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Protein

Arginine--tRNA ligase

Gene

argS

Organism
Pseudomonas mendocina (strain ymp)
Status
Reviewed-Annotation score: -Protein inferred from homologyi

Functioni

Catalytic activityi

ATP + L-arginine + tRNA(Arg) = AMP + diphosphate + L-arginyl-tRNA(Arg).UniRule annotation

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionAminoacyl-tRNA synthetase, Ligase
Biological processProtein biosynthesis
LigandATP-binding, Nucleotide-binding

Enzyme and pathway databases

BioCyciPMEN399739:PMEN_RS02650-MONOMER

Names & Taxonomyi

Protein namesi
Recommended name:
Arginine--tRNA ligaseUniRule annotation (EC:6.1.1.19UniRule annotation)
Alternative name(s):
Arginyl-tRNA synthetaseUniRule annotation
Short name:
ArgRSUniRule annotation
Gene namesi
Name:argSUniRule annotation
Ordered Locus Names:Pmen_0535
OrganismiPseudomonas mendocina (strain ymp)
Taxonomic identifieri399739 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaPseudomonadalesPseudomonadaceaePseudomonas
Proteomesi
  • UP000000229 Componenti: Chromosome

Subcellular locationi

GO - Cellular componenti

Keywords - Cellular componenti

Cytoplasm

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_10000180931 – 579Arginine--tRNA ligaseAdd BLAST579

Interactioni

Subunit structurei

Monomer.UniRule annotation

Protein-protein interaction databases

STRINGi399739.Pmen_0535

Structurei

3D structure databases

ProteinModelPortaliA4XPN9
SMRiA4XPN9
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Motif

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Motifi127 – 137"HIGH" regionAdd BLAST11

Sequence similaritiesi

Belongs to the class-I aminoacyl-tRNA synthetase family.UniRule annotation

Phylogenomic databases

eggNOGiENOG4105C75 Bacteria
COG0018 LUCA
HOGENOMiHOG000247212
KOiK01887
OMAiNKPLHLG
OrthoDBiPOG091H01RF

Family and domain databases

CDDicd00671 ArgRS_core, 1 hit
Gene3Di3.30.1360.70, 1 hit
3.40.50.620, 1 hit
HAMAPiMF_00123 Arg_tRNA_synth, 1 hit
InterProiView protein in InterPro
IPR001412 aa-tRNA-synth_I_CS
IPR001278 Arg-tRNA-ligase
IPR005148 Arg-tRNA-synth_N
IPR036695 Arg-tRNA-synth_N_sf
IPR035684 ArgRS_core
IPR008909 DALR_anticod-bd
IPR014729 Rossmann-like_a/b/a_fold
IPR009080 tRNAsynth_Ia_anticodon-bd
PANTHERiPTHR11956 PTHR11956, 1 hit
PfamiView protein in Pfam
PF03485 Arg_tRNA_synt_N, 1 hit
PF05746 DALR_1, 1 hit
PF00750 tRNA-synt_1d, 1 hit
PRINTSiPR01038 TRNASYNTHARG
SMARTiView protein in SMART
SM01016 Arg_tRNA_synt_N, 1 hit
SM00836 DALR_1, 1 hit
SUPFAMiSSF47323 SSF47323, 1 hit
SSF55190 SSF55190, 1 hit
TIGRFAMsiTIGR00456 argS, 1 hit
PROSITEiView protein in PROSITE
PS00178 AA_TRNA_LIGASE_I, 1 hit

Sequencei

Sequence statusi: Complete.

