Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Entry version 97 (13 Feb 2019)
Sequence version 2 (29 Apr 2008)
Previous versions | rss
Other tutorials and videosHelp videoFeedback
Protein

Delphilin

Gene

GRID2IP

Organism
Homo sapiens (Human)
Status
Reviewed-Annotation score:

Annotation score:3 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Protein inferred from homologyi <p>This indicates the type of evidence that supports the existence of the protein. Note that the ‘protein existence’ evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

Postsynaptic scaffolding protein at the parallel fiber-Purkinje cell synapse, where it may serve to link GRID2 with actin cytoskeleton and various signaling molecules.By similarity

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Biological processi

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Recommended name:
Delphilin
Alternative name(s):
Glutamate receptor, ionotropic, delta 2-interacting protein 1
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: ‘Name’, ‘Synonyms’, ‘Ordered locus names’ and ‘ORF names’.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:GRID2IP
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiHomo sapiens (Human)
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the ‘taxonomic identifier’ or ‘taxid’.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri9606 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000005640 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes_manual">proteome</a> can consist of several components. <br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome 7

Organism-specific databases

Eukaryotic Pathogen Database Resources

More...
EuPathDBi
HostDB:ENSG00000215045.8

Human Gene Nomenclature Database

More...
HGNCi
HGNC:18464 GRID2IP

Online Mendelian Inheritance in Man (OMIM)

More...
MIMi
610639 gene

neXtProt; the human protein knowledge platform

More...
neXtProti
NX_A4D2P6

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywords - Cellular componenti

Cell junction, Cell membrane, Membrane, Postsynaptic cell membrane, Synapse

<p>This section provides information on the disease(s) and phenotype(s) associated with a protein.<p><a href='/help/pathology_and_biotech_section' target='_top'>More...</a></p>Pathology & Biotechi

Organism-specific databases

Open Targets

More...
OpenTargetsi
ENSG00000215045

The Pharmacogenetics and Pharmacogenomics Knowledge Base

More...
PharmGKBi
PA134951825

Polymorphism and mutation databases

BioMuta curated single-nucleotide variation and disease association database

More...
BioMutai
GRID2IP

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘PTM / Processing’ section describes the extent of a polypeptide chain in the mature protein following processing.<p><a href='/help/chain' target='_top'>More...</a></p>ChainiPRO_00003316241 – 1211DelphilinAdd BLAST1211

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘PTM / Processing’ section specifies the position and type of each modified residue excluding <a href="http://www.uniprot.org/manual/lipid">lipids</a>, <a href="http://www.uniprot.org/manual/carbohyd">glycans</a> and <a href="http://www.uniprot.org/manual/crosslnk">protein cross-links</a>.<p><a href='/help/mod_res' target='_top'>More...</a></p>Modified residuei580PhosphoserineBy similarity1
Modified residuei621PhosphoserineBy similarity1
Modified residuei652PhosphoserineBy similarity1
Modified residuei655PhosphoserineBy similarity1

Keywords - PTMi

Phosphoprotein

Proteomic databases

jPOST - Japan Proteome Standard Repository/Database

More...
jPOSTi
A4D2P6

PaxDb, a database of protein abundance averages across all three domains of life

More...
PaxDbi
A4D2P6

PRoteomics IDEntifications database

More...
PRIDEi
A4D2P6

ProteomicsDB human proteome resource

More...
ProteomicsDBi
648

PTM databases

iPTMnet integrated resource for PTMs in systems biology context

More...
iPTMneti
A4D2P6

Comprehensive resource for the study of protein post-translational modifications (PTMs) in human, mouse and rat.

More...
PhosphoSitePlusi
A4D2P6

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

Gene expression databases

Bgee dataBase for Gene Expression Evolution

More...
Bgeei
ENSG00000215045 Expressed in 62 organ(s), highest expression level in hypothalamus

ExpressionAtlas, Differential and Baseline Expression

More...
ExpressionAtlasi
A4D2P6 baseline and differential

Organism-specific databases

Human Protein Atlas

More...
HPAi
HPA045381

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

<p>This subsection of the <a href="http://www.uniprot.org/help/interaction_section">'Interaction'</a> section provides information about the protein quaternary structure and interaction(s) with other proteins or protein complexes (with the exception of physiological receptor-ligand interactions which are annotated in the <a href="http://www.uniprot.org/help/function_section">'Function'</a> section).<p><a href='/help/subunit_structure' target='_top'>More...</a></p>Subunit structurei

Interacts with C-terminus of the glutamate receptor GRID2 via PDZ domain.By similarity

