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Entry version 104 (16 Oct 2019)
Sequence version 1 (12 Jun 2007)
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Protein

Coiled-coil domain-containing protein 151

Gene

CCDC151

Organism
Homo sapiens (Human)
Status
Reviewed-Annotation score:

Annotation score:5 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Experimental evidence at protein leveli <p>This indicates the type of evidence that supports the existence of the protein. Note that the ‘protein existence’ evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

Ciliary protein involved in outer dynein arm assembly and required for motile cilia function.By similarity

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Biological processi

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywordsi

Biological processCilium biogenesis/degradation

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Recommended name:
Coiled-coil domain-containing protein 151
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: ‘Name’, ‘Synonyms’, ‘Ordered locus names’ and ‘ORF names’.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:CCDC151
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiHomo sapiens (Human)
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the ‘taxonomic identifier’ or ‘taxid’.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri9606 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000005640 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes_manual">proteome</a> can consist of several components. <br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome 19

Organism-specific databases

Human Gene Nomenclature Database

More...
HGNCi
HGNC:28303 CCDC151

Online Mendelian Inheritance in Man (OMIM)

More...
MIMi
615956 gene

neXtProt; the human protein knowledge platform

More...
neXtProti
NX_A5D8V7

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte & Seán O’Donoghue; Source: COMPARTMENTS

Keywords - Cellular componenti

Cell projection, Cytoplasm, Cytoskeleton

<p>This section provides information on the disease(s) and phenotype(s) associated with a protein.<p><a href='/help/pathology_and_biotech_section' target='_top'>More...</a></p>Pathology & Biotechi

<p>This subsection of the ‘Pathology and Biotech’ section provides information on the disease(s) associated with genetic variations in a given protein. The information is extracted from the scientific literature and diseases that are also described in the <a href="http://www.ncbi.nlm.nih.gov/sites/entrez?db=omim">OMIM</a> database are represented with a <a href="http://www.uniprot.org/diseases">controlled vocabulary</a> in the following way:<p><a href='/help/involvement_in_disease' target='_top'>More...</a></p>Involvement in diseasei

Ciliary dyskinesia, primary, 30 (CILD30)2 Publications
The disease is caused by mutations affecting the gene represented in this entry.
Disease descriptionA disorder characterized by abnormalities of motile cilia. Respiratory infections leading to chronic inflammation and bronchiectasis are recurrent, due to defects in the respiratory cilia. Patients may exhibit randomization of left-right body asymmetry and situs inversus, due to dysfunction of monocilia at the embryonic node. Primary ciliary dyskinesia associated with situs inversus is referred to as Kartagener syndrome.
Related information in OMIM

Keywords - Diseasei

Ciliopathy, Kartagener syndrome, Primary ciliary dyskinesia

Organism-specific databases

DisGeNET

More...
DisGeNETi
115948

GeneReviews a resource of expert-authored, peer-reviewed disease descriptions.

More...
GeneReviewsi
CCDC151

MalaCards human disease database

More...
MalaCardsi
CCDC151
MIMi616037 phenotype

Open Targets

More...
OpenTargetsi
ENSG00000198003

Orphanet; a database dedicated to information on rare diseases and orphan drugs

More...
Orphaneti
244 Primary ciliary dyskinesia

The Pharmacogenetics and Pharmacogenomics Knowledge Base

More...
PharmGKBi
PA162381584

Miscellaneous databases

Pharos NIH Druggable Genome Knowledgebase

More...
Pharosi
A5D8V7

Polymorphism and mutation databases

BioMuta curated single-nucleotide variation and disease association database

More...
BioMutai
CCDC151

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘PTM / Processing’ section describes the extent of a polypeptide chain in the mature protein following processing.<p><a href='/help/chain' target='_top'>More...</a></p>ChainiPRO_00003215261 – 595Coiled-coil domain-containing protein 151Add BLAST595

Proteomic databases

Encyclopedia of Proteome Dynamics

More...
EPDi
A5D8V7

jPOST - Japan Proteome Standard Repository/Database

More...
jPOSTi
A5D8V7

MassIVE - Mass Spectrometry Interactive Virtual Environment

More...
MassIVEi
A5D8V7

MaxQB - The MaxQuant DataBase

More...
MaxQBi
A5D8V7

PaxDb, a database of protein abundance averages across all three domains of life

More...
PaxDbi
A5D8V7

PRoteomics IDEntifications database

More...
PRIDEi
A5D8V7

ProteomicsDB: a multi-organism proteome resource

More...
ProteomicsDBi
5469
713 [A5D8V7-1]

PTM databases

iPTMnet integrated resource for PTMs in systems biology context

More...
iPTMneti
A5D8V7

Comprehensive resource for the study of protein post-translational modifications (PTMs) in human, mouse and rat.

