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Entry version 119 (02 Jun 2021)
Sequence version 1 (29 May 2007)
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Protein
Submitted name:

Brother of odd with entrails limited, isoform B

Gene

bowl

Organism
Drosophila melanogaster (Fruit fly)
Status
Unreviewed-Annotation score:

Annotation score:2 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Protein predictedi <p>This indicates the type of evidence that supports the existence of the protein. Note that the 'protein existence' evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywordsi

LigandMetal-binding, Zinc

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Submitted name:
Brother of odd with entrails limited, isoform BImported
Submitted name:
Brother of odd with entrails limited, isoform CImported
Submitted name:
Brother of odd with entrails limited, isoform DImported
Submitted name:
Brother of odd with entrails limited, isoform FImported
Submitted name:
Brother of odd with entrails limited, isoform GImported
Submitted name:
Brother of odd with entrails limited, isoform HImported
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: 'Name', 'Synonyms', 'Ordered locus names' and 'ORF names'.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:bowlImported
Synonyms:17-29-5Imported, BOWLImported, BowlImported, Dmel\CG10021Imported, l(2)cImported, org2Imported, Su(tor)2-1Imported
ORF Names:CG10021Imported, Dmel_CG10021Imported
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiDrosophila melanogaster (Fruit fly)Imported
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the 'taxonomic identifier' or 'taxid'.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri7227 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryotaMetazoaEcdysozoaArthropodaHexapodaInsectaPterygotaNeopteraEndopterygotaDipteraBrachyceraMuscomorphaEphydroideaDrosophilidaeDrosophilaSophophora
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000000803 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes%5Fmanual">proteome</a> can consist of several components.<br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome 2L

Organism-specific databases

Drosophila genome database

More...
FlyBasei
FBgn0004893, bowl

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

Gene expression databases

Bgee dataBase for Gene Expression Evolution

More...
Bgeei
FBgn0004893, Expressed in wing disc (Drosophila) and 73 other tissues

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/family%5Fand%5Fdomains%5Fsection">Family and Domains</a> section describes the position and type of a domain, which is defined as a specific combination of secondary structures organized into a characteristic three-dimensional structure or fold.<p><a href='/help/domain' target='_top'>More...</a></p>Domaini238 – 265C2H2-typeInterPro annotationAdd BLAST28
Domaini266 – 293C2H2-typeInterPro annotationAdd BLAST28
Domaini294 – 321C2H2-typeInterPro annotationAdd BLAST28
Domaini322 – 349C2H2-typeInterPro annotationAdd BLAST28
Domaini350 – 373C2H2-typeInterPro annotationAdd BLAST24

Region

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Family and Domains' section describes a region of interest that cannot be described in other subsections.<p><a href='/help/region' target='_top'>More...</a></p>Regioni1 – 24DisorderedSequence analysisAdd BLAST24
Regioni38 – 77DisorderedSequence analysisAdd BLAST40
Regioni391 – 593DisorderedSequence analysisAdd BLAST203
Regioni608 – 648DisorderedSequence analysisAdd BLAST41
Regioni686 – 744DisorderedSequence analysisAdd BLAST59

Compositional bias

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Family and Domains' section describes the position of regions of compositional bias within the protein and the particular type of amino acids that are over-represented within those regions.<p><a href='/help/compbias' target='_top'>More...</a></p>Compositional biasi56 – 77Polar residuesSequence analysisAdd BLAST22
Compositional biasi391 – 405Basic and acidic residuesSequence analysisAdd BLAST15
Compositional biasi423 – 442Basic and acidic residuesSequence analysisAdd BLAST20
Compositional biasi493 – 510Polar residuesSequence analysisAdd BLAST18
Compositional biasi512 – 537Basic and acidic residuesSequence analysisAdd BLAST26
Compositional biasi559 – 589Pro residuesSequence analysisAdd BLAST31
Compositional biasi614 – 628Pro residuesSequence analysisAdd BLAST15
Compositional biasi719 – 733Pro residuesSequence analysisAdd BLAST15

Keywords - Domaini

Zinc-fingerPROSITE-ProRule annotation

Phylogenomic databases

The HOGENOM Database of Homologous Genes from Fully Sequenced Organisms

More...
HOGENOMi
CLU_015566_0_0_1

Identification of Orthologs from Complete Genome Data

More...
OMAi
HREISAF

Database of Orthologous Groups

More...
OrthoDBi
1318335at2759

Family and domain databases

Integrated resource of protein families, domains and functional sites

More...
InterProi
View protein in InterPro
IPR036236, Znf_C2H2_sf
IPR013087, Znf_C2H2_type

