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Entry version 99 (12 Aug 2020)
Sequence version 3 (05 Oct 2010)
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Protein

Ankyrin repeat domain-containing protein 34B

Gene

ANKRD34B

Organism
Homo sapiens (Human)
Status
Reviewed-Annotation score:

Annotation score:2 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Experimental evidence at transcript leveli <p>This indicates the type of evidence that supports the existence of the protein. Note that the 'protein existence' evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

Enzyme and pathway databases

Pathway Commons web resource for biological pathway data

More...
PathwayCommonsi
A5PLL1

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Recommended name:
Ankyrin repeat domain-containing protein 34B
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: 'Name', 'Synonyms', 'Ordered locus names' and 'ORF names'.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiHomo sapiens (Human)
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the 'taxonomic identifier' or 'taxid'.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri9606 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000005640 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes%5Fmanual">proteome</a> can consist of several components.<br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome 5

Organism-specific databases

Eukaryotic Pathogen Database Resources

More...
EuPathDBi
HostDB:ENSG00000189127.7

Human Gene Nomenclature Database

More...
HGNCi
HGNC:33736, ANKRD34B

Online Mendelian Inheritance in Man (OMIM)

More...
MIMi
618581, gene

neXtProt; the human protein knowledge platform

More...
neXtProti
NX_A5PLL1

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte & Seán O’Donoghue; Source: COMPARTMENTS

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywords - Cellular componenti

Cytoplasm, Nucleus

<p>This section provides information on the disease(s) and phenotype(s) associated with a protein.<p><a href='/help/pathology_and_biotech_section' target='_top'>More...</a></p>Pathology & Biotechi

Organism-specific databases

Open Targets

More...
OpenTargetsi
ENSG00000189127

The Pharmacogenetics and Pharmacogenomics Knowledge Base

More...
PharmGKBi
PA162376576

Miscellaneous databases

Pharos NIH Druggable Genome Knowledgebase

More...
Pharosi
A5PLL1, Tbio

Polymorphism and mutation databases

BioMuta curated single-nucleotide variation and disease association database

More...
BioMutai
ANKRD34B

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'PTM / Processing' section describes the extent of a polypeptide chain in the mature protein following processing or proteolytic cleavage.<p><a href='/help/chain' target='_top'>More...</a></p>ChainiPRO_00003191021 – 514Ankyrin repeat domain-containing protein 34BAdd BLAST514

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'PTM / Processing' section specifies the position and type of each modified residue excluding <a href="http://www.uniprot.org/manual/lipid">lipids</a>, <a href="http://www.uniprot.org/manual/carbohyd">glycans</a> and <a href="http://www.uniprot.org/manual/crosslnk">protein cross-links</a>.<p><a href='/help/mod_res' target='_top'>More...</a></p>Modified residuei263PhosphoserineBy similarity1
Modified residuei272PhosphothreonineBy similarity1
Modified residuei296PhosphoserineBy similarity1

<p>This subsection of the <a href="http://www.uniprot.org/help/ptm%5Fprocessing%5Fsection">PTM/processing</a> section describes post-translational modifications (PTMs). This subsection <strong>complements</strong> the information provided at the sequence level or describes modifications for which <strong>position-specific data is not yet available</strong>.<p><a href='/help/post-translational_modification' target='_top'>More...</a></p>Post-translational modificationi

Phosphorylated.By similarity

Keywords - PTMi

Phosphoprotein

Proteomic databases

Encyclopedia of Proteome Dynamics

More...
EPDi
A5PLL1

MassIVE - Mass Spectrometry Interactive Virtual Environment

More...
MassIVEi
A5PLL1

PaxDb, a database of protein abundance averages across all three domains of life

More...
PaxDbi
A5PLL1

PeptideAtlas

More...
PeptideAtlasi
A5PLL1

PRoteomics IDEntifications database

More...
PRIDEi
A5PLL1

ProteomicsDB: a multi-organism proteome resource

More...
ProteomicsDBi
737

PTM databases

iPTMnet integrated resource for PTMs in systems biology context

More...
iPTMneti
A5PLL1

Comprehensive resource for the study of protein post-translational modifications (PTMs) in human, mouse and rat.

