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Entry version 93 (10 Feb 2021)
Sequence version 1 (12 Jun 2007)
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Protein

Fat storage-inducing transmembrane protein 1

Gene

FITM1

Organism
Homo sapiens (Human)
Status
Reviewed-Annotation score:

Annotation score:4 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Experimental evidence at transcript leveli <p>This indicates the type of evidence that supports the existence of the protein. Note that the 'protein existence' evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

Plays an important role in the formation of lipid droplets (LDs) which are storage organelles at the center of lipid and energy homeostasis (PubMed:18160536) (By similarity). Directly binds to diacylglycerol (DAGs) and triacylglycerol (By similarity).UniRule annotation1 Publication

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/function%5Fsection">Function</a> section is used for enzymes and indicates the residues directly involved in catalysis.<p><a href='/help/act_site' target='_top'>More...</a></p>Active sitei186UniRule annotation1
Active sitei244UniRule annotation1
<p>This subsection describes interesting single amino acid sites on the sequence that are not defined in any other subsection. This subsection can be displayed in different sections ('Function', 'PTM / Processing', 'Pathology and Biotech') according to its content.<p><a href='/help/site' target='_top'>More...</a></p>Sitei248Important for catalytic activityUniRule annotation1

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

GO - Biological processi

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywordsi

Biological processLipid metabolism

Enzyme and pathway databases

Pathway Commons web resource for biological pathway data

More...
PathwayCommonsi
A5D6W6

Reactome - a knowledgebase of biological pathways and processes

More...
Reactomei
R-HSA-8964572, Lipid particle organization

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Recommended name:
Fat storage-inducing transmembrane protein 11 PublicationUniRule annotation
Alternative name(s):
Fat-inducing protein 1UniRule annotation
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: 'Name', 'Synonyms', 'Ordered locus names' and 'ORF names'.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:FITM1UniRule annotationImported
Synonyms:FIT1UniRule annotation
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiHomo sapiens (Human)
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the 'taxonomic identifier' or 'taxid'.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri9606 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000005640 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes%5Fmanual">proteome</a> can consist of several components.<br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome 14

Organism-specific databases

Human Gene Nomenclature Database

More...
HGNCi
HGNC:33714, FITM1

Online Mendelian Inheritance in Man (OMIM)

More...
MIMi
612028, gene

neXtProt; the human protein knowledge platform

More...
neXtProti
NX_A5D6W6

Eukaryotic Pathogen, Vector and Host Database Resources

More...
VEuPathDBi
HostDB:ENSG00000139914.6

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte & Seán O’Donoghue; Source: COMPARTMENTS

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/subcellular%5Flocation%5Fsection">'Subcellular location'</a> section describes the subcellular compartment where each non-membrane region of a membrane-spanning protein is found.<p><a href='/help/topo_dom' target='_top'>More...</a></p>Topological domaini1 – 18LumenalCuratedAdd BLAST18
<p>This subsection of the <a href="http://www.uniprot.org/help/subcellular%5Flocation%5Fsection">'Subcellular location'</a> section describes the extent of a membrane-spanning region of the protein. It denotes the presence of both alpha-helical transmembrane regions and the membrane spanning regions of beta-barrel transmembrane proteins.<p><a href='/help/transmem' target='_top'>More...</a></p>Transmembranei19 – 39HelicalSequence analysisAdd BLAST21
Topological domaini40 – 54CytoplasmicCuratedAdd BLAST15
Transmembranei55 – 75HelicalSequence analysisAdd BLAST21
Topological domaini76 – 94LumenalCuratedAdd BLAST19
Transmembranei95 – 115HelicalSequence analysisAdd BLAST21
Topological domaini116 – 141CytoplasmicCuratedAdd BLAST26
Transmembranei142 – 162HelicalSequence analysisAdd BLAST21
Topological domaini163 – 187LumenalCuratedAdd BLAST25
Transmembranei188 – 208HelicalSequence analysisAdd BLAST21
Topological domaini209 – 220CytoplasmicCuratedAdd BLAST12
Transmembranei221 – 241HelicalSequence analysisAdd BLAST21
Topological domaini242 – 249LumenalCurated8
Transmembranei250 – 270HelicalSequence analysisAdd BLAST21
Topological domaini271 – 292CytoplasmicCuratedAdd BLAST22

