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Protein

tRNA pseudouridine synthase D

Gene

truD

Organism
Pseudomonas stutzeri (strain A1501)
Status
Reviewed-Annotation score: -Protein inferred from homologyi

Functioni

Responsible for synthesis of pseudouridine from uracil-13 in transfer RNAs.UniRule annotation

Catalytic activityi

tRNA uridine(13) = tRNA pseudouridine(13).UniRule annotation

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Active sitei81NucleophileUniRule annotation1

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionIsomerase
Biological processtRNA processing

Enzyme and pathway databases

BioCyciPSTU379731:G1G6D-1613-MONOMER

Names & Taxonomyi

Protein namesi
Recommended name:
tRNA pseudouridine synthase DUniRule annotation (EC:5.4.99.27UniRule annotation)
Alternative name(s):
tRNA pseudouridine(13) synthaseUniRule annotation
tRNA pseudouridylate synthase DUniRule annotation
tRNA-uridine isomerase DUniRule annotation
Gene namesi
Name:truDUniRule annotation
Ordered Locus Names:PST_1567
OrganismiPseudomonas stutzeri (strain A1501)
Taxonomic identifieri379731 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaPseudomonadalesPseudomonadaceaePseudomonas
Proteomesi
  • UP000000233 Componenti: Chromosome

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_10000847601 – 346tRNA pseudouridine synthase DAdd BLAST346

Proteomic databases

PRIDEiA4VJV1

Interactioni

Protein-protein interaction databases

STRINGi379731.PST_1567

Structurei

3D structure databases

ProteinModelPortaliA4VJV1
SMRiA4VJV1
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini157 – 303TRUDUniRule annotationAdd BLAST147

Sequence similaritiesi

Belongs to the pseudouridine synthase TruD family.UniRule annotation

Phylogenomic databases

eggNOGiENOG4106NZV Bacteria
COG0585 LUCA
HOGENOMiHOG000224848
KOiK06176
OMAiGNRFFMR
OrthoDBiPOG091H03KK

Family and domain databases

HAMAPiMF_01082 TruD, 1 hit
InterProiView protein in InterPro
IPR020103 PsdUridine_synth_cat_dom_sf
IPR001656 PsdUridine_synth_TruD
IPR020119 PsdUridine_synth_TruD_CS
IPR011760 PsdUridine_synth_TruD_insert
PANTHERiPTHR13326 PTHR13326, 2 hits
PfamiView protein in Pfam
PF01142 TruD, 2 hits
SUPFAMiSSF55120 SSF55120, 1 hit
PROSITEiView protein in PROSITE
PS50984 TRUD, 1 hit
PS01268 UPF0024, 1 hit

Sequencei

Sequence statusi: Complete.

A4VJV1-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MTEDQLLGPR AHGEPCGSAV LKAVAEDFQV EEVLDIPLSG EGEHLWLWVE
60 70 80 90 100
KRNLNTEEAA KRIARAAGVP LKLISYAGLK DRQALTRQWF SLHLPGKADP
110 120 130 140 150
DLAAAEDDSL RLLQRVRHQR KLQRGAHSAN GFRLRLTDLH ADHAQLDARL
160 170 180 190 200
ERIRAQGVPN YFGLQRFGYE GGNLLGARDF AARAELPVQR NLRSRLLSAG
210 220 230 240 250
RSYLFNRVLA QRVADGSWAE ARVGDLLAFT DSRSFFPAAE AECSDPRLAI
260 270 280 290 300
LDLHPTGPLW GEGGSPAGAE IQALEDAVAA SEEPIANWLA QAGMKHERRI
310 320 330 340
LRLPIGGLSW HYPGPDILQL EFVLPTGCFA TAMVRELVSL AGQTDI
Length:346
Mass (Da):38,060
Last modified:May 29, 2007 - v1
Checksum:iB6D3C2B164E7097F
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP000304 Genomic DNA Translation: ABP79252.1
RefSeqiWP_011912730.1, NC_009434.1

Genome annotation databases

EnsemblBacteriaiABP79252; ABP79252; PST_1567
KEGGipsa:PST_1567

Similar proteinsi

Entry informationi

Entry nameiTRUD_PSEU5
AccessioniPrimary (citable) accession number: A4VJV1
Entry historyiIntegrated into UniProtKB/Swiss-Prot: May 20, 2008
Last sequence update: May 29, 2007
Last modified: September 12, 2018
This is version 72 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health

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