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UniProtKB - A5CVE4 (A5CVE4_MOUSE)
Protein
Submitted name:
Stromal interaction molecule 2
Gene
Stim2
Organism
Mus musculus (Mouse)
Status
Functioni
GO - Molecular functioni
- calcium channel regulator activity Source: InterPro
- metal ion binding Source: UniProtKB-KW
GO - Biological processi
- calcium ion transport Source: UniProtKB-KW
- cellular calcium ion homeostasis Source: InterPro
Keywordsi
Biological process | Calcium transportARBA annotation, Ion transport, Transport |
Ligand | Calcium, Metal-bindingARBA annotation |
Names & Taxonomyi
Protein namesi | Submitted name: Stromal interaction molecule 2Imported |
Gene namesi | Name:Stim2Imported |
Organismi | Mus musculus (Mouse)Imported |
Taxonomic identifieri | 10090 [NCBI] |
Taxonomic lineagei | Eukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Mammalia › Eutheria › Euarchontoglires › Glires › Rodentia › Myomorpha › Muroidea › Muridae › Murinae › Mus › Mus |
Organism-specific databases
MGIi | MGI:2151156, Stim2 |
VEuPathDBi | HostDB:ENSMUSG00000039156 |
Subcellular locationi
Endoplasmic reticulum
- Endoplasmic reticulum membrane ARBA annotation; Single-pass type I membrane protein ARBA annotation
Other locations
- Membrane ARBA annotation; Single-pass type I membrane protein ARBA annotation
Endoplasmic reticulum
- endoplasmic reticulum membrane Source: UniProtKB-SubCell
Other locations
- integral component of membrane Source: UniProtKB-KW
Keywords - Cellular componenti
MembraneExpressioni
Gene expression databases
Bgeei | ENSMUSG00000039156, Expressed in vestibular membrane of cochlear duct and 263 other tissues |
Family & Domainsi
Domains and Repeats
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Domaini | 136 – 194 | SAMInterPro annotationAdd BLAST | 59 |
Region
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Regioni | 490 – 562 | DisorderedSequence analysisAdd BLAST | 73 | |
Regioni | 592 – 651 | DisorderedSequence analysisAdd BLAST | 60 | |
Regioni | 684 – 746 | DisorderedSequence analysisAdd BLAST | 63 |
Coiled coil
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Coiled coili | 252 – 289 | Sequence analysisAdd BLAST | 38 | |
Coiled coili | 318 – 338 | Sequence analysisAdd BLAST | 21 | |
Coiled coili | 370 – 390 | Sequence analysisAdd BLAST | 21 |
Compositional bias
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Compositional biasi | 504 – 530 | Polar residuesSequence analysisAdd BLAST | 27 | |
Compositional biasi | 594 – 625 | Polar residuesSequence analysisAdd BLAST | 32 | |
Compositional biasi | 684 – 720 | Polar residuesSequence analysisAdd BLAST | 37 |
Keywords - Domaini
Coiled coilSequence analysisARBA annotation, SignalARBA annotation, Transmembrane, Transmembrane helixARBA annotationPhylogenomic databases
HOGENOMi | CLU_010588_2_0_1 |
OMAi | ISDPCMS |
OrthoDBi | 373308at2759 |
PhylomeDBi | A5CVE4 |
Family and domain databases
CDDi | cd09574, SAM_STIM2, 1 hit cd11722, SOAR, 1 hit |
Gene3Di | 1.10.150.50, 1 hit |
InterProi | View protein in InterPro IPR001660, SAM IPR013761, SAM/pointed_sf IPR032393, SOAR IPR037608, STIM IPR037610, STIM2_SAM |
PANTHERi | PTHR15136, PTHR15136, 1 hit |
Pfami | View protein in Pfam PF07647, SAM_2, 1 hit PF16533, SOAR, 1 hit |
SMARTi | View protein in SMART SM00454, SAM, 1 hit |
SUPFAMi | SSF47769, SSF47769, 1 hit |
PROSITEi | View protein in PROSITE PS50105, SAM_DOMAIN, 1 hit |
i Sequence
Sequence statusi: Complete.