Protein-protein interaction databases

The Biological General Repository for Interaction Datasets (BioGrid)

More...
BioGridi
134314, 1 interactor

Database of interacting proteins

More...
DIPi
DIP-59489N

Protein interaction database and analysis system

More...
IntActi
A4D2P6, 1 interactor

STRING: functional protein association networks

More...
STRINGi
9606.ENSP00000397351

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

3D structure databases

Protein Model Portal of the PSI-Nature Structural Biology Knowledgebase

More...
ProteinModelPortali
A4D2P6

SWISS-MODEL Repository - a database of annotated 3D protein structure models

More...
SMRi
A4D2P6

Database of comparative protein structure models

More...
ModBasei
Search...

MobiDB: a database of protein disorder and mobility annotations

More...
MobiDBi
Search...

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/family_and_domains_section">Family and Domains</a> section describes the position and type of a domain, which is defined as a specific combination of secondary structures organized into a characteristic three-dimensional structure or fold.<p><a href='/help/domain' target='_top'>More...</a></p>Domaini3 – 84PDZ 1PROSITE-ProRule annotationAdd BLAST82
Domaini279 – 356PDZ 2PROSITE-ProRule annotationAdd BLAST78
Domaini820 – 1211FH2PROSITE-ProRule annotationAdd BLAST392

Compositional bias

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Family and Domains’ section describes the position of regions of compositional bias within the protein and the particular amino acids that are over-represented within those regions.<p><a href='/help/compbias' target='_top'>More...</a></p>Compositional biasi581 – 662Pro-richAdd BLAST82
Compositional biasi750 – 812Pro-richAdd BLAST63

Keywords - Domaini

Repeat

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

More...
eggNOGi
KOG1922 Eukaryota
KOG3528 Eukaryota
ENOG410XSM6 LUCA

Ensembl GeneTree

More...
GeneTreei
ENSGT00940000157625

The HOGENOM Database of Homologous Genes from Fully Sequenced Organisms

More...
HOGENOMi
HOG000112812

The HOVERGEN Database of Homologous Vertebrate Genes

More...
HOVERGENi
HBG107964

InParanoid: Eukaryotic Ortholog Groups

More...
InParanoidi
A4D2P6

Identification of Orthologs from Complete Genome Data

More...
OMAi
APVWIES

Database of Orthologous Groups

More...
OrthoDBi
790964at2759

Database for complete collections of gene phylogenies

More...
PhylomeDBi
A4D2P6

TreeFam database of animal gene trees

More...
TreeFami
TF329416

Family and domain databases

Integrated resource of protein families, domains and functional sites

More...
InterProi
View protein in InterPro
IPR015425 FH2_Formin
IPR001478 PDZ
IPR036034 PDZ_sf

Pfam protein domain database

More...
Pfami
View protein in Pfam
PF02181 FH2, 1 hit
PF00595 PDZ, 2 hits

Simple Modular Architecture Research Tool; a protein domain database

More...
SMARTi
View protein in SMART
SM00498 FH2, 1 hit
SM00228 PDZ, 2 hits

Superfamily database of structural and functional annotation

More...
SUPFAMi
SSF50156 SSF50156, 2 hits

PROSITE; a protein domain and family database

More...
PROSITEi
View protein in PROSITE
PS51444 FH2, 1 hit
PS50106 PDZ, 2 hits

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence_length">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>.<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequence (1+)i

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences_section">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

This entry has 1 described isoform and 2 potential isoforms that are computationally mapped.Show allAlign All

