Stk38l

Functionⁱ

Catalytic activityⁱ

ATP + a protein = ADP + a phosphoprotein.SAAS annotation

GO - Molecular functionⁱ

ATP binding Source: UniProtKB-KW
magnesium ion binding Source: Ensembl
protein serine/threonine kinase activity Source: GO_Central

View the complete GO annotation on QuickGO ...

GO - Biological processⁱ

intracellular signal transduction Source: GO_Central
peptidyl-serine phosphorylation Source: GO_Central
regulation of cellular component organization Source: Ensembl

View the complete GO annotation on QuickGO ...

Keywordsⁱ

Molecular function	Kinase, Serine/threonine-protein kinaseUniRule annotationSAAS annotation, Transferase
Ligand	ATP-bindingUniRule annotationSAAS annotation, Nucleotide-binding

Names & Taxonomyⁱ

Protein namesⁱ	Recommended name: Non-specific serine/threonine protein kinaseSAAS annotation (EC:2.7.11.1SAAS annotation)
Gene namesⁱ	Name:Stk38lImported ORF Names:rCG_29601Imported
Organismⁱ	Rattus norvegicus (Rat)Imported
Taxonomic identifierⁱ	10116 [NCBI]
Taxonomic lineageⁱ	cellular organisms › Eukaryota › Opisthokonta › Metazoa › Eumetazoa › Bilateria › Deuterostomia › Chordata › Craniata › Vertebrata › Gnathostomata › Teleostomi › Euteleostomi › Sarcopterygii › Dipnotetrapodomorpha › Tetrapoda › Amniota › Mammalia › Theria › Eutheria › Boreoeutheria › Euarchontoglires › Glires › Rodentia › Myomorpha › Muroidea › Muridae › Murinae › Rattus
Proteomesⁱ	UP000002494 Componentⁱ: Chromosome 4

Organism-specific databases

Rat genome database More...RGDⁱ	1564793 Stk38l

RGDⁱ

1564793 Stk38l

Subcellular locationⁱ

GO - Cellular component

Expressionⁱ

Gene expression databases

Bgeeⁱ	ENSRNOG00000001828 Expressed in 9 organ(s), highest expression level in colon

Bgeeⁱ

ENSRNOG00000001828 Expressed in 9 organ(s), highest expression level in colon

Interactionⁱ

Protein-protein interaction databases

IntActⁱ	A4GW50, 1 interactor
STRINGⁱ	10116.ENSRNOP00000002502

Family & Domainsⁱ

Domains and Repeats

Feature key	Position(s)	DescriptionActions	Graphical view	Length
Domainⁱ	90 – 383	Protein kinaseInterPro annotationAdd BLAST		294
Domainⁱ	384 – 453	AGC-kinase C-terminalInterPro annotationAdd BLAST		70

Sequence similaritiesⁱ

Belongs to the protein kinase superfamily.UniRule annotation

Phylogenomic databases

eggNOGⁱ	KOG0605 Eukaryota ENOG410XQC0 LUCA
Ensembl GeneTree More...GeneTreeⁱ	ENSGT00760000118994
HOVERGENⁱ	HBG104247
KEGG Orthology (KO) More...KOⁱ	K08790
OMAⁱ	NAIHLTM
TreeFamⁱ	TF105337

Family and domain databases

InterProⁱ	View protein in InterPro IPR000961 AGC-kinase_C IPR011009 Kinase-like_dom_sf IPR017892 Pkinase_C IPR000719 Prot_kinase_dom IPR017441 Protein_kinase_ATP_BS IPR008271 Ser/Thr_kinase_AS
Pfam protein domain database More...Pfamⁱ	View protein in Pfam PF00069 Pkinase, 1 hit PF00433 Pkinase_C, 1 hit
SMARTⁱ	View protein in SMART SM00220 S_TKc, 1 hit
SUPFAMⁱ	SSF56112 SSF56112, 2 hits
PROSITEⁱ	View protein in PROSITE PS51285 AGC_KINASE_CTER, 1 hit PS00107 PROTEIN_KINASE_ATP, 1 hit PS50011 PROTEIN_KINASE_DOM, 1 hit PS00108 PROTEIN_KINASE_ST, 1 hit

Sequenceⁱ

Sequence statusⁱ: Complete.

