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Protein

Protein FAM149A

Gene

FAM149A

Organism
Homo sapiens (Human)
Status
Reviewed-Annotation score:

Annotation score:3 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Experimental evidence at transcript leveli <p>This indicates the type of evidence that supports the existence of the protein. Note that the ‘protein existence’ evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Recommended name:
Protein FAM149A
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: ‘Name’, ‘Synonyms’, ‘Ordered locus names’ and ‘ORF names’.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:FAM149A
ORF Names:MST119
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiHomo sapiens (Human)
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the ‘taxonomic identifier’ or ‘taxid’.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri9606 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000005640 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes_manual">proteome</a> can consist of several components. <br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome 4

Organism-specific databases

Eukaryotic Pathogen Database Resources

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EuPathDBi
HostDB:ENSG00000109794.13

Human Gene Nomenclature Database

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HGNCi
HGNC:24527 FAM149A

neXtProt; the human protein knowledge platform

More...
neXtProti
NX_A5PLN7

<p>This section provides information on the disease(s) and phenotype(s) associated with a protein.<p><a href='/help/pathology_and_biotech_section' target='_top'>More...</a></p>Pathology & Biotechi

Organism-specific databases

Open Targets

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OpenTargetsi
ENSG00000109794

The Pharmacogenetics and Pharmacogenomics Knowledge Base

More...
PharmGKBi
PA162386366

Polymorphism and mutation databases

BioMuta curated single-nucleotide variation and disease association database

More...
BioMutai
FAM149A

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘PTM / Processing’ section describes the extent of a polypeptide chain in the mature protein following processing.<p><a href='/help/chain' target='_top'>More...</a></p>ChainiPRO_00003199301 – 773Protein FAM149AAdd BLAST773

Proteomic databases

jPOST - Japan Proteome Standard Repository/Database

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jPOSTi
A5PLN7

PaxDb, a database of protein abundance averages across all three domains of life

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PaxDbi
A5PLN7

PRoteomics IDEntifications database

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PRIDEi
A5PLN7

ProteomicsDB human proteome resource

More...
ProteomicsDBi
740
741 [A5PLN7-2]
742 [A5PLN7-3]
743 [A5PLN7-4]

PTM databases

iPTMnet integrated resource for PTMs in systems biology context

More...
iPTMneti
A5PLN7

Comprehensive resource for the study of protein post-translational modifications (PTMs) in human, mouse and rat.

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PhosphoSitePlusi
A5PLN7

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

Gene expression databases

Bgee dataBase for Gene Expression Evolution

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Bgeei
ENSG00000109794 Expressed in 205 organ(s), highest expression level in nucleus accumbens

CleanEx database of gene expression profiles

More...
CleanExi
HS_FAM149A

ExpressionAtlas, Differential and Baseline Expression

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ExpressionAtlasi
A5PLN7 baseline and differential

Genevisible search portal to normalized and curated expression data from Genevestigator

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Genevisiblei
A5PLN7 HS

Organism-specific databases

Human Protein Atlas

More...
HPAi
HPA044019
HPA055004

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

Protein-protein interaction databases

The Biological General Repository for Interaction Datasets (BioGrid)

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BioGridi
117378, 1 interactor

STRING: functional protein association networks

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STRINGi
9606.ENSP00000227065

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

3D structure databases

Protein Model Portal of the PSI-Nature Structural Biology Knowledgebase

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ProteinModelPortali
A5PLN7

Database of comparative protein structure models

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ModBasei
Search...

MobiDB: a database of protein disorder and mobility annotations

More...
MobiDBi
Search...