A4D2P6-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MATTATPATN QGWPEDFGFR LGGSGPCFVL EVAKGSSAHA GGLRPGDQIL
60 70 80 90 100
EVEGLAVGGL SRERLVRLAR RCPRVPPSLG VLPAPDGGPG PGSGPAAPTT
110 120 130 140 150
VLRAPRCGRG LALGRELLRL AGRKRPDAVH RERRRKAQEF SRKVDEILGD
160 170 180 190 200
QPTAKEQVFA ALKQFAAEQR VDDLVWTLTL ALPREACGPL LDNLRIFIPK
210 220 230 240 250
KHRARFDEVV SQGLLGKLCR ARRAQGAQRL RRSRSEERPE RLLVSTRASA
260 270 280 290 300
PPRRPDEPPP RRASLLVGGL AGPGGARRTV RVYKGNKSFG FTLRGHGPVW
310 320 330 340 350
IESVLPGSPA DNAALKSGDR ILFLNGLDMR NCSHDKVVSM LQGSGAMPTL
360 370 380 390 400
VVEEGLVPFA SDSDSLDSPN PSSALTSLQW VAEILPSSIR VQGRTFSQQL
410 420 430 440 450
EHLLTPPERY GVCRALESFF QHRNIDTLIV DVYPVLDTPA KQVLWQFIYQ
460 470 480 490 500
LLTYEEQELC QEKIACFLGY TAMTAEPEPE LDLESEPTPE PQPRSSLRAS
510 520 530 540 550
SMCRRSLRSQ GLEAGLSCGP SECPEMPLPL IPGERQAGDG TSLPETPNPK
560 570 580 590 600
MMSAVYAELE SRLNSSFKGK MGTVSKSRAS PPGPSPAVTT GPRTLSGVSW
610 620 630 640 650
PSERLLPSPC YHPLCSGGLA SPSSSESHPY ASLDSSRAPS PQPGPGPICP
660 670 680 690 700
DSPPSPDPTR PPSRRKLFTF SHPVRSRDTD RFLDVLSEQL GPRVTIVDDF
710 720 730 740 750
LTPENDYEEM SFHDDQGSFV TNERSSASDC ISSSEEGSSL TYSSISDHIP
760 770 780 790 800
PPPLSPPPPP PLPFHDAKPS SRSSDGSRGP AQALAKPLTQ LSHPVPPPPP
810 820 830 840 850
PPLPPPVPCA PPMLSRGLGH RRSETSHMSV KRLRWEQVEN SEGTIWGQLG
860 870 880 890 900
EDSDYDKLSD MVKYLDLELH FGTQKPAKPV PGPEPFRKKE VVEILSHKKA
910 920 930 940 950
YNTSILLAHL KLSPAELRQV LMSMEPRRLE PAHLAQLLLF APDADEEQRY
960 970 980 990 1000
QAFREAPGRL SEPDQFVLQM LSVPEYKTRL RSLHFQATLQ EKTEEIRGSL
1010 1020 1030 1040 1050
ECLRQASLEL KNSRKLAKIL EFVLAMGNYL NDGQPKTNKT TGFKINFLTE
1060 1070 1080 1090 1100
LNSTKTVDGK STFLHILAKS LSQHFPELLG FAQDLPTVPL AAKVNQRALT
1110 1120 1130 1140 1150
SDLADLHGTI SEIQDACQSI SPSSEDKFAM VMSSFLETAQ PALRALDGLQ
1160 1170 1180 1190 1200
REAMEELGKA LAFFGEDSKA TTSEAFFGIF AEFMSKFERA LSDLQAGEGL
1210
RSSGMVSPLA W
Length:1,211
Mass (Da):132,276
Last modified:April 29, 2008 - v2
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:i44D7B5C97461E2E0
GO

<p>In eukaryotic reference proteomes, unreviewed entries that are likely to belong to the same gene are computationally mapped, based on gene identifiers from Ensembl, EnsemblGenomes and model organism databases.<p><a href='/help/gene_centric_isoform_mapping' target='_top'>More...</a></p>Computationally mapped potential isoform sequencesi

There are 2 potential isoforms mapped to this entry.BLASTAlignShow allAdd to basket
EntryEntry nameProtein names
Gene namesLengthAnnotation
C9JNS8C9JNS8_HUMAN
Delphilin
GRID2IP
1,027Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
C9J5F6C9J5F6_HUMAN
Delphilin
GRID2IP
1,020Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>

<p>This subsection of the ‘Sequence’ section reports difference(s) between the protein sequence shown in the UniProtKB entry and other available protein sequences derived from the same gene.<p><a href='/help/sequence_caution' target='_top'>More...</a></p>Sequence cautioni

The sequence EAL23724 differs from that shown. Reason: Erroneous gene model prediction.Curated

Natural variant

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Sequence’ section describes natural variant(s) of the protein sequence.<p><a href='/help/variant' target='_top'>More...</a></p>Natural variantiVAR_04290920R → Q. Corresponds to variant dbSNP:rs11761490Ensembl.1

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...
EMBLi

GenBank nucleotide sequence database

More...
GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...
DDBJi
Links Updated
AC072052 Genomic DNA No translation available.
CH236963 Genomic DNA Translation: EAL23724.1 Sequence problems.

