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Entry version 70 (17 Jun 2020)
Sequence version 1 (01 May 2007)
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Protein
Submitted name:

Putative calpain-like cysteine peptidase

Gene

LINJ_27_0500

Organism
Leishmania infantum
Status
Unreviewed-Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Protein inferred from homologyi <p>This indicates the type of evidence that supports the existence of the protein. Note that the 'protein existence' evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywordsi

Molecular functionHydrolaseImported

Protein family/group databases

MEROPS protease database

More...
MEROPSi
C02.A05

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Submitted name:
Putative calpain-like cysteine peptidaseImported (EC:3.4.22.-Imported)
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: 'Name', 'Synonyms', 'Ordered locus names' and 'ORF names'.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
ORF Names:LINJ_27_0500Imported
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiLeishmania infantumImported
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the 'taxonomic identifier' or 'taxid'.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri5671 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryotaDiscobaEuglenozoaKinetoplasteaMetakinetoplastinaTrypanosomatidaTrypanosomatidaeLeishmaniinaeLeishmania
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000008153 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes%5Fmanual">proteome</a> can consist of several components.<br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome 27

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/family%5Fand%5Fdomains%5Fsection">Family and Domains</a> section describes the position and type of a domain, which is defined as a specific combination of secondary structures organized into a characteristic three-dimensional structure or fold.<p><a href='/help/domain' target='_top'>More...</a></p>Domaini32 – 304Calpain catalyticInterPro annotationAdd BLAST273
Domaini626 – 920Calpain catalyticInterPro annotationAdd BLAST295
Domaini5369 – 5645Calpain catalyticInterPro annotationAdd BLAST277

Region

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Family and Domains' section describes a region of interest that cannot be described in other subsections.<p><a href='/help/region' target='_top'>More...</a></p>Regioni1220 – 1254DisorderedSequence analysisAdd BLAST35
Regioni5184 – 5212DisorderedSequence analysisAdd BLAST29
Regioni5291 – 5363DisorderedSequence analysisAdd BLAST73
Regioni5925 – 5982DisorderedSequence analysisAdd BLAST58

Coiled coil

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Family and domains' section denotes the positions of regions of coiled coil within the protein.<p><a href='/help/coiled' target='_top'>More...</a></p>Coiled coili1286 – 1313Sequence analysisAdd BLAST28
Coiled coili1371 – 1391Sequence analysisAdd BLAST21
Coiled coili1570 – 1590Sequence analysisAdd BLAST21
Coiled coili1776 – 1796Sequence analysisAdd BLAST21

Compositional bias

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Family and Domains' section describes the position of regions of compositional bias within the protein and the particular amino acids that are over-represented within those regions.<p><a href='/help/compbias' target='_top'>More...</a></p>Compositional biasi1224 – 1239PolarSequence analysisAdd BLAST16
Compositional biasi5192 – 5212PolyampholyteSequence analysisAdd BLAST21
Compositional biasi5291 – 5312PolyampholyteSequence analysisAdd BLAST22
Compositional biasi5323 – 5350PolyampholyteSequence analysisAdd BLAST28
Compositional biasi5925 – 5965PolarSequence analysisAdd BLAST41

<p>This subsection of the 'Family and domains' section provides information about the sequence similarity with other proteins.<p><a href='/help/sequence_similarities' target='_top'>More...</a></p>Sequence similaritiesi

Belongs to the peptidase C2 family.SAAS annotation

Keywords - Domaini

Coiled coilSequence analysis

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

More...
eggNOGi
KOG0045 Eukaryota
ENOG410XP0B LUCA

InParanoid: Eukaryotic Ortholog Groups

More...
InParanoidi
A4I2N5

Identification of Orthologs from Complete Genome Data

More...
OMAi
HDLACDK

Family and domain databases

Integrated resource of protein families, domains and functional sites

More...
InterProi
View protein in InterPro
IPR022684 Calpain_cysteine_protease
IPR022682 Calpain_domain_III
IPR036213 Calpain_III_sf
IPR038765 Papain-like_cys_pep_sf
IPR001300 Peptidase_C2_calpain_cat

Pfam protein domain database

More...
Pfami
View protein in Pfam
PF01067 Calpain_III, 2 hits
PF00648 Peptidase_C2, 3 hits

