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Entry version 73 (26 Feb 2020)
Sequence version 1 (12 Jun 2007)
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Protein

BHLH domain-containing protein

Gene

VIT_02s0025g02310

Organism
Vitis vinifera (Grape)
Status
Unreviewed-Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Protein predictedi <p>This indicates the type of evidence that supports the existence of the protein. Note that the 'protein existence' evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Recommended name:
BHLH domain-containing proteinInterPro annotation
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: 'Name', 'Synonyms', 'Ordered locus names' and 'ORF names'.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Ordered Locus Names:VIT_02s0025g02310Imported
ORF Names:VITISV_028112Imported
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiVitis vinifera (Grape)Imported
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the 'taxonomic identifier' or 'taxid'.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri29760 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryotaViridiplantaeStreptophytaEmbryophytaTracheophytaSpermatophytaMagnoliopsidaeudicotyledonsGunneridaePentapetalaerosidsVitalesVitaceaeViteaeVitis
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000009183 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes%5Fmanual">proteome</a> can consist of several components.<br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome 2

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

GO - Molecular functioni

Protein-protein interaction databases

STRING: functional protein association networks

More...
STRINGi
29760.VIT_02s0025g02310.t01

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/family%5Fand%5Fdomains%5Fsection">Family and Domains</a> section describes the position and type of a domain, which is defined as a specific combination of secondary structures organized into a characteristic three-dimensional structure or fold.<p><a href='/help/domain' target='_top'>More...</a></p>Domaini669 – 718BHLHInterPro annotationAdd BLAST50

Region

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Family and Domains' section describes a region of interest that cannot be described in other subsections.<p><a href='/help/region' target='_top'>More...</a></p>Regioni565 – 593DisorderedSequence analysisAdd BLAST29
Regioni649 – 684DisorderedSequence analysisAdd BLAST36
Regioni856 – 893DisorderedSequence analysisAdd BLAST38

Compositional bias

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Family and Domains' section describes the position of regions of compositional bias within the protein and the particular amino acids that are over-represented within those regions.<p><a href='/help/compbias' target='_top'>More...</a></p>Compositional biasi660 – 684PolyampholyteSequence analysisAdd BLAST25
Compositional biasi856 – 885PolarSequence analysisAdd BLAST30

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

More...
eggNOGi
ENOG410IHKX Eukaryota
ENOG410YD0M LUCA

The HOGENOM Database of Homologous Genes from Fully Sequenced Organisms

More...
HOGENOMi
CLU_013463_1_0_1

Database of Orthologous Groups

More...
OrthoDBi
673999at2759

Family and domain databases

Conserved Domains Database

More...
CDDi
cd00083 HLH, 1 hit

Integrated resource of protein families, domains and functional sites

More...
InterProi
View protein in InterPro
IPR011598 bHLH_dom
IPR036638 HLH_DNA-bd_sf
IPR025610 MYC/MYB_N

Pfam protein domain database

More...
Pfami
View protein in Pfam
PF14215 bHLH-MYC_N, 2 hits

Superfamily database of structural and functional annotation

More...
SUPFAMi
SSF47459 SSF47459, 1 hit

PROSITE; a protein domain and family database

More...
PROSITEi
View protein in PROSITE
PS50888 BHLH, 1 hit

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence%5Flength">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequencei

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences%5Fsection">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

