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Protein

Met repressor

Gene

metJ

Organism
Enterobacter sp. (strain 638)
Status
Reviewed-Annotation score: -Protein inferred from homologyi

Functioni

This regulatory protein, when combined with SAM (S-adenosylmethionine) represses the expression of the methionine regulon and of enzymes involved in SAM synthesis.UniRule annotation

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionDNA-binding, Repressor
Biological processAmino-acid biosynthesis, Methionine biosynthesis, Transcription, Transcription regulation

Names & Taxonomyi

Protein namesi
Recommended name:
Met repressorUniRule annotation
Alternative name(s):
Met regulon regulatory protein MetJUniRule annotation
Gene namesi
Name:metJUniRule annotation
Ordered Locus Names:Ent638_4036
OrganismiEnterobacter sp. (strain 638)
Taxonomic identifieri399742 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaEnterobacteralesEnterobacteriaceaeEnterobacter
Proteomesi
  • UP000000230 Componenti: Chromosome

Subcellular locationi

GO - Cellular componenti

Keywords - Cellular componenti

Cytoplasm

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_10000621721 – 105Met repressorAdd BLAST105

Interactioni

Subunit structurei

Homodimer.UniRule annotation

Protein-protein interaction databases

STRINGi399742.Ent638_4036

Structurei

3D structure databases

ProteinModelPortaliA4WG61
SMRiA4WG61
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domaini

Does not bind DNA by a helix-turn-helix motif.

Sequence similaritiesi

Belongs to the MetJ family.UniRule annotation

Phylogenomic databases

eggNOGiENOG4105GGQ Bacteria
COG3060 LUCA
HOGENOMiHOG000271582
KOiK03764
OMAiKWNGEYI

Family and domain databases

CDDicd00490 Met_repressor_MetJ, 1 hit
Gene3Di1.10.140.10, 1 hit
HAMAPiMF_00744 MetJ, 1 hit
InterProiView protein in InterPro
IPR002084 Met_repressor_MetJ
IPR023453 Met_repressor_MetJ_dom_sf
IPR010985 Ribbon_hlx_hlx
PfamiView protein in Pfam
PF01340 MetJ, 1 hit
ProDomiView protein in ProDom or Entries sharing at least one domain
PD020365 Met_repressor_MetJ, 1 hit
SUPFAMiSSF47598 SSF47598, 1 hit

Sequencei

Sequence statusi: Complete.

A4WG61-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MAEWSGEYIS PYAEHGKKSE QVKKITVSIP LKVLKILTDE RTRRQVNNLR
60 70 80 90 100
HATNSELLCE AFLHAFTGQP LPNDEDLRKE RSDEIPEAAK VIMRELGIDP

DTWEY
Length:105
Mass (Da):12,137
Last modified:May 29, 2007 - v1
Checksum:i617F50A919768AD0
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP000653 Genomic DNA Translation: ABP62691.1
RefSeqiWP_015960995.1, NC_009436.1

Genome annotation databases

EnsemblBacteriaiABP62691; ABP62691; Ent638_4036
GeneIDi32445121
KEGGient:Ent638_4036

Similar proteinsi

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP000653 Genomic DNA Translation: ABP62691.1
RefSeqiWP_015960995.1, NC_009436.1

3D structure databases

ProteinModelPortaliA4WG61
SMRiA4WG61
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi399742.Ent638_4036

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiABP62691; ABP62691; Ent638_4036
GeneIDi32445121
KEGGient:Ent638_4036

Phylogenomic databases

eggNOGiENOG4105GGQ Bacteria
COG3060 LUCA
HOGENOMiHOG000271582
KOiK03764
OMAiKWNGEYI

Family and domain databases

CDDicd00490 Met_repressor_MetJ, 1 hit
Gene3Di1.10.140.10, 1 hit
HAMAPiMF_00744 MetJ, 1 hit
InterProiView protein in InterPro
IPR002084 Met_repressor_MetJ
IPR023453 Met_repressor_MetJ_dom_sf
IPR010985 Ribbon_hlx_hlx
PfamiView protein in Pfam
PF01340 MetJ, 1 hit
ProDomiView protein in ProDom or Entries sharing at least one domain
PD020365 Met_repressor_MetJ, 1 hit
SUPFAMiSSF47598 SSF47598, 1 hit
ProtoNetiSearch...

Entry informationi

Entry nameiMETJ_ENT38
AccessioniPrimary (citable) accession number: A4WG61
Entry historyiIntegrated into UniProtKB/Swiss-Prot: February 5, 2008
Last sequence update: May 29, 2007
Last modified: October 10, 2018
This is version 75 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families
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Main funding by: National Institutes of Health

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