Protein Motif fingerprint database; a protein domain database

More...
PRINTSi
PR00704 CALPAIN

Simple Modular Architecture Research Tool; a protein domain database

More...
SMARTi
View protein in SMART
SM00230 CysPc, 1 hit

Superfamily database of structural and functional annotation

More...
SUPFAMi
SSF49758 SSF49758, 3 hits
SSF54001 SSF54001, 3 hits

PROSITE; a protein domain and family database

More...
PROSITEi
View protein in PROSITE
PS50203 CALPAIN_CAT, 3 hits

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence%5Flength">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequencei

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences%5Fsection">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

A4I2N5-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MAASSIHETP DSGEVFADHE FNKNNAGITD DWISIRQLYP AGVNQPLLPE
60 70 80 90 100
VFSREQFGQG NHYECFMLSA LATLIRFPDV IRNCFVTKKV RQDGRYTFQF
110 120 130 140 150
FRGQEWVKVE IDDRIAMEEG EVLYARSPTE HWWPLLLEKA YAKFYTAYDH
160 170 180 190 200
LEGCTLLETF HDLTGNPVLN IPMDAKLAKA ANCNVLEGRY WLDLAQRIQS
210 220 230 240 250
GEFVASALTK DVEVETMGLQ REQQYGILDI FSLHGTSSLD DILVHMHNPF
260 270 280 290 300
EDDEFLYSGP LNPNDSAWSE KQRVKYDVGN PRSIFLPLNV FLRIVNSMQL
310 320 330 340 350
CYISTVASDA TYFEDEWKGE SAGGNPTYVT WRKNPLYYIS NHGTEAVTLS
360 370 380 390 400
FVVKQEDQRH RKGPEETATY KQCGMILSQY SYLYPIPTFW VTGNNHKPIH
410 420 430 440 450
KSLFLNSREV ASSVIVPPQS LCYLVPSCMH QGEEARFLLS AHRMVHEDYS
460 470 480 490 500
NITIKKLTVP EMDWENPAAG TVQLQMRTKD RLDFYVDEPT DVHILLHQTK
510 520 530 540 550
PYVSPKTGGD AMAQDYMGMY LYDDTDRKIA GVHAATNFRE TSIIHRLPRS
560 570 580 590 600
GRYAISITCP RGKGHITANV TIVSSFGSHI RRVNAPEDAA MLPDEAESVA
610 620 630 640 650
DSEGVDTRVA RIDYNPFQEQ PVDVREHPDS NVPFEDRGFM LSNRDVTSEP
660 670 680 690 700
WLHIGDLYPE GKTRPLLPNV LSRDQFGQGA MHECCCLTGF ATLIENHPDV
710 720 730 740 750
IRNCFISKNP RKDGRYTFQF HRYGQWIKVE IDDRIPMVKG DTVFCRSPTH
760 770 780 790 800
HWWPLLLEKA YAKFYTLYEN LAGCSLAEVY HDFSGCPVIN TPLDEVTAKS
810 820 830 840 850
VGFDIASPVY WVRLRDELRM TAVAALSGDN AESLGLAPHQ FYGILNILAT
860 870 880 890 900
SSPPRTLSEV IVQLHNPYAE ISYTGPMSDP ADPRWASREM RHCNATQNTI
910 920 930 940 950
FVPVNVFLRS FFTISQAHLR GLMEPCWNFH SEWGDGTNGG NPSLLTWREN
960 970 980 990 1000
PLYIVRNTGS EAVEVMGMIR QPDKRHQLHV LPELSYVRCD LLLAQSIETD
1010 1020 1030 1040 1050
SIPTYLVTHN NHDVVHKRVF LNYREVASKI RVPPQSQCYL VPTAMYHEKS
1060 1070 1080 1090 1100
IFLLSYWYRT PADEGAVSIE RLRVNVARDL PAVKHVTLVP EGKDRVDFFV
1110 1120 1130 1140 1150
DVPTDAHILL SQWNRDARGG SNVRTDNYVG MYLYDDANQK MAQVSAASNL
1160 1170 1180 1190 1200
KEIGLVAHLP AQGHYVLSIT CPAARDEEVK CRVEIVCVEM ARVRITDVYE