A5CVE4-1 [UniParc]FASTAAdd to basket
10 20 30 40 50
MLLFGLLVAG VADGCDLVPR HLRGRRASGS AGAAASPSAA AAGERQALLT
60 70 80 90 100
DPCMSLSPPC FTEEDRFSLE ALQTIHKQMD DDKDGGIEVD ESDEFIREDM
110 120 130 140 150
KYKDATNKHS HLHREDKHIT VEDLWKQWKT SEVHNWTLED TLQWLIEFVE
160 170 180 190 200
LPQYEKNFRD NNVKGTTLPR IAVHETSFMI SQLKISDRSH RQKLQLKALD
210 220 230 240 250
VVLFGPLTRP PHNWMKDFIL TISIVIGVGG CWFAYTQNKT SKEHVAKMMK
260 270 280 290 300
DLESLQTAEQ SLMDLQERLE KAQEENRTVA VEKQNLERKM MDEINYAKEE
310 320 330 340 350
ACRLRELREG AECELSRRQY AEQELEQVRM ALKKAEKEFE LRSSWSVPDA
360 370 380 390 400
LQKWLQLTHE VEVQYYNIKR QNAEMQLAIA KDEAEKIKKK RSTVFGTLHV
410 420 430 440 450
AHSSSLDEVD HKILEAKKAL SELTTCLRER LFRWQQIEKI CGFQIAHNSG
460 470 480 490 500
LPSLTSSLYS DHSWVVMPRV SIPPYPIAGG VDDLDEDTPP IVPQFPGTVA
510 520 530 540 550
KPAGSLARSS SLCRSRRSIV PSSPQSQRAQ LPAHAPLAAH PRHPHHPQHP
560 570 580 590 600
QHSLPSPDPD ILSVSSCPAL YRNEEEEEAI YFTAEKQWEV PDTASECDSL
610 620 630 640 650
NSSSGRKPSP PSSLEMYQTL SSRKISRDEL SLEDSSRGES PVTADVSRGS
660 670 680 690 700
PECVGLTETK SMIFSPASRV YNGILEKSCS MHQLSSGIPV PHPRHTSCSS
710 720 730 740
AGNDSKPVQE ASNVSRVSSI PHDLCHNGEK SKKPSKIKSL FKKKSK
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | AM712359 mRNA Translation: CAN36430.1 |
RefSeqi | NP_001074572.2, NM_001081103.2 |
Genome annotation databases
GeneIDi | 116873 |
KEGGi | mmu:116873 |
Similar proteinsi
Cross-referencesi
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | AM712359 mRNA Translation: CAN36430.1 |
RefSeqi | NP_001074572.2, NM_001081103.2 |
3D structure databases
SMRi | A5CVE4 |
ModBasei | Search... |
PTM databases
SwissPalmi | A5CVE4 |
Proteomic databases
EPDi | A5CVE4 |
PeptideAtlasi | A5CVE4 |
Protocols and materials databases
Antibodypediai | 10303, 273 antibodies from 36 providers |
DNASUi | 116873 |
Genome annotation databases
GeneIDi | 116873 |
KEGGi | mmu:116873 |
Organism-specific databases
CTDi | 57620 |
MGIi | MGI:2151156, Stim2 |
VEuPathDBi | HostDB:ENSMUSG00000039156 |
Phylogenomic databases
HOGENOMi | CLU_010588_2_0_1 |
OMAi | ISDPCMS |
OrthoDBi | 373308at2759 |
PhylomeDBi | A5CVE4 |
Miscellaneous databases
BioGRID-ORCSi | 116873, 3 hits in 71 CRISPR screens |
ChiTaRSi | Stim2, mouse |
SOURCEi | Search... |
Gene expression databases
Bgeei | ENSMUSG00000039156, Expressed in vestibular membrane of cochlear duct and 263 other tissues |
Family and domain databases
CDDi | cd09574, SAM_STIM2, 1 hit cd11722, SOAR, 1 hit |
Gene3Di | 1.10.150.50, 1 hit |
InterProi | View protein in InterPro IPR001660, SAM IPR013761, SAM/pointed_sf IPR032393, SOAR IPR037608, STIM IPR037610, STIM2_SAM |
PANTHERi | PTHR15136, PTHR15136, 1 hit |
Pfami | View protein in Pfam PF07647, SAM_2, 1 hit PF16533, SOAR, 1 hit |
SMARTi | View protein in SMART SM00454, SAM, 1 hit |
SUPFAMi | SSF47769, SSF47769, 1 hit |
PROSITEi | View protein in PROSITE PS50105, SAM_DOMAIN, 1 hit |
MobiDBi | Search... |
Entry informationi
Entry namei | A5CVE4_MOUSE | |
Accessioni | A5CVE4Primary (citable) accession number: A5CVE4 | |
Entry historyi | Integrated into UniProtKB/TrEMBL: | June 12, 2007 |
Last sequence update: | June 12, 2007 | |
Last modified: | May 25, 2022 | |
This is version 109 of the entry and version 1 of the sequence. See complete history. | ||
Entry statusi | Unreviewed (UniProtKB/TrEMBL) |