The Consensus CDS (CCDS) project

More...
CCDSi
CCDS47537.1

NCBI Reference Sequences

More...
RefSeqi
NP_001138590.1, NM_001145118.1

UniGene gene-oriented nucleotide sequence clusters

More...
UniGenei
Hs.512174

Genome annotation databases

Ensembl eukaryotic genome annotation project

More...
Ensembli
ENST00000457091; ENSP00000397351; ENSG00000215045

Database of genes from NCBI RefSeq genomes

More...
GeneIDi
392862

KEGG: Kyoto Encyclopedia of Genes and Genomes

More...
KEGGi
hsa:392862

UCSC genome browser

More...
UCSCi
uc011jwx.3 human

Keywords - Coding sequence diversityi

Polymorphism

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC072052 Genomic DNA No translation available.
CH236963 Genomic DNA Translation: EAL23724.1 Sequence problems.
CCDSiCCDS47537.1
RefSeqiNP_001138590.1, NM_001145118.1
UniGeneiHs.512174

3D structure databases

ProteinModelPortaliA4D2P6
SMRiA4D2P6
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

BioGridi134314, 1 interactor
DIPiDIP-59489N
IntActiA4D2P6, 1 interactor
STRINGi9606.ENSP00000397351

PTM databases

iPTMnetiA4D2P6
PhosphoSitePlusiA4D2P6

Polymorphism and mutation databases

BioMutaiGRID2IP

Proteomic databases

jPOSTiA4D2P6
PaxDbiA4D2P6
PRIDEiA4D2P6
ProteomicsDBi648

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENST00000457091; ENSP00000397351; ENSG00000215045
GeneIDi392862
KEGGihsa:392862
UCSCiuc011jwx.3 human

Organism-specific databases

Comparative Toxicogenomics Database

More...
CTDi
392862
EuPathDBiHostDB:ENSG00000215045.8

GeneCards: human genes, protein and diseases

More...
GeneCardsi
GRID2IP
HGNCiHGNC:18464 GRID2IP
HPAiHPA045381
MIMi610639 gene
neXtProtiNX_A4D2P6
OpenTargetsiENSG00000215045
PharmGKBiPA134951825

GenAtlas: human gene database

More...
GenAtlasi
Search...

Phylogenomic databases

eggNOGiKOG1922 Eukaryota
KOG3528 Eukaryota
ENOG410XSM6 LUCA
GeneTreeiENSGT00940000157625
HOGENOMiHOG000112812
HOVERGENiHBG107964
InParanoidiA4D2P6
OMAiAPVWIES
OrthoDBi790964at2759
PhylomeDBiA4D2P6
TreeFamiTF329416

Miscellaneous databases

Database of phenotypes from RNA interference screens in Drosophila and Homo sapiens

More...
GenomeRNAii
392862

Protein Ontology

More...
PROi
PR:A4D2P6

The Stanford Online Universal Resource for Clones and ESTs

More...
SOURCEi
Search...

Gene expression databases

BgeeiENSG00000215045 Expressed in 62 organ(s), highest expression level in hypothalamus
ExpressionAtlasiA4D2P6 baseline and differential

Family and domain databases

InterProiView protein in InterPro
IPR015425 FH2_Formin
IPR001478 PDZ
IPR036034 PDZ_sf
PfamiView protein in Pfam
PF02181 FH2, 1 hit
PF00595 PDZ, 2 hits
SMARTiView protein in SMART
SM00498 FH2, 1 hit
SM00228 PDZ, 2 hits
SUPFAMiSSF50156 SSF50156, 2 hits
PROSITEiView protein in PROSITE
PS51444 FH2, 1 hit
PS50106 PDZ, 2 hits

ProtoNet; Automatic hierarchical classification of proteins

More...
ProtoNeti
Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the ‘Entry information’ section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiGRD2I_HUMAN
<p>This subsection of the ‘Entry information’ section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called ‘Primary (citable) accession number’.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: A4D2P6
<p>This subsection of the ‘Entry information’ section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification (‘Last modified’). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/Swiss-Prot: April 29, 2008
Last sequence update: April 29, 2008
Last modified: February 13, 2019
This is version 97 of the entry and version 2 of the sequence. See complete history.
<p>This subsection of the ‘Entry information’ section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

<p>This section contains any relevant information that doesn’t fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Human chromosome 7
    Human chromosome 7: entries, gene names and cross-references to MIM
  2. MIM cross-references
    Online Mendelian Inheritance in Man (MIM) cross-references in UniProtKB/Swiss-Prot
  3. Human entries with polymorphisms or disease mutations
    List of human entries with polymorphisms or disease mutations
  4. Human polymorphisms and disease mutations
    Index of human polymorphisms and disease mutations
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health

We'd like to inform you that we have updated our Privacy Notice to comply with Europe’s new General Data Protection Regulation (GDPR) that applies since 25 May 2018.

Do not show this banner again