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Protein
Submitted name:

TPCN1 protein

Gene

TPCN1

Organism
Homo sapiens (Human)
Status
Unreviewed-Annotation score: -Experimental evidence at transcript leveli

Functioni

GO - Molecular functioni

Names & Taxonomyi

Protein namesi
Submitted name:
TPCN1 proteinImported
Gene namesi
Name:TPCN1Imported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo

Subcellular locationi

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Transmembranei107 – 129HelicalSequence analysisAdd BLAST23
Transmembranei135 – 156HelicalSequence analysisAdd BLAST22
Transmembranei177 – 195HelicalSequence analysisAdd BLAST19
Transmembranei235 – 254HelicalSequence analysisAdd BLAST20
Transmembranei261 – 280HelicalSequence analysisAdd BLAST20
Transmembranei300 – 323HelicalSequence analysisAdd BLAST24
Transmembranei445 – 465HelicalSequence analysisAdd BLAST21
Transmembranei477 – 495HelicalSequence analysisAdd BLAST19

Keywords - Cellular componenti

Membrane

PTM / Processingi

Proteomic databases

MaxQBiA5PKY2
PeptideAtlasiA5PKY2
PRIDEiA5PKY2

Structurei

3D structure databases

ProteinModelPortaliA5PKY2
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini108 – 330Ion_transInterPro annotationAdd BLAST223
Domaini441 – 570Ion_transInterPro annotationAdd BLAST130

Keywords - Domaini

Transmembrane, Transmembrane helixSequence analysisSAAS annotation

Phylogenomic databases

eggNOGiENOG410INF7 Eukaryota
ENOG410XZT8 LUCA
HOVERGENiHBG080605

Family and domain databases

Gene3Di1.20.120.350, 1 hit
InterProiView protein in InterPro
IPR005821 Ion_trans_dom
IPR028801 TPC1
IPR027359 Volt_channel_dom_sf
PANTHERiPTHR10037:SF231 PTHR10037:SF231, 1 hit
PfamiView protein in Pfam
PF00520 Ion_trans, 2 hits

Sequencei

Sequence statusi: Complete.

A5PKY2-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MAVSLDDDVP LILTLDEGGS APLAPSNGLG QEELPSKNGG SYAIHDSQAP
60 70 80 90 100
SLSSGGESSP SSPAHNWEMN YQEAAIYLQE GENNDKFFTH PKDAKALAAY
110 120 130 140 150
LFAHNHLFYL MELATALLLL LLSLCEAPAV PALRLGIYVH ATLELFALMV
160 170 180 190 200
VVFELCMKLR WLGLHTFIRH KRTMVKTSVL VVQFVEAIVV LVRQMSHVRV
210 220 230 240 250
TRALRCIFLV DCRYCGGVRR NLRQIFQSLP PFMDILLLLL FFMIIFAILG
260 270 280 290 300
FYLFSPNPSD PYFSTLENSI VSLFVLLTTA NFPDVMMPSY SRNPWSCVFF
310 320 330 340 350
IVYLSIELYF IMNLLLAVVF DTFNDIEKRK FKSLLLHKRT AIQHAYRLLI
360 370 380 390 400
SQRRPAGISY RQFEGLMRFY KPRMSARERY LTFKALNQNN TPLLSLKDFY
410 420 430 440 450
DIYEVAALKW KAKKNREHWF DELPRTALLI FKGINILVKS KAFQYFMYLV
460 470 480 490 500
VAVNGVWILV ETFMLKGGNF FSKHVPWSYL VFLTIYGVEL FLKVAGLGPV
510 520 530 540 550
EYLSSGWNLF DFSVTVFAFL GLLALALNME PFYFIVVLRP LQLLRLFKLK
560 570 580 590 600
ERYRNVLDTM FELLPRMARY CQPPPWPAGP GAVWQCPVGA GAEWQSGERS
610
STKDCNRGPD GAPRSLES
Length:618
Mass (Da):70,575
Last modified:July 10, 2007 - v1
Checksum:i56D4FA83A929FDCE
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BC142664 mRNA Translation: AAI42665.1
UniGeneiHs.524763

Similar proteinsi

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BC142664 mRNA Translation: AAI42665.1
UniGeneiHs.524763

3D structure databases

ProteinModelPortaliA5PKY2
ModBaseiSearch...
MobiDBiSearch...

Proteomic databases

MaxQBiA5PKY2
PeptideAtlasiA5PKY2
PRIDEiA5PKY2

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Phylogenomic databases

eggNOGiENOG410INF7 Eukaryota
ENOG410XZT8 LUCA
HOVERGENiHBG080605

Miscellaneous databases

ChiTaRSiTPCN1 human

Family and domain databases

Gene3Di1.20.120.350, 1 hit
InterProiView protein in InterPro
IPR005821 Ion_trans_dom
IPR028801 TPC1
IPR027359 Volt_channel_dom_sf
PANTHERiPTHR10037:SF231 PTHR10037:SF231, 1 hit
PfamiView protein in Pfam
PF00520 Ion_trans, 2 hits
ProtoNetiSearch...

Entry informationi

Entry nameiA5PKY2_HUMAN
AccessioniPrimary (citable) accession number: A5PKY2
Entry historyiIntegrated into UniProtKB/TrEMBL: July 10, 2007
Last sequence update: July 10, 2007
Last modified: February 28, 2018
This is version 68 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health

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