Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Entry version 37 (12 Aug 2020)
Sequence version 1 (17 Apr 2007)
Previous versions | rss
Help videoAdd a publicationFeedback
Protein

Protein TIC 214

Gene

TIC214

Organism
Phaseolus vulgaris (Kidney bean) (French bean)
Status
Reviewed-Annotation score:

Annotation score:2 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Protein inferred from homologyi <p>This indicates the type of evidence that supports the existence of the protein. Note that the 'protein existence' evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

Involved in protein precursor import into chloroplasts. May be part of an intermediate translocation complex acting as a protein-conducting channel at the inner envelope.By similarity

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Biological processi

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywordsi

Biological processProtein transport, Transport

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Recommended name:
Protein TIC 214By similarity
Alternative name(s):
Translocon at the inner envelope membrane of chloroplasts 214By similarity
Short name:
AtTIC214By similarity
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: 'Name', 'Synonyms', 'Ordered locus names' and 'ORF names'.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:TIC214By similarity
Synonyms:ycf1
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section indicates if the gene coding for the protein originates from the hydrogenosome, the mitochondrion, the nucleomorph, different plastids or a plasmid. The absence of this section means that the gene is located in one of the main chromosomal element(s).<p><a href='/help/encoded_on' target='_top'>More...</a></p>Encoded oniPlastid; Chloroplast
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiPhaseolus vulgaris (Kidney bean) (French bean)
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the 'taxonomic identifier' or 'taxid'.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri3885 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryotaViridiplantaeStreptophytaEmbryophytaTracheophytaSpermatophytaMagnoliopsidaeudicotyledonsGunneridaePentapetalaerosidsfabidsFabalesFabaceaePapilionoideae50 kb inversion cladeNPAAA cladeindigoferoid/millettioid cladePhaseoleaePhaseolus

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cell wall Cytoskeleton Vacuole Chloroplast Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertion Graphics by Christian Stolte & Seán O’Donoghue; Source: COMPARTMENTS

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/subcellular%5Flocation%5Fsection">'Subcellular location'</a> section describes the extent of a membrane-spanning region of the protein. It denotes the presence of both alpha-helical transmembrane regions and the membrane spanning regions of beta-barrel transmembrane proteins.<p><a href='/help/transmem' target='_top'>More...</a></p>Transmembranei23 – 45HelicalSequence analysisAdd BLAST23
Transmembranei64 – 84HelicalSequence analysisAdd BLAST21
Transmembranei129 – 149HelicalSequence analysisAdd BLAST21
Transmembranei172 – 192HelicalSequence analysisAdd BLAST21
Transmembranei221 – 241HelicalSequence analysisAdd BLAST21

Keywords - Cellular componenti

Chloroplast, Membrane, Plastid, Plastid inner membrane

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'PTM / Processing' section describes the extent of a polypeptide chain in the mature protein following processing or proteolytic cleavage.<p><a href='/help/chain' target='_top'>More...</a></p>ChainiPRO_00003265841 – 1759Protein TIC 214Add BLAST1759

Proteomic databases

PRoteomics IDEntifications database

More...
PRIDEi
A4GGF4

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

<p>This subsection of the <a href="http://www.uniprot.org/help/interaction%5Fsection">'Interaction'</a> section provides information about the protein quaternary structure and interaction(s) with other proteins or protein complexes (with the exception of physiological receptor-ligand interactions which are annotated in the <a href="http://www.uniprot.org/help/function%5Fsection">'Function'</a> section).<p><a href='/help/subunit_structure' target='_top'>More...</a></p>Subunit structurei

Part of the Tic complex.

By similarity

Protein-protein interaction databases

STRING: functional protein association networks

More...
STRINGi
3885.XP_007142843.1

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Compositional bias

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Family and Domains' section describes the position of regions of compositional bias within the protein and the particular amino acids that are over-represented within those regions.<p><a href='/help/compbias' target='_top'>More...</a></p>Compositional biasi867 – 1098Lys-richAdd BLAST232
Compositional biasi1570 – 1648Lys-richAdd BLAST79

<p>This subsection of the 'Family and domains' section provides information about the sequence similarity with other proteins.<p><a href='/help/sequence_similarities' target='_top'>More...</a></p>Sequence similaritiesi

Belongs to the TIC214 family.Curated

Keywords - Domaini

Transmembrane, Transmembrane helix

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

More...
eggNOGi
ENOG502QSDY, Eukaryota

Family and domain databases

Integrated resource of protein families, domains and functional sites

More...
InterProi
View protein in InterPro
IPR008896, TIC214

The PANTHER Classification System

More...
PANTHERi
PTHR33163, PTHR33163, 2 hits

Pfam protein domain database

More...
Pfami
View protein in Pfam
PF05758, Ycf1, 2 hits

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence%5Flength">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequencei

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences%5Fsection">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

A4GGF4-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MIFESFILEN LVFLCMKIMN SIVVVGLYYG FMTTFSIGPS YLFLLRARLV
60 70 80 90 100
EEGTENKISA TTGFITGQLI IFMSIYYAPL HLALGRPHTI TVIAIPYLLF
110 120 130 140 150
QFFGNSKKNF LNYGYKNPNS IRNFSIQRIF FQNLLFQFFN PLFLPSSIFM
160 170 180 190 200
RFVNIYLFRC NNKVLFLTSS FIGWIIGHTF FMKWIEFLLI CIQQNNLIKS
210 220 230 240 250
NVRIQSNKYI LSELKNSMFQ IFVVFLFVTC LYYLGRIPPP FFSKKLLEIK
260 270 280 290 300
ESNEFFKKEK KGDVETNLQR IRTKQKRSNN KDIFPSIFLK KEKNLYKLDE
310 320 330 340 350
QKNKLQKPLL NILFNYKRWN RPFRYIKNNQ FENIIKNEIS EFFFHTYPRN
360 370 380 390 400
GREKIYFTYP QNLSTFQKMM ETKIDIFTIK KISYDDSSNH SSYSNEEKRK
410 420 430 440 450
KLSNEFITRT KLIDKELISL DIFENRIRLC NDETKKNYFT KITDPFLNGP
460 470 480 490 500
FRGRIKKGFS TSIQDEKTYK KNHILINKIQ EIFLYNSKKI PKKNNRNYQK
510 520 530 540 550
LEENLKTFNK KLLVTTFLFN LISQFSKKSV SSFNYEVLYL FPEHEQVKMN
560 570 580 590 600
SNLEEEKKLI IKILFDAITT DLNEKTKGNR NNTKSIKINE ICKKVPRWSY
610 620 630 640 650
KFMDELEELG GKMEADNSQI RSRKAKRVVI LTNKSKFFKK YNTYNDLGDT
660 670 680 690 700
ENTENTEKKN ELALRRYSQQ SDFRRDIIKG SIRAQRRKTV TWKFFQKRVH
710 720 730 740 750
SPLFLDKIEK SLFFSFDTFK SMKIFLKLKI WIRKKTEFKI LGYIEEKTKK
760 770 780 790 800
SPKKEEEKKK GNEERKRIEI AEAWDSIIFA QVIRGVLLIT QCIIRKYILL
810 820 830 840 850
PSLIIIKNMI RILFFQIPEW SEDYRDWKRE RYIKCTYNGV QLSEREFPQK
860 870 880 890 900
WLTDGIQIKI VFPFHLKPWH KYKIRCNKKK KDSKKKKNFC FLTVWGMEVE
910 920 930 940 950
LPFSSSPKNL FSFFDPILKE LKKKTKQFEF FTFRVLKVFS EKFKLFLNIV
960 970 980 990 1000
IEKAKWIINR IMESLKKSIV FLTKKRKEFF ESLFIQWKPK KLDELSENKI
1010 1020 1030 1040 1050
DEATISIQSI KSTNFALKKK KIKDLNTKRK VVIKKIKKLK KEEKKRGLVI
1060 1070 1080 1090 1100
SETNIDSNKT ISDSKRIEFE KKNLQILKRI HIRLTKKSHS FLKFFIKKIY
1110 1120 1130 1140 1150
LDIFLYIICI PKIHIQPFIE STKKFLNKWI YGNETNAERT YKTNQSIIPF
1160 1170 1180 1190 1200
ISKLHKYFHN RNLNSHNYFD VSFLSQAYVF FNLLQTRIIN INIYKLRLLF
1210 1220 1230 1240 1250
EYHKNFFFVK NKIKNSFFGA QGIVHSKLEQ KNLLNSKRNQ WTNWLKNHYY
1260 1270 1280 1290 1300
QYDLSNSRWS KLLSQKWRNR ITKFGVAQNP NLTKWDSYGK SPLIIYKEQQ
1310 1320 1330 1340 1350
GAALKKKIRK QYRYDLLSYN FMNYANKKDS YIYGYRSLFQ SNKNIWISSN
1360 1370 1380 1390 1400
YNTYKKNLFD RISNIFIKNY EDAIIIDIEK NSNRKYLDWM GIHREILNRS
1410 1420 1430 1440 1450
ISNPEFWFFS KFVIFYNAYR SNSQIIPIKL LYLHSKVSKV NKNVSEKNIT
1460 1470 1480 1490 1500
RKKKRIAVFR ASKKQEDIEK NSVAVGRGSE KNSYVIKKKK VKNNMEVELH
1510 1520 1530 1540 1550
FLVRNFLIFH FNWKNFLGQN IFHNVKVYCL LIRLTNLRKM TIASIQRGEL
1560 1570 1580 1590 1600
GLDIMIIQNQ KNLTLPGLSK NKNNKLRKKE LFVIEPVRLS RKNNKQFLKS
1610 1620 1630 1640 1650
KTMDLSLIHK NKRKIDKKYL KKIHVNKKSF YKYITRTRDQ KITEKNEKEI
1660 1670 1680 1690 1700
LNFLVPENIL SARRRRELRM RICLYPNNRN SIHRNTIFDN ENKVKKGFQV
1710 1720 1730 1740 1750
LTKKRNEKEK KKLMNFKIFL WPKYRLEDLA CINRYWFNTH NGSRFSIVRI