1210 1220 1230 1240 1250
NPPSSEELEG EPPVALVDSD TARSDVGDGT QSVEATVETR PPANTEAKER
1260 1270 1280 1290 1300
EKTPSLSFMR PRYQGIWTED LLLMETPAFA KMAGEREQLK KHASQHAARM
1310 1320 1330 1340 1350
NSLENKMEDM ATRLADDMHD QERAFLGPEL EGVPLELLPL NEDEEFTGLE
1360 1370 1380 1390 1400
HELRVAMRDL QKNRGDVVAL RETLKERAGE MAKKLKENER DLFLNPMPLG
1410 1420 1430 1440 1450
ISCDGLPLDS DPEFHALEVA RLRERQEESC DEAKIRKLND ALNERAEGLA
1460 1470 1480 1490 1500
RAKLAADRQY LKPEHLRVAV DELPLNDDRN FILKEALRHE KLKNSRESAA
1510 1520 1530 1540 1550
AIAALGNELN NMAKGMAAEM LAKQRPSYLA REHHGRRMED LLLNDNDDFL
1560 1570 1580 1590 1600
KKERRRRDLL KQPSSDMDVV AEIEKELNGM ADEMARAMNA AERPQYMKAS
1610 1620 1630 1640 1650
YYDKTLSELP LDTDPIIARL EAQRARLKRD PVRNAEAVHA TEAAIISRAE
1660 1670 1680 1690 1700
ALAKAMIKDE RARLYGKPSG VPVNLLDLDE DQVIRRLEEE RMELLKMPNT
1710 1720 1730 1740 1750
DPHAIASNEE KLKARAAKIA EDFRDNMRAQ ITGEGRRSPS VMSIGSDAPC
1760 1770 1780 1790 1800
QDLEEKLYAL MSEDPIANED QINDIKDAIR KRNAELKRQA VQALRAFLDD
1810 1820 1830 1840 1850
KPFGILLTEV GLDDDREYME REEKLKKGQA SNLPAAQITF IQEGMQHRVN
1860 1870 1880 1890 1900
ELAAEELARR YPFIHTRPAS IPLPALPSVG RDQAFWKAID NVDKAKNHHN
1910 1920 1930 1940 1950
TATSQLRAYE KSVNERLHQI AEAAKWKERD GFLDSRPAHV PVKAIPLDND
1960 1970 1980 1990 2000
TDFVDLESKR RLSLQSGADP QSDDIRTLEK ALRTRAHDLA CDKKWADRDR
2010 2020 2030 2040 2050
VLDPKPEGVP LRCVPLDEDA EFVALEDEWR GLLQDPQRNS MPLKDLERRM
2060 2070 2080 2090 2100
NDRAHDLACD KKWADRDRVL DPKPEGVPLR CVPLDEDAEF VALEDEWRGL
2110 2120 2130 2140 2150
LQDPQRNSMP LKDLERRMND RAHDLACDKK WADRDRVLDP KPEGVPLRCV
2160 2170 2180 2190 2200
PLDEDAEFVA LEDEWRGLLQ DPQRNSMPLK DLERRMNDRA HDLACDKKWA
2210 2220 2230 2240 2250
DRDRVLDPKP EGVPLRCVPL DEDAEFVALE DEWRGLLQDP QRNSMPLKDL
2260 2270 2280 2290 2300
ERRMNDRAHD LACDKKWAGR DRVLDPKPEG VPLRCVPLDE DAEFVALEDE
2310 2320 2330 2340 2350
WRGLLQDPQR SSMPLKDLER RMNDRAHDLA CDKKWADRDR VLDPKPEGVP
2360 2370 2380 2390 2400
LRCVPLDEDA EFLALEDEWR GLLQDPQRNS MPLKDLERRM NDRAHDLACD
2410 2420 2430 2440 2450
KKWADRDRVL DPKPEGVPLR CVPLDEDAEF LALEDEWRGL LQDPQRNSMP
2460 2470 2480 2490 2500
LKDLERRMND RAHDLACDKK WADRDRVLDP KPEGVPLRCV PLDEDAEFLA
2510 2520 2530 2540 2550
LEDEWRGLLQ DPQRNSMPLK DLERRMNDRA HDLACDKKWA GRDRVLDPKP
2560 2570 2580 2590 2600
EGVPLRCVPL DEDAEFVALE DEWRGLLQDP QRSSMPLKDL ERRMNDRAHD
2610 2620 2630 2640 2650
LACDKKWADR DRVLDPKPEG VPLRCVPLDE DAEFVALEDE WRGLLQDPQR
2660 2670 2680 2690 2700
NSMLLKDLER RMNDRAHDLA CDKKWAGRDR VLDPKPEGVP LRCVPLDEDA
2710 2720 2730 2740 2750
EFVALEDEWR GLLQDPQRSS MPLKDLERRM NDRAHDLACD KKWADRDRVL
2760 2770 2780 2790 2800
DPKPEGVPLR CVPLDEDAEF LALEDEWRGL LQDPQRNSMP LKDLERRMND
2810 2820 2830 2840 2850