A4XPN9-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MKDSIRHLIQ QALDRLTADG VLPAGLTPAI QVENTKDKSH GDFASNIAMM
60 70 80 90 100
LAKPAGMKPR DLAEKLIAAL PADAGIAKVE IAGPGFLNFF QNSDALAQRL
110 120 130 140 150
EAALADAQLG VHKNGPAQRV VVDLSAPNLA KEMHVGHLRS TIIGDGVARV
160 170 180 190 200
LEFLGDTVIR QNHVGDWGTQ FGMLLAYMQE NPAAAESELA DLEGFYRAAK
210 220 230 240 250
KRFDESPEFA DRARELVVQL QAGDAECLRL WHRFNDISLS HCQALYDRLG
260 270 280 290 300
VKLSMADVKG ESAYNDDLPQ VVADLAAKGL LTEDNGAQCV FMDEFKNAEG
310 320 330 340 350
NPLPLIVQKA GGGYLYATTD LAATRYRAGV LKADRVLYFV DQRQALHFQM
360 370 380 390 400
VFACARLAGF VPASMELEHM GFGTMNGPDG RPFKTRDGGT VKLVQLLDEA
410 420 430 440 450
EQRAYELVKS KNPELAEDEL RRIARVVGIA SVKYADLSKH RASDYSFNFD
460 470 480 490 500
LMLSFEGNTA PYLLYAYTRV AGVFRKLGKG IDEIGGRIAL VAEQEQALAA
510 520 530 540 550
KLAQFGELLA SVADKGTPHM LCSYLYDLAG LFSSFYENCP ILAAEDEATR
560 570
DSRLRLTALT GRTLKQGLEL LGLETLERM
Length:579
Mass (Da):63,275
Last modified:May 29, 2007 - v1
Checksum:iE8DAC4CBB19C3012
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP000680 Genomic DNA Translation: ABP83305.1
RefSeqiWP_011920754.1, NC_009439.1

Genome annotation databases

EnsemblBacteriaiABP83305; ABP83305; Pmen_0535
GeneIDi5108159
KEGGipmy:Pmen_0535
PATRICifig|399739.8.peg.543

Similar proteinsi

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP000680 Genomic DNA Translation: ABP83305.1
RefSeqiWP_011920754.1, NC_009439.1

3D structure databases

ProteinModelPortaliA4XPN9
SMRiA4XPN9
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi399739.Pmen_0535

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiABP83305; ABP83305; Pmen_0535
GeneIDi5108159
KEGGipmy:Pmen_0535
PATRICifig|399739.8.peg.543

Phylogenomic databases

eggNOGiENOG4105C75 Bacteria
COG0018 LUCA
HOGENOMiHOG000247212
KOiK01887
OMAiNKPLHLG
OrthoDBiPOG091H01RF

Enzyme and pathway databases

BioCyciPMEN399739:PMEN_RS02650-MONOMER

Family and domain databases

CDDicd00671 ArgRS_core, 1 hit
Gene3Di3.30.1360.70, 1 hit
3.40.50.620, 1 hit
HAMAPiMF_00123 Arg_tRNA_synth, 1 hit
InterProiView protein in InterPro
IPR001412 aa-tRNA-synth_I_CS
IPR001278 Arg-tRNA-ligase
IPR005148 Arg-tRNA-synth_N
IPR036695 Arg-tRNA-synth_N_sf
IPR035684 ArgRS_core
IPR008909 DALR_anticod-bd
IPR014729 Rossmann-like_a/b/a_fold
IPR009080 tRNAsynth_Ia_anticodon-bd
PANTHERiPTHR11956 PTHR11956, 1 hit
PfamiView protein in Pfam
PF03485 Arg_tRNA_synt_N, 1 hit
PF05746 DALR_1, 1 hit
PF00750 tRNA-synt_1d, 1 hit
PRINTSiPR01038 TRNASYNTHARG
SMARTiView protein in SMART
SM01016 Arg_tRNA_synt_N, 1 hit
SM00836 DALR_1, 1 hit
SUPFAMiSSF47323 SSF47323, 1 hit
SSF55190 SSF55190, 1 hit
TIGRFAMsiTIGR00456 argS, 1 hit
PROSITEiView protein in PROSITE
PS00178 AA_TRNA_LIGASE_I, 1 hit
ProtoNetiSearch...

Entry informationi

Entry nameiSYR_PSEMY
AccessioniPrimary (citable) accession number: A4XPN9
Entry historyiIntegrated into UniProtKB/Swiss-Prot: January 15, 2008
Last sequence update: May 29, 2007
Last modified: October 10, 2018
This is version 71 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families
  2. Aminoacyl-tRNA synthetases
    List of aminoacyl-tRNA synthetase entries
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Main funding by: National Institutes of Health

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