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Protein

tRNA pseudouridine synthase A

Gene

truA

Organism
Salinispora tropica (strain ATCC BAA-916 / DSM 44818 / CNB-440)
Status
Unreviewed-Annotation score: -Protein inferred from homologyi

Functioni

Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs.UniRule annotationSAAS annotation

Caution

Lacks conserved residue(s) required for the propagation of feature annotation.UniRule annotation

Catalytic activityi

tRNA uridine(38-40) = tRNA pseudouridine(38-40).UniRule annotationSAAS annotation

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Active sitei57NucleophileUniRule annotation1
Binding sitei118SubstrateUniRule annotation1

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionIsomeraseUniRule annotationSAAS annotationImported
Biological processtRNA processingUniRule annotationSAAS annotation

Names & Taxonomyi

Protein namesi
Recommended name:
tRNA pseudouridine synthase AUniRule annotation (EC:5.4.99.12UniRule annotation)
Alternative name(s):
tRNA pseudouridine(38-40) synthaseUniRule annotation
tRNA pseudouridylate synthase IUniRule annotation
tRNA-uridine isomerase IUniRule annotation
Gene namesi
Name:truAUniRule annotation
Ordered Locus Names:Strop_3893Imported
OrganismiSalinispora tropica (strain ATCC BAA-916 / DSM 44818 / CNB-440)Imported
Taxonomic identifieri369723 [NCBI]
Taxonomic lineageiBacteriaActinobacteriaMicromonosporalesMicromonosporaceaeSalinispora
Proteomesi
  • UP000000235 Componenti: Chromosome

Interactioni

Subunit structurei

Homodimer.UniRule annotation

Protein-protein interaction databases

STRINGi369723.Strop_3893

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini152 – 254PseudoU_synth_1InterPro annotationAdd BLAST103

Sequence similaritiesi

Belongs to the tRNA pseudouridine synthase TruA family.UniRule annotationSAAS annotation

Phylogenomic databases

eggNOGiENOG4105DI7 Bacteria
COG0101 LUCA
HOGENOMiHOG000248674
KOiK06173
OMAiFLYGMVR
OrthoDBiPOG091H010Q

Family and domain databases

Gene3Di3.30.70.660, 1 hit
HAMAPiMF_00171 TruA, 1 hit
InterProiView protein in InterPro
IPR020103 PsdUridine_synth_cat_dom_sf
IPR001406 PsdUridine_synth_TruA
IPR020097 PsdUridine_synth_TruA_a/b_dom
IPR020095 PsdUridine_synth_TruA_C
PANTHERiPTHR11142 PTHR11142, 1 hit
PfamiView protein in Pfam
PF01416 PseudoU_synth_1, 1 hit
PIRSFiPIRSF001430 tRNA_psdUrid_synth, 1 hit
SUPFAMiSSF55120 SSF55120, 1 hit
TIGRFAMsiTIGR00071 hisT_truA, 1 hit

Sequencei

Sequence statusi: Complete.

A4XBL6-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MQERTRVRLD VSYDGADFSG WAVQPERRTV AGALVQALDL VLGVGAATGL
60 70 80 90 100
TVAGRTDAGV HATGQVCHVD LLTEVWHRHE HTLLRRLARL LPADVRIRAM
110 120 130 140 150
TEAPDDFDAR FSATFRRYEY RVTDAPWGAE PLRRHDTLAW PSRLDLAALN
160 170 180 190 200
VAADGLVGEH DFAAYCRRKE NATTLREVTR LEWRRAPDGT LVATVQADAF
210 220 230 240 250
CQAMVRSLVG AMLAVGDGRR PADWPAGLLT RRERASEVNV APAHGLTLVA
260 270
VGYPDDPSEY ARRATLTRRL RVPPQA
Length:276
Mass (Da):30,490
Last modified:May 29, 2007 - v1
Checksum:i43A1BAEA96D5B342
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP000667 Genomic DNA Translation: ABP56323.1
RefSeqiWP_012015098.1, NC_009380.1

Genome annotation databases

EnsemblBacteriaiABP56323; ABP56323; Strop_3893
GeneIDi5060371
KEGGistp:Strop_3893
PATRICifig|369723.5.peg.4018

Similar proteinsi

Entry informationi

Entry nameiA4XBL6_SALTO
AccessioniPrimary (citable) accession number: A4XBL6
Entry historyiIntegrated into UniProtKB/TrEMBL: May 29, 2007
Last sequence update: May 29, 2007
Last modified: July 18, 2018
This is version 88 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported

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