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Compositional bias

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Family and Domains’ section describes the position of regions of compositional bias within the protein and the particular amino acids that are over-represented within those regions.<p><a href='/help/compbias' target='_top'>More...</a></p>Compositional biasi34 – 37Poly-Ala4
Compositional biasi98 – 149Pro-richAdd BLAST52
Compositional biasi228 – 281Ser-richAdd BLAST54

<p>This subsection of the ‘Family and domains’ section provides information about the sequence similarity with other proteins.<p><a href='/help/sequence_similarities' target='_top'>More...</a></p>Sequence similaritiesi

Belongs to the FAM149 family.Curated

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

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eggNOGi
ENOG410IE96 Eukaryota
ENOG410ZYXN LUCA

Ensembl GeneTree

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GeneTreei
ENSGT00530000063727

The HOGENOM Database of Homologous Genes from Fully Sequenced Organisms

More...
HOGENOMi
HOG000112437

The HOVERGEN Database of Homologous Vertebrate Genes

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HOVERGENi
HBG107111

InParanoid: Eukaryotic Ortholog Groups

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InParanoidi
A5PLN7

Identification of Orthologs from Complete Genome Data

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OMAi
RPTYFAD

Database of Orthologous Groups

More...
OrthoDBi
538466at2759

Database for complete collections of gene phylogenies

More...
PhylomeDBi
A5PLN7

TreeFam database of animal gene trees

More...
TreeFami
TF330725

Family and domain databases

Integrated resource of protein families, domains and functional sites

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InterProi
View protein in InterPro
IPR022194 DUF3719
IPR039630 FAM149

The PANTHER Classification System

More...
PANTHERi
PTHR31997 PTHR31997, 1 hit

Pfam protein domain database

More...
Pfami
View protein in Pfam
PF12516 DUF3719, 1 hit

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence_length">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>.<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequences (4+)i

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences_section">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

This entry describes 4 <p>This subsection of the ‘Sequence’ section lists the alternative protein sequences (isoforms) that can be generated from the same gene by a single or by the combination of up to four biological events (alternative promoter usage, alternative splicing, alternative initiation and ribosomal frameshifting). Additionally, this section gives relevant information on each alternative protein isoform.<p><a href='/help/alternative_products' target='_top'>More...</a></p> isoformsi produced by alternative splicing. AlignAdd to basket

This entry has 4 described isoforms and 7 potential isoforms that are computationally mapped.Show allAlign All

Isoform 1 (identifier: A5PLN7-1) [UniParc]FASTAAdd to basket

This isoform has been chosen as the 'canonical' sequence. All positional information in this entry refers to it. This is also the sequence that appears in the downloadable versions of the entry.

« Hide
        10         20         30         40         50
MKAAVLDLGS LLAKLFETST APPAGPSSRP SGGAAAAGSG GSRAGTPLGT
60 70 80 90 100
APTLLRALAP DSPSASRRSP APLLSSPYSR GSAASRAAGA VGTLLSWPSS
110 120 130 140 150
PRAGKAPPQP PTPSGGGCSP ARLVVPARPP SGPGGVWAAL PRNPLQPGPG
160 170 180 190 200
ERELGACVAP GAGPRTLFLT LPDIGEEGAS DGDSGDGEAR GLSEGRRRHG
210 220 230 240 250
FTVRSKDSLP THFTRNVQKA IDKYTCKSLS SFSSSGSHTP TGAHTSWSGS
260 270 280 290 300
ATQSSTTGSS TERGSVYSWR DDEFDEASSQ SVQRLLWEVE EMLFEGKVNP
310 320 330 340 350
QTQSLLAECG EWTRRSLHLR VLGRQLILPT DKGVQHFQGS TPASAVHRPP
360 370 380 390 400
LSACGHSSNI RELCISGSQI VPAALSASAL PGPDDTGVAD LTARSSLEEE
410 420 430 440 450
VYHVDGKIEE YFAFDRKEDD DECLEQKPAQ PGRKWRKLGL PPVSPRDCVK
460 470 480 490 500
DAVAAEVFDH VWTNMVELLE ELIRKHWETT LTEGKKQRET LKVAGNRFPH
510 520 530 540 550
VLVPHAHADG ASGPPSGHAE AHGISLASRL NPPQIHHFSS SFYSDMNGVM
560 570 580 590 600
TIQAKPLQRR PAYFADRTQN EKEDKASGGG AGALSSAPHR LGRASDTHGL
610 620 630 640 650
SPSAKKTPVP WRLPSLASDS QRLKTPNIYS DEVLRGTKLP TGVDHMASPL
660 670 680 690 700
VQTSRSRFPP LVTETRGQNT AVPGCRLVSY RGRHLQNRVL SAMPDGTERS
710 720 730 740 750
RLRERTATLE RLSRPSTTHT FRQSDTPRKS SLTQMEFAAH TWTGQSILTG
760 770
SQYVPKSFQR TTLTFKRRFQ VTS
Length:773
Mass (Da):82,698
Last modified:February 26, 2008 - v2
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:i287183E70F1901E5
GO
Isoform 2 (identifier: A5PLN7-2) [UniParc]FASTAAdd to basket