More...
PhosphoSitePlusi
A5PLL1

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

Gene expression databases

Bgee dataBase for Gene Expression Evolution

More...
Bgeei
ENSG00000189127, Expressed in caudate nucleus and 52 other tissues

ExpressionAtlas, Differential and Baseline Expression

More...
ExpressionAtlasi
A5PLL1, baseline and differential

Organism-specific databases

Human Protein Atlas

More...
HPAi
ENSG00000189127, Tissue enriched (brain)

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

Protein-protein interaction databases

The Biological General Repository for Interaction Datasets (BioGRID)

More...
BioGRIDi
131001, 1 interactor

STRING: functional protein association networks

More...
STRINGi
9606.ENSP00000339802

Miscellaneous databases

RNAct, Protein-RNA interaction predictions for model organisms.

More...
RNActi
A5PLL1, protein

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

3D structure databases

SWISS-MODEL Repository - a database of annotated 3D protein structure models

More...
SMRi
A5PLL1

Database of comparative protein structure models

More...
ModBasei
Search...

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Family and Domains' section indicates the positions and types of repeated sequence motifs or repeated domains within the protein.<p><a href='/help/repeat' target='_top'>More...</a></p>Repeati9 – 38ANK 1Add BLAST30
Repeati42 – 79ANK 2Add BLAST38
Repeati83 – 113ANK 3Add BLAST31
Repeati117 – 146ANK 4Add BLAST30

<p>This subsection of the 'Family and domains' section provides information about the sequence similarity with other proteins.<p><a href='/help/sequence_similarities' target='_top'>More...</a></p>Sequence similaritiesi

Belongs to the ANKRD34 family.Curated

Keywords - Domaini

ANK repeat, Repeat

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

More...
eggNOGi
ENOG502QRZ2, Eukaryota

Ensembl GeneTree

More...
GeneTreei
ENSGT00390000012355

The HOGENOM Database of Homologous Genes from Fully Sequenced Organisms

More...
HOGENOMi
CLU_042805_0_0_1

InParanoid: Eukaryotic Ortholog Groups

More...
InParanoidi
A5PLL1

Identification of Orthologs from Complete Genome Data

More...
OMAi
SGRHTTK

Database of Orthologous Groups

More...
OrthoDBi
466691at2759

Database for complete collections of gene phylogenies

More...
PhylomeDBi
A5PLL1

TreeFam database of animal gene trees

More...
TreeFami
TF331155

Family and domain databases

Gene3D Structural and Functional Annotation of Protein Families

More...
Gene3Di
1.25.40.20, 1 hit

Integrated resource of protein families, domains and functional sites

More...
InterProi
View protein in InterPro
IPR042637, AN34A/B/C
IPR002110, Ankyrin_rpt
IPR020683, Ankyrin_rpt-contain_dom
IPR036770, Ankyrin_rpt-contain_sf

The PANTHER Classification System

More...
PANTHERi
PTHR24156, PTHR24156, 1 hit

Pfam protein domain database

More...
Pfami
View protein in Pfam
PF12796, Ank_2, 1 hit

Simple Modular Architecture Research Tool; a protein domain database

More...
SMARTi
View protein in SMART
SM00248, ANK, 4 hits

Superfamily database of structural and functional annotation

More...
SUPFAMi
SSF48403, SSF48403, 1 hit

PROSITE; a protein domain and family database

More...
PROSITEi
View protein in PROSITE
PS50297, ANK_REP_REGION, 1 hit
PS50088, ANK_REPEAT, 2 hits

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence%5Flength">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequence (1+)i

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences%5Fsection">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

This entry has 1 described isoform and 1 potential isoform that is computationally mapped.Show allAlign All