Pfam protein domain database

More...
Pfami
View protein in Pfam
PF00096, zf-C2H2, 5 hits

Simple Modular Architecture Research Tool; a protein domain database

More...
SMARTi
View protein in SMART
SM00355, ZnF_C2H2, 5 hits

Superfamily database of structural and functional annotation

More...
SUPFAMi
SSF57667, SSF57667, 3 hits

PROSITE; a protein domain and family database

More...
PROSITEi
View protein in PROSITE
PS00028, ZINC_FINGER_C2H2_1, 5 hits
PS50157, ZINC_FINGER_C2H2_2, 5 hits

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence%5Flength">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequence (1+)i

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences%5Fsection">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

This entry has 1 described isoform and 1 potential isoform that is computationally mapped.Show allAlign All

A4V047-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MPTESSSSEI SGGGGGAIPM LRPSRMDQFM NSMAAAAAAV GGGGLPGAAD
60 70 80 90 100
RNGGSGGSDG GSQNGNGDSR NSSASRISAY ETQLAYQQHL AGLHGPPPPP
110 120 130 140 150
PPSHHREISA FVPVLPTGKV RPGSNSNYEI IAMMADKRKE LALREAAAAA
160 170 180 190 200
AMLGRGPGGP GGPGVPPPGV LYGPAGVPPP PYLTGPGPSP TGAGSFPFPP
210 220 230 240 250
GAAAAALFPP GLGPGMHAGL DRRLLRAPGR ASRPKKQFIC KFCNRQFTKS
260 270 280 290 300
YNLLIHERTH TDERPYSCDI CGKAFRRQDH LRDHRYIHSK EKPFKCTECG
310 320 330 340 350
KGFCQSRTLA VHKILHMEES PHKCPVCSRS FNQRSNLKTH LLTHTDHKPY
360 370 380 390 400
ECSSCGKVFR RNCDLRRHAL THAVGEVNSG DYVDVGEEDE ARNLSGDEED
410 420 430 440 450
SLLEVDSPRQ SPVHNLGESG GSGEKSESER MRLKRKAAID HEESEEEFDD
460 470 480 490 500
FDEEEELQDL PRVHDLPREE DDDFDPEDEE QAEVALVARF QASKAAATSQ
510 520 530 540 550
SSSSVGTKPE RQGVTHCHHE GGETYTMRPH GEKHQEEPGN SGIASLPVPP
560 570 580 590 600
SFVRYSVPPG AAGPPPAPPG APPPTHQHPG HPHLLPPNGD PYLPILHVRR
610 620 630 640 650
DLHHKSLNLS KAGVPPPPHT PPTIITQPES GKPPNQPLHS PHEAMPSFLG
660 670 680 690 700
SIPMRKRILP APTLDLMDPH HHPGLGQRTF VDSPSIYALN MSRHPPRQLL
710 720 730 740
GKPPSTETSG ATTEKGPPVA APPIAPPPAP PRRTGFSIED IMRR
Length:744
Mass (Da):79,831
Last modified:May 29, 2007 - v1
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:i403653CE7F57672D
GO

<p>In eukaryotic reference proteomes, unreviewed entries that are likely to belong to the same gene are computationally mapped, based on gene identifiers from Ensembl, EnsemblGenomes and model organism databases.<p><a href='/help/gene_centric_isoform_mapping' target='_top'>More...</a></p>Computationally mapped potential isoform sequencesi

There is 1 potential isoform mapped to this entry.BLASTAlignShow allAdd to basket
EntryEntry nameProtein names
Gene namesLengthAnnotation
Q9VQU9BOWEL_DROME
Protein bowel
bowl CG10021
744Annotation score:

Annotation score:5 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...
EMBLi

GenBank nucleotide sequence database

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GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...
DDBJi
Links Updated
AE014134 Genomic DNA Translation: AAF51063.1
AE014134 Genomic DNA Translation: AAF51064.1
AE014134 Genomic DNA Translation: AAN10360.1
AE014134 Genomic DNA Translation: AFH03537.1
AE014134 Genomic DNA Translation: AFH03538.1
AE014134 Genomic DNA Translation: AFH03539.1