The sequence of this isoform differs from the canonical sequence as follows:
     1-291: Missing.

Show »
Length:482
Mass (Da):53,250
Checksum:i7B976B1F92E4661C
GO
Isoform 3 (identifier: A5PLN7-3) [UniParc]FASTAAdd to basket

The sequence of this isoform differs from the canonical sequence as follows:
     723-723: Missing.

Show »
Length:772
Mass (Da):82,569
Checksum:iA82BA8F493E45281
GO
Isoform 4 (identifier: A5PLN7-4) [UniParc]FASTAAdd to basket

The sequence of this isoform differs from the canonical sequence as follows:
     227-235: Missing.

Note: No experimental confirmation available.
Show »
Length:764
Mass (Da):81,787
Checksum:i1F673FAE56038E4F
GO

<p>In eukaryotic reference proteomes, unreviewed entries that are likely to belong to the same gene are computationally mapped, based on gene identifiers from Ensembl, EnsemblGenomes and model organism databases.<p><a href='/help/gene_centric_isoform_mapping' target='_top'>More...</a></p>Computationally mapped potential isoform sequencesi

There are 7 potential isoforms mapped to this entry.BLASTAlignShow allAdd to basket
EntryEntry nameProtein names
Gene namesLengthAnnotation
A0A0A0MRZ3A0A0A0MRZ3_HUMAN
Protein FAM149A
FAM149A
402Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
D6RC92D6RC92_HUMAN
Protein FAM149A
FAM149A
76Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
D6RGX1D6RGX1_HUMAN
Protein FAM149A
FAM149A
36Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
H0Y965H0Y965_HUMAN
Protein FAM149A
FAM149A
147Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
H0Y909H0Y909_HUMAN
Protein FAM149A
FAM149A
159Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
D6RAL4D6RAL4_HUMAN
Protein FAM149A
FAM149A
61Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
H0Y8Y9H0Y8Y9_HUMAN
Protein FAM149A
FAM149A
53Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>

<p>This subsection of the ‘Sequence’ section reports difference(s) between the protein sequence shown in the UniProtKB entry and other available protein sequences derived from the same gene.<p><a href='/help/sequence_caution' target='_top'>More...</a></p>Sequence cautioni

The sequence AAI10817 differs from that shown. Reason: Erroneous initiation.Curated
The sequence AAQ13641 differs from that shown. Reason: Frameshift at position 635.Curated
The sequence AAQ13641 differs from that shown. Reason: Erroneous initiation. Translation N-terminally extended.Curated

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Sequence’ section reports difference(s) between the canonical sequence (displayed by default in the entry) and the different sequence submissions merged in the entry. These various submissions may originate from different sequencing projects, different types of experiments, or different biological samples. Sequence conflicts are usually of unknown origin.<p><a href='/help/conflict' target='_top'>More...</a></p>Sequence conflicti431P → L in CAB45695 (PubMed:17974005).Curated1
Sequence conflicti635R → G in AAQ13641 (Ref. 3) Curated1
Sequence conflicti644D → N in AAI42993 (PubMed:15489334).Curated1
Sequence conflicti730S → G in CAB45695 (PubMed:17974005).Curated1

