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Protein

Gremlin

Gene

grem1

Organism
Xenopus tropicalis (Western clawed frog) (Silurana tropicalis)
Status
Unreviewed-Annotation score: -Experimental evidence at transcript leveli

Functioni

GO - Molecular functioni

Keywordsi

Molecular functionCytokineUniRule annotation

Names & Taxonomyi

Protein namesi
Recommended name:
GremlinUniRule annotation
Gene namesi
Name:grem1Imported
OrganismiXenopus tropicalis (Western clawed frog) (Silurana tropicalis)Imported
Taxonomic identifieri8364 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiAmphibiaBatrachiaAnuraPipoideaPipidaeXenopodinaeXenopusSilurana
Proteomesi
  • UP000008143 Componenti: Unassembled WGS sequence

Organism-specific databases

XenbaseiXB-GENE-484543 grem1

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Keywords - Cellular componenti

SecretedUniRule annotation

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Signal peptidei1 – 24UniRule annotationAdd BLAST24
ChainiPRO_501521891725 – 182GremlinUniRule annotationAdd BLAST158

Expressioni

Gene expression databases

BgeeiENSXETG00000018095

Interactioni

GO - Molecular functioni

Protein-protein interaction databases

STRINGi8364.ENSXETP00000039248

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini94 – 181CTCKInterPro annotationAdd BLAST88

Sequence similaritiesi

Belongs to the DAN family.UniRule annotation

Keywords - Domaini

SignalUniRule annotation

Phylogenomic databases

eggNOGiENOG410IG3Z Eukaryota
ENOG4111HEF LUCA
GeneTreeiENSGT00510000046909
HOGENOMiHOG000237358
HOVERGENiHBG051837
OMAiYIPRRAT
OrthoDBiEOG091G0GL9
TreeFamiTF106445

Family and domain databases

Gene3Di2.10.90.10, 1 hit
InterProiView protein in InterPro
IPR006207 Cys_knot_C
IPR029034 Cystine-knot_cytokine
IPR004133 DAN
IPR017159 Gremlin-1/2
PfamiView protein in Pfam
PF03045 DAN, 1 hit
PIRSFiPIRSF037254 Gremlin_precursor, 1 hit
SMARTiView protein in SMART
SM00041 CT, 1 hit

Sequencei

Sequence statusi: Complete.

A4IHD6-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MNCLVYALGS LFLLSGLLLP SSEGKKKVSG SQGAIPPPDK GQPNDSEQGQ
60 70 80 90 100
TQPGGRGRVK GKGQALAAEE VLESSQEALH ITERKYLKRD WCKTQPLKQT
110 120 130 140 150
IHEDGCNSRT IINRFCYGQC NSFYIPRHIR REEGSFQSCS FCKPKKFTTM
160 170 180
VVTLNCPELQ PPTKKKRITR VKQCRCISID LD
Length:182
Mass (Da):20,360
Last modified:May 1, 2007 - v1
Checksum:i19594D791DB60C5D
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AAMC01016523 Genomic DNA No translation available.
AAMC01016524 Genomic DNA No translation available.
BC135479 mRNA Translation: AAI35480.1
RefSeqiNP_001093701.1, NM_001100231.1
UniGeneiStr.31102

Genome annotation databases

EnsembliENSXETT00000039248; ENSXETP00000039248; ENSXETG00000018095
GeneIDi100101711
KEGGixtr:100101711

Similar proteinsi

Entry informationi

Entry nameiA4IHD6_XENTR
AccessioniPrimary (citable) accession number: A4IHD6
Entry historyiIntegrated into UniProtKB/TrEMBL: May 1, 2007
Last sequence update: May 1, 2007
Last modified: July 18, 2018
This is version 83 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported

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