HLYPRVKIC
Length:1,759
Mass (Da):211,957
Last modified:April 17, 2007 - v1
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:i2D1D26836FBDDF58
GO

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Sequence' section reports difference(s) between the canonical sequence (displayed by default in the entry) and the different sequence submissions merged in the entry. These various submissions may originate from different sequencing projects, different types of experiments, or different biological samples. Sequence conflicts are usually of unknown origin.<p><a href='/help/conflict' target='_top'>More...</a></p>Sequence conflicti752 – 757PKKEEE → TEKRGG in ABW22810 (Ref. 2) Curated6

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...
EMBLi

GenBank nucleotide sequence database

More...
GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...
DDBJi
Links Updated
DQ886273 Genomic DNA Translation: ABH88136.1
EU196765 Genomic DNA Translation: ABW22810.1

NCBI Reference Sequences

More...
RefSeqi
YP_001122855.1, NC_009259.1

Genome annotation databases

Ensembl plant genome annotation project

More...
EnsemblPlantsi
ESW14837; ESW14837; PHAVU_007G021600g

Database of genes from NCBI RefSeq genomes

More...
GeneIDi
4961793

Gramene; a comparative resource for plants

More...
Gramenei
ESW14837; ESW14837; PHAVU_007G021600g

KEGG: Kyoto Encyclopedia of Genes and Genomes

More...
KEGGi
pvu:PhvuCp73

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
DQ886273 Genomic DNA Translation: ABH88136.1
EU196765 Genomic DNA Translation: ABW22810.1
RefSeqiYP_001122855.1, NC_009259.1

3D structure databases

Database of comparative protein structure models

More...
ModBasei
Search...

SWISS-MODEL Interactive Workspace

More...
SWISS-MODEL-Workspacei
Submit a new modelling project...

Protein-protein interaction databases

STRINGi3885.XP_007142843.1

Proteomic databases

PRIDEiA4GGF4

Genome annotation databases

EnsemblPlantsiESW14837; ESW14837; PHAVU_007G021600g
GeneIDi4961793
GrameneiESW14837; ESW14837; PHAVU_007G021600g
KEGGipvu:PhvuCp73

Phylogenomic databases

eggNOGiENOG502QSDY, Eukaryota

Family and domain databases

InterProiView protein in InterPro
IPR008896, TIC214
PANTHERiPTHR33163, PTHR33163, 2 hits
PfamiView protein in Pfam
PF05758, Ycf1, 2 hits

ProtoNet; Automatic hierarchical classification of proteins

More...
ProtoNeti
Search...

MobiDB: a database of protein disorder and mobility annotations

More...
MobiDBi
Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the 'Entry information' section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiTI214_PHAVU
<p>This subsection of the 'Entry information' section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called 'Primary (citable) accession number'.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: A4GGF4
Secondary accession number(s): A8W840
<p>This subsection of the 'Entry information' section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification ('Last modified'). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/Swiss-Prot: April 8, 2008
Last sequence update: April 17, 2007
Last modified: August 12, 2020
This is version 37 of the entry and version 1 of the sequence. See complete history.
<p>This subsection of the 'Entry information' section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programPlant Protein Annotation Program

<p>This section contains any relevant information that doesn't fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Documents

  1. SIMILARITY comments
    Index of protein domains and families
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health

We'd like to inform you that we have updated our Privacy Notice to comply with Europe’s new General Data Protection Regulation (GDPR) that applies since 25 May 2018.

Do not show this banner again