A4GW50-1 [UniParc]FASTA Add to basket

« Hide

        10         20         30         40         50
MAMTAGATTT FPMSSHTRER VTVAKLTLEN FYSNLILQHE ERETRQKKLE 
        60         70         80         90        100
VAMEEEGLAD EEKKLRRSQH ARKETEFLRL KRTRLGLDDF ESLKVIGRGA 
       110        120        130        140        150
FGEVRLVQKK DTGHIYAMKI LRKADMLEKE QVAHIRAERD ILVEADGAWV 
       160        170        180        190        200
VKMFYSFQDK RNLYLIMEFL PGGDMMTLLM KKDTLTEEET QFYISETVLA 
       210        220        230        240        250
IDAIHQLGFI HRDIKPDNLL LDAKGHVKLS DFGLCTGLKK AHRTEFYRNL 
       260        270        280        290        300
THNPPSDFSF QNMNSKRKAE TWKKNRRQLA YSTVGTPDYI APEVFMQTGY 
       310        320        330        340        350
NKLCDWWSLG VIMYEMLIGF PPFCSETPQE TYRKVMSWKE TLAFPPEVPV 
       360        370        380        390        400
SEKAKDLILR FCTDSENRIG NGGVEEIKGH PFFEGVDWGH IRERPAAIPI 
       410        420        430        440        450
EIRSIDDTSN FDDFPESDIL QPVPNTTEPD YKSKDWVFLN YTYKRFEGLT 
       460 
QRGSIPTYMK AGKL

Length:464

Mass (Da):53,759

Last modified:April 17, 2007 - v1

Checksum:ⁱA4441AA40093AF57

GO

Sequence databases

Select the link destinations: EMBLⁱ GenBankⁱ DDBJⁱ Links Updated	AABR07062516 Genomic DNA No translation available. AABR07062517 Genomic DNA No translation available. AABR07062518 Genomic DNA No translation available. AABR07062519 Genomic DNA No translation available. AABR07062520 Genomic DNA No translation available. BC160812 mRNA Translation: AAI60812.1 EF444939 mRNA Translation: ABO26295.1 CH473964 Genomic DNA Translation: EDM01408.1
NCBI Reference Sequences More...RefSeqⁱ	NP_001076805.1, NM_001083336.1 XP_017448391.1, XM_017592902.1
UniGeneⁱ	Rn.200326

Genome annotation databases

Ensemblⁱ	ENSRNOT00000002502; ENSRNOP00000002502; ENSRNOG00000001828 ENSRNOT00000086813; ENSRNOP00000068621; ENSRNOG00000001828
GeneIDⁱ	691337
KEGGⁱ	rno:691337
UCSC genome browser More...UCSCⁱ	RGD:1564793 rat

Protein	Similar proteins		Species	Score	Length	Source
A4GW50	Serine/threonine-protein kinase 38-like	)	HUMAN		464	UniRef90_Q9Y2H1
Serine/threonine-protein kinase 38-like		MOUSE		464
Non-specific serine/threonine protein kinase		PANTR		464
Non-specific serine/threonine protein kinase		PANPA		464
Non-specific serine/threonine protein kinase		GORGO		464
+306

Protein	Similar proteins		Species	Score	Length	Source
A4GW50	Serine/threonine-protein kinase 38-like	)	HUMAN		464	UniRef50_Q9Y2H1
Serine/threonine-protein kinase 38-like		MOUSE		464
Non-specific serine/threonine protein kinase		PANTR		464
Non-specific serine/threonine protein kinase		PANPA		464
Non-specific serine/threonine protein kinase		GORGO		464
+343

Cross-referencesⁱ

Sequence databases

Select the link destinations: EMBLⁱ GenBankⁱ DDBJⁱ Links Updated	AABR07062516 Genomic DNA No translation available. AABR07062517 Genomic DNA No translation available. AABR07062518 Genomic DNA No translation available. AABR07062519 Genomic DNA No translation available. AABR07062520 Genomic DNA No translation available. BC160812 mRNA Translation: AAI60812.1 EF444939 mRNA Translation: ABO26295.1 CH473964 Genomic DNA Translation: EDM01408.1
RefSeqⁱ	NP_001076805.1, NM_001083336.1 XP_017448391.1, XM_017592902.1
UniGeneⁱ	Rn.200326

3D structure databases

ModBaseⁱ	Search...
MobiDBⁱ	Search...