Natural variant

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Sequence’ section describes natural variant(s) of the protein sequence.<p><a href='/help/variant' target='_top'>More...</a></p>Natural variantiVAR_039050332K → E1 PublicationCorresponds to variant dbSNP:rs4862650Ensembl.1
Natural variantiVAR_039051437K → E2 PublicationsCorresponds to variant dbSNP:rs4862653Ensembl.1
Natural variantiVAR_039052505H → R2 PublicationsCorresponds to variant dbSNP:rs2276924Ensembl.1
Natural variantiVAR_039053532P → L. Corresponds to variant dbSNP:rs2276922Ensembl.1
Natural variantiVAR_039054722R → W. Corresponds to variant dbSNP:rs9991339Ensembl.1
Natural variantiVAR_039055748L → V. Corresponds to variant dbSNP:rs6818265Ensembl.1

Alternative sequence

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Sequence’ section describes the sequence of naturally occurring alternative protein isoform(s). The changes in the amino acid sequence may be due to alternative splicing, alternative promoter usage, alternative initiation, or ribosomal frameshifting. The information stored in this subsection is used to automatically construct alternative protein sequence(s) for display.<p><a href='/help/var_seq' target='_top'>More...</a></p>Alternative sequenceiVSP_0315301 – 291Missing in isoform 2. 1 PublicationAdd BLAST291
Alternative sequenceiVSP_031531227 – 235Missing in isoform 4. Curated9
Alternative sequenceiVSP_031532723Missing in isoform 3. Curated1

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

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EMBLi

GenBank nucleotide sequence database

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GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...
DDBJi
Links Updated
AC104070 Genomic DNA No translation available.
AC110771 Genomic DNA No translation available.
BC110816 mRNA Translation: AAI10817.1 Different initiation.
BC142992 mRNA Translation: AAI42993.1
AF173894 mRNA Translation: AAQ13641.1 Sequence problems.
AL080065 mRNA Translation: CAB45695.2

The Consensus CDS (CCDS) project

More...
CCDSi
CCDS34117.1 [A5PLN7-2]

Protein sequence database of the Protein Information Resource

More...
PIRi
T12464

NCBI Reference Sequences

More...
RefSeqi
NP_001006656.1, NM_001006655.2 [A5PLN7-2]
NP_056213.1, NM_015398.2 [A5PLN7-2]
XP_016863486.1, XM_017007997.1
XP_016863491.1, XM_017008002.1
XP_016863492.1, XM_017008003.1
XP_016863493.1, XM_017008004.1
XP_016863494.1, XM_017008005.1

UniGene gene-oriented nucleotide sequence clusters

More...
UniGenei
Hs.744961

Genome annotation databases

Ensembl eukaryotic genome annotation project

More...
Ensembli
ENST00000227065; ENSP00000227065; ENSG00000109794 [A5PLN7-2]
ENST00000356371; ENSP00000348732; ENSG00000109794 [A5PLN7-1]
ENST00000502970; ENSP00000427155; ENSG00000109794 [A5PLN7-2]
ENST00000503432; ENSP00000426835; ENSG00000109794 [A5PLN7-2]
ENST00000514153; ENSP00000424380; ENSG00000109794 [A5PLN7-2]

Database of genes from NCBI RefSeq genomes

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GeneIDi
25854

KEGG: Kyoto Encyclopedia of Genes and Genomes

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KEGGi
hsa:25854

UCSC genome browser

More...
UCSCi
uc003iyt.5 human [A5PLN7-1]

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywords - Coding sequence diversityi

Alternative splicing, Polymorphism

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC104070 Genomic DNA No translation available.
AC110771 Genomic DNA No translation available.
BC110816 mRNA Translation: AAI10817.1 Different initiation.
BC142992 mRNA Translation: AAI42993.1
AF173894 mRNA Translation: AAQ13641.1 Sequence problems.
AL080065 mRNA Translation: CAB45695.2
CCDSiCCDS34117.1 [A5PLN7-2]
PIRiT12464
RefSeqiNP_001006656.1, NM_001006655.2 [A5PLN7-2]
NP_056213.1, NM_015398.2 [A5PLN7-2]
XP_016863486.1, XM_017007997.1
XP_016863491.1, XM_017008002.1
XP_016863492.1, XM_017008003.1
XP_016863493.1, XM_017008004.1
XP_016863494.1, XM_017008005.1
UniGeneiHs.744961

