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Protein

Protein RecA

Gene

recA

Organism
Saccharopolyspora erythraea (strain ATCC 11635 / DSM 40517 / JCM 4748 / NBRC 13426 / NCIMB 8594 / NRRL 2338)
Status
Reviewed-Annotation score: -Protein inferred from homologyi

Functioni

Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage.UniRule annotation

Regions

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Nucleotide bindingi67 – 74ATPUniRule annotation8

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionDNA-binding
Biological processDNA damage, DNA recombination, DNA repair, SOS response
LigandATP-binding, Nucleotide-binding

Names & Taxonomyi

Protein namesi
Recommended name:
Protein RecAUniRule annotation
Alternative name(s):
Recombinase AUniRule annotation
Gene namesi
Name:recAUniRule annotation
Ordered Locus Names:SACE_1736
OrganismiSaccharopolyspora erythraea (strain ATCC 11635 / DSM 40517 / JCM 4748 / NBRC 13426 / NCIMB 8594 / NRRL 2338)
Taxonomic identifieri405948 [NCBI]
Taxonomic lineageiBacteriaActinobacteriaPseudonocardialesPseudonocardiaceaeSaccharopolyspora
Proteomesi
  • UP000006728 Componenti: Chromosome

Subcellular locationi

GO - Cellular componenti

Keywords - Cellular componenti

Cytoplasm

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_10000479891 – 346Protein RecAAdd BLAST346

Interactioni

Protein-protein interaction databases

STRINGi405948.SeryN2_010100007062

Structurei

3D structure databases

ProteinModelPortaliA4FAH9
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the RecA family.UniRule annotation

Phylogenomic databases

eggNOGiENOG4105C68 Bacteria
COG0468 LUCA
HOGENOMiHOG000264120
KOiK03553
OMAiSKMGLQA
OrthoDBiPOG091H01OP

Family and domain databases

CDDicd00983 recA, 1 hit
Gene3Di3.30.250.10, 1 hit
HAMAPiMF_00268 RecA, 1 hit
InterProiView protein in InterPro
IPR003593 AAA+_ATPase
IPR013765 DNA_recomb/repair_RecA
IPR020584 DNA_recomb/repair_RecA_CS
IPR027417 P-loop_NTPase
IPR020588 RecA_ATP-bd
IPR023400 RecA_C
IPR020587 RecA_monomer-monomer_interface
PANTHERiPTHR22942:SF1 PTHR22942:SF1, 1 hit
PfamiView protein in Pfam
PF00154 RecA, 1 hit
PRINTSiPR00142 RECA
SMARTiView protein in SMART
SM00382 AAA, 1 hit
SUPFAMiSSF52540 SSF52540, 1 hit
SSF54752 SSF54752, 1 hit
TIGRFAMsiTIGR02012 tigrfam_recA, 1 hit
PROSITEiView protein in PROSITE
PS00321 RECA_1, 1 hit
PS50162 RECA_2, 1 hit
PS50163 RECA_3, 1 hit

Sequencei

Sequence statusi: Complete.

A4FAH9-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MAATPDKGKA LELALAQIDK QYGKGSVMRL GDETRAPIEV IPTGSISLDV
60 70 80 90 100
ALGIGGLPRG RIVEVYGPES SGKTSVALHA VANAQKLGGT AAFIDAEHAL
110 120 130 140 150
DPEYAKAIGV DTDSLLVSQP DTGEQALEIA DMLIRSGALD IIVIDSVAAL
160 170 180 190 200
VPRAEIEGEM GDSHVGLQAR LMSQALRKLT SALYNAKTTA IFINQLREKV
210 220 230 240 250
GVMFGSPETT TGGKALKFYS SVRLDVRRIE TLKDGSDAVG NRTRVKVVKN
260 270 280 290 300
KVAPPFKQAE FDIIYGIGIS REGSLIDMGV EQGIIRKSGA WYTYEGDQLG
310 320 330 340
QGKENARKFM RENPDVANEI EKRIKEKLGI GAQVDAETAD PAPVDF
Length:346
Mass (Da):36,964
Last modified:April 17, 2007 - v1
Checksum:i9AE5C456A71DEF76
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AM420293 Genomic DNA Translation: CAM01054.1
RefSeqiWP_009943797.1, NZ_PDBV01000001.1

Genome annotation databases

EnsemblBacteriaiCAM01054; CAM01054; SACE_1736
KEGGisen:SACE_1736

Similar proteinsi

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AM420293 Genomic DNA Translation: CAM01054.1
RefSeqiWP_009943797.1, NZ_PDBV01000001.1

3D structure databases

ProteinModelPortaliA4FAH9
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi405948.SeryN2_010100007062

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiCAM01054; CAM01054; SACE_1736
KEGGisen:SACE_1736

Phylogenomic databases

eggNOGiENOG4105C68 Bacteria
COG0468 LUCA
HOGENOMiHOG000264120
KOiK03553
OMAiSKMGLQA
OrthoDBiPOG091H01OP

Family and domain databases

CDDicd00983 recA, 1 hit
Gene3Di3.30.250.10, 1 hit
HAMAPiMF_00268 RecA, 1 hit
InterProiView protein in InterPro
IPR003593 AAA+_ATPase
IPR013765 DNA_recomb/repair_RecA
IPR020584 DNA_recomb/repair_RecA_CS
IPR027417 P-loop_NTPase
IPR020588 RecA_ATP-bd
IPR023400 RecA_C
IPR020587 RecA_monomer-monomer_interface
PANTHERiPTHR22942:SF1 PTHR22942:SF1, 1 hit
PfamiView protein in Pfam
PF00154 RecA, 1 hit
PRINTSiPR00142 RECA
SMARTiView protein in SMART
SM00382 AAA, 1 hit
SUPFAMiSSF52540 SSF52540, 1 hit
SSF54752 SSF54752, 1 hit
TIGRFAMsiTIGR02012 tigrfam_recA, 1 hit
PROSITEiView protein in PROSITE
PS00321 RECA_1, 1 hit
PS50162 RECA_2, 1 hit
PS50163 RECA_3, 1 hit
ProtoNetiSearch...

Entry informationi

Entry nameiRECA_SACEN
AccessioniPrimary (citable) accession number: A4FAH9
Entry historyiIntegrated into UniProtKB/Swiss-Prot: January 15, 2008
Last sequence update: April 17, 2007
Last modified: October 10, 2018
This is version 76 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families
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Main funding by: National Institutes of Health

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