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Protein
Submitted name:

Proto-oncogene c-Rel

Gene

Rel

Organism
Mus musculus (Mouse)
Status
Unreviewed-Annotation score: -Experimental evidence at protein leveli

Functioni

GO - Molecular functioni

GO - Biological processi

Enzyme and pathway databases

ReactomeiR-MMU-1169091 Activation of NF-kappaB in B cells

Names & Taxonomyi

Protein namesi
Submitted name:
Proto-oncogene c-RelImported
Submitted name:
Reticuloendotheliosis oncogeneImported
Gene namesi
Name:RelImported
ORF Names:mCG_8770Imported
OrganismiMus musculus (Mouse)Imported
Taxonomic identifieri10090 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaMyomorphaMuroideaMuridaeMurinaeMusMus
Proteomesi
  • UP000000589 Componenti: Chromosome 11

Organism-specific databases

MGIiMGI:97897 Rel

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Expressioni

Gene expression databases

BgeeiENSMUSG00000020275 Expressed in 190 organ(s), highest expression level in mesenteric lymph node

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini5 – 182RHDInterPro annotationAdd BLAST178

Phylogenomic databases

eggNOGiENOG410IG8F Eukaryota
ENOG410XT64 LUCA
GeneTreeiENSGT00500000044765
HOGENOMiHOG000264257
HOVERGENiHBG017916
KOiK09254
OMAiLLFQKLW
OrthoDBiEOG091G08JD
TreeFamiTF325632

Family and domain databases

CDDicd01177 IPT_NFkappaB, 1 hit
Gene3Di2.60.40.10, 1 hit
2.60.40.340, 1 hit
InterProiView protein in InterPro
IPR030505 c-Rel
IPR013783 Ig-like_fold
IPR014756 Ig_E-set
IPR002909 IPT_dom
IPR033926 IPT_NFkappaB
IPR000451 NFkB/Dor
IPR008967 p53-like_TF_DNA-bd
IPR030492 RHD_CS
IPR032397 RHD_dimer
IPR011539 RHD_DNA_bind_dom
IPR037059 RHD_DNA_bind_dom_sf
PANTHERiPTHR24169 PTHR24169, 1 hit
PTHR24169:SF4 PTHR24169:SF4, 1 hit
PfamiView protein in Pfam
PF16179 RHD_dimer, 1 hit
PF00554 RHD_DNA_bind, 1 hit
PRINTSiPR00057 NFKBTNSCPFCT
SMARTiView protein in SMART
SM00429 IPT, 1 hit
SUPFAMiSSF49417 SSF49417, 1 hit
SSF81296 SSF81296, 1 hit
PROSITEiView protein in PROSITE
PS01204 REL_1, 1 hit
PS50254 REL_2, 1 hit

Sequence (1+)i

Sequence statusi: Complete.

This entry has 1 described isoform and 1 potential isoform that is computationally mapped.Show allAlign All

A4QPD3-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MASSGYNPYV EIIEQPRQRG MRFRYKCEGR SAGSIPGERS TDNNRTYPSV
60 70 80 90 100
QIMNYYGKGK IRITLVTKND PYKPHPHDLV GKDCRDGYYE AEFGPERRPL
110 120 130 140 150
FFQNLGIRCV KKKEVKEAII LRISAGINPF NVPEQQLLDI EDCDLNVVRL
160 170 180 190 200
CFQVFLPDEH GNFTTALPPI VSNPIYDNRA PNTAELRICR VNKNCGSVRG
210 220 230 240 250
GDEIFLLCDK VQKDDIEVRF VLNDWEARGV FSQADVHRQV AIVFKTPPYC
260 270 280 290 300
KAILEPVTVK MQLRRPSDQE VSESMDFRYL PDEKDAYGNK SKKQKTTLIF
310 320 330 340 350
QKLLQDCGHF TEKPRTAPLG STGEGRFIKK ESNLFSHGTV LPEMPRSSGV
360 370 380 390 400
PGQAEPYYSS CGSISSGLPH HPPAIPSVAH QPTSWPPVTH PTSHPVSTNT
410 420 430 440 450
LSTFSAGTLS SNSQGILPFL EGPGVSDLSA SNSCLYNPDD LARMETPSMS
460 470 480 490 500
PTDLYSISDV NMLSTRPLSV MAPSTDGMGD TDNPRLVSIN LENPSCNARL
510 520 530 540 550
GPRDLRQLHQ MSPASLSAGT SSSSVFVSQS DAFDRSNFSC VDNGLMNEPG
560 570 580
LSDDANNPTF VQSSHYSSVN TLQSEQLSDP FTYGFFKI
Length:588
Mass (Da):65,144
Last modified:February 5, 2008 - v1
Checksum:iD32CF1DF265F2AF6
GO

