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Protein

Altronate oxidoreductase

Gene

uxaB

Organism
Yersinia pestis (strain Pestoides F)
Status
Reviewed-Annotation score: -Protein inferred from homologyi

Functioni

Catalytic activityi

D-altronate + NAD+ = D-tagaturonate + NADH.UniRule annotation

Pathwayi: pentose and glucuronate interconversion

This protein is involved in the pathway pentose and glucuronate interconversion, which is part of Carbohydrate metabolism.UniRule annotation
View all proteins of this organism that are known to be involved in the pathway pentose and glucuronate interconversion and in Carbohydrate metabolism.

Regions

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Nucleotide bindingi18 – 29NADUniRule annotationAdd BLAST12

GO - Molecular functioni

Keywordsi

Molecular functionOxidoreductase
LigandNAD

Enzyme and pathway databases

UniPathwayiUPA00246

Names & Taxonomyi

Protein namesi
Recommended name:
Altronate oxidoreductaseUniRule annotation (EC:1.1.1.58UniRule annotation)
Alternative name(s):
Tagaturonate dehydrogenaseUniRule annotation
Tagaturonate reductaseUniRule annotation
Gene namesi
Name:uxaBUniRule annotation
Ordered Locus Names:YPDSF_0367
OrganismiYersinia pestis (strain Pestoides F)
Taxonomic identifieri386656 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaEnterobacteralesYersiniaceaeYersinia

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_10000447111 – 483Altronate oxidoreductaseAdd BLAST483

Structurei

3D structure databases

ProteinModelPortaliA4THM0
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the mannitol dehydrogenase family. UxaB subfamily.UniRule annotation

Phylogenomic databases

HOGENOMiHOG000029586
KOiK00041
OMAiVVIVRPI

Family and domain databases

Gene3Di1.10.1040.10, 1 hit
HAMAPiMF_00670 Altron_oxidoreduct, 1 hit
InterProiView protein in InterPro
IPR008927 6-PGluconate_DH-like_C_sf
IPR013328 6PGD_dom2
IPR023668 Altronate_OxRdtase
IPR013118 Mannitol_DH_C
IPR013131 Mannitol_DH_N
IPR036291 NAD(P)-bd_dom_sf
PfamiView protein in Pfam
PF01232 Mannitol_dh, 1 hit
PF08125 Mannitol_dh_C, 1 hit
SUPFAMiSSF48179 SSF48179, 1 hit
SSF51735 SSF51735, 1 hit

Sequencei

Sequence statusi: Complete.

A4THM0-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MQTLNRRDFP GRSHPDKIIQ FGEGNFLRAF VDWQIDLLNE HTDLNAGIVV
60 70 80 90 100
IRPIDTDFPP SLSTQDGLYT AVIRGLNEQG EAVRESRLIR SVNREINIYR
110 120 130 140 150
QFDDYLALAR DANIRFMFSN TTEAGIAWNE ADQFSDAPPS SFPAKLTRLL
160 170 180 190 200
FERFEHFDGA ADKGWVLLPC ELIDYNGEAL RELVLRYASH WQLPAAFTHW
210 220 230 240 250
LTENNTFCST LVDRIVTGYP RDEVAALQTE LGYQDSFLDT AEYFYLFVIQ
260 270 280 290 300
GPQGLAQELR LDQLDLNVRI VDDIKPYKER KVAILNGAHT ALVPVAYLSG
310 320 330 340 350
LDTVGQTMDD AQISRFVEKT ITEEIVPVLD LPEDELLSFS QAVLSRFRNP
360 370 380 390 400
FIQHQLLSIA LNGMTKFRTR ILPQLLTYQQ QKGQLPPRLT FALAALIAFY
410 420 430 440 450
RGEREGQTYP LQDDAHWLER YSTLWNGVKH GDIALAELVN RVLSDANHWG
460 470 480
QDLTAVPQLA NQVTEQLQTI LSRGMRAAVA AYS
Length:483
Mass (Da):54,907
Last modified:May 15, 2007 - v1
Checksum:iBDDB13837F6564B4
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP000668 Genomic DNA Translation: ABP38782.1
RefSeqiWP_002210409.1, NZ_CP009715.1

Genome annotation databases

EnsemblBacteriaiABP38782; ABP38782; YPDSF_0367
KEGGiypp:YPDSF_0367
PATRICifig|386656.14.peg.1670

Similar proteinsi

Entry informationi

Entry nameiUXAB_YERPP
AccessioniPrimary (citable) accession number: A4THM0
Entry historyiIntegrated into UniProtKB/Swiss-Prot: January 15, 2008
Last sequence update: May 15, 2007
Last modified: November 22, 2017
This is version 69 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Documents

  1. PATHWAY comments
    Index of metabolic and biosynthesis pathways
  2. SIMILARITY comments
    Index of protein domains and families

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