UniProtKB - A5PMC4 (A5PMC4_DANRE)
Protein
Submitted name:
Lectin, mannose-binding 2
Gene
lman2
Organism
Danio rerio (Zebrafish) (Brachydanio rerio)
Status
Functioni
GO - Molecular functioni
- mannose binding Source: GO_Central
GO - Biological processi
- endoplasmic reticulum organization Source: GO_Central
- endoplasmic reticulum to Golgi vesicle-mediated transport Source: GO_Central
- Golgi organization Source: GO_Central
Enzyme and pathway databases
Reactomei | R-DRE-204005, COPII-mediated vesicle transport R-DRE-5694530, Cargo concentration in the ER |
Names & Taxonomyi
Protein namesi | Submitted name: Lectin, mannose-binding 2Imported |
Gene namesi | Name:lman2Imported |
Organismi | Danio rerio (Zebrafish) (Brachydanio rerio)Imported |
Taxonomic identifieri | 7955 [NCBI] |
Taxonomic lineagei | Eukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Actinopterygii › Neopterygii › Teleostei › Ostariophysi › Cypriniformes › Danionidae › Danioninae › Danio |
Proteomesi |
|
Organism-specific databases
ZFINi | ZDB-GENE-070209-149, lman2 |
Subcellular locationi
Endoplasmic reticulum
- endoplasmic reticulum membrane Source: GO_Central
Golgi apparatus
- Golgi membrane Source: GO_Central
Other locations
- COPII-coated ER to Golgi transport vesicle Source: GO_Central
- endoplasmic reticulum-Golgi intermediate compartment Source: GO_Central
- integral component of membrane Source: UniProtKB-KW
Topology
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Transmembranei | 321 – 343 | HelicalSequence analysisAdd BLAST | 23 |
Keywords - Cellular componenti
MembranePTM / Processingi
Molecule processing
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Signal peptidei | 1 – 41 | Sequence analysisAdd BLAST | 41 | |
ChainiPRO_5002686207 | 42 – 354 | Sequence analysisAdd BLAST | 313 |
Proteomic databases
PaxDbi | A5PMC4 |
PeptideAtlasi | A5PMC4 |
Expressioni
Gene expression databases
Bgeei | ENSDARG00000061854, Expressed in gastrula and 33 other tissues |
Family & Domainsi
Domains and Repeats
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Domaini | 49 – 274 | L-type lectin-likeInterPro annotationAdd BLAST | 226 |
Keywords - Domaini
SignalSequence analysisARBA annotation, Transmembrane, Transmembrane helixSequence analysisPhylogenomic databases
eggNOGi | KOG3839, Eukaryota |
GeneTreei | ENSGT00940000158355 |
HOGENOMi | CLU_041093_0_0_1 |
InParanoidi | A5PMC4 |
OMAi | GFAMWIT |
OrthoDBi | 1377709at2759 |
TreeFami | TF313311 |
Family and domain databases
CDDi | cd06901, lectin_VIP36_VIPL, 1 hit |
InterProi | View protein in InterPro IPR013320, ConA-like_dom_sf IPR005052, Lectin_leg IPR035664, VIP36_lectin |
Pfami | View protein in Pfam PF03388, Lectin_leg-like, 1 hit |
SUPFAMi | SSF49899, SSF49899, 1 hit |
PROSITEi | View protein in PROSITE PS51328, L_LECTIN_LIKE, 1 hit |
i Sequence
Sequence statusi: Complete.
A5PMC4-1 [UniParc]FASTAAdd to basket
10 20 30 40 50
MTRERSPALW LHPQPSVSRK MPVCHKILLL LWLLHFSSVY SDITDGNAEH
60 70 80 90 100
LKREHSLIKP YQGVGSSPSS QWDFWGSTLV TSQYVRLTPD ERSKQGSIWN
110 120 130 140 150
TVPCYLKDWE MHVQFKIHGS GKKNLHGDGF AMWYTKERLH PGPVFGNQDH
160 170 180 190 200
FVGLAIFVDT FRNDLQGMDR SFPYISAMVN NGSLPYEHGK DGRSTELGGC
210 220 230 240 250
SVEVRNKEHD TYLAIRYSKG RLTIMVDVDD QNDWKECVDI GGVRLPTGYY
260 270 280 290 300
FGASAATGDL SDNHDIISMK MYQLMVEHTL EEDSQDWTKI EPSVSLLKSP
310 320 330 340 350
KDNIDDPTGN FRSSPLTGWK VFLLLLCALL GIVVCAVVGA VVFQKRQERN
KRFY
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | BX323077 Genomic DNA No translation available. |
RefSeqi | NP_001075216.2, NM_001081747.2 |
Genome annotation databases
Ensembli | ENSDART00000088690; ENSDARP00000083123; ENSDARG00000061854 |
GeneIDi | 557960 |
KEGGi | dre:557960 |
Similar proteinsi
Cross-referencesi
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | BX323077 Genomic DNA No translation available. |
RefSeqi | NP_001075216.2, NM_001081747.2 |
3D structure databases
ModBasei | Search... |
SWISS-MODEL-Workspacei | Submit a new modelling project... |
Protein-protein interaction databases
STRINGi | 7955.ENSDARP00000083123 |
Proteomic databases
PaxDbi | A5PMC4 |
PeptideAtlasi | A5PMC4 |
Genome annotation databases
Ensembli | ENSDART00000088690; ENSDARP00000083123; ENSDARG00000061854 |
GeneIDi | 557960 |
KEGGi | dre:557960 |
Organism-specific databases
CTDi | 10960 |
ZFINi | ZDB-GENE-070209-149, lman2 |
Phylogenomic databases
eggNOGi | KOG3839, Eukaryota |
GeneTreei | ENSGT00940000158355 |
HOGENOMi | CLU_041093_0_0_1 |
InParanoidi | A5PMC4 |
OMAi | GFAMWIT |
OrthoDBi | 1377709at2759 |
TreeFami | TF313311 |
Enzyme and pathway databases
Reactomei | R-DRE-204005, COPII-mediated vesicle transport R-DRE-5694530, Cargo concentration in the ER |
Gene expression databases
Bgeei | ENSDARG00000061854, Expressed in gastrula and 33 other tissues |
Family and domain databases
CDDi | cd06901, lectin_VIP36_VIPL, 1 hit |
InterProi | View protein in InterPro IPR013320, ConA-like_dom_sf IPR005052, Lectin_leg IPR035664, VIP36_lectin |
Pfami | View protein in Pfam PF03388, Lectin_leg-like, 1 hit |
SUPFAMi | SSF49899, SSF49899, 1 hit |
PROSITEi | View protein in PROSITE PS51328, L_LECTIN_LIKE, 1 hit |
ProtoNeti | Search... |
MobiDBi | Search... |
Entry informationi
Entry namei | A5PMC4_DANRE | |
Accessioni | A5PMC4Primary (citable) accession number: A5PMC4 | |
Entry historyi | Integrated into UniProtKB/TrEMBL: | July 10, 2007 |
Last sequence update: | July 10, 2007 | |
Last modified: | December 2, 2020 | |
This is version 85 of the entry and version 1 of the sequence. See complete history. | ||
Entry statusi | Unreviewed (UniProtKB/TrEMBL) |