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Protein
Submitted name:

KCNF1 protein

Gene

KCNF1

Organism
Bos taurus (Bovine)
Status
Unreviewed-Annotation score: -Experimental evidence at transcript leveli

Functioni

GO - Molecular functioni

  • voltage-gated potassium channel activity Source: GO_Central

GO - Biological processi

Keywordsi

Molecular functionIon channel, Potassium channelSAAS annotation, Voltage-gated channelSAAS annotation
Biological processIon transport, Potassium transport, Transport
LigandPotassium

Enzyme and pathway databases

ReactomeiR-BTA-1296072 Voltage gated Potassium channels

Names & Taxonomyi

Protein namesi
Submitted name:
KCNF1 proteinImported
Submitted name:
Potassium voltage-gated channel modifier subfamily F member 1Imported
Gene namesi
Name:KCNF1Imported
OrganismiBos taurus (Bovine)Imported
Taxonomic identifieri9913 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaLaurasiatheriaCetartiodactylaRuminantiaPecoraBovidaeBovinaeBos
Proteomesi
  • UP000009136 Componenti: Chromosome 11

Organism-specific databases

VGNCiVGNC:30441 KCNF1

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Transmembranei183 – 204HelicalSequence analysisAdd BLAST22
Transmembranei248 – 270HelicalSequence analysisAdd BLAST23
Transmembranei324 – 341HelicalSequence analysisAdd BLAST18
Transmembranei385 – 406HelicalSequence analysisAdd BLAST22

Keywords - Cellular componenti

Membrane

Expressioni

Gene expression databases

BgeeiENSBTAG00000021283 Expressed in 4 organ(s), highest expression level in brain

Interactioni

Protein-protein interaction databases

STRINGi9913.ENSBTAP00000028357

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini25 – 126BTB_2InterPro annotationAdd BLAST102
Domaini182 – 415Ion_transInterPro annotationAdd BLAST234

Coiled coil

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Coiled coili131 – 151Sequence analysisAdd BLAST21

Sequence similaritiesi

Belongs to the potassium channel family.SAAS annotation

Keywords - Domaini

Coiled coilSequence analysis, Transmembrane, Transmembrane helixSequence analysisSAAS annotation

Phylogenomic databases

eggNOGiKOG3713 Eukaryota
COG1226 LUCA
GeneTreeiENSGT00760000118981
HOGENOMiHOG000231016
HOVERGENiHBG052230
KOiK04899
OMAiNEMEFWK
OrthoDBiEOG091G0FP3
TreeFamiTF313103

Family and domain databases

Gene3Di1.20.120.350, 1 hit
InterProiView protein in InterPro
IPR005821 Ion_trans_dom
IPR003968 K_chnl_volt-dep_Kv
IPR003971 K_chnl_volt-dep_Kv9
IPR011333 SKP1/BTB/POZ_sf
IPR003131 T1-type_BTB
IPR028325 VG_K_chnl
IPR027359 Volt_channel_dom_sf
PANTHERiPTHR11537 PTHR11537, 1 hit
PfamiView protein in Pfam
PF02214 BTB_2, 1 hit
PF00520 Ion_trans, 1 hit
PRINTSiPR00169 KCHANNEL
PR01494 KV9CHANNEL
PR01491 KVCHANNEL
SUPFAMiSSF54695 SSF54695, 1 hit

Sequencei

Sequence statusi: Complete.

A4FV89-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MDGTGERSLP EPGSQDSRAD DDIEIVVNVG GVRQVLYGDL LSRYPETRLA
60 70 80 90 100
ELIHCLAGGY DTIFSLCDDY DPGKREFYFD RDPDAFKCVI EVYYFGEVHM
110 120 130 140 150
KKGICPICFK NEMDFWKVDL KFLDDCCKSH LSEKREELEE IARRVQLILD
160 170 180 190 200
DLGVDTAEGR WQRCQKCVWK FLEKPESSCP ARVVAVLSFL LILVSSVVMC
210 220 230 240 250
MGTIPELQVL DAEGNRVEHP TLENVETACI GWFTLEYLLR LFSSPNKLHF
260 270 280 290 300
ALSFMNIVDV LAILPFYVSL TLTHLGARMM ELTNVQQAVQ ALRIMRIARI
310 320 330 340 350
FKLARHSSGL QTLTYALKRS FKELGLLLMY LAVGIFVFSA LGYTMEQSHP
360 370 380 390 400
ETLFKSIPQS FWWAIITMTT VGYGDIYPKT TLGKLNAAIS FLCGVIAIAL
410 420 430 440 450
PIHPIINNFV RYYNKQRVLE TAARHELELM ELNSGTAGEG KAGGSRGDLD
460 470 480 490
HLPPPEPAGK EDPSWSSRLK LSHSDTFIPL LTEEKHHRTR LQSCK
Length:495
Mass (Da):56,006
Last modified:April 17, 2007 - v1
Checksum:iFAE5795AC54B26BD
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
DAAA02031921 Genomic DNA No translation available.
BC123875 mRNA Translation: AAI23876.1
RefSeqiNP_001091456.1, NM_001097987.1
UniGeneiBt.26324

Genome annotation databases

EnsembliENSBTAT00000028357; ENSBTAP00000028357; ENSBTAG00000021283
GeneIDi505879
KEGGibta:505879

Similar proteinsi

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
DAAA02031921 Genomic DNA No translation available.
BC123875 mRNA Translation: AAI23876.1
RefSeqiNP_001091456.1, NM_001097987.1
UniGeneiBt.26324

3D structure databases

ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi9913.ENSBTAP00000028357

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENSBTAT00000028357; ENSBTAP00000028357; ENSBTAG00000021283
GeneIDi505879
KEGGibta:505879

Organism-specific databases

CTDi3754
VGNCiVGNC:30441 KCNF1

Phylogenomic databases

eggNOGiKOG3713 Eukaryota
COG1226 LUCA
GeneTreeiENSGT00760000118981
HOGENOMiHOG000231016
HOVERGENiHBG052230
KOiK04899
OMAiNEMEFWK
OrthoDBiEOG091G0FP3
TreeFamiTF313103

Enzyme and pathway databases

ReactomeiR-BTA-1296072 Voltage gated Potassium channels

Gene expression databases

BgeeiENSBTAG00000021283 Expressed in 4 organ(s), highest expression level in brain

Family and domain databases

Gene3Di1.20.120.350, 1 hit
InterProiView protein in InterPro
IPR005821 Ion_trans_dom
IPR003968 K_chnl_volt-dep_Kv
IPR003971 K_chnl_volt-dep_Kv9
IPR011333 SKP1/BTB/POZ_sf
IPR003131 T1-type_BTB
IPR028325 VG_K_chnl
IPR027359 Volt_channel_dom_sf
PANTHERiPTHR11537 PTHR11537, 1 hit
PfamiView protein in Pfam
PF02214 BTB_2, 1 hit
PF00520 Ion_trans, 1 hit
PRINTSiPR00169 KCHANNEL
PR01494 KV9CHANNEL
PR01491 KVCHANNEL
SUPFAMiSSF54695 SSF54695, 1 hit
ProtoNetiSearch...

Entry informationi

Entry nameiA4FV89_BOVIN
AccessioniPrimary (citable) accession number: A4FV89
Entry historyiIntegrated into UniProtKB/TrEMBL: April 17, 2007
Last sequence update: April 17, 2007
Last modified: November 7, 2018
This is version 92 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health

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