3D structure databases

ProteinModelPortaliA5PLN7
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

BioGridi117378, 1 interactor
STRINGi9606.ENSP00000227065

PTM databases

iPTMnetiA5PLN7
PhosphoSitePlusiA5PLN7

Polymorphism and mutation databases

BioMutaiFAM149A

Proteomic databases

jPOSTiA5PLN7
PaxDbiA5PLN7
PRIDEiA5PLN7
ProteomicsDBi740
741 [A5PLN7-2]
742 [A5PLN7-3]
743 [A5PLN7-4]

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENST00000227065; ENSP00000227065; ENSG00000109794 [A5PLN7-2]
ENST00000356371; ENSP00000348732; ENSG00000109794 [A5PLN7-1]
ENST00000502970; ENSP00000427155; ENSG00000109794 [A5PLN7-2]
ENST00000503432; ENSP00000426835; ENSG00000109794 [A5PLN7-2]
ENST00000514153; ENSP00000424380; ENSG00000109794 [A5PLN7-2]
GeneIDi25854
KEGGihsa:25854
UCSCiuc003iyt.5 human [A5PLN7-1]

Organism-specific databases

Comparative Toxicogenomics Database

More...
CTDi
25854
EuPathDBiHostDB:ENSG00000109794.13

GeneCards: human genes, protein and diseases

More...
GeneCardsi
FAM149A

H-Invitational Database, human transcriptome db

More...
H-InvDBi
HIX0031434
HGNCiHGNC:24527 FAM149A
HPAiHPA044019
HPA055004
neXtProtiNX_A5PLN7
OpenTargetsiENSG00000109794
PharmGKBiPA162386366

GenAtlas: human gene database

More...
GenAtlasi
Search...

Phylogenomic databases

eggNOGiENOG410IE96 Eukaryota
ENOG410ZYXN LUCA
GeneTreeiENSGT00530000063727
HOGENOMiHOG000112437
HOVERGENiHBG107111
InParanoidiA5PLN7
OMAiRPTYFAD
OrthoDBi538466at2759
PhylomeDBiA5PLN7
TreeFamiTF330725

Miscellaneous databases

ChiTaRS: a database of human, mouse and fruit fly chimeric transcripts and RNA-sequencing data

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ChiTaRSi
FAM149A human

Database of phenotypes from RNA interference screens in Drosophila and Homo sapiens

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GenomeRNAii
25854

Protein Ontology

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PROi
PR:A5PLN7

Gene expression databases

BgeeiENSG00000109794 Expressed in 205 organ(s), highest expression level in nucleus accumbens
CleanExiHS_FAM149A
ExpressionAtlasiA5PLN7 baseline and differential
GenevisibleiA5PLN7 HS

Family and domain databases

InterProiView protein in InterPro
IPR022194 DUF3719
IPR039630 FAM149
PANTHERiPTHR31997 PTHR31997, 1 hit
PfamiView protein in Pfam
PF12516 DUF3719, 1 hit

ProtoNet; Automatic hierarchical classification of proteins

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ProtoNeti
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<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the ‘Entry information’ section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiF149A_HUMAN
<p>This subsection of the ‘Entry information’ section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called ‘Primary (citable) accession number’.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: A5PLN7
Secondary accession number(s): B5MDB8
, Q2TAN6, Q7Z2S5, Q9Y4T9
<p>This subsection of the ‘Entry information’ section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification (‘Last modified’). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/Swiss-Prot: February 26, 2008
Last sequence update: February 26, 2008
Last modified: January 16, 2019
This is version 78 of the entry and version 2 of the sequence. See complete history.
<p>This subsection of the ‘Entry information’ section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

<p>This section contains any relevant information that doesn’t fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families
  2. Human entries with polymorphisms or disease mutations
    List of human entries with polymorphisms or disease mutations
  3. Human polymorphisms and disease mutations
    Index of human polymorphisms and disease mutations
  4. Human chromosome 4
    Human chromosome 4: entries, gene names and cross-references to MIM
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