UniProtKB - A5PJA6 (A5PJA6_BOVIN)
Protein
Submitted name:
Stomatin (EPB72)-like 2
Gene
STOML2
Organism
Bos taurus (Bovine)
Status
Functioni
GO - Molecular functioni
- cardiolipin binding Source: Ensembl
- GTPase binding Source: Ensembl
GO - Biological processi
- CD4-positive, alpha-beta T cell activation Source: Ensembl
- cellular calcium ion homeostasis Source: Ensembl
- interleukin-2 production Source: Ensembl
- lipid localization Source: Ensembl
- mitochondrial ATP synthesis coupled proton transport Source: Ensembl
- mitochondrial calcium ion transmembrane transport Source: Ensembl
- mitochondrial protein processing Source: Ensembl
- positive regulation of cardiolipin metabolic process Source: Ensembl
- positive regulation of mitochondrial DNA replication Source: Ensembl
- positive regulation of mitochondrial membrane potential Source: Ensembl
- protein complex oligomerization Source: Ensembl
- stress-induced mitochondrial fusion Source: Ensembl
- T cell receptor signaling pathway Source: Ensembl
Names & Taxonomyi
Protein namesi | Submitted name: Stomatin (EPB72)-like 2ImportedSubmitted name: Stomatin-like protein 2, mitochondrialImported |
Gene namesi | Name:STOML2Imported |
Organismi | Bos taurus (Bovine)Imported |
Taxonomic identifieri | 9913 [NCBI] |
Taxonomic lineagei | Eukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Mammalia › Eutheria › Laurasiatheria › Artiodactyla › Ruminantia › Pecora › Bovidae › Bovinae › Bos |
Proteomesi |
|
Organism-specific databases
VGNCi | VGNC:35411, STOML2 |
Subcellular locationi
Cytoskeleton
- actin cytoskeleton Source: Ensembl
Mitochondrion
- mitochondrial inner membrane Source: Ensembl
- mitochondrial intermembrane space Source: Ensembl
Nucleus
- COP9 signalosome Source: Ensembl
Plasma Membrane
- extrinsic component of plasma membrane Source: Ensembl
- immunological synapse Source: Ensembl
- T cell receptor complex Source: Ensembl
Other locations
- membrane raft Source: Ensembl
Expressioni
Gene expression databases
Bgeei | ENSBTAG00000011388, Expressed in skeletal muscle tissue and 18 other tissues |
Family & Domainsi
Domains and Repeats
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Domaini | 36 – 194 | PHBInterPro annotationAdd BLAST | 159 |
Region
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Regioni | 326 – 356 | DisorderedSequence analysisAdd BLAST | 31 |
Compositional bias
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Compositional biasi | 340 – 356 | PolyampholyteSequence analysisAdd BLAST | 17 |
Sequence similaritiesi
Belongs to the band 7/mec-2 family.ARBA annotation
Phylogenomic databases
GeneTreei | ENSGT01010000222507 |
HOGENOMi | CLU_024949_1_0_1 |
OMAi | YLQMLPK |
TreeFami | TF105750 |
Family and domain databases
InterProi | View protein in InterPro IPR001107, Band_7 IPR036013, Band_7/SPFH_dom_sf IPR032435, Band_7_C IPR001972, Stomatin_HflK_HflKC_fam |
Pfami | View protein in Pfam PF01145, Band_7, 1 hit PF16200, Band_7_C, 1 hit |
PRINTSi | PR00721, STOMATIN |
SMARTi | View protein in SMART SM00244, PHB, 1 hit |
SUPFAMi | SSF117892, SSF117892, 1 hit |
i Sequence
Sequence statusi: Complete.
A5PJA6-1 [UniParc]FASTAAdd to basket
10 20 30 40 50
MLARAARGTG ALLLKGSVQA SARAPRRASS GLPRNTVVLF VPQQEAWVVE
60 70 80 90 100
RMGRFHRILE PGLNILIPVL DRIRYVQSLK EIVINVPEQS AVTLDNVTLQ
110 120 130 140 150
IDGVLYLRIM DPYKASYGVE DPEYAVTQLA QTTMRSELGK LSLDKVFRER
160 170 180 190 200
ESLNASIVDA INQAADCWGI RCLRYEIKDI HVPPRVKESM QMQVEAERRK
210 220 230 240 250
RATVLESEGT RESAINVAEG KKQAQILASE AEKAEQINQA AGEASAVLAK
260 270 280 290 300
AKAKAEAIRI LAAALTQHNG DAAASLTVAE QYVSAFSKLA KDSNTILLPS
310 320 330 340 350
NPGDVTSMVA QAMGVYGALT KAPIPEAQDS VSSRSSRDVR STDASLDEEL
DRVKLS
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | BC142027 mRNA Translation: AAI42028.1 |
Genome annotation databases
Ensembli | ENSBTAT00000015136; ENSBTAP00000015136; ENSBTAG00000011388 |
Similar proteinsi
Cross-referencesi
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | BC142027 mRNA Translation: AAI42028.1 |
3D structure databases
ModBasei | Search... |
SWISS-MODEL-Workspacei | Submit a new modelling project... |
Genome annotation databases
Ensembli | ENSBTAT00000015136; ENSBTAP00000015136; ENSBTAG00000011388 |
Organism-specific databases
VGNCi | VGNC:35411, STOML2 |
Phylogenomic databases
GeneTreei | ENSGT01010000222507 |
HOGENOMi | CLU_024949_1_0_1 |
OMAi | YLQMLPK |
TreeFami | TF105750 |
Gene expression databases
Bgeei | ENSBTAG00000011388, Expressed in skeletal muscle tissue and 18 other tissues |
Family and domain databases
InterProi | View protein in InterPro IPR001107, Band_7 IPR036013, Band_7/SPFH_dom_sf IPR032435, Band_7_C IPR001972, Stomatin_HflK_HflKC_fam |
Pfami | View protein in Pfam PF01145, Band_7, 1 hit PF16200, Band_7_C, 1 hit |
PRINTSi | PR00721, STOMATIN |
SMARTi | View protein in SMART SM00244, PHB, 1 hit |
SUPFAMi | SSF117892, SSF117892, 1 hit |
ProtoNeti | Search... |
MobiDBi | Search... |
Entry informationi
Entry namei | A5PJA6_BOVIN | |
Accessioni | A5PJA6Primary (citable) accession number: A5PJA6 | |
Entry historyi | Integrated into UniProtKB/TrEMBL: | July 10, 2007 |
Last sequence update: | July 10, 2007 | |
Last modified: | December 2, 2020 | |
This is version 88 of the entry and version 1 of the sequence. See complete history. | ||
Entry statusi | Unreviewed (UniProtKB/TrEMBL) |