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UniProtKB - A4GW50 (A4GW50_RAT)
Protein
Submitted name:
RCG29601
Gene
Stk38l
Organism
Rattus norvegicus (Rat)
Status
Functioni
Sites
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Binding sitei | 119 | ATPPROSITE-ProRule annotation | 1 |
GO - Molecular functioni
- ATP binding Source: RGD
- magnesium ion binding Source: RGD
- protein serine/threonine kinase activity Source: RGD
GO - Biological processi
- intracellular signal transduction Source: RGD
- peptidyl-serine phosphorylation Source: GO_Central
- protein phosphorylation Source: RGD
- regulation of cellular component organization Source: RGD
Keywordsi
Molecular function | Kinase, Serine/threonine-protein kinaseUniRule annotationARBA annotation, Transferase |
Ligand | ATP-bindingPROSITE-ProRule annotationARBA annotation, Nucleotide-binding |
Names & Taxonomyi
Protein namesi | Submitted name: RCG29601ImportedSubmitted name: Serine/threonine kinase 38-likeImported |
Gene namesi | Name:Stk38lImported ORF Names:rCG_29601Imported |
Organismi | Rattus norvegicus (Rat)Imported |
Taxonomic identifieri | 10116 [NCBI] |
Taxonomic lineagei | Eukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Mammalia › Eutheria › Euarchontoglires › Glires › Rodentia › Myomorpha › Muroidea › Muridae › Murinae › Rattus |
Proteomesi |
|
Organism-specific databases
RGDi | 1564793, Stk38l |
Subcellular locationi
Cytoskeleton
- actin cytoskeleton Source: RGD
Cytosol
- cytosol Source: Ensembl
Other locations
- cytoplasm Source: RGD
Expressioni
Gene expression databases
Bgeei | ENSRNOG00000001828, Expressed in colon and 19 other tissues |
Interactioni
Binary interactionsi
A4GW50
With | #Exp. | IntAct |
---|---|---|
Mical1 [Q8VDP3] from Mus musculus. | 2 | EBI-4404035,EBI-4394891 |
Protein-protein interaction databases
IntActi | A4GW50, 1 interactor |
STRINGi | 10116.ENSRNOP00000002502 |
Structurei
Family & Domainsi
Domains and Repeats
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Domaini | 90 – 383 | Protein kinaseInterPro annotationAdd BLAST | 294 | |
Domaini | 384 – 453 | AGC-kinase C-terminalInterPro annotationAdd BLAST | 70 |
Sequence similaritiesi
Belongs to the protein kinase superfamily.UniRule annotation
Phylogenomic databases
eggNOGi | KOG0605, Eukaryota |
GeneTreei | ENSGT00940000153544 |
HOGENOMi | CLU_000288_67_0_1 |
OMAi | YTYKKSD |
OrthoDBi | 759391at2759 |
TreeFami | TF105337 |
Family and domain databases
InterProi | View protein in InterPro IPR000961, AGC-kinase_C IPR011009, Kinase-like_dom_sf IPR017892, Pkinase_C IPR000719, Prot_kinase_dom IPR017441, Protein_kinase_ATP_BS IPR008271, Ser/Thr_kinase_AS |
Pfami | View protein in Pfam PF00069, Pkinase, 1 hit PF00433, Pkinase_C, 1 hit |
SMARTi | View protein in SMART SM00220, S_TKc, 1 hit |
SUPFAMi | SSF56112, SSF56112, 1 hit |
PROSITEi | View protein in PROSITE PS51285, AGC_KINASE_CTER, 1 hit PS00107, PROTEIN_KINASE_ATP, 1 hit PS50011, PROTEIN_KINASE_DOM, 1 hit PS00108, PROTEIN_KINASE_ST, 1 hit |
i Sequence
Sequence statusi: Complete.
