UniProtKB - A5PKY6 (A5PKY6_HUMAN)
Protein
Submitted name:
ABCC5 protein
Gene
ABCC5
Organism
Homo sapiens (Human)
Status
Functioni
GO - Molecular functioni
- ATPase-coupled transmembrane transporter activity Source: InterPro
- ATP binding Source: InterPro
- organic anion transmembrane transporter activity Source: InterPro
Names & Taxonomyi
Protein namesi | Submitted name: ABCC5 proteinImportedSubmitted name: Multidrug resistance-associated protein 5Imported |
Gene namesi | Name:ABCC5Imported |
Organismi | Homo sapiens (Human)Imported |
Taxonomic identifieri | 9606 [NCBI] |
Taxonomic lineagei | Eukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Mammalia › Eutheria › Euarchontoglires › Primates › Haplorrhini › Catarrhini › Hominidae › Homo |
Proteomesi |
|
Organism-specific databases
EuPathDBi | HostDB:ENSG00000114770.16 |
HGNCi | HGNC:56, ABCC5 |
Subcellular locationi
Other locations
- integral component of membrane Source: InterPro
Expressioni
Gene expression databases
Bgeei | ENSG00000114770, Expressed in forebrain and 238 other tissues |
Family & Domainsi
Region
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Regioni | 15 – 41 | DisorderedSequence analysisAdd BLAST | 27 |
Compositional bias
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Compositional biasi | 24 – 41 | PolyampholyteSequence analysisAdd BLAST | 18 |
Phylogenomic databases
GeneTreei | ENSGT00940000155470 |
Family and domain databases
InterProi | View protein in InterPro IPR030238, ABCC5 |
PANTHERi | PTHR24223:SF355, PTHR24223:SF355, 1 hit |
(1+)i Sequence
Sequence statusi: Complete.
This entry has 1 described isoform and 6 potential isoforms that are computationally mapped.Show allAlign All
A5PKY6-1 [UniParc]FASTAAdd to basket
10 20 30 40 50
MKDIDIGKEY IIPSPGYRSV RERTSTSGTH RDREDSKFRR TRPLECQDAL
60 70 80 90 100
ETAARAEGLS LDASMHSQLR ILDEEHPKGK YHHGLSALKP IRTTSKHQHP
110 120 130 140 150
VDNAGLFSCM TFSWLSSLAR VAHKKGELSM EDVWSLSKHE SSDVNCRRLE
160 170 180 190 200
RLWQEELNEV GPDAASLRRV VWIFCRTRLI LSIVCLMITQ LAGFSGPVSS
210 220 230
NHPFRQSPGA RPRPALTLLF CCRGCAQLWA R
Computationally mapped potential isoform sequencesi
There are 6 potential isoforms mapped to this entry.BLASTAlignShow allAdd to basketO15440 | MRP5_HUMAN | Multidrug resistance-associated pro... | ABCC5 MRP5 | 1,437 | Annotation score: | ||
F8WCY8 | F8WCY8_HUMAN | Multidrug resistance-associated pro... | ABCC5 | 473 | Annotation score: | ||
C9JZL5 | C9JZL5_HUMAN | Multidrug resistance-associated pro... | ABCC5 | 147 | Annotation score: | ||
E9PET4 | E9PET4_HUMAN | Multidrug resistance-associated pro... | ABCC5 | 53 | Annotation score: | ||
F8WDH3 | F8WDH3_HUMAN | Multidrug resistance-associated pro... | ABCC5 | 53 | Annotation score: | ||
H7C271 | H7C271_HUMAN | Multidrug resistance-associated pro... | ABCC5 | 70 | Annotation score: |
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | AC068644 Genomic DNA No translation available. BC142670 mRNA Translation: AAI42671.1 |
Genome annotation databases
Ensembli | ENST00000427120; ENSP00000404809; ENSG00000114770 |
UCSCi | uc010hxo.4, human |
Similar proteinsi
Cross-referencesi
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | AC068644 Genomic DNA No translation available. BC142670 mRNA Translation: AAI42671.1 |
3D structure databases
SMRi | A5PKY6 |
ModBasei | Search... |
Proteomic databases
MaxQBi | A5PKY6 |
PRIDEi | A5PKY6 |
ProteomicsDBi | 725 |
Protocols and materials databases
Antibodypediai | 18937, 389 antibodies |
Genome annotation databases
Ensembli | ENST00000427120; ENSP00000404809; ENSG00000114770 |
UCSCi | uc010hxo.4, human |
Organism-specific databases
EuPathDBi | HostDB:ENSG00000114770.16 |
HGNCi | HGNC:56, ABCC5 |
OpenTargetsi | ENSG00000114770 |
GenAtlasi | Search... |
Phylogenomic databases
GeneTreei | ENSGT00940000155470 |
Miscellaneous databases
ChiTaRSi | ABCC5, human |
Gene expression databases
Bgeei | ENSG00000114770, Expressed in forebrain and 238 other tissues |
Family and domain databases
InterProi | View protein in InterPro IPR030238, ABCC5 |
PANTHERi | PTHR24223:SF355, PTHR24223:SF355, 1 hit |
ProtoNeti | Search... |
MobiDBi | Search... |
Entry informationi
Entry namei | A5PKY6_HUMAN | |
Accessioni | A5PKY6Primary (citable) accession number: A5PKY6 | |
Entry historyi | Integrated into UniProtKB/TrEMBL: | July 10, 2007 |
Last sequence update: | July 10, 2007 | |
Last modified: | December 2, 2020 | |
This is version 101 of the entry and version 1 of the sequence. See complete history. | ||
Entry statusi | Unreviewed (UniProtKB/TrEMBL) | |
Disclaimer | Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care. |