More...
PhosphoSitePlusi
A5D8V7

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

Gene expression databases

Bgee dataBase for Gene Expression Evolution

More...
Bgeei
ENSG00000198003 Expressed in 134 organ(s), highest expression level in bronchial epithelial cell

ExpressionAtlas, Differential and Baseline Expression

More...
ExpressionAtlasi
A5D8V7 baseline and differential

Genevisible search portal to normalized and curated expression data from Genevestigator

More...
Genevisiblei
A5D8V7 HS

Organism-specific databases

Human Protein Atlas

More...
HPAi
HPA044184
HPA054626

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

<p>This subsection of the <a href="http://www.uniprot.org/help/interaction_section">'Interaction'</a> section provides information about the protein quaternary structure and interaction(s) with other proteins or protein complexes (with the exception of physiological receptor-ligand interactions which are annotated in the <a href="http://www.uniprot.org/help/function_section">'Function'</a> section).<p><a href='/help/subunit_structure' target='_top'>More...</a></p>Subunit structurei

Interacts with CCDC114.

1 Publication

<p>This subsection of the '<a href="http://www.uniprot.org/help/interaction_section%27">Interaction</a> section provides information about binary protein-protein interactions. The data presented in this section are a quality-filtered subset of binary interactions automatically derived from the <a href="http://www.ebi.ac.uk/intact/">IntAct database</a>. It is updated on a monthly basis. Each binary interaction is displayed on a separate line.<p><a href='/help/binary_interactions' target='_top'>More...</a></p>Binary interactionsi

Protein-protein interaction databases

The Biological General Repository for Interaction Datasets (BioGrid)

More...
BioGridi
125463, 30 interactors

Protein interaction database and analysis system

More...
IntActi
A5D8V7, 31 interactors

Molecular INTeraction database

More...
MINTi
A5D8V7

STRING: functional protein association networks

More...
STRINGi
9606.ENSP00000348757

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

3D structure databases

SWISS-MODEL Repository - a database of annotated 3D protein structure models

More...
SMRi
A5D8V7

Database of comparative protein structure models

More...
ModBasei
Search...

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Coiled coil

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Family and domains’ section denotes the positions of regions of coiled coil within the protein.<p><a href='/help/coiled' target='_top'>More...</a></p>Coiled coili94 – 327Sequence analysisAdd BLAST234
Coiled coili385 – 473Sequence analysisAdd BLAST89

Keywords - Domaini

Coiled coil

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

More...
eggNOGi
ENOG410IFZ0 Eukaryota
ENOG410ZD3T LUCA

Ensembl GeneTree

More...
GeneTreei
ENSGT00940000153116

The HOGENOM Database of Homologous Genes from Fully Sequenced Organisms

More...
HOGENOMi
HOG000007822

InParanoid: Eukaryotic Ortholog Groups

More...
InParanoidi
A5D8V7

Identification of Orthologs from Complete Genome Data

More...
OMAi
DSNTEMA

Database of Orthologous Groups

More...
OrthoDBi
969618at2759

Database for complete collections of gene phylogenies

More...
PhylomeDBi
A5D8V7

TreeFam database of animal gene trees

More...
TreeFami
TF324955

Family and domain databases

Integrated resource of protein families, domains and functional sites

More...
InterProi
View protein in InterPro
IPR033192 CCDC151

The PANTHER Classification System

More...
PANTHERi
PTHR46518 PTHR46518, 1 hit

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence_length">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequences (2+)i

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences_section">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

This entry describes 2 <p>This subsection of the ‘Sequence’ section lists the alternative protein sequences (isoforms) that can be generated from the same gene by a single or by the combination of up to four biological events (alternative promoter usage, alternative splicing, alternative initiation and ribosomal frameshifting). Additionally, this section gives relevant information on each alternative protein isoform.<p><a href='/help/alternative_products' target='_top'>More...</a></p> isoformsi produced by alternative splicing. AlignAdd to basket

This entry has 2 described isoforms and 3 potential isoforms that are computationally mapped.Show allAlign All

Isoform 1 (identifier: A5D8V7-1) [UniParc]FASTAAdd to basket

This isoform has been chosen as the <div> <p><b>What is the canonical sequence?</b><p><a href='/help/canonical_and_isoforms' target='_top'>More...</a></p>canonicali sequence. All positional information in this entry refers to it. This is also the sequence that appears in the downloadable versions of the entry.

