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Protein

Non-specific serine/threonine protein kinase

Gene

Stk38l

Organism
Rattus norvegicus (Rat)
Status
Unreviewed-Annotation score: -Experimental evidence at protein leveli

Functioni

Catalytic activityi

ATP + a protein = ADP + a phosphoprotein.SAAS annotation

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionKinase, Serine/threonine-protein kinaseUniRule annotationSAAS annotation, Transferase
LigandATP-bindingUniRule annotationSAAS annotation, Nucleotide-binding

Names & Taxonomyi

Protein namesi
Recommended name:
Non-specific serine/threonine protein kinaseSAAS annotation (EC:2.7.11.1SAAS annotation)
Gene namesi
Name:Stk38lImported
ORF Names:rCG_29601Imported
OrganismiRattus norvegicus (Rat)Imported
Taxonomic identifieri10116 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaMyomorphaMuroideaMuridaeMurinaeRattus
Proteomesi
  • UP000002494 Componenti: Chromosome 4

Organism-specific databases

RGDi1564793 Stk38l

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Expressioni

Gene expression databases

BgeeiENSRNOG00000001828 Expressed in 9 organ(s), highest expression level in colon

Interactioni

Protein-protein interaction databases

IntActiA4GW50, 1 interactor
STRINGi10116.ENSRNOP00000002502

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini90 – 383Protein kinaseInterPro annotationAdd BLAST294
Domaini384 – 453AGC-kinase C-terminalInterPro annotationAdd BLAST70

Sequence similaritiesi

Belongs to the protein kinase superfamily.UniRule annotation

Phylogenomic databases

eggNOGiKOG0605 Eukaryota
ENOG410XQC0 LUCA
GeneTreeiENSGT00760000118994
HOVERGENiHBG104247
KOiK08790
OMAiNAIHLTM
TreeFamiTF105337

Family and domain databases

InterProiView protein in InterPro
IPR000961 AGC-kinase_C
IPR011009 Kinase-like_dom_sf
IPR017892 Pkinase_C
IPR000719 Prot_kinase_dom
IPR017441 Protein_kinase_ATP_BS
IPR008271 Ser/Thr_kinase_AS
PfamiView protein in Pfam
PF00069 Pkinase, 1 hit
PF00433 Pkinase_C, 1 hit
SMARTiView protein in SMART
SM00220 S_TKc, 1 hit
SUPFAMiSSF56112 SSF56112, 2 hits
PROSITEiView protein in PROSITE
PS51285 AGC_KINASE_CTER, 1 hit
PS00107 PROTEIN_KINASE_ATP, 1 hit
PS50011 PROTEIN_KINASE_DOM, 1 hit
PS00108 PROTEIN_KINASE_ST, 1 hit

Sequencei

Sequence statusi: Complete.

A4GW50-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MAMTAGATTT FPMSSHTRER VTVAKLTLEN FYSNLILQHE ERETRQKKLE
60 70 80 90 100
VAMEEEGLAD EEKKLRRSQH ARKETEFLRL KRTRLGLDDF ESLKVIGRGA
110 120 130 140 150
FGEVRLVQKK DTGHIYAMKI LRKADMLEKE QVAHIRAERD ILVEADGAWV
160 170 180 190 200
VKMFYSFQDK RNLYLIMEFL PGGDMMTLLM KKDTLTEEET QFYISETVLA
210 220 230 240 250
IDAIHQLGFI HRDIKPDNLL LDAKGHVKLS DFGLCTGLKK AHRTEFYRNL
260 270 280 290 300
THNPPSDFSF QNMNSKRKAE TWKKNRRQLA YSTVGTPDYI APEVFMQTGY
310 320 330 340 350
NKLCDWWSLG VIMYEMLIGF PPFCSETPQE TYRKVMSWKE TLAFPPEVPV
360 370 380 390 400
SEKAKDLILR FCTDSENRIG NGGVEEIKGH PFFEGVDWGH IRERPAAIPI
410 420 430 440 450
EIRSIDDTSN FDDFPESDIL QPVPNTTEPD YKSKDWVFLN YTYKRFEGLT
460
QRGSIPTYMK AGKL
Length:464
Mass (Da):53,759
Last modified:April 17, 2007 - v1
Checksum:iA4441AA40093AF57
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AABR07062516 Genomic DNA No translation available.
AABR07062517 Genomic DNA No translation available.
AABR07062518 Genomic DNA No translation available.
AABR07062519 Genomic DNA No translation available.
AABR07062520 Genomic DNA No translation available.
BC160812 mRNA Translation: AAI60812.1
EF444939 mRNA Translation: ABO26295.1
CH473964 Genomic DNA Translation: EDM01408.1
RefSeqiNP_001076805.1, NM_001083336.1
XP_017448391.1, XM_017592902.1
UniGeneiRn.200326

