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Protein

Probable transaldolase

Gene

tal

Organism
Sphingomonas wittichii (strain RW1 / DSM 6014 / JCM 10273)
Status
Reviewed-Annotation score: -Protein inferred from homologyi

Functioni

Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway.UniRule annotation

Catalytic activityi

Sedoheptulose 7-phosphate + D-glyceraldehyde 3-phosphate = D-erythrose 4-phosphate + D-fructose 6-phosphate.UniRule annotation

Pathwayi: pentose phosphate pathway

This protein is involved in step 2 of the subpathway that synthesizes D-glyceraldehyde 3-phosphate and beta-D-fructose 6-phosphate from D-ribose 5-phosphate and D-xylulose 5-phosphate (non-oxidative stage).UniRule annotation
Proteins known to be involved in the 3 steps of the subpathway in this organism are:
  1. no protein annotated in this organism
  2. Probable transaldolase (tal)
  3. no protein annotated in this organism
This subpathway is part of the pathway pentose phosphate pathway, which is itself part of Carbohydrate degradation.
View all proteins of this organism that are known to be involved in the subpathway that synthesizes D-glyceraldehyde 3-phosphate and beta-D-fructose 6-phosphate from D-ribose 5-phosphate and D-xylulose 5-phosphate (non-oxidative stage), the pathway pentose phosphate pathway and in Carbohydrate degradation.

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Active sitei83Schiff-base intermediate with substrateUniRule annotation1

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionTransferase
Biological processPentose shunt
LigandSchiff base

Enzyme and pathway databases

UniPathwayiUPA00115; UER00414

Names & Taxonomyi

Protein namesi
Recommended name:
Probable transaldolaseUniRule annotation (EC:2.2.1.2UniRule annotation)
Gene namesi
Name:talUniRule annotation
Ordered Locus Names:Swit_0219
OrganismiSphingomonas wittichii (strain RW1 / DSM 6014 / JCM 10273)
Taxonomic identifieri392499 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaAlphaproteobacteriaSphingomonadalesSphingomonadaceaeSphingomonas
Proteomesi
  • UP000001989 Componenti: Chromosome

Subcellular locationi

  • Cytoplasm UniRule annotation

GO - Cellular componenti

Keywords - Cellular componenti

Cytoplasm

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_10001263581 – 217Probable transaldolaseAdd BLAST217

Interactioni

Protein-protein interaction databases

STRINGi392499.Swit_0219

Structurei

3D structure databases

ProteinModelPortaliA5V2S4
SMRiA5V2S4
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the transaldolase family. Type 3B subfamily.UniRule annotation

Phylogenomic databases

eggNOGiENOG4105CW3 Bacteria
COG0176 LUCA
HOGENOMiHOG000226073
KOiK00616
OMAiVRHPMHV
OrthoDBiPOG091H04ZO

Family and domain databases

CDDicd00956 Transaldolase_FSA, 1 hit
Gene3Di3.20.20.70, 1 hit
HAMAPiMF_00494 Transaldolase_3b, 1 hit
InterProiView protein in InterPro
IPR013785 Aldolase_TIM
IPR001585 TAL/FSA
IPR022999 Transaldolase_3B
IPR004731 Transaldolase_3B/F6P_aldolase
IPR018225 Transaldolase_AS
IPR033919 TSA/FSA_arc/bac
PANTHERiPTHR10683 PTHR10683, 2 hits
PfamiView protein in Pfam
PF00923 TAL_FSA, 1 hit
TIGRFAMsiTIGR00875 fsa_talC_mipB, 1 hit
PROSITEiView protein in PROSITE
PS01054 TRANSALDOLASE_1, 1 hit

Sequencei

Sequence statusi: Complete.

A5V2S4-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MKFFVDTADT ADIAEMAATG LLDGVTTNPS LIAKSGKQFV DVIAEICKIV
60 70 80 90 100
PGPVSAEVVA LDHATMMKEA EVLRKIADNV CIKVPLTIDG LKTCKALSDD
110 120 130 140 150
GTMVNVTLCF SANQALLAGK AGAAFISPFV GRHDDVGLDG MGLIADIRQI
160 170 180 190 200
YDNYDFGTEI LVASVRHPIH ILESAKIGAD VMTAPPAVIR ALFNHPLTDK
210
GIQGFMADWA KTGQSIL
Length:217
Mass (Da):22,970
Last modified:July 10, 2007 - v1
Checksum:iE10384B447689BAA
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP000699 Genomic DNA Translation: ABQ66590.1
RefSeqiWP_011951070.1, NC_009511.1

Genome annotation databases

EnsemblBacteriaiABQ66590; ABQ66590; Swit_0219
KEGGiswi:Swit_0219

Similar proteinsi

Entry informationi

Entry nameiTAL_SPHWW
AccessioniPrimary (citable) accession number: A5V2S4
Entry historyiIntegrated into UniProtKB/Swiss-Prot: April 14, 2009
Last sequence update: July 10, 2007
Last modified: May 23, 2018
This is version 73 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. PATHWAY comments
    Index of metabolic and biosynthesis pathways
  2. SIMILARITY comments
    Index of protein domains and families

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