« Hide
        10         20         30         40         50
MTSPLCRAAS ANALPPQDQA STPSSRVKGR EASGKPSHLR GKGTAQAWTP
60 70 80 90 100
GRSKGGSFHR GAGKPSVHSQ VAELHKKIQL LEGDRKAFFE SSQWNIKKNQ
110 120 130 140 150
ETISQLRKET KALELKLLDL LKGDEKVVQA VIREWKWEKP YLKNRTGQAL
160 170 180 190 200
EHLDHRLREK VKQQNALRHQ VVLRQRRLEE LQLQHSLRLL EMAEAQNRHT
210 220 230 240 250
EVAKTMRNLE NRLEKAQMKA QEAEHITSVY LQLKAYLMDE SLNLENRLDS
260 270 280 290 300
MEAEVVRTKH ELEALHVVNQ EALNARDIAK NQLQYLEETL VRERKKRERY
310 320 330 340 350
ISECKKRAEE KKLENERMER KTHREHLLLQ SDDTIQDSLH AKEEELRQRW
360 370 380 390 400
SMYQMEVIFG KVKDATGTDE THSLVRRFLA QGDTFAQLET LKSENEQTLV
410 420 430 440 450
RLKQEKQQLQ RELEDLKYSG EATLVSQQKL QAEAQERLKK EERRHAEAKD
460 470 480 490 500
QLERALRAMQ VAKDSLEHLA SKLIHITVED GRFAGKELDP QADNYVPNLL
510 520 530 540 550
GLVEEKLLKL QAQLQGHDVQ EMLCHIANRE FLASLEGRLP EYNTRIALPL
560 570 580 590
ATSKDKFFDE ESEEEDNEVV TRASLKIRSQ KLIESHKKHR RSRRS
Length:595
Mass (Da):69,140
Last modified:June 12, 2007 - v1
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:iE0DA463B2F340D0E
GO
Isoform 2 (identifier: A5D8V7-2) [UniParc]FASTAAdd to basket

The sequence of this isoform differs from the canonical sequence as follows:
     1-81: MTSPLCRAAS...AELHKKIQLL → MHPPVAPCKKLRCPPTRSFTPTRGRSK

Note: No experimental confirmation available.
Show »
Length:541
Mass (Da):63,737
Checksum:i74E3B92EE5F5E97F
GO

<p>In eukaryotic reference proteomes, unreviewed entries that are likely to belong to the same gene are computationally mapped, based on gene identifiers from Ensembl, EnsemblGenomes and model organism databases.<p><a href='/help/gene_centric_isoform_mapping' target='_top'>More...</a></p>Computationally mapped potential isoform sequencesi

There are 3 potential isoforms mapped to this entry.BLASTAlignShow allAdd to basket
EntryEntry nameProtein names
Gene namesLengthAnnotation
K7EN59K7EN59_HUMAN
Coiled-coil domain-containing prote...
CCDC151
535Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
K7EPK8K7EPK8_HUMAN
Coiled-coil domain-containing prote...
CCDC151
404Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
K7EPB4K7EPB4_HUMAN
Coiled-coil domain-containing prote...
CCDC151
115Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Sequence’ section reports difference(s) between the canonical sequence (displayed by default in the entry) and the different sequence submissions merged in the entry. These various submissions may originate from different sequencing projects, different types of experiments, or different biological samples. Sequence conflicts are usually of unknown origin.<p><a href='/help/conflict' target='_top'>More...</a></p>Sequence conflicti470A → S in AAH14252 (PubMed:15489334).Curated1

Natural variant

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Sequence’ section describes natural variant(s) of the protein sequence.<p><a href='/help/variant' target='_top'>More...</a></p>Natural variantiVAR_050743545R → P. Corresponds to variant dbSNP:rs34619515Ensembl.1

Alternative sequence

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Sequence’ section describes the sequence of naturally occurring alternative protein isoform(s). The changes in the amino acid sequence may be due to alternative splicing, alternative promoter usage, alternative initiation, or ribosomal frameshifting.<p><a href='/help/var_seq' target='_top'>More...</a></p>Alternative sequenceiVSP_0569031 – 81MTSPL…KIQLL → MHPPVAPCKKLRCPPTRSFT PTRGRSK in isoform 2. 1 PublicationAdd BLAST81

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...
EMBLi

GenBank nucleotide sequence database

More...
GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...
DDBJi
Links Updated
AK302113 mRNA Translation: BAG63492.1
AC024575 Genomic DNA No translation available.
CH471106 Genomic DNA Translation: EAW84213.1
BC014252 mRNA Translation: AAH14252.2
BC141828 mRNA Translation: AAI41829.1
BC142637 mRNA Translation: AAI42638.1

The Consensus CDS (CCDS) project

More...
CCDSi
CCDS42501.1 [A5D8V7-1]

NCBI Reference Sequences

More...
RefSeqi
NP_001289382.1, NM_001302453.1 [A5D8V7-2]
NP_659482.3, NM_145045.4 [A5D8V7-1]

Genome annotation databases

Ensembl eukaryotic genome annotation project

More...
Ensembli
ENST00000356392; ENSP00000348757; ENSG00000198003 [A5D8V7-1]

