UniProtKB - A5D7N2 (A5D7N2_BOVIN)
Protein
Histone H2B
Gene
HIST2H2BE
Organism
Bos taurus (Bovine)
Status
Functioni
GO - Molecular functioni
- DNA binding Source: UniProtKB-KW
- protein heterodimerization activity Source: InterPro
Keywordsi
Molecular function | DNA-binding |
Names & Taxonomyi
Protein namesi | Recommended name: Histone H2BUniRule annotation |
Gene namesi | Name:HIST2H2BEImported |
Organismi | Bos taurus (Bovine)Imported |
Taxonomic identifieri | 9913 [NCBI] |
Taxonomic lineagei | Eukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Mammalia › Eutheria › Laurasiatheria › Artiodactyla › Ruminantia › Pecora › Bovidae › Bovinae › Bos |
Subcellular locationi
Nucleus
- Nucleus UniRule annotation
Nucleus
- nucleus Source: UniProtKB-SubCell
Other locations
- nucleosome Source: UniProtKB-KW
Keywords - Cellular componenti
Chromosome, Nucleosome coreUniRule annotation, NucleusUniRule annotationInteractioni
Subunit structurei
The nucleosome is a histone octamer containing two molecules each of H2A, H2B, H3 and H4 assembled in one H3-H4 heterotetramer and two H2A-H2B heterodimers. The octamer wraps approximately 147 bp of DNA.
UniRule annotationGO - Molecular functioni
- protein heterodimerization activity Source: InterPro
Family & Domainsi
Domains and Repeats
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Domaini | 10 – 101 | HistoneInterPro annotationAdd BLAST | 92 |
Region
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Regioni | 1 – 35 | DisorderedSequence analysisAdd BLAST | 35 |
Compositional bias
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Compositional biasi | 17 – 35 | BasicSequence analysisAdd BLAST | 19 |
Sequence similaritiesi
Phylogenomic databases
OMAi | DIFDRMA |
OrthoDBi | 1536672at2759 |
Family and domain databases
Gene3Di | 1.10.20.10, 1 hit |
InterProi | View protein in InterPro IPR009072, Histone-fold IPR007125, Histone_H2A/H2B/H3 IPR000558, Histone_H2B |
PANTHERi | PTHR23428, PTHR23428, 1 hit |
Pfami | View protein in Pfam PF00125, Histone, 1 hit |
PRINTSi | PR00621, HISTONEH2B |
SMARTi | View protein in SMART SM00427, H2B, 1 hit |
SUPFAMi | SSF47113, SSF47113, 1 hit |
PROSITEi | View protein in PROSITE PS00357, HISTONE_H2B, 1 hit |
i Sequence
Sequence statusi: Complete.
A5D7N2-1 [UniParc]FASTAAdd to basket
10 20 30 40 50
MPEPAKSAPA PKKGSKKAVT KAQKKDGKKR KRSRKESYSI YVYKVLKQVH
60 70 80 90 100
PDTGISSKAM GIMNSFVNDI FERIAGEASR LAHYNKRSTI TSREIQTAVR
110 120
LLLPGELAKH AVSEGTKAVT KYTSSK
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | BC140622 mRNA Translation: AAI40623.1 |
RefSeqi | NP_001092854.1, NM_001099384.1 |
Genome annotation databases
GeneIDi | 537985 |
KEGGi | bta:537985 |
Similar proteinsi
Cross-referencesi
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | BC140622 mRNA Translation: AAI40623.1 |
RefSeqi | NP_001092854.1, NM_001099384.1 |
3D structure databases
SMRi | A5D7N2 |
ModBasei | Search... |
Genome annotation databases
GeneIDi | 537985 |
KEGGi | bta:537985 |
Organism-specific databases
CTDi | 8349 |
Phylogenomic databases
OMAi | DIFDRMA |
OrthoDBi | 1536672at2759 |
Family and domain databases
Gene3Di | 1.10.20.10, 1 hit |
InterProi | View protein in InterPro IPR009072, Histone-fold IPR007125, Histone_H2A/H2B/H3 IPR000558, Histone_H2B |
PANTHERi | PTHR23428, PTHR23428, 1 hit |
Pfami | View protein in Pfam PF00125, Histone, 1 hit |
PRINTSi | PR00621, HISTONEH2B |
SMARTi | View protein in SMART SM00427, H2B, 1 hit |
SUPFAMi | SSF47113, SSF47113, 1 hit |
PROSITEi | View protein in PROSITE PS00357, HISTONE_H2B, 1 hit |
ProtoNeti | Search... |
MobiDBi | Search... |
Entry informationi
Entry namei | A5D7N2_BOVIN | |
Accessioni | A5D7N2Primary (citable) accession number: A5D7N2 | |
Entry historyi | Integrated into UniProtKB/TrEMBL: | June 12, 2007 |
Last sequence update: | June 12, 2007 | |
Last modified: | April 7, 2021 | |
This is version 86 of the entry and version 1 of the sequence. See complete history. | ||
Entry statusi | Unreviewed (UniProtKB/TrEMBL) |