A5BHT6-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MGGAVKMESV LKKTLKSLCC SNGWTYGVFW RFDERNSMLL TSEDAYYDEQ
60 70 80 90 100
MGVVIDSMLS KVHTLREGII GQVAFTGKHC WVFSDAQSGE WNSLCSIDGE
110 120 130 140 150
DISQDDSEIH RQFSSGIIKT IAVIPVEPRG VVQFGSNQKI VERLEFLDLT
160 170 180 190 200
KRLFREMENI DGLMVLSNAP SALNSEIYDP SGFFSSLISS GSSNLGNIKS
210 220 230 240 250
EHGNGHKELI EKASASTNLT QSSSFTPEMQ HERITSMISS TSHLRNQLQT
260 270 280 290 300
AGLEAQFMLS DQPNSQIQQM FLQSASSVNN PAARTPCIST WSSEGSTLTS
310 320 330 340 350
LERQLSSEMR AQVSQNAVPG KPNTVALWGN LVQDSQVDSM FTSLESTERL
360 370 380 390 400
IDEEKDFQCR LGKSVNNQYA APFIHATEGE LLEQSTSILT LPEECKPVDF
410 420 430 440 450
KTDPSKSYSV DNLSQWFGPP REQSIKGMAS MLTNDQSQSV GITSLSSGLD
460 470 480 490 500
RSDFLVDFPV KHPASSMQSS VINMFSSDGK ERSLNVPSTE NDLFDGLGLD
510 520 530 540 550
FGFELAGESW EDFIMPLFND GQSTLSTGVS ECISELDVGS MAVPRKGLFS
560 570 580 590 600
ELGLDQLLDD IVGNSSSVTK SNSEDQFSST KRRRLGSSSV NSNQVQSAGL
610 620 630 640 650
SSCFSGSMNV MQPVYNLDKT NSLVPKKEVI PKSQVGLWID DSYSINAGGS
660 670 680 690 700
VAAQPKRPVE PAKATKKRAK PGESTRPRPK DRQQIKDRLE ELRGIIPNGS
710 720 730 740 750
KCSIDVLLDR SIKHMLFLQS VTKYADKLKQ VDEPKLIGHE NGVVLKDNSS
760 770 780 790 800
GGSGNSGGGA TWAFEVSGQT MVCPIRVEDL NPPGQMLIEM LCEEQGFFLE
810 820 830 840 850
IADIIRSFGL NILKGVMEVR ENKIWARFIV EANRHVTRMD IFLSLVQLLQ
860 870 880 890
ETATTGVSPT NQPSNVIDSG VPPFNNYQQP SGPLPISLAE TLR
Length:893
Mass (Da):97,933
Last modified:June 12, 2007 - v1
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:i30DBB8CA864D271A
GO

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...
EMBLi

GenBank nucleotide sequence database

More...
GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...
DDBJi
Links Updated
AM459932 Genomic DNA Translation: CAN74602.1
FN596251 Genomic DNA Translation: CCB58283.1

NCBI Reference Sequences

More...
RefSeqi
XP_010659858.1, XM_010661556.2

Genome annotation databases

Ensembl plant genome annotation project

More...
EnsemblPlantsi
VIT_02s0025g02310.t01; VIT_02s0025g02310.t01; VIT_02s0025g02310

Database of genes from NCBI RefSeq genomes

More...
GeneIDi
100247886

Gramene; a comparative resource for plants

More...
Gramenei
VIT_02s0025g02310.t01; VIT_02s0025g02310.t01; VIT_02s0025g02310

KEGG: Kyoto Encyclopedia of Genes and Genomes

More...
KEGGi
vvi:100247886

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AM459932 Genomic DNA Translation: CAN74602.1
FN596251 Genomic DNA Translation: CCB58283.1
RefSeqiXP_010659858.1, XM_010661556.2

3D structure databases

Database of comparative protein structure models

More...
ModBasei
Search...

SWISS-MODEL Interactive Workspace

More...
SWISS-MODEL-Workspacei
Submit a new modelling project...

Protein-protein interaction databases

STRINGi29760.VIT_02s0025g02310.t01

Genome annotation databases

EnsemblPlantsiVIT_02s0025g02310.t01; VIT_02s0025g02310.t01; VIT_02s0025g02310
GeneIDi100247886
GrameneiVIT_02s0025g02310.t01; VIT_02s0025g02310.t01; VIT_02s0025g02310
KEGGivvi:100247886

Phylogenomic databases

eggNOGiENOG410IHKX Eukaryota
ENOG410YD0M LUCA
HOGENOMiCLU_013463_1_0_1
OrthoDBi673999at2759

Family and domain databases

CDDicd00083 HLH, 1 hit
InterProiView protein in InterPro
IPR011598 bHLH_dom
IPR036638 HLH_DNA-bd_sf
IPR025610 MYC/MYB_N
PfamiView protein in Pfam
PF14215 bHLH-MYC_N, 2 hits
SUPFAMiSSF47459 SSF47459, 1 hit
PROSITEiView protein in PROSITE
PS50888 BHLH, 1 hit

ProtoNet; Automatic hierarchical classification of proteins

More...
ProtoNeti
Search...

MobiDB: a database of protein disorder and mobility annotations

More...
MobiDBi
Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the 'Entry information' section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiA5BHT6_VITVI
<p>This subsection of the 'Entry information' section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called 'Primary (citable) accession number'.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: A5BHT6
<p>This subsection of the 'Entry information' section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification ('Last modified'). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/TrEMBL: June 12, 2007
Last sequence update: June 12, 2007
Last modified: February 26, 2020
This is version 73 of the entry and version 1 of the sequence. See complete history.
<p>This subsection of the 'Entry information' section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiUnreviewed (UniProtKB/TrEMBL)

<p>This section contains any relevant information that doesn't fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywords - Technical termi

Reference proteomeImported
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health

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