UniProtKB - A4FU65 (A4FU65_HUMAN)
Protein
Glycylpeptide N-tetradecanoyltransferase
Gene
NMT1
Organism
Homo sapiens (Human)
Status
Functioni
Adds a myristoyl group to the N-terminal glycine residue of certain cellular proteins.UniRule annotation
Catalytic activityi
- N-terminal glycyl-[protein] + tetradecanoyl-CoA = CoA + H+ + N-tetradecanoylglycyl-[protein]UniRule annotationEC:2.3.1.97UniRule annotation
GO - Molecular functioni
- glycylpeptide N-tetradecanoyltransferase activity Source: UniProtKB-EC
GO - Biological processi
- N-terminal protein myristoylation Source: InterPro
Keywordsi
Molecular function | AcyltransferaseUniRule annotation, Transferase |
Names & Taxonomyi
Protein namesi | Recommended name: Glycylpeptide N-tetradecanoyltransferaseUniRule annotation (EC:2.3.1.97UniRule annotation) |
Gene namesi | Name:NMT1Imported |
Organismi | Homo sapiens (Human)Imported |
Taxonomic identifieri | 9606 [NCBI] |
Taxonomic lineagei | Eukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Mammalia › Eutheria › Euarchontoglires › Primates › Haplorrhini › Catarrhini › Hominidae › Homo |
Family & Domainsi
Domains and Repeats
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Domaini | 3 – 111 | NMT_CInterPro annotationAdd BLAST | 109 |
Sequence similaritiesi
Belongs to the NMT family.UniRule annotation
Family and domain databases
InterProi | View protein in InterPro IPR016181, Acyl_CoA_acyltransferase IPR000903, MyristoylCoA_TrFase IPR022677, MyristoylCoA_TrFase_C |
PANTHERi | PTHR11377, PTHR11377, 1 hit |
Pfami | View protein in Pfam PF02799, NMT_C, 1 hit |
SUPFAMi | SSF55729, SSF55729, 1 hit |
i Sequence
Sequence statusi: Fragment.
A4FU65-1 [UniParc]FASTAAdd to basket
10 20 30 40 50
YWAGLRPMET KDIPVVHQLL TRYLKQFHLT PVMSQEEVEH WFYPQENIID
60 70 80 90 100
TFVVENANGE VTDFLSFYTL PSTIMNHPTH KSLKAAYSFY NVHTQTPLLD
110 120 130 140 150
LMSDALVLAK MVRSRRGGLW RCAGKGQWSH GEHSSRDAAS HGLEALSPPH
160 170 180
LFCLGRVPAV FRQKLKTWRE QGASEVKALN SS
Experimental Info
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Non-terminal residuei | 1 | Imported | 1 |
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | BC109226 mRNA Translation: AAI09227.1 |
Similar proteinsi
Cross-referencesi
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | BC109226 mRNA Translation: AAI09227.1 |
3D structure databases
ModBasei | Search... |
SWISS-MODEL-Workspacei | Submit a new modelling project... |
Proteomic databases
MaxQBi | A4FU65 |
PeptideAtlasi | A4FU65 |
Miscellaneous databases
ChiTaRSi | NMT1, human |
Family and domain databases
InterProi | View protein in InterPro IPR016181, Acyl_CoA_acyltransferase IPR000903, MyristoylCoA_TrFase IPR022677, MyristoylCoA_TrFase_C |
PANTHERi | PTHR11377, PTHR11377, 1 hit |
Pfami | View protein in Pfam PF02799, NMT_C, 1 hit |
SUPFAMi | SSF55729, SSF55729, 1 hit |
ProtoNeti | Search... |
MobiDBi | Search... |
Entry informationi
Entry namei | A4FU65_HUMAN | |
Accessioni | A4FU65Primary (citable) accession number: A4FU65 | |
Entry historyi | Integrated into UniProtKB/TrEMBL: | April 17, 2007 |
Last sequence update: | April 17, 2007 | |
Last modified: | October 7, 2020 | |
This is version 54 of the entry and version 1 of the sequence. See complete history. | ||
Entry statusi | Unreviewed (UniProtKB/TrEMBL) | |
Disclaimer | Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care. |