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Protein

Solute carrier family 46 member 3

Gene

SLC46A3

Organism
Bos taurus (Bovine)
Status
Reviewed-Annotation score: -Experimental evidence at transcript leveli

Functioni

GO - Biological processi

Names & Taxonomyi

Protein namesi
Recommended name:
Solute carrier family 46 member 3
Gene namesi
Name:SLC46A3
OrganismiBos taurus (Bovine)
Taxonomic identifieri9913 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaLaurasiatheriaCetartiodactylaRuminantiaPecoraBovidaeBovinaeBos
Proteomesi
  • UP000009136 Componenti: Unplaced

Subcellular locationi

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Topological domaini26 – 70ExtracellularSequence analysisAdd BLAST45
Transmembranei71 – 91HelicalSequence analysisAdd BLAST21
Topological domaini92 – 101CytoplasmicSequence analysis10
Transmembranei102 – 124HelicalSequence analysisAdd BLAST23
Topological domaini125 – 133ExtracellularSequence analysis9
Transmembranei134 – 156HelicalSequence analysisAdd BLAST23
Topological domaini157 – 170CytoplasmicSequence analysisAdd BLAST14
Transmembranei171 – 191HelicalSequence analysisAdd BLAST21
Topological domaini192 – 195ExtracellularSequence analysis4
Transmembranei196 – 216HelicalSequence analysisAdd BLAST21
Topological domaini217 – 261CytoplasmicSequence analysisAdd BLAST45
Transmembranei262 – 282HelicalSequence analysisAdd BLAST21
Topological domaini283 – 294ExtracellularSequence analysisAdd BLAST12
Transmembranei295 – 315HelicalSequence analysisAdd BLAST21
Topological domaini316 – 324CytoplasmicSequence analysis9
Transmembranei325 – 345HelicalSequence analysisAdd BLAST21
Topological domaini346 – 347ExtracellularSequence analysis2
Transmembranei348 – 368HelicalSequence analysisAdd BLAST21
Topological domaini369 – 382CytoplasmicSequence analysisAdd BLAST14
Transmembranei383 – 403HelicalSequence analysisAdd BLAST21
Topological domaini404 – 415ExtracellularSequence analysisAdd BLAST12
Transmembranei416 – 436HelicalSequence analysisAdd BLAST21
Topological domaini437 – 461CytoplasmicSequence analysisAdd BLAST25

Keywords - Cellular componenti

Membrane

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Signal peptidei1 – 25Sequence analysisAdd BLAST25
ChainiPRO_000030725226 – 461Solute carrier family 46 member 3Add BLAST436

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Glycosylationi38N-linked (GlcNAc...) asparagineSequence analysis1
Glycosylationi46N-linked (GlcNAc...) asparagineSequence analysis1
Glycosylationi53N-linked (GlcNAc...) asparagineSequence analysis1

Keywords - PTMi

Glycoprotein

Proteomic databases

PaxDbiA5D7V7
PRIDEiA5D7V7

Interactioni

Protein-protein interaction databases

STRINGi9913.ENSBTAP00000011448

Family & Domainsi

Sequence similaritiesi

Keywords - Domaini

Signal, Transmembrane, Transmembrane helix

Phylogenomic databases

eggNOGiKOG2816 Eukaryota
ENOG410ZVCA LUCA
HOGENOMiHOG000074207
HOVERGENiHBG108453
InParanoidiA5D7V7
KOiK20840

Family and domain databases

CDDicd06174 MFS, 1 hit
InterProiView protein in InterPro
IPR011701 MFS
IPR020846 MFS_dom
IPR036259 MFS_trans_sf
PfamiView protein in Pfam
PF07690 MFS_1, 1 hit
SUPFAMiSSF103473 SSF103473, 1 hit

Sequencei

Sequence statusi: Complete.

Sequence processingi: The displayed sequence is further processed into a mature form.

A5D7V7-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MKIPFVEPVI CLSVFAVTLN SPLTTQYVYR RIWEETGNYS IALESNTSEC
60 70 80 90 100
AKNKSSPIFA FQEEVQKKVS LFNLEMDISG LIPGLVSTFV FLSHSDHGGR
110 120 130 140 150
KFPLILSSVG ALANSAWLCL LSYFALPIQL LIASTFIGAL FGNYTTFLGA
160 170 180 190 200
SFAYIVDQCK EKKQRTIRIA IIDFLFGVVS GLTGLSSGYF IRGLGFVWSF
210 220 230 240 250
LIVTVALFVN LIYILLFLED SMKESSSQNI SVSWTETFKN LFHRTYMLFK
260 270 280 290 300
NASGEQQSLC CLLLFTMITY FFVTIGVSPI FVLYELDSPL CWDEVLIGYG
310 320 330 340 350
SALGSVTFFS SFLGIWLFSY CMEDIHMAFI GTFTTMVGMA MTAFARTTLM
360 370 380 390 400
MFLVRLPFLF TVMPLSVLRS MISKVVHSTE QGTMFACLAF LETLGGITAV
410 420 430 440 450
STFNGIYSAT VAWCKGFVFL LSAVLLLIPA ISLCVIKYVS RNTGSYVLLI
460
QEESSEDTSD R
Length:461
Mass (Da):51,303
Last modified:June 12, 2007 - v1
Checksum:iB9500CB81C503A5F
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BC140697 mRNA Translation: AAI40698.1
RefSeqiNP_001096773.1, NM_001103303.2
UniGeneiBt.9454

Genome annotation databases

GeneIDi781117
KEGGibta:781117

Similar proteinsi

Entry informationi

Entry nameiS46A3_BOVIN
AccessioniPrimary (citable) accession number: A5D7V7
Entry historyiIntegrated into UniProtKB/Swiss-Prot: October 23, 2007
Last sequence update: June 12, 2007
Last modified: October 25, 2017
This is version 49 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families

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