Keywords - Cellular componenti

Endoplasmic reticulum, Membrane

<p>This section provides information on the disease(s) and phenotype(s) associated with a protein.<p><a href='/help/pathology_and_biotech_section' target='_top'>More...</a></p>Pathology & Biotechi

Organism-specific databases

DisGeNET

More...
DisGeNETi
161247

Open Targets

More...
OpenTargetsi
ENSG00000139914

The Pharmacogenetics and Pharmacogenomics Knowledge Base

More...
PharmGKBi
PA165478932

Miscellaneous databases

Pharos NIH Druggable Genome Knowledgebase

More...
Pharosi
A5D6W6, Tdark

Genetic variation databases

BioMuta curated single-nucleotide variation and disease association database

More...
BioMutai
FITM1

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'PTM / Processing' section describes the extent of a polypeptide chain in the mature protein following processing or proteolytic cleavage.<p><a href='/help/chain' target='_top'>More...</a></p>ChainiPRO_00003195751 – 292Fat storage-inducing transmembrane protein 1Add BLAST292

Proteomic databases

jPOST - Japan Proteome Standard Repository/Database

More...
jPOSTi
A5D6W6

MassIVE - Mass Spectrometry Interactive Virtual Environment

More...
MassIVEi
A5D6W6

PaxDb, a database of protein abundance averages across all three domains of life

More...
PaxDbi
A5D6W6

PeptideAtlas

More...
PeptideAtlasi
A5D6W6

PRoteomics IDEntifications database

More...
PRIDEi
A5D6W6

ProteomicsDB: a multi-organism proteome resource

More...
ProteomicsDBi
707 [A5D6W6-1]
708 [A5D6W6-2]

PTM databases

iPTMnet integrated resource for PTMs in systems biology context

More...
iPTMneti
A5D6W6

Comprehensive resource for the study of protein post-translational modifications (PTMs) in human, mouse and rat.

More...
PhosphoSitePlusi
A5D6W6

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

<p>This subsection of the 'Expression' section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms. By default, the information is derived from experiments at the mRNA level, unless specified 'at protein level'.<br></br>Examples: <a href="http://www.uniprot.org/uniprot/P92958#expression">P92958</a>, <a href="http://www.uniprot.org/uniprot/Q8TDN4#expression">Q8TDN4</a>, <a href="http://www.uniprot.org/uniprot/O14734#expression">O14734</a><p><a href='/help/tissue_specificity' target='_top'>More...</a></p>Tissue specificityi

Primarily expressed in heart and skeletal muscle.1 Publication

Gene expression databases

Bgee dataBase for Gene Expression Evolution

More...
Bgeei
ENSG00000139914, Expressed in muscle of leg and 107 other tissues

Genevisible search portal to normalized and curated expression data from Genevestigator

More...
Genevisiblei
A5D6W6, HS

Organism-specific databases

Human Protein Atlas

More...
HPAi
ENSG00000139914, Group enriched (heart muscle, skeletal muscle, tongue)

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

Protein-protein interaction databases

The Biological General Repository for Interaction Datasets (BioGRID)

More...
BioGRIDi
127777, 1 interactor

STRING: functional protein association networks

More...
STRINGi
9606.ENSP00000267426

Miscellaneous databases

RNAct, Protein-RNA interaction predictions for model organisms.

More...
RNActi
A5D6W6, protein

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

<p>This subsection of the 'Family and domains' section provides information about the sequence similarity with other proteins.<p><a href='/help/sequence_similarities' target='_top'>More...</a></p>Sequence similaritiesi

Belongs to the FIT family. FIT1 subfamily.UniRule annotation

Keywords - Domaini

Transmembrane, Transmembrane helix

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

More...
eggNOGi
KOG3750, Eukaryota

Ensembl GeneTree

More...
GeneTreei
ENSGT00530000063693

The HOGENOM Database of Homologous Genes from Fully Sequenced Organisms

More...
HOGENOMi
CLU_049499_2_0_1

InParanoid: Eukaryotic Ortholog Groups

More...
InParanoidi
A5D6W6

Identification of Orthologs from Complete Genome Data

More...
OMAi
FPQFPTQ

Database of Orthologous Groups

More...
OrthoDBi
1621925at2759

Database for complete collections of gene phylogenies

More...
PhylomeDBi
A5D6W6

Family and domain databases

Integrated resource of protein families, domains and functional sites

More...
InterProi
View protein in InterPro
IPR019388, FIT

The PANTHER Classification System

More...
PANTHERi
PTHR23129, PTHR23129, 1 hit

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence%5Flength">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequences (2)i