RAHDLACDKK WADRDRVLDP KPEGVPLRCV PLDEDAEFLA LEDEWRGLLQ
2860 2870 2880 2890 2900
DPQRNSMPLK DLERRMNDRA HDLACDKKWA GRDRVLDPKP EGVPLRCVPL
2910 2920 2930 2940 2950
DEDAEFVALE DEWRGLLQDP QRSSMPLKDL ERRMNDRAHD LACDKKWAGR
2960 2970 2980 2990 3000
DRVLDPKPEG VPLRCVPLDE DAEFVALEDE WRGLLQDPQR SSMPLKDLER
3010 3020 3030 3040 3050
RMNDRAHDLA CDKKWAGRDR VLDPKPEGVP LRCVPLDEDA EFLALEDEWR
3060 3070 3080 3090 3100
GLLQDPQRNS MPLKDLERRM NDRAHDLACD KKWAGRDRVL DPKPEGVPLR
3110 3120 3130 3140 3150
CVPLDEDAEF VALEDEWRGL LQDPQRNSMP LKDLERRMND RAHDLACDKK
3160 3170 3180 3190 3200
WADRDRVLDP KPEGVPLRCV PLDEDAEFVA LEDEWRGLLQ DPQRSSMPLK
3210 3220 3230 3240 3250
DLERRMNDRA HDLACDKKWA DRDRVLDPKP EGVPLRCVPL DEDAEFVALE
3260 3270 3280 3290 3300
DEWRGLLQDP QRNSMPLKDL ERRMNDRAHD LACDKKWADR DRVLDPKPEG
3310 3320 3330 3340 3350
VPLRCVPLDE DAEFVALEDE WRGLLQDPQR NSMPLKDLER RMNDRAHDLA
3360 3370 3380 3390 3400
CDKKWADRDR VLDPKPEGVP LRCVPLDEDA EFVALEDEWR GLLQDPQRSS
3410 3420 3430 3440 3450
MPLKDLERRM NDRAHDLACD KKWADRDRVL DPKPEGVPLR CVPLDEDAEF
3460 3470 3480 3490 3500
VALEDEWRGL LQDPQRNSMP LKDLERRMND RAHDLACDKK WADRDRVLDP
3510 3520 3530 3540 3550
KPEGVPLRCV PLDEDAEFVA LEDEWRGLLQ DPQRNSMPLK DLERRMNDRA
3560 3570 3580 3590 3600
HDLACDKKWA DRDRVLDPKP EGVPLRCVPL DEDAEFLALE DEWRGLLQDP
3610 3620 3630 3640 3650
QRNSMPLKDL ERRMNDRAHD LACDKKWADR DRVLDPKPEG VPLRCVPLDE
3660 3670 3680 3690 3700
DAEFLALEDE WRGLLQDPQR NSMPLKDLER RMNDRAHDLA CDKKWADRDR
3710 3720 3730 3740 3750
VLDPKPEGVP LRCVPLDEDA EFLALEDEWR GLLQDPQRNS MPLKDLERRM
3760 3770 3780 3790 3800
NDRAHDLACD KKWADRDRVL DPKPEGVPLR CVPLDEDAEF LALEDEWRGL
3810 3820 3830 3840 3850
LQDPQRNSMP LKDLERRMND RAHDLACDKK WAGRDRVLDP KPEGVPLRCV
3860 3870 3880 3890 3900
PLDEDAEFVA LEDEWRGLLQ DPQRSSMPLK DLERRMNDRA HDLACDKKWA
3910 3920 3930 3940 3950
GRDRVLDPKP EGVPLRCVPL DEDAEFVALE DEWRGLLQDP QRSSMPLKDL
3960 3970 3980 3990 4000
ERRMNDRAHD LACDKKWADR DRVLDPKPEG VPLRCVPLDE DAEFVALEDE
4010 4020 4030 4040 4050
WRGLLQDPQR SSMPLKDLER RMNDRAHDLA CDKKWADRDR VLDPKPEGVP
4060 4070 4080 4090 4100
LRCVPLDEDA EFVALEDEWR GLLQDPQRNS MPLKDLERRM NDRAHDLACD
4110 4120 4130 4140 4150
KKWADRDRVL DPKPEGVPLR CVPLDEDAEF VALEDEWRGL LQDPQRSSMP
4160 4170 4180 4190 4200
LKDLERRMND RAHDLACDKK WAGRDRVLDP KPEGVPLRCV PLDEDAEFLA
4210 4220 4230 4240 4250
LEDEWRGLLQ DPQRSSMPLK DLERRMNDRA HDLACDKKWA DRDRVLDPKP
4260 4270 4280 4290 4300
EGVPLRCVPL DEDAEFVALE DEWRGLLQDP QRNSMPLKDL ERRMNDRAHD
4310 4320 4330 4340 4350
LACDKKWADR DRVLDPKPEG VPLRCVPLDE DAEFVALEDE WRGLLQDPQR
4360 4370 4380 4390 4400
SSMPLKDLER RMNDRAHDLA CDKKWADRDR VLDPKPEGVP LRCVPLDEDA
4410 4420 4430 4440 4450
EFVALEDEWR GLLQDPQRNS MPLKDLERRM NDRAHDLACD KKWADRDRVL
