ACZ94670.1
BT125863 mRNA Translation: ADU79251.1
RefSeqiNP_001163399.1, NM_001169928.2
UniGeneiDm.903

3D structure databases

Database of comparative protein structure models

More...
ModBasei
Search...

MobiDB: a database of protein disorder and mobility annotations

More...
MobiDBi
Search...

Protein-protein interaction databases

IntActiA5XCL5, 6 interactors

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblMetazoaiFBtr0301698; FBpp0290912; FBgn0035978
GeneIDi39065
KEGGidme:Dmel_CG4347

Organism-specific databases

Comparative Toxicogenomics Database

More...
CTDi
39065
FlyBaseiFBgn0035978 UGP

Phylogenomic databases

eggNOGiKOG2638 Eukaryota
COG4284 LUCA
GeneTreeiENSGT00940000153464
KOiK00963
OrthoDBiEOG091G04UI

Enzyme and pathway databases

BRENDAi2.7.7.9 1994
ReactomeiR-DME-173599 Formation of the active cofactor, UDP-glucuronate
R-DME-3322077 Glycogen synthesis

Miscellaneous databases

ChiTaRS: a database of human, mouse and fruit fly chimeric transcripts and RNA-sequencing data

More...
ChiTaRSi
UGP fly

Database of phenotypes from RNA interference screens in Drosophila and Homo sapiens

More...
GenomeRNAii
39065

Gene expression databases

BgeeiFBgn0035978 Expressed in 19 organ(s), highest expression level in capitellum (Drosophila)

Family and domain databases

CDDicd00897 UGPase_euk, 1 hit
Gene3Di3.90.550.10, 1 hit
InterProiView protein in InterPro
IPR029044 Nucleotide-diphossugar_trans
IPR002618 UDPGP_fam
IPR016267 UDPGP_trans
PfamiView protein in Pfam
PF01704 UDPGP, 1 hit
PIRSFiPIRSF000806 UDPGP, 1 hit
SUPFAMiSSF53448 SSF53448, 1 hit

ProtoNet; Automatic hierarchical classification of proteins

More...
ProtoNeti
Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the ‘Entry information’ section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiA5XCL5_DROME
<p>This subsection of the ‘Entry information’ section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called ‘Primary (citable) accession number’.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: A5XCL5
<p>This subsection of the ‘Entry information’ section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification (‘Last modified’). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/TrEMBL: July 10, 2007
Last sequence update: July 10, 2007
Last modified: December 5, 2018
This is version 99 of the entry and version 1 of the sequence. See complete history.
<p>This subsection of the ‘Entry information’ section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiUnreviewed (UniProtKB/TrEMBL)

<p>This section contains any relevant information that doesn’t fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Complete proteome, Proteomics identificationCombined sources, Reference proteomeImported
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