Genome annotation databases

EnsembliENSRNOT00000002502; ENSRNOP00000002502; ENSRNOG00000001828
ENSRNOT00000086813; ENSRNOP00000068621; ENSRNOG00000001828
GeneIDi691337
KEGGirno:691337
UCSCiRGD:1564793 rat

Similar proteinsi

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AABR07062516 Genomic DNA No translation available.
AABR07062517 Genomic DNA No translation available.
AABR07062518 Genomic DNA No translation available.
AABR07062519 Genomic DNA No translation available.
AABR07062520 Genomic DNA No translation available.
BC160812 mRNA Translation: AAI60812.1
EF444939 mRNA Translation: ABO26295.1
CH473964 Genomic DNA Translation: EDM01408.1
RefSeqiNP_001076805.1, NM_001083336.1
XP_017448391.1, XM_017592902.1
UniGeneiRn.200326

3D structure databases

ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

IntActiA4GW50, 1 interactor
STRINGi10116.ENSRNOP00000002502

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENSRNOT00000002502; ENSRNOP00000002502; ENSRNOG00000001828
ENSRNOT00000086813; ENSRNOP00000068621; ENSRNOG00000001828
GeneIDi691337
KEGGirno:691337
UCSCiRGD:1564793 rat

Organism-specific databases

CTDi23012
RGDi1564793 Stk38l

Phylogenomic databases

eggNOGiKOG0605 Eukaryota
ENOG410XQC0 LUCA
GeneTreeiENSGT00760000118994
HOVERGENiHBG104247
KOiK08790
OMAiNAIHLTM
TreeFamiTF105337

Gene expression databases

BgeeiENSRNOG00000001828 Expressed in 9 organ(s), highest expression level in colon

Family and domain databases

InterProiView protein in InterPro
IPR000961 AGC-kinase_C
IPR011009 Kinase-like_dom_sf
IPR017892 Pkinase_C
IPR000719 Prot_kinase_dom
IPR017441 Protein_kinase_ATP_BS
IPR008271 Ser/Thr_kinase_AS
PfamiView protein in Pfam
PF00069 Pkinase, 1 hit
PF00433 Pkinase_C, 1 hit
SMARTiView protein in SMART
SM00220 S_TKc, 1 hit
SUPFAMiSSF56112 SSF56112, 2 hits
PROSITEiView protein in PROSITE
PS51285 AGC_KINASE_CTER, 1 hit
PS00107 PROTEIN_KINASE_ATP, 1 hit
PS50011 PROTEIN_KINASE_DOM, 1 hit
PS00108 PROTEIN_KINASE_ST, 1 hit
ProtoNetiSearch...

Entry informationi

Entry nameiA4GW50_RAT
AccessioniPrimary (citable) accession number: A4GW50
Secondary accession number(s): D4AA09
Entry historyiIntegrated into UniProtKB/TrEMBL: April 17, 2007
Last sequence update: April 17, 2007
Last modified: October 10, 2018
This is version 103 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Proteomics identificationCombined sources, Reference proteomeImported
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health

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