4460 4470 4480 4490 4500
DPKPEGVPLR CVPLDEDAEF LALEDEWRGL LQDPQRSSMP LKDLERRMND
4510 4520 4530 4540 4550
RAHDLACDKK WADRDRVLDP KPEGVPLRCV PLDEDAEFVA LEDEWRGLLQ
4560 4570 4580 4590 4600
DPQRSSMPLK DLERRMNDRA HDVACGKKWA DRDRVLDPKP EGVPLRCVPL
4610 4620 4630 4640 4650
DEDAEFVALE DEWRGLLQDP QRSSMPLKDL ERRMNDRAHD LACDKKWADR
4660 4670 4680 4690 4700
DRVLDPKPEG VPLRCVPLDE DAEFVALEDE WRGLLQDPQR SSMPLKDLER
4710 4720 4730 4740 4750
RMNDRAHDLA CDKKWADRDR VLDPKPEGVP LRCVPLDEDA EFVALEDEWR
4760 4770 4780 4790 4800
GLLQDPQRSS MPLKDLERRM NDRAHDLACD KKWAGRDRVL DPKPEGVPLR
4810 4820 4830 4840 4850
CVPLDEDAEF VALEDEWRGL LQDPQRSSMP LKDLERRMND RAHDVACGKK
4860 4870 4880 4890 4900
WADRDRVLDP KPEGVPLRCV PLDEDAEFVA LEDEWRGLLQ DPQRNSMPLK
4910 4920 4930 4940 4950
DLERRMNDRA HDLACGKKWA DRDRVLDPKP EGVPLHCVPL DEDAEFVALE
4960 4970 4980 4990 5000
DEWRGLLQDP QRNAKRIAVL EEDMTARALL VGQIVNRRNE DGDVEEYEDY
5010 5020 5030 5040 5050
VKRGASEFCD VDDRNTDDAT VAMSVGNGRL SMKEGFKELL GTEVDGVPVL
5060 5070 5080 5090 5100
LLNLDEDSLF SERNREYMNS EKLGLDRSRI CWLEEKMIDR AYALARRFKD
5110 5120 5130 5140 5150
EARKVIVGVQ MSQMAEGGAE LDSDEIFLAF ERELHNLEAC DPRGKSGRRA
5160 5170 5180 5190 5200
ALEESMRHRA SELARPVLHF DNGGIPVDML NEQSNGELFP KRPDGGRQRR
5210 5220 5230 5240 5250
SSKDIGHREL GTNKRRCHIA DEAVADDPSL LFGREIRGVP VDRIPLREDE
5260 5270 5280 5290 5300
VFRGLAEEKR RVTSHPEDYS SGYKEEVEDA MRRRVEELAD EYKRDHVERT
5310 5320 5330 5340 5350
AARDERPKMP AKPNGVSKES GGAARRPRAK KKLKEVEERT EEHRLETVEE
5360 5370 5380 5390 5400
AAPFTDPPFH SANKQVADSW PRIADVYPEG LTQPLLPDHP KASDMASSAG
5410 5420 5430 5440 5450
DLTYLAPFLA ALSRQPPLLH RLFQTKMHPV RAPYRFVFFD PNSAPVTVEI
5460 5470 5480 5490 5500
DDRIPCDVNG VPRFTVSPSG AWWPLLVERA YAKYVGGYER FDQCTSHETL
5510 5520 5530 5540 5550
RDLTGRPVTH LPLDAKLSAE VVGCNYRDVA FWRRIHEQLE RGDVFVAVSG
5560 5570 5580 5590 5600
DLVPDGIHPR CYYAVFDVIE TVPGSNDPSD VVVKIHNCYH DAPQYHGPLA
5610 5620 5630 5640 5650
MGDSDWTPIL RSVCKANPES EPEFLYLPQP VFLRNFSSMQ RCHINCGDRL
5660 5670 5680 5690 5700
TVSGEWADNC SGGSPTYTTF RQNPMYLLQN NSNHNVTVLA ELRHSAPVYY
5710 5720 5730 5740 5750
DAHNMGVYHL TALALLRPDR NAQLVAPLLA HNTHKFVQKG LLTDAREVCA
5760 5770 5780 5790 5800
EMELPANSTC YLIPYTKKKA CFGKYQLSVY PQDNPVNLTT LRPIAETHNC
5810 5820 5830 5840 5850
MAKDVVVQPG SGTSARVDIM VSEPCDVHAL LHQNKVTDPT AMRRGDHLAE
5860 5870 5880 5890 5900
DEIFMAAYEN NALLVCSTGD ASNAREHSVA FQAAKAGRYT FLIGCPSRPV
5910 5920 5930 5940 5950
SGDAPCTLII YTPKFAQASF ASVNGSTRSR VPPRVQPVNA ATTSASARLG
5960 5970 5980
SWQSQAPQSY APVSNGAVHT PRGNPRSREY LQ
Length:5,982
Mass (Da):686,970
Last modified:May 1, 2007 - v1
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:iAA71BD3A4087F343
GO

