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UniProtKB - A4HZ02 (A4HZ02_LEIIN)
Protein
RNA ligase (ATP)
Gene
REL2
Organism
Leishmania infantum
Status
Functioni
Catalytic activityi
- ATP + (ribonucleotide)(n)-3'-hydroxyl + 5'-phospho-(ribonucleotide)(m) = (ribonucleotide)(n+m) + AMP + diphosphate.ARBA annotation EC:6.5.1.3
GO - Molecular functioni
- ATP binding Source: UniProtKB-KW
- RNA ligase (ATP) activity Source: UniProtKB-EC
Keywordsi
Molecular function | LigaseImportedARBA annotation |
Ligand | ATP-bindingARBA annotation, Nucleotide-binding |
Names & Taxonomyi
Protein namesi | |
Gene namesi | Name:REL2Imported ORF Names:LINJ_20_1700Imported |
Organismi | Leishmania infantumImported |
Taxonomic identifieri | 5671 [NCBI] |
Taxonomic lineagei | Eukaryota › Discoba › Euglenozoa › Kinetoplastea › Metakinetoplastina › Trypanosomatida › Trypanosomatidae › Leishmaniinae › Leishmania › |
Proteomesi |
|
Organism-specific databases
VEuPathDBi | TriTrypDB:LINF_200021800 |
Family & Domainsi
Phylogenomic databases
eggNOGi | ENOG502RW2V, Eukaryota |
InParanoidi | A4HZ02 |
OMAi | CTAFQEI |
Family and domain databases
Gene3Di | 1.10.10.1810, 1 hit |
InterProi | View protein in InterPro IPR012647, RNA_lig_RNL2 IPR021122, RNA_ligase_dom_REL/Rnl2 IPR041948, Rnl1/2_C_sf IPR040609, Rnl2_C |
Pfami | View protein in Pfam PF09414, RNA_ligase, 1 hit PF18043, T4_Rnl2_C, 1 hit |
TIGRFAMsi | TIGR02307, RNA_lig_RNL2, 1 hit |
i Sequence
Sequence statusi: Complete.
A4HZ02-1 [UniParc]FASTAAdd to basket
10 20 30 40 50
MFRRCLLTRL VRRSLVLFSD EKEALFERYS EIENAHSRRI EALKDAGLFN
60 70 80 90 100
DEWIATEKVH GANFGIYSTE HGKTIQYAKR SGIMPPYEHF FGYHILIPDL
110 120 130 140 150
VRYAKQGREL LTEQLGMSPS TVIINGELFG GKYDHPSVPK RRQNVMVAGR
160 170 180 190 200
PRTITAVQNN AFPQYCPDLH FYAFDIKYRR TEEEEYCTMT YDQALAIFEK
210 220 230 240 250
ISGLLYAKAI IRGPLSKVAA FDVENFVTTI PPLVGMGDYP LKGNWAEGLV
260 270 280 290 300
VKHCRRGEPG FDAKGLTIMK FKCTAFQEIS TDRRQGPRVD ALEEVRRQSI
310 320 330 340 350
KVSGVQLPDM ESVIRDPEVR QATHHLLDHV CENRLQSVLS KIGTGPFETQ
360 370 380 390 400
SMTPTELSTL LAKDALKDFL KEADAKIVNT PLLVRREMAR YVLFEARRYV
410
ASRWKDVVGQ QREADGES
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | FR796452 Genomic DNA Translation: CAM67543.1 |
RefSeqi | XP_001465293.1, XM_001465256.1 |
Genome annotation databases
GeneIDi | 5068711 |
KEGGi | lif:LINJ_20_1700 |
Similar proteinsi
Cross-referencesi
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | FR796452 Genomic DNA Translation: CAM67543.1 |
RefSeqi | XP_001465293.1, XM_001465256.1 |
3D structure databases
AlphaFoldDBi | A4HZ02 |
SMRi | A4HZ02 |
ModBasei | Search... |
Genome annotation databases
GeneIDi | 5068711 |
KEGGi | lif:LINJ_20_1700 |
Organism-specific databases
VEuPathDBi | TriTrypDB:LINF_200021800 |
Phylogenomic databases
eggNOGi | ENOG502RW2V, Eukaryota |
InParanoidi | A4HZ02 |
OMAi | CTAFQEI |
Family and domain databases
Gene3Di | 1.10.10.1810, 1 hit |
InterProi | View protein in InterPro IPR012647, RNA_lig_RNL2 IPR021122, RNA_ligase_dom_REL/Rnl2 IPR041948, Rnl1/2_C_sf IPR040609, Rnl2_C |
Pfami | View protein in Pfam PF09414, RNA_ligase, 1 hit PF18043, T4_Rnl2_C, 1 hit |
TIGRFAMsi | TIGR02307, RNA_lig_RNL2, 1 hit |
MobiDBi | Search... |
Entry informationi
Entry namei | A4HZ02_LEIIN | |
Accessioni | A4HZ02Primary (citable) accession number: A4HZ02 Secondary accession number(s): A0A2K4YT60, A0A381MGZ1 | |
Entry historyi | Integrated into UniProtKB/TrEMBL: | May 1, 2007 |
Last sequence update: | May 1, 2007 | |
Last modified: | May 25, 2022 | |
This is version 73 of the entry and version 1 of the sequence. See complete history. | ||
Entry statusi | Unreviewed (UniProtKB/TrEMBL) |