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Protein

Zinc transporter ZIP3

Gene

slc39a3

Organism
Xenopus tropicalis (Western clawed frog) (Silurana tropicalis)
Status
Reviewed-Annotation score: -Experimental evidence at transcript leveli

Functioni

Acts as a zinc-influx transporter.Curated

GO - Molecular functioni

GO - Biological processi

Keywordsi

Biological processIon transport, Transport, Zinc transport
LigandZinc

Names & Taxonomyi

Protein namesi
Recommended name:
Zinc transporter ZIP3
Alternative name(s):
Solute carrier family 39 member 3
Zrt- and Irt-like protein 3
Short name:
ZIP-3
Gene namesi
Name:slc39a3
Synonyms:zip3
OrganismiXenopus tropicalis (Western clawed frog) (Silurana tropicalis)
Taxonomic identifieri8364 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiAmphibiaBatrachiaAnuraPipoideaPipidaeXenopodinaeXenopusSilurana
Proteomesi
  • UP000008143 Componenti: Unassembled WGS sequence

Organism-specific databases

XenbaseiXB-GENE-969593 slc39a3

Subcellular locationi

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Topological domaini1 – 3ExtracellularSequence analysis3
Transmembranei4 – 24HelicalSequence analysisAdd BLAST21
Topological domaini25 – 41CytoplasmicSequence analysisAdd BLAST17
Transmembranei42 – 62HelicalSequence analysisAdd BLAST21
Topological domaini63 – 84ExtracellularSequence analysisAdd BLAST22
Transmembranei85 – 105HelicalSequence analysisAdd BLAST21
Topological domaini106 – 169CytoplasmicSequence analysisAdd BLAST64
Transmembranei170 – 190HelicalSequence analysisAdd BLAST21
Topological domaini191 – 196ExtracellularSequence analysis6
Transmembranei197 – 217HelicalSequence analysisAdd BLAST21
Topological domaini218 – 229CytoplasmicSequence analysisAdd BLAST12
Transmembranei230 – 250HelicalSequence analysisAdd BLAST21
Topological domaini251 – 262ExtracellularSequence analysisAdd BLAST12
Transmembranei263 – 283HelicalSequence analysisAdd BLAST21
Topological domaini284 – 292CytoplasmicSequence analysis9
Transmembranei293 – 313HelicalSequence analysisAdd BLAST21
Topological domaini314ExtracellularSequence analysis1

Keywords - Cellular componenti

Membrane

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00003128711 – 314Zinc transporter ZIP3Add BLAST314

Proteomic databases

PaxDbiA4IIC5
PRIDEiA4IIC5

Interactioni

Protein-protein interaction databases

STRINGi8364.ENSXETP00000008023

Family & Domainsi

Compositional bias

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Compositional biasi163 – 166Poly-Ser4

Sequence similaritiesi

Keywords - Domaini

Transmembrane, Transmembrane helix

Phylogenomic databases

eggNOGiKOG1558 Eukaryota
ENOG4111GP2 LUCA
HOGENOMiHOG000236331
HOVERGENiHBG108447
InParanoidiA4IIC5
KOiK14709

Family and domain databases

InterProiView protein in InterPro
IPR003689 ZIP
PfamiView protein in Pfam
PF02535 Zip, 1 hit

Sequencei

Sequence statusi: Complete.

A4IIC5-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MNLIFAKVLC LLAILVLMML GSLIPVKISE ADFDKSSRSR KILSLSNSFA
60 70 80 90 100
GGVFLATCFN ALLPAVREKF FDLLKIGNIS TDYPLAETIM MVGFFLTVFV
110 120 130 140 150
EQTVMTFRKE KPSFIDMETF NAGSDIGSDS EFESPFISAN HGHNLYEGGH
160 170 180 190 200
SHHSHSLNIK ELSSSSPIRL FSLVFALSAH SVFEGLALGL QEDGNKLLSL
210 220 230 240 250
FIGVVIHETL VAMALGVSMA KVNTHLKDAI KMAVLVSTMI PIGIVVGMAI
260 270 280 290 300
QSAQNMASSI ASALLQGIAG GTFIFVTFFE ILVKELEEKN DRLLKVLFLV
310
LGYTVLAVLV LFKW
Length:314
Mass (Da):34,231
Last modified:May 1, 2007 - v1
Checksum:iA09A62C7774B5B4C
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BC135963 mRNA Translation: AAI35964.1
RefSeqiNP_001096167.1, NM_001102697.1
UniGeneiStr.87049

Genome annotation databases

GeneIDi100124712
KEGGixtr:100124712

Similar proteinsi

Entry informationi

Entry nameiS39A3_XENTR
AccessioniPrimary (citable) accession number: A4IIC5
Entry historyiIntegrated into UniProtKB/Swiss-Prot: December 4, 2007
Last sequence update: May 1, 2007
Last modified: May 23, 2018
This is version 45 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families

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