Sequence databases

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EMBL nucleotide sequence database

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EMBLi

GenBank nucleotide sequence database

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GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

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DDBJi
Links Updated
FR796459 Genomic DNA Translation: CAM69030.1

NCBI Reference Sequences

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RefSeqi
XP_001466318.1, XM_001466281.1

Genome annotation databases

GeneDB pathogen genome database from Sanger Institute

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GeneDBi
LinJ.27.0500:pep

Database of genes from NCBI RefSeq genomes

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GeneIDi
5070025

KEGG: Kyoto Encyclopedia of Genes and Genomes

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KEGGi
lif:LINJ_27_0500

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
FR796459 Genomic DNA Translation: CAM69030.1
RefSeqiXP_001466318.1, XM_001466281.1

3D structure databases

Database of comparative protein structure models

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ModBasei
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SWISS-MODEL Interactive Workspace

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SWISS-MODEL-Workspacei
Submit a new modelling project...

Protein family/group databases

MEROPSiC02.A05

Genome annotation databases

GeneDBiLinJ.27.0500:pep
GeneIDi5070025
KEGGilif:LINJ_27_0500

Phylogenomic databases

eggNOGiKOG0045 Eukaryota
ENOG410XP0B LUCA
InParanoidiA4I2N5
OMAiHDLACDK

Family and domain databases

InterProiView protein in InterPro
IPR022684 Calpain_cysteine_protease
IPR022682 Calpain_domain_III
IPR036213 Calpain_III_sf
IPR038765 Papain-like_cys_pep_sf
IPR001300 Peptidase_C2_calpain_cat
PfamiView protein in Pfam
PF01067 Calpain_III, 2 hits
PF00648 Peptidase_C2, 3 hits
PRINTSiPR00704 CALPAIN
SMARTiView protein in SMART
SM00230 CysPc, 1 hit
SUPFAMiSSF49758 SSF49758, 3 hits
SSF54001 SSF54001, 3 hits
PROSITEiView protein in PROSITE
PS50203 CALPAIN_CAT, 3 hits

ProtoNet; Automatic hierarchical classification of proteins

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ProtoNeti
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MobiDB: a database of protein disorder and mobility annotations

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MobiDBi
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<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the 'Entry information' section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiA4I2N5_LEIIN
<p>This subsection of the 'Entry information' section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called 'Primary (citable) accession number'.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: A4I2N5
<p>This subsection of the 'Entry information' section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification ('Last modified'). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/TrEMBL: May 1, 2007
Last sequence update: May 1, 2007
Last modified: June 17, 2020
This is version 70 of the entry and version 1 of the sequence. See complete history.
<p>This subsection of the 'Entry information' section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiUnreviewed (UniProtKB/TrEMBL)

<p>This section contains any relevant information that doesn't fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Reference proteomeImported
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