Database of genes from NCBI RefSeq genomes

More...
GeneIDi
115948

KEGG: Kyoto Encyclopedia of Genes and Genomes

More...
KEGGi
hsa:115948

UCSC genome browser

More...
UCSCi
uc002mrs.5 human [A5D8V7-1]

Keywords - Coding sequence diversityi

Alternative splicing, Polymorphism

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AK302113 mRNA Translation: BAG63492.1
AC024575 Genomic DNA No translation available.
CH471106 Genomic DNA Translation: EAW84213.1
BC014252 mRNA Translation: AAH14252.2
BC141828 mRNA Translation: AAI41829.1
BC142637 mRNA Translation: AAI42638.1
CCDSiCCDS42501.1 [A5D8V7-1]
RefSeqiNP_001289382.1, NM_001302453.1 [A5D8V7-2]
NP_659482.3, NM_145045.4 [A5D8V7-1]

3D structure databases

SMRiA5D8V7
ModBaseiSearch...

Protein-protein interaction databases

BioGridi125463, 30 interactors
IntActiA5D8V7, 31 interactors
MINTiA5D8V7
STRINGi9606.ENSP00000348757

PTM databases

iPTMnetiA5D8V7
PhosphoSitePlusiA5D8V7

Polymorphism and mutation databases

BioMutaiCCDC151

Proteomic databases

EPDiA5D8V7
jPOSTiA5D8V7
MassIVEiA5D8V7
MaxQBiA5D8V7
PaxDbiA5D8V7
PRIDEiA5D8V7
ProteomicsDBi5469
713 [A5D8V7-1]

Genome annotation databases

EnsembliENST00000356392; ENSP00000348757; ENSG00000198003 [A5D8V7-1]
GeneIDi115948
KEGGihsa:115948
UCSCiuc002mrs.5 human [A5D8V7-1]

Organism-specific databases

Comparative Toxicogenomics Database

More...
CTDi
115948
DisGeNETi115948

GeneCards: human genes, protein and diseases

More...
GeneCardsi
CCDC151
GeneReviewsiCCDC151
HGNCiHGNC:28303 CCDC151
HPAiHPA044184
HPA054626
MalaCardsiCCDC151
MIMi615956 gene
616037 phenotype
neXtProtiNX_A5D8V7
OpenTargetsiENSG00000198003
Orphaneti244 Primary ciliary dyskinesia
PharmGKBiPA162381584

GenAtlas: human gene database

More...
GenAtlasi
Search...

Phylogenomic databases

eggNOGiENOG410IFZ0 Eukaryota
ENOG410ZD3T LUCA
GeneTreeiENSGT00940000153116
HOGENOMiHOG000007822
InParanoidiA5D8V7
OMAiDSNTEMA
OrthoDBi969618at2759
PhylomeDBiA5D8V7
TreeFamiTF324955

Miscellaneous databases

ChiTaRS: a database of human, mouse and fruit fly chimeric transcripts and RNA-sequencing data

More...
ChiTaRSi
CCDC151 human

Database of phenotypes from RNA interference screens in Drosophila and Homo sapiens

More...
GenomeRNAii
115948
PharosiA5D8V7

Protein Ontology

More...
PROi
PR:A5D8V7

The Stanford Online Universal Resource for Clones and ESTs

More...
SOURCEi
Search...

Gene expression databases

BgeeiENSG00000198003 Expressed in 134 organ(s), highest expression level in bronchial epithelial cell
ExpressionAtlasiA5D8V7 baseline and differential
GenevisibleiA5D8V7 HS

Family and domain databases

InterProiView protein in InterPro
IPR033192 CCDC151
PANTHERiPTHR46518 PTHR46518, 1 hit

ProtoNet; Automatic hierarchical classification of proteins

More...
ProtoNeti
Search...

MobiDB: a database of protein disorder and mobility annotations

More...
MobiDBi
Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the ‘Entry information’ section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiCC151_HUMAN
<p>This subsection of the ‘Entry information’ section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called ‘Primary (citable) accession number’.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: A5D8V7
Secondary accession number(s): B4DXT0, Q96CG5
<p>This subsection of the ‘Entry information’ section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification (‘Last modified’). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/Swiss-Prot: February 26, 2008
Last sequence update: June 12, 2007
Last modified: October 16, 2019
This is version 104 of the entry and version 1 of the sequence. See complete history.
<p>This subsection of the ‘Entry information’ section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

<p>This section contains any relevant information that doesn’t fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Human polymorphisms and disease mutations
    Index of human polymorphisms and disease mutations
  2. MIM cross-references
    Online Mendelian Inheritance in Man (MIM) cross-references in UniProtKB/Swiss-Prot
  3. Human chromosome 19
    Human chromosome 19: entries, gene names and cross-references to MIM
  4. Human entries with polymorphisms or disease mutations
    List of human entries with polymorphisms or disease mutations
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