A5PLL1-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MDEGMEISSE GNSLIKAVHQ SRLRLTRLLL EGGAYINESN DRGETPLMIA
60 70 80 90 100
CKTKHVDHQS VSKAKMVKYL LENNADPNIQ DKSGKTALMH ACLEKAGPEV
110 120 130 140 150
VSLLLKSGAD LSLQDHSSYS ALVYAINSED TETLKVLLSA CKAKGKEVII
160 170 180 190 200
ITTAKLPCGK HTTKQYLNMP PVDIDGCHSP ATCTTPSEID IKTASSPLSH
210 220 230 240 250
SSETELTLFG FKDLELAGSN DDTWDPGSPV RKPALAPKGP KLPHAPPWVK
260 270 280 290 300
SPPLLMHQNR VASLQEELQD ITPEEELSYK TNGLALSKRF ITRHQSIDVK
310 320 330 340 350
DTAHLLRAFD QASSRKMSYD EINCQSYLSE GNQQCIEVPV DQDPDSNQTI
360 370 380 390 400
FASTLRSIVQ KRNLGANHYS SDSQLSAGLT PPTSEDGKAL IGKKKILSPS
410 420 430 440 450
PSQLSESKEL LENIPPGPLS RRNHAVLERR GSGAFPLDHS VTQTRQGFLP
460 470 480 490 500
PLNVNSHPPI SDINVNNKIC SLLSCGQKVL MPTVPIFPKE FKSKKMLLRR
510
QSLQTEQIKQ LVNF
Length:514
Mass (Da):56,414
Last modified:October 5, 2010 - v3
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:i65B1CC8F92E0730E
GO

<p>In eukaryotic reference proteomes, unreviewed entries that are likely to belong to the same gene are computationally mapped, based on gene identifiers from Ensembl, EnsemblGenomes and model organism databases.<p><a href='/help/gene_centric_isoform_mapping' target='_top'>More...</a></p>Computationally mapped potential isoform sequencesi

There is 1 potential isoform mapped to this entry.BLASTAlignShow allAdd to basket
EntryEntry nameProtein names
Gene namesLengthAnnotation
D6RH12D6RH12_HUMAN
Ankyrin repeat domain-containing pr...
ANKRD34B
17Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Sequence' section reports difference(s) between the canonical sequence (displayed by default in the entry) and the different sequence submissions merged in the entry. These various submissions may originate from different sequencing projects, different types of experiments, or different biological samples. Sequence conflicts are usually of unknown origin.<p><a href='/help/conflict' target='_top'>More...</a></p>Sequence conflicti429R → G in CAH18341 (PubMed:17974005).Curated1

Natural variant

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Sequence' section describes natural variant(s) of the protein sequence.<p><a href='/help/variant' target='_top'>More...</a></p>Natural variantiVAR_038952156L → S1 PublicationCorresponds to variant dbSNP:rs32857Ensembl.1

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...
EMBLi

GenBank nucleotide sequence database

More...
GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...
DDBJi
Links Updated
CR749535 mRNA Translation: CAH18341.1
AC008434 Genomic DNA No translation available.
BC137441 mRNA Translation: AAI37442.1
BC137442 mRNA Translation: AAI37443.1
BC142957 mRNA Translation: AAI42958.1

The Consensus CDS (CCDS) project

More...
CCDSi
CCDS34194.1

NCBI Reference Sequences

More...
RefSeqi
NP_001004441.2, NM_001004441.2
XP_006714662.1, XM_006714599.3
XP_011541668.1, XM_011543366.2
XP_011541671.1, XM_011543369.2

Genome annotation databases

Ensembl eukaryotic genome annotation project

More...
Ensembli
ENST00000338682; ENSP00000339802; ENSG00000189127

Database of genes from NCBI RefSeq genomes

More...
GeneIDi
340120

KEGG: Kyoto Encyclopedia of Genes and Genomes

More...
KEGGi
hsa:340120

UCSC genome browser

More...
UCSCi
uc003kgw.4, human

Keywords - Coding sequence diversityi

Polymorphism

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CR749535 mRNA Translation: CAH18341.1
AC008434 Genomic DNA No translation available.
BC137441 mRNA Translation: AAI37442.1
BC137442 mRNA Translation: AAI37443.1
BC142957 mRNA Translation: AAI42958.1
CCDSiCCDS34194.1
RefSeqiNP_001004441.2, NM_001004441.2
XP_006714662.1, XM_006714599.3
XP_011541668.1, XM_011543366.2
XP_011541671.1, XM_011543369.2

3D structure databases

SMRiA5PLL1
ModBaseiSearch...

