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Protein

Beta-hexosaminidase

Gene

BmGlcNAcase1

Organism
Bombyx mori (Silk moth)
Status
Unreviewed-Annotation score: -Experimental evidence at transcript leveli

Functioni

Catalytic activityi

Hydrolysis of terminal non-reducing N-acetyl-D-hexosamine residues in N-acetyl-beta-D-hexosaminides.UniRule annotation

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Active sitei395Proton donorUniRule annotation1

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionGlycosidaseUniRule annotation, Hydrolase

Protein family/group databases

CAZyiGH20 Glycoside Hydrolase Family 20

Names & Taxonomyi

Protein namesi
Recommended name:
Beta-hexosaminidaseUniRule annotation (EC:3.2.1.52UniRule annotation)
Gene namesi
Name:BmGlcNAcase1Imported
OrganismiBombyx mori (Silk moth)Imported
Taxonomic identifieri7091 [NCBI]
Taxonomic lineageiEukaryotaMetazoaEcdysozoaArthropodaHexapodaInsectaPterygotaNeopteraHolometabolaLepidopteraGlossataDitrysiaBombycoideaBombycidaeBombycinaeBombyx

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Signal peptidei1 – 20Sequence analysisAdd BLAST20
ChainiPRO_500267167821 – 611Beta-hexosaminidaseSequence analysisAdd BLAST591

Proteomic databases

PRIDEiA4PHN6

Structurei

3D structure databases

ProteinModelPortaliA4PHN6
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini143 – 200Glycohydro_20b2InterPro annotationAdd BLAST58
Domaini230 – 569Glyco_hydro_20InterPro annotationAdd BLAST340

Sequence similaritiesi

Belongs to the glycosyl hydrolase 20 family.UniRule annotation

Keywords - Domaini

SignalSequence analysis

Phylogenomic databases

eggNOGiKOG2499 Eukaryota
COG3525 LUCA
KOiK12373

Family and domain databases

Gene3Di3.30.379.10, 1 hit
InterProiView protein in InterPro
IPR025705 Beta_hexosaminidase_sua/sub
IPR015883 Glyco_hydro_20_cat
IPR017853 Glycoside_hydrolase_SF
IPR029018 Hex-like_dom2
IPR029019 HEX_eukaryotic_N
PfamiView protein in Pfam
PF00728 Glyco_hydro_20, 1 hit
PF14845 Glycohydro_20b2, 1 hit
PIRSFiPIRSF001093 B-hxosamndse_ab_euk_, 1 hit
PRINTSiPR00738 GLHYDRLASE20
SUPFAMiSSF51445 SSF51445, 1 hit
SSF55545 SSF55545, 1 hit

Sequencei

Sequence statusi: Complete.

A4PHN6-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MALHRLLALM TTMHLAGVLC NVESTFDEIT PQIYEPSWMY KCVPDEGCQR
60 70 80 90 100
SEHPRPTLSD NSTSAFFDSL DVCRIVCGRF GGIWPKPVTA ALSSQTVKIH
110 120 130 140 150
PNYLRYDLLN VPAETRELLV EMTQVISNNL LAECGGHVTE VVDTQVVVII
160 170 180 190 200
VVKTAITSLN WNTDEQYMLD VQTRGGEVSV HIEAETIYGA RHGLETFSQL
210 220 230 240 250
ISSDKRDFSD VEHCGLVLVS GAKIRDRPIY KHRGLVLDTS RHFIPMVDIK
260 270 280 290 300
RTIDGMATTK MNVFHWHATD SHSFPLEASR VPQFTRYGAY SGSEMYTTEE
310 320 330 340 350
IRELIHYAKV RGIRVVIEID APAHSGNGWQ WGREYGLGDL AVCVNAYPWR
360 370 380 390 400
HLCIEPPCGQ LNPANPNMYR VLRNLYQDVA DLLNSPPLLH MGGDEVYFGC
410 420 430 440 450
WNSSQEIISY MKDQGYDTTE EGFMKLWGEF HNKALQIWDE EISAKGLDPQ
460 470 480 490 500
PVMLWSSQLT QAQRISQHLD KERYIIEVWE PLNSPLLTQL LRLGYRTVSV
510 520 530 540 550
PKDIWYLDHG FWGRTVYSNW RRMYAHTLPR DEGVLGGEVA MWTEYCDAQA
560 570 580 590 600
LDTRVWPRAA AVAERLWSDP TSTVYSAEPR LQRLRTRLIA RGLRPDAMSP
610
AWCSQHDSKC L
Length:611
Mass (Da):69,655
Last modified:May 15, 2007 - v1
Checksum:i18B8D87A7E1F4206
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AB286957 mRNA Translation: BAF52531.1
RefSeqiNP_001078833.1, NM_001085364.1
UniGeneiBmo.3967

Genome annotation databases

GeneIDi100038345
KEGGibmor:100038345

Similar proteinsi

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AB286957 mRNA Translation: BAF52531.1
RefSeqiNP_001078833.1, NM_001085364.1
UniGeneiBmo.3967

3D structure databases

ProteinModelPortaliA4PHN6
ModBaseiSearch...
MobiDBiSearch...

Protein family/group databases

CAZyiGH20 Glycoside Hydrolase Family 20

Proteomic databases

PRIDEiA4PHN6

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

GeneIDi100038345
KEGGibmor:100038345

Organism-specific databases

CTDi100038345

Phylogenomic databases

eggNOGiKOG2499 Eukaryota
COG3525 LUCA
KOiK12373

Family and domain databases

Gene3Di3.30.379.10, 1 hit
InterProiView protein in InterPro
IPR025705 Beta_hexosaminidase_sua/sub
IPR015883 Glyco_hydro_20_cat
IPR017853 Glycoside_hydrolase_SF
IPR029018 Hex-like_dom2
IPR029019 HEX_eukaryotic_N
PfamiView protein in Pfam
PF00728 Glyco_hydro_20, 1 hit
PF14845 Glycohydro_20b2, 1 hit
PIRSFiPIRSF001093 B-hxosamndse_ab_euk_, 1 hit
PRINTSiPR00738 GLHYDRLASE20
SUPFAMiSSF51445 SSF51445, 1 hit
SSF55545 SSF55545, 1 hit
ProtoNetiSearch...

Entry informationi

Entry nameiA4PHN6_BOMMO
AccessioniPrimary (citable) accession number: A4PHN6
Entry historyiIntegrated into UniProtKB/TrEMBL: May 15, 2007
Last sequence update: May 15, 2007
Last modified: May 23, 2018
This is version 58 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health

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