UniProtKB - A4FU51 (A4FU51_HUMAN)
Protein
Submitted name:
NMDA receptor regulated 1-like
Gene
NARG1L
Organism
Homo sapiens (Human)
Status
Names & Taxonomyi
Protein namesi | Submitted name: NMDA receptor regulated 1-likeImportedSubmitted name: NMDA receptor regulated 1-like, isoform CRA_cImportedSubmitted name: cDNA FLJ77538, highly similar to Homo sapiens NMDA receptor regulated 1-like (NARG1L), transcript variant 1, mRNAImported |
Gene namesi | Name:NARG1LImported ORF Names:hCG_2020106Imported |
Organismi | Homo sapiens (Human)Imported |
Taxonomic identifieri | 9606 [NCBI] |
Taxonomic lineagei | Eukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Mammalia › Eutheria › Euarchontoglires › Primates › Haplorrhini › Catarrhini › Hominidae › Homo |
Organism-specific databases
EuPathDBi | HostDB:ENSG00000172766.18 |
Subcellular locationi
Cytosol
- cytosol Source: HPA
Expressioni
Gene expression databases
Bgeei | ENSG00000172766, Expressed in sural nerve and 235 other tissues |
Family & Domainsi
Domains and Repeats
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Domaini | 46 – 181 | TPR_REGIONInterPro annotationAdd BLAST | 136 | |
Repeati | 46 – 79 | TPRPROSITE-ProRule annotationAdd BLAST | 34 | |
Repeati | 80 – 113 | TPRPROSITE-ProRule annotationAdd BLAST | 34 | |
Domaini | 224 – 257 | TPR_REGIONInterPro annotationAdd BLAST | 34 | |
Repeati | 224 – 257 | TPRPROSITE-ProRule annotationAdd BLAST | 34 | |
Domaini | 374 – 441 | TPR_REGIONInterPro annotationAdd BLAST | 68 | |
Repeati | 374 – 407 | TPRPROSITE-ProRule annotationAdd BLAST | 34 | |
Repeati | 408 – 441 | TPRPROSITE-ProRule annotationAdd BLAST | 34 |
Region
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Regioni | 603 – 638 | DisorderedSequence analysisAdd BLAST | 36 |
Keywords - Domaini
RepeatARBA annotation, TPR repeatPROSITE-ProRule annotationARBA annotationPhylogenomic databases
HOGENOMi | CLU_006686_0_0_1 |
OMAi | VNHTAIN |
OrthoDBi | 792708at2759 |
Family and domain databases
InterProi | View protein in InterPro IPR021183, NatA_aux_su IPR013026, TPR-contain_dom IPR011990, TPR-like_helical_dom_sf IPR013105, TPR_2 IPR019734, TPR_repeat |
Pfami | View protein in Pfam PF12569, NARP1, 1 hit PF07719, TPR_2, 1 hit |
PIRSFi | PIRSF000422, N-terminal-AcTrfase-A_aux_su, 1 hit |
SMARTi | View protein in SMART SM00028, TPR, 6 hits |
SUPFAMi | SSF48452, SSF48452, 1 hit |
PROSITEi | View protein in PROSITE PS50005, TPR, 5 hits PS50293, TPR_REGION, 3 hits |
i Sequence
Sequence statusi: Complete.