NCBI Reference Sequences

More...
RefSeqi
NP_001245861.1, NM_001258932.2
NP_001245862.1, NM_001258933.2
NP_001245863.1, NM_001258934.1
NP_476883.1, NM_057535.4
NP_722939.1, NM_164556.2
NP_722940.1, NM_164557.3
NP_722941.1, NM_164558.2

Genome annotation databases

Ensembl metazoan genome annotation project

More...
EnsemblMetazoai
FBtr0077490; FBpp0077179; FBgn0004893
FBtr0077491; FBpp0077180; FBgn0004893
FBtr0077492; FBpp0077181; FBgn0004893
FBtr0077493; FBpp0077182; FBgn0004893
FBtr0307027; FBpp0297870; FBgn0004893
FBtr0307028; FBpp0297871; FBgn0004893
FBtr0307029; FBpp0297872; FBgn0004893

Database of genes from NCBI RefSeq genomes

More...
GeneIDi
33602

KEGG: Kyoto Encyclopedia of Genes and Genomes

More...
KEGGi
dme:Dmel_CG10021

UCSC genome browser

More...
UCSCi
CG10021-RB, d. melanogaster

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AE014134 Genomic DNA Translation: AAF51063.1
AE014134 Genomic DNA Translation: AAF51064.1
AE014134 Genomic DNA Translation: AAN10360.1
AE014134 Genomic DNA Translation: AFH03537.1
AE014134 Genomic DNA Translation: AFH03538.1
AE014134 Genomic DNA Translation: AFH03539.1
RefSeqiNP_001245861.1, NM_001258932.2
NP_001245862.1, NM_001258933.2
NP_001245863.1, NM_001258934.1
NP_476883.1, NM_057535.4
NP_722939.1, NM_164556.2
NP_722940.1, NM_164557.3
NP_722941.1, NM_164558.2

3D structure databases

Database of comparative protein structure models

More...
ModBasei
Search...

SWISS-MODEL Interactive Workspace

More...
SWISS-MODEL-Workspacei
Submit a new modelling project...

Protocols and materials databases

The DNASU plasmid repository

More...
DNASUi
33602

Genome annotation databases

EnsemblMetazoaiFBtr0077490; FBpp0077179; FBgn0004893
FBtr0077491; FBpp0077180; FBgn0004893
FBtr0077492; FBpp0077181; FBgn0004893
FBtr0077493; FBpp0077182; FBgn0004893
FBtr0307027; FBpp0297870; FBgn0004893
FBtr0307028; FBpp0297871; FBgn0004893
FBtr0307029; FBpp0297872; FBgn0004893
GeneIDi33602
KEGGidme:Dmel_CG10021
UCSCiCG10021-RB, d. melanogaster

Organism-specific databases

Comparative Toxicogenomics Database

More...
CTDi
33602
FlyBaseiFBgn0004893, bowl

Phylogenomic databases

HOGENOMiCLU_015566_0_0_1
OMAiHREISAF
OrthoDBi1318335at2759

Miscellaneous databases

BioGRID ORCS database of CRISPR phenotype screens

More...
BioGRID-ORCSi
33602, 0 hits in 3 CRISPR screens

Database of phenotypes from RNA interference screens in Drosophila and Homo sapiens

More...
GenomeRNAii
33602

Gene expression databases

BgeeiFBgn0004893, Expressed in wing disc (Drosophila) and 73 other tissues

Family and domain databases

InterProiView protein in InterPro
IPR036236, Znf_C2H2_sf
IPR013087, Znf_C2H2_type
PfamiView protein in Pfam
PF00096, zf-C2H2, 5 hits
SMARTiView protein in SMART
SM00355, ZnF_C2H2, 5 hits
SUPFAMiSSF57667, SSF57667, 3 hits
PROSITEiView protein in PROSITE
PS00028, ZINC_FINGER_C2H2_1, 5 hits
PS50157, ZINC_FINGER_C2H2_2, 5 hits

MobiDB: a database of protein disorder and mobility annotations

More...
MobiDBi
Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the 'Entry information' section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiA4V047_DROME
<p>This subsection of the 'Entry information' section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called 'Primary (citable) accession number'.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: A4V047
<p>This subsection of the 'Entry information' section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification ('Last modified'). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/TrEMBL: May 29, 2007
Last sequence update: May 29, 2007
Last modified: June 2, 2021
This is version 119 of the entry and version 1 of the sequence. See complete history.
<p>This subsection of the 'Entry information' section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiUnreviewed (UniProtKB/TrEMBL)

<p>This section contains any relevant information that doesn't fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Reference proteomeImported
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