Protein-protein interaction databases

IntActⁱ	A4GW50, 1 interactor
STRINGⁱ	10116.ENSRNOP00000002502

Protocols and materials databases

Structural Biology Knowledgebase	Search...

Structural Biology Knowledgebase

Search...

Genome annotation databases

Ensemblⁱ	ENSRNOT00000002502; ENSRNOP00000002502; ENSRNOG00000001828 ENSRNOT00000086813; ENSRNOP00000068621; ENSRNOG00000001828
GeneIDⁱ	691337
KEGGⁱ	rno:691337
UCSCⁱ	RGD:1564793 rat

Organism-specific databases

CTDⁱ	23012
RGDⁱ	1564793 Stk38l

Phylogenomic databases

eggNOGⁱ	KOG0605 Eukaryota ENOG410XQC0 LUCA
GeneTreeⁱ	ENSGT00760000118994
HOVERGENⁱ	HBG104247
KOⁱ	K08790
OMAⁱ	NAIHLTM
TreeFamⁱ	TF105337

Gene expression databases

Bgeeⁱ	ENSRNOG00000001828 Expressed in 9 organ(s), highest expression level in colon

Bgeeⁱ

ENSRNOG00000001828 Expressed in 9 organ(s), highest expression level in colon

Family and domain databases

InterProⁱ	View protein in InterPro IPR000961 AGC-kinase_C IPR011009 Kinase-like_dom_sf IPR017892 Pkinase_C IPR000719 Prot_kinase_dom IPR017441 Protein_kinase_ATP_BS IPR008271 Ser/Thr_kinase_AS
Pfamⁱ	View protein in Pfam PF00069 Pkinase, 1 hit PF00433 Pkinase_C, 1 hit
SMARTⁱ	View protein in SMART SM00220 S_TKc, 1 hit
SUPFAMⁱ	SSF56112 SSF56112, 2 hits
PROSITEⁱ	View protein in PROSITE PS51285 AGC_KINASE_CTER, 1 hit PS00107 PROTEIN_KINASE_ATP, 1 hit PS50011 PROTEIN_KINASE_DOM, 1 hit PS00108 PROTEIN_KINASE_ST, 1 hit
ProtoNetⁱ	Search...

Entry informationⁱ

Entry nameⁱ	A4GW50_RAT
Accessionⁱ	A4GW50Primary (citable) accession number: A4GW50 Secondary accession number(s): D4AA09
Entry historyⁱ	Integrated into UniProtKB/TrEMBL:	April 17, 2007
	Last sequence update:	April 17, 2007
	Last modified:	October 10, 2018
	This is version 103 of the entry and version 1 of the sequence. See complete history.
Entry statusⁱ	Unreviewed (UniProtKB/TrEMBL)

Miscellaneousⁱ

Keywords - Technical termⁱ

Complete proteome, Proteomics identificationCombined sources, Reference proteomeImported

UniProtKB

UniParc

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UniRef

Proteomes

Annotation systems

Supporting data

UniProtKB - A4GW50 (A4GW50_RAT)

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Non-specific serine/threonine protein kinase

Select a section on the left to see content.

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

GO - Biological processi

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

Organism-specific databases

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Cytoskeleton

Cytosol

Other locations

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

Gene expression databases

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

Protein-protein interaction databases

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Domains and Repeats

<p>This subsection of the ‘Family and domains’ section provides information about the sequence similarity with other proteins.<p><a href='/help/sequence_similarities' target='_top'>More...</a></p>Sequence similaritiesi

Phylogenomic databases

Family and domain databases

Sequence databases

Genome annotation databases

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

3D structure databases

Protein-protein interaction databases

Protocols and materials databases

Genome annotation databases

Organism-specific databases

Phylogenomic databases

Gene expression databases

Family and domain databases

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This section contains any relevant information that doesn’t fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

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Functionⁱ

GO - Molecular functionⁱ

GO - Biological processⁱ

Names & Taxonomyⁱ

Subcellular locationⁱ

Expressionⁱ

Interactionⁱ

Family & Domainsⁱ

Sequence similaritiesⁱ

Cross-referencesⁱ

Entry informationⁱ

Miscellaneousⁱ

Keywords - Technical termⁱ