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences%5Fsection">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

This entry describes 2 <p>This subsection of the 'Sequence' section lists the alternative protein sequences (isoforms) that can be generated from the same gene by a single or by the combination of up to four biological events (alternative promoter usage, alternative splicing, alternative initiation and ribosomal frameshifting). Additionally, this section gives relevant information on each alternative protein isoform. This section is only present in reviewed entries, i.e. in UniProtKB/Swiss-Prot.<p><a href='/help/alternative_products' target='_top'>More...</a></p> isoformsi produced by alternative splicing. AlignAdd to basket
Isoform 1 (identifier: A5D6W6-1) [UniParc]FASTAAdd to basket

This isoform has been chosen as the <div> <p><b>What is the canonical sequence?</b><p><a href='/help/canonical_and_isoforms' target='_top'>More...</a></p>canonicali sequence. All positional information in this entry refers to it. This is also the sequence that appears in the downloadable versions of the entry.

« Hide
        10         20         30         40         50
MERGPVVGAG LGAGARIQAL LGCLLKVLLW VASALLYFGS EQAARLLGSP
60 70 80 90 100
CLRRLYHAWL AAVVIFGPLL QFHVNPRTIF ASHGNFFNIK FVNSAWGWTC
110 120 130 140 150
TFLGGFVLLV VFLATRRVAV TARHLSRLVV GAAVWRGAGR AFLLIEDLTG
160 170 180 190 200
SCFEPLPQGL LLHELPDRRS CLAAGHQWRG YTVSSHTFLL TFCCLLMAEE
210 220 230 240 250
AAVFAKYLAH GLPAGAPLRL VFLLNVLLLG LWNFLLLCTV IYFHQYTHKV
260 270 280 290
VGAAVGTFAW YLTYGSWYHQ PWSPGSPGHG LFPRPHSSRK HN
Length:292
Mass (Da):32,207
Last modified:June 12, 2007 - v1
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:i5722083EB85EEDC8
GO
Isoform 2 (identifier: A5D6W6-2) [UniParc]FASTAAdd to basket

The sequence of this isoform differs from the canonical sequence as follows:
     1-196: Missing.

Show »
Length:96
Mass (Da):10,778
Checksum:iF8250E362DE96701
GO

Alternative sequence

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Sequence' section describes the sequence of naturally occurring alternative protein isoform(s). The changes in the amino acid sequence may be due to alternative splicing, alternative promoter usage, alternative initiation, or ribosomal frameshifting.<p><a href='/help/var_seq' target='_top'>More...</a></p>Alternative sequenceiVSP_0314931 – 196Missing in isoform 2. 1 PublicationAdd BLAST196

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...
EMBLi

GenBank nucleotide sequence database

More...
GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...
DDBJi
Links Updated
CH471078 Genomic DNA Translation: EAW66107.1
BC042179 mRNA No translation available.
BC139911 mRNA Translation: AAI39912.1

The Consensus CDS (CCDS) project

More...
CCDSi
CCDS9611.1 [A5D6W6-1]

NCBI Reference Sequences

More...
RefSeqi
NP_981947.1, NM_203402.2 [A5D6W6-1]

Genome annotation databases

Ensembl eukaryotic genome annotation project

More...
Ensembli
ENST00000267426; ENSP00000267426; ENSG00000139914 [A5D6W6-1]
ENST00000559294; ENSP00000453741; ENSG00000139914 [A5D6W6-2]
ENST00000642380; ENSP00000493481; ENSG00000285321 [A5D6W6-2]
ENST00000644407; ENSP00000493961; ENSG00000285321 [A5D6W6-1]

Database of genes from NCBI RefSeq genomes

More...
GeneIDi
161247

KEGG: Kyoto Encyclopedia of Genes and Genomes

More...
KEGGi
hsa:161247

UCSC genome browser

More...
UCSCi
uc001wmf.3, human [A5D6W6-1]

Keywords - Coding sequence diversityi

Alternative splicing

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CH471078 Genomic DNA Translation: EAW66107.1
BC042179 mRNA No translation available.
BC139911 mRNA Translation: AAI39912.1
CCDSiCCDS9611.1 [A5D6W6-1]
RefSeqiNP_981947.1, NM_203402.2 [A5D6W6-1]

3D structure databases

Database of comparative protein structure models

More...
ModBasei
Search...