A4FU51-1 [UniParc]FASTAAdd to basket
10 20 30 40 50
MPNVLLPPKE SNLFKRILKC YEQKQYKNGL KFCKMILSNP KFAEHGETLA
60 70 80 90 100
MKGLTLNCLG KKEEAYEFVR KGLRNDVKSH VCWHVYGLLQ RSDKKYDEAI
110 120 130 140 150
KCYRNALKLD KDNLQILRDL SLLQIQMRDL EGYRETRYQL LQLRPTQRAS
160 170 180 190 200
WIGYAIAYHL LKDYDMALKL LEEFRQTQQV PPNKIDYEYS ELILYQNQVM
210 220 230 240 250
READLLQESL EHIEMYEKQI CDKLLVEEIK GEILLKLGRL KEASEVFKNL
260 270 280 290 300
IDRNAENWCY YEGLEKALQI STLEERLQIY EEISKQHPKA ITPRRLPLTL
310 320 330 340 350
VPGERFRELM DKFLRVNFSK GCPPLFTTLK SLYYNTEKVS IIQELVTNYE
360 370 380 390 400
ASLKTCDFFS PYENGEKEPP TTLLWVQYFL AQHFDKLGQY SLALDYINAA
410 420 430 440 450
IASTPTLIEL FYMKAKIYKH IGNLKEAAKW MDEAQSLDTA DRFINSKCAK
460 470 480 490 500
YMLRANMIKE AEEMCSKFTR EGTSAMENLN EMQCMWFQTE CISAYQRLGR
510 520 530 540 550
YGDALKKCHE VERHFFEITD DQFDFHTYCM RKMTLRAYVD LLRLEDILRR
560 570 580 590 600
HAFYFKAARS AIEIYLKLYD NPLTNESKQQ EINSENLSAK ELKKMLSKQR
610 620 630 640 650
RAQKKAKLEE ERKHAERERQ QKNQKKKRDE EEEEASGLKE ELIPEKLERV
660 670 680 690 700
ENPLEEAVKF LIPLKNLVAD NIDTHLLAFE IYFRKGKFLL MLQSVKRAFA
710 720 730 740 750
INSNNPWLHE CLIRFSKSVS NHSNLPDIVS KVLSQEMQKI FVKKDLESFN
760 770 780 790 800
EDFLKRNATS LQHLLSGAKM MYFLDKSRQE KAIAIATRLD ETIKDKDVKT
810 820 830 840 850
LIKVSEALLD GSFGNCSSQY EEYRMACHNL LPFTSAFLPA VNEVDNPNVA
860
LNHTANYDVL ANEI
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | BC101719 mRNA Translation: AAI01720.1 BC101721 mRNA Translation: AAI01722.1 AK291248 mRNA Translation: BAF83937.1 CH471075 Genomic DNA Translation: EAX08656.1 |
RefSeqi | NP_078837.3, NM_024561.4 |
Genome annotation databases
GeneIDi | 79612 |
KEGGi | hsa:79612 |
Similar proteinsi
Cross-referencesi
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | BC101719 mRNA Translation: AAI01720.1 BC101721 mRNA Translation: AAI01722.1 AK291248 mRNA Translation: BAF83937.1 CH471075 Genomic DNA Translation: EAX08656.1 |
RefSeqi | NP_078837.3, NM_024561.4 |
3D structure databases
SMRi | A4FU51 |
ModBasei | Search... |
Protocols and materials databases
Antibodypediai | 23410, 59 antibodies |
DNASUi | 79612 |
Genome annotation databases
GeneIDi | 79612 |
KEGGi | hsa:79612 |
Organism-specific databases
CTDi | 79612 |
EuPathDBi | HostDB:ENSG00000172766.18 |
PharmGKBi | PA165505266 |
Phylogenomic databases
HOGENOMi | CLU_006686_0_0_1 |
OMAi | VNHTAIN |
OrthoDBi | 792708at2759 |
Miscellaneous databases
BioGRID-ORCSi | 79612, 14 hits in 846 CRISPR screens |
ChiTaRSi | NAA16, human |
GenomeRNAii | 79612 |
Gene expression databases
Bgeei | ENSG00000172766, Expressed in sural nerve and 235 other tissues |
Family and domain databases
InterProi | View protein in InterPro IPR021183, NatA_aux_su IPR013026, TPR-contain_dom IPR011990, TPR-like_helical_dom_sf IPR013105, TPR_2 IPR019734, TPR_repeat |
Pfami | View protein in Pfam PF12569, NARP1, 1 hit PF07719, TPR_2, 1 hit |
PIRSFi | PIRSF000422, N-terminal-AcTrfase-A_aux_su, 1 hit |
SMARTi | View protein in SMART SM00028, TPR, 6 hits |
SUPFAMi | SSF48452, SSF48452, 1 hit |
PROSITEi | View protein in PROSITE PS50005, TPR, 5 hits PS50293, TPR_REGION, 3 hits |
ProtoNeti | Search... |
MobiDBi | Search... |
Entry informationi
Entry namei | A4FU51_HUMAN | |
Accessioni | A4FU51Primary (citable) accession number: A4FU51 | |
Entry historyi | Integrated into UniProtKB/TrEMBL: | April 17, 2007 |
Last sequence update: | April 17, 2007 | |
Last modified: | December 2, 2020 | |
This is version 121 of the entry and version 1 of the sequence. See complete history. | ||
Entry statusi | Unreviewed (UniProtKB/TrEMBL) | |
Disclaimer | Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care. |