A4GW50-1 [UniParc]FASTAAdd to basket
10 20 30 40 50
MAMTAGATTT FPMSSHTRER VTVAKLTLEN FYSNLILQHE ERETRQKKLE
60 70 80 90 100
VAMEEEGLAD EEKKLRRSQH ARKETEFLRL KRTRLGLDDF ESLKVIGRGA
110 120 130 140 150
FGEVRLVQKK DTGHIYAMKI LRKADMLEKE QVAHIRAERD ILVEADGAWV
160 170 180 190 200
VKMFYSFQDK RNLYLIMEFL PGGDMMTLLM KKDTLTEEET QFYISETVLA
210 220 230 240 250
IDAIHQLGFI HRDIKPDNLL LDAKGHVKLS DFGLCTGLKK AHRTEFYRNL
260 270 280 290 300
THNPPSDFSF QNMNSKRKAE TWKKNRRQLA YSTVGTPDYI APEVFMQTGY
310 320 330 340 350
NKLCDWWSLG VIMYEMLIGF PPFCSETPQE TYRKVMSWKE TLAFPPEVPV
360 370 380 390 400
SEKAKDLILR FCTDSENRIG NGGVEEIKGH PFFEGVDWGH IRERPAAIPI
410 420 430 440 450
EIRSIDDTSN FDDFPESDIL QPVPNTTEPD YKSKDWVFLN YTYKRFEGLT
460
QRGSIPTYMK AGKL
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | AABR07062516 Genomic DNA No translation available. AABR07062517 Genomic DNA No translation available. AABR07062518 Genomic DNA No translation available. AABR07062519 Genomic DNA No translation available. AABR07062520 Genomic DNA No translation available. BC160812 mRNA Translation: AAI60812.1 EF444939 mRNA Translation: ABO26295.1 CH473964 Genomic DNA Translation: EDM01408.1 |
RefSeqi | NP_001076805.1, NM_001083336.1 XP_017448391.1, XM_017592902.1 |
Genome annotation databases
Ensembli | ENSRNOT00000002502; ENSRNOP00000002502; ENSRNOG00000001828 ENSRNOT00000086813; ENSRNOP00000068621; ENSRNOG00000001828 |
GeneIDi | 691337 |
KEGGi | rno:691337 |
UCSCi | RGD:1564793, rat |
Similar proteinsi
Cross-referencesi
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | AABR07062516 Genomic DNA No translation available. AABR07062517 Genomic DNA No translation available. AABR07062518 Genomic DNA No translation available. AABR07062519 Genomic DNA No translation available. AABR07062520 Genomic DNA No translation available. BC160812 mRNA Translation: AAI60812.1 EF444939 mRNA Translation: ABO26295.1 CH473964 Genomic DNA Translation: EDM01408.1 |
RefSeqi | NP_001076805.1, NM_001083336.1 XP_017448391.1, XM_017592902.1 |
3D structure databases
ModBasei | Search... |
SWISS-MODEL-Workspacei | Submit a new modelling project... |
Protein-protein interaction databases
IntActi | A4GW50, 1 interactor |
STRINGi | 10116.ENSRNOP00000002502 |
Genome annotation databases
Ensembli | ENSRNOT00000002502; ENSRNOP00000002502; ENSRNOG00000001828 ENSRNOT00000086813; ENSRNOP00000068621; ENSRNOG00000001828 |
GeneIDi | 691337 |
KEGGi | rno:691337 |
UCSCi | RGD:1564793, rat |
Organism-specific databases
CTDi | 23012 |
RGDi | 1564793, Stk38l |
Phylogenomic databases
eggNOGi | KOG0605, Eukaryota |
GeneTreei | ENSGT00940000153544 |
HOGENOMi | CLU_000288_67_0_1 |
OMAi | YTYKKSD |
OrthoDBi | 759391at2759 |
TreeFami | TF105337 |
Gene expression databases
Bgeei | ENSRNOG00000001828, Expressed in colon and 19 other tissues |
Family and domain databases
InterProi | View protein in InterPro IPR000961, AGC-kinase_C IPR011009, Kinase-like_dom_sf IPR017892, Pkinase_C IPR000719, Prot_kinase_dom IPR017441, Protein_kinase_ATP_BS IPR008271, Ser/Thr_kinase_AS |
Pfami | View protein in Pfam PF00069, Pkinase, 1 hit PF00433, Pkinase_C, 1 hit |
SMARTi | View protein in SMART SM00220, S_TKc, 1 hit |
SUPFAMi | SSF56112, SSF56112, 1 hit |
PROSITEi | View protein in PROSITE PS51285, AGC_KINASE_CTER, 1 hit PS00107, PROTEIN_KINASE_ATP, 1 hit PS50011, PROTEIN_KINASE_DOM, 1 hit PS00108, PROTEIN_KINASE_ST, 1 hit |
MobiDBi | Search... |
Entry informationi
Entry namei | A4GW50_RAT | |
Accessioni | A4GW50Primary (citable) accession number: A4GW50 Secondary accession number(s): D4AA09 | |
Entry historyi | Integrated into UniProtKB/TrEMBL: | April 17, 2007 |
Last sequence update: | April 17, 2007 | |
Last modified: | January 19, 2022 | |
This is version 124 of the entry and version 1 of the sequence. See complete history. | ||
Entry statusi | Unreviewed (UniProtKB/TrEMBL) |