SWISS-MODEL Interactive Workspace

More...
SWISS-MODEL-Workspacei
Submit a new modelling project...

Protein-protein interaction databases

BioGRIDi127777, 1 interactor
STRINGi9606.ENSP00000267426

PTM databases

iPTMnetiA5D6W6
PhosphoSitePlusiA5D6W6

Genetic variation databases

BioMutaiFITM1

Proteomic databases

jPOSTiA5D6W6
MassIVEiA5D6W6
PaxDbiA5D6W6
PeptideAtlasiA5D6W6
PRIDEiA5D6W6
ProteomicsDBi707 [A5D6W6-1]
708 [A5D6W6-2]

Protocols and materials databases

Antibodypedia a portal for validated antibodies

More...
Antibodypediai
8923, 41 antibodies

Genome annotation databases

EnsembliENST00000267426; ENSP00000267426; ENSG00000139914 [A5D6W6-1]
ENST00000559294; ENSP00000453741; ENSG00000139914 [A5D6W6-2]
ENST00000642380; ENSP00000493481; ENSG00000285321 [A5D6W6-2]
ENST00000644407; ENSP00000493961; ENSG00000285321 [A5D6W6-1]
GeneIDi161247
KEGGihsa:161247
UCSCiuc001wmf.3, human [A5D6W6-1]

Organism-specific databases

Comparative Toxicogenomics Database

More...
CTDi
161247
DisGeNETi161247

GeneCards: human genes, protein and diseases

More...
GeneCardsi
FITM1
HGNCiHGNC:33714, FITM1
HPAiENSG00000139914, Group enriched (heart muscle, skeletal muscle, tongue)
MIMi612028, gene
neXtProtiNX_A5D6W6
OpenTargetsiENSG00000139914
PharmGKBiPA165478932
VEuPathDBiHostDB:ENSG00000139914.6

GenAtlas: human gene database

More...
GenAtlasi
Search...

Phylogenomic databases

eggNOGiKOG3750, Eukaryota
GeneTreeiENSGT00530000063693
HOGENOMiCLU_049499_2_0_1
InParanoidiA5D6W6
OMAiFPQFPTQ
OrthoDBi1621925at2759
PhylomeDBiA5D6W6

Enzyme and pathway databases

PathwayCommonsiA5D6W6
ReactomeiR-HSA-8964572, Lipid particle organization

Miscellaneous databases

BioGRID ORCS database of CRISPR phenotype screens

More...
BioGRID-ORCSi
161247, 9 hits in 873 CRISPR screens

ChiTaRS: a database of human, mouse and fruit fly chimeric transcripts and RNA-sequencing data

More...
ChiTaRSi
FITM1, human

Database of phenotypes from RNA interference screens in Drosophila and Homo sapiens

More...
GenomeRNAii
161247
PharosiA5D6W6, Tdark

Protein Ontology

More...
PROi
PR:A5D6W6
RNActiA5D6W6, protein

The Stanford Online Universal Resource for Clones and ESTs

More...
SOURCEi
Search...

Gene expression databases

BgeeiENSG00000139914, Expressed in muscle of leg and 107 other tissues
GenevisibleiA5D6W6, HS

Family and domain databases

InterProiView protein in InterPro
IPR019388, FIT
PANTHERiPTHR23129, PTHR23129, 1 hit

ProtoNet; Automatic hierarchical classification of proteins

More...
ProtoNeti
Search...

MobiDB: a database of protein disorder and mobility annotations

More...
MobiDBi
Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the 'Entry information' section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiFITM1_HUMAN
<p>This subsection of the 'Entry information' section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called 'Primary (citable) accession number'.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: A5D6W6
Secondary accession number(s): Q8IUQ7
<p>This subsection of the 'Entry information' section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification ('Last modified'). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/Swiss-Prot: February 26, 2008
Last sequence update: June 12, 2007
Last modified: February 10, 2021
This is version 93 of the entry and version 1 of the sequence. See complete history.
<p>This subsection of the 'Entry information' section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

<p>This section contains any relevant information that doesn't fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Reference proteome

Documents

  1. Human chromosome 14
    Human chromosome 14: entries, gene names and cross-references to MIM
  2. MIM cross-references
    Online Mendelian Inheritance in Man (MIM) cross-references in UniProtKB/Swiss-Prot
  3. SIMILARITY comments
    Index of protein domains and families
  4. Uncharacterized protein families (UPF)
    List of uncharacterized protein family (UPF) entries
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