Protein-protein interaction databases

BioGRIDi131001, 1 interactor
STRINGi9606.ENSP00000339802

PTM databases

iPTMnetiA5PLL1
PhosphoSitePlusiA5PLL1

Polymorphism and mutation databases

BioMutaiANKRD34B

Proteomic databases

EPDiA5PLL1
MassIVEiA5PLL1
PaxDbiA5PLL1
PeptideAtlasiA5PLL1
PRIDEiA5PLL1
ProteomicsDBi737

Protocols and materials databases

Antibodypedia a portal for validated antibodies

More...
Antibodypediai
49135, 80 antibodies

The DNASU plasmid repository

More...
DNASUi
340120

Genome annotation databases

EnsembliENST00000338682; ENSP00000339802; ENSG00000189127
GeneIDi340120
KEGGihsa:340120
UCSCiuc003kgw.4, human

Organism-specific databases

Comparative Toxicogenomics Database

More...
CTDi
340120
EuPathDBiHostDB:ENSG00000189127.7

GeneCards: human genes, protein and diseases

More...
GeneCardsi
ANKRD34B
HGNCiHGNC:33736, ANKRD34B
HPAiENSG00000189127, Tissue enriched (brain)
MIMi618581, gene
neXtProtiNX_A5PLL1
OpenTargetsiENSG00000189127
PharmGKBiPA162376576

GenAtlas: human gene database

More...
GenAtlasi
Search...

Phylogenomic databases

eggNOGiENOG502QRZ2, Eukaryota
GeneTreeiENSGT00390000012355
HOGENOMiCLU_042805_0_0_1
InParanoidiA5PLL1
OMAiSGRHTTK
OrthoDBi466691at2759
PhylomeDBiA5PLL1
TreeFamiTF331155

Enzyme and pathway databases

PathwayCommonsiA5PLL1

Miscellaneous databases

BioGRID ORCS database of CRISPR phenotype screens

More...
BioGRID-ORCSi
340120, 17 hits in 871 CRISPR screens

Database of phenotypes from RNA interference screens in Drosophila and Homo sapiens

More...
GenomeRNAii
340120
PharosiA5PLL1, Tbio

Protein Ontology

More...
PROi
PR:A5PLL1
RNActiA5PLL1, protein

The Stanford Online Universal Resource for Clones and ESTs

More...
SOURCEi
Search...

Gene expression databases

BgeeiENSG00000189127, Expressed in caudate nucleus and 52 other tissues
ExpressionAtlasiA5PLL1, baseline and differential

Family and domain databases

Gene3Di1.25.40.20, 1 hit
InterProiView protein in InterPro
IPR042637, AN34A/B/C
IPR002110, Ankyrin_rpt
IPR020683, Ankyrin_rpt-contain_dom
IPR036770, Ankyrin_rpt-contain_sf
PANTHERiPTHR24156, PTHR24156, 1 hit
PfamiView protein in Pfam
PF12796, Ank_2, 1 hit
SMARTiView protein in SMART
SM00248, ANK, 4 hits
SUPFAMiSSF48403, SSF48403, 1 hit
PROSITEiView protein in PROSITE
PS50297, ANK_REP_REGION, 1 hit
PS50088, ANK_REPEAT, 2 hits

ProtoNet; Automatic hierarchical classification of proteins

More...
ProtoNeti
Search...

MobiDB: a database of protein disorder and mobility annotations

More...
MobiDBi
Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the 'Entry information' section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiAN34B_HUMAN
<p>This subsection of the 'Entry information' section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called 'Primary (citable) accession number'.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: A5PLL1
Secondary accession number(s): B2RPH1, Q68D79
<p>This subsection of the 'Entry information' section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification ('Last modified'). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/Swiss-Prot: February 26, 2008
Last sequence update: October 5, 2010
Last modified: August 12, 2020
This is version 99 of the entry and version 3 of the sequence. See complete history.
<p>This subsection of the 'Entry information' section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

<p>This section contains any relevant information that doesn't fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Reference proteome

Documents

  1. Human polymorphisms and disease mutations
    Index of human polymorphisms and disease mutations
  2. MIM cross-references
    Online Mendelian Inheritance in Man (MIM) cross-references in UniProtKB/Swiss-Prot
  3. SIMILARITY comments
    Index of protein domains and families
  4. Human chromosome 5
    Human chromosome 5: entries, gene names and cross-references to MIM
  5. Human entries with polymorphisms or disease mutations
    List of human entries with polymorphisms or disease mutations
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