Computationally mapped potential isoform sequencesi

There is 1 potential isoform mapped to this entry.BLASTAlignShow allAdd to basket
EntryEntry nameProtein names
Gene namesLengthAnnotation
P15307REL_MOUSE
Proto-oncogene c-Rel
Rel
587Annotation score:

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AL805916 Genomic DNA No translation available.
BC139447 mRNA Translation: AAI39448.1
BC139448 mRNA Translation: AAI39449.1
BC139770 mRNA Translation: AAI39771.1
CH466595 Genomic DNA Translation: EDL07897.1
RefSeqiNP_033070.2, NM_009044.2
UniGeneiMm.4869

Genome annotation databases

EnsembliENSMUST00000102864; ENSMUSP00000099928; ENSMUSG00000020275
GeneIDi19696
KEGGimmu:19696
UCSCiuc007ifo.1 mouse

Similar proteinsi

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AL805916 Genomic DNA No translation available.
BC139447 mRNA Translation: AAI39448.1
BC139448 mRNA Translation: AAI39449.1
BC139770 mRNA Translation: AAI39771.1
CH466595 Genomic DNA Translation: EDL07897.1
RefSeqiNP_033070.2, NM_009044.2
UniGeneiMm.4869

3D structure databases

ModBaseiSearch...
MobiDBiSearch...

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENSMUST00000102864; ENSMUSP00000099928; ENSMUSG00000020275
GeneIDi19696
KEGGimmu:19696
UCSCiuc007ifo.1 mouse

Organism-specific databases

CTDi5966
MGIiMGI:97897 Rel

Phylogenomic databases

eggNOGiENOG410IG8F Eukaryota
ENOG410XT64 LUCA
GeneTreeiENSGT00500000044765
HOGENOMiHOG000264257
HOVERGENiHBG017916
KOiK09254
OMAiLLFQKLW
OrthoDBiEOG091G08JD
TreeFamiTF325632

Enzyme and pathway databases

ReactomeiR-MMU-1169091 Activation of NF-kappaB in B cells

Miscellaneous databases

ChiTaRSiRel mouse
SOURCEiSearch...

Gene expression databases

BgeeiENSMUSG00000020275 Expressed in 190 organ(s), highest expression level in mesenteric lymph node

Family and domain databases

CDDicd01177 IPT_NFkappaB, 1 hit
Gene3Di2.60.40.10, 1 hit
2.60.40.340, 1 hit
InterProiView protein in InterPro
IPR030505 c-Rel
IPR013783 Ig-like_fold
IPR014756 Ig_E-set
IPR002909 IPT_dom
IPR033926 IPT_NFkappaB
IPR000451 NFkB/Dor
IPR008967 p53-like_TF_DNA-bd
IPR030492 RHD_CS
IPR032397 RHD_dimer
IPR011539 RHD_DNA_bind_dom
IPR037059 RHD_DNA_bind_dom_sf
PANTHERiPTHR24169 PTHR24169, 1 hit
PTHR24169:SF4 PTHR24169:SF4, 1 hit
PfamiView protein in Pfam
PF16179 RHD_dimer, 1 hit
PF00554 RHD_DNA_bind, 1 hit
PRINTSiPR00057 NFKBTNSCPFCT
SMARTiView protein in SMART
SM00429 IPT, 1 hit
SUPFAMiSSF49417 SSF49417, 1 hit
SSF81296 SSF81296, 1 hit
PROSITEiView protein in PROSITE
PS01204 REL_1, 1 hit
PS50254 REL_2, 1 hit
ProtoNetiSearch...

Entry informationi

Entry nameiA4QPD3_MOUSE
AccessioniPrimary (citable) accession number: A4QPD3
Entry historyiIntegrated into UniProtKB/TrEMBL: February 5, 2008
Last sequence update: February 5, 2008
Last modified: November 7, 2018
This is version 96 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Proteomics identificationCombined sources, Reference proteomeImported
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health

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