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Protein

UDP-N-acetylglucosamine--N-acetylmuramyl-(pentapeptide) pyrophosphoryl-undecaprenol N-acetylglucosamine transferase

Gene

murG

Organism
Psychrobacter sp. (strain PRwf-1)
Status
Unreviewed-Annotation score: -Protein inferred from homologyi

Functioni

Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc-(pentapeptide)GlcNAc (lipid intermediate II).UniRule annotationSAAS annotation

Catalytic activityi

UDP-N-acetylglucosamine + Mur2Ac(oyl-L-Ala-gamma-D-Glu-L-Lys-D-Ala-D-Ala)-diphosphoundecaprenol = UDP + GlcNAc-(1->4)-Mur2Ac(oyl-L-Ala-gamma-D-Glu-L-Lys-D-Ala-D-Ala)-diphosphoundecaprenol.UniRule annotationSAAS annotation

Pathwayi: peptidoglycan biosynthesis

This protein is involved in the pathway peptidoglycan biosynthesis, which is part of Cell wall biogenesis.UniRule annotationSAAS annotation
View all proteins of this organism that are known to be involved in the pathway peptidoglycan biosynthesis and in Cell wall biogenesis.

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionGlycosyltransferaseUniRule annotationSAAS annotationImported, Transferase
Biological processCell cycle, Cell divisionUniRule annotationSAAS annotation, Cell shape, Cell wall biogenesis/degradationUniRule annotationSAAS annotation, Peptidoglycan synthesisUniRule annotationSAAS annotation

Enzyme and pathway databases

UniPathwayi
UPA00219

Protein family/group databases

CAZyiGT28 Glycosyltransferase Family 28

Names & Taxonomyi

Protein namesi
Recommended name:
UDP-N-acetylglucosamine--N-acetylmuramyl-(pentapeptide) pyrophosphoryl-undecaprenol N-acetylglucosamine transferaseUniRule annotationSAAS annotation (EC:2.4.1.227UniRule annotationSAAS annotation)
Alternative name(s):
Undecaprenyl-PP-MurNAc-pentapeptide-UDPGlcNAc GlcNAc transferaseUniRule annotation
Gene namesi
Name:murGUniRule annotation
Ordered Locus Names:PsycPRwf_0524Imported
OrganismiPsychrobacter sp. (strain PRwf-1)Imported
Taxonomic identifieri349106 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaPseudomonadalesMoraxellaceaePsychrobacter
Proteomesi
  • UP000001993 Componenti: Chromosome

Subcellular locationi

GO - Cellular componenti

Keywords - Cellular componenti

Cell inner membraneUniRule annotation, Cell membrane, Membrane

Interactioni

Protein-protein interaction databases

STRINGi349106.PsycPRwf_0524

Structurei

3D structure databases

ProteinModelPortaliA5WCT8
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini26 – 163Glyco_transf_28InterPro annotationAdd BLAST138
Domaini212 – 364Glyco_tran_28_CInterPro annotationAdd BLAST153

Sequence similaritiesi

Belongs to the glycosyltransferase 28 family. MurG subfamily.UniRule annotationSAAS annotation

Phylogenomic databases

eggNOGiENOG4105DVQ Bacteria
COG0707 LUCA
HOGENOMiHOG000218321
KOiK02563
OMAiHQTKNAM
OrthoDBiPOG091H02FX

Family and domain databases

CDDicd03785 GT1_MurG, 1 hit
HAMAPiMF_00033 MurG, 1 hit
InterProiView protein in InterPro
IPR006009 GlcNAc_MurG
IPR007235 Glyco_trans_28_C
IPR004276 GlycoTrans_28_N
PfamiView protein in Pfam
PF04101 Glyco_tran_28_C, 1 hit
PF03033 Glyco_transf_28, 1 hit
TIGRFAMsiTIGR01133 murG, 1 hit

Sequencei

Sequence statusi: Complete.

A5WCT8-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MSESAAVQTS APTSPSTSSS VKTPKVLMMA AGTGGHVFPA LAVAEELTRR
60 70 80 90 100
GAEVHWLGTP HGMENDLVRP VGYTFHTIDM QGLRGKGVGR LLKMPFTLSQ
110 120 130 140 150
AMLASIKVIK SNQIDVVVGF GGYVSAPGGL AAKATGTPLI IHEQNAIAGM
160 170 180 190 200
SNRYLAKIAT KVLQAFPNTF GDSDSAENPK LETVGNPVRE AICEIEPPEK
210 220 230 240 250
RYDLNDESPL KLLVVGGSLG AEALNRTVPA ALAQIDKPIA VHHQCGRNNL
260 270 280 290 300
DSTQGYYQAV DRAVHTVTVK PFIDDMAAAY AWADVIVCRA GALTVTEIQN
310 320 330 340 350
VGLSAIFVPL PHAVDDHQTA NARSLAIEDA AYLIPQSKLT PEYLAQTLLD
360 370 380
LDREKCQSMA KKGKALANPG STVVTADFVW EQAIR
Length:385
Mass (Da):40,973
Last modified:July 10, 2007 - v1
Checksum:iB08CFBA76C7AE332
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP000713 Genomic DNA Translation: ABQ93479.1

Genome annotation databases

EnsemblBacteriaiABQ93479; ABQ93479; PsycPRwf_0524
KEGGiprw:PsycPRwf_0524

Entry informationi

Entry nameiA5WCT8_PSYWF
AccessioniPrimary (citable) accession number: A5WCT8
Entry historyiIntegrated into UniProtKB/TrEMBL: July 10, 2007
Last sequence update: July 10, 2007
Last modified: June 20, 2018
This is version 79 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteomeImported
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health

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