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Entry version 90 (08 May 2019)
Sequence version 1 (03 Apr 2007)
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Protein

Protein FAM221A

Gene

FAM221A

Organism
Homo sapiens (Human)
Status
Reviewed-Annotation score:

Annotation score:3 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Experimental evidence at protein leveli <p>This indicates the type of evidence that supports the existence of the protein. Note that the ‘protein existence’ evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Recommended name:
Protein FAM221A
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: ‘Name’, ‘Synonyms’, ‘Ordered locus names’ and ‘ORF names’.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:FAM221A
Synonyms:C7orf46
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiHomo sapiens (Human)
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the ‘taxonomic identifier’ or ‘taxid’.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri9606 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000005640 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes_manual">proteome</a> can consist of several components. <br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome 7

Organism-specific databases

Human Gene Nomenclature Database

More...
HGNCi
HGNC:27977 FAM221A

neXtProt; the human protein knowledge platform

More...
neXtProti
NX_A4D161

<p>This section provides information on the disease(s) and phenotype(s) associated with a protein.<p><a href='/help/pathology_and_biotech_section' target='_top'>More...</a></p>Pathology & Biotechi

Organism-specific databases

Open Targets

More...
OpenTargetsi
ENSG00000188732

The Pharmacogenetics and Pharmacogenomics Knowledge Base

More...
PharmGKBi
PA162380501

Polymorphism and mutation databases

BioMuta curated single-nucleotide variation and disease association database

More...
BioMutai
FAM221A

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘PTM / Processing’ section describes the extent of a polypeptide chain in the mature protein following processing.<p><a href='/help/chain' target='_top'>More...</a></p>ChainiPRO_00002951391 – 298Protein FAM221AAdd BLAST298

Proteomic databases

Encyclopedia of Proteome Dynamics

More...
EPDi
A4D161

jPOST - Japan Proteome Standard Repository/Database

More...
jPOSTi
A4D161

MaxQB - The MaxQuant DataBase

More...
MaxQBi
A4D161

PaxDb, a database of protein abundance averages across all three domains of life

More...
PaxDbi
A4D161

PRoteomics IDEntifications database

More...
PRIDEi
A4D161

ProteomicsDB human proteome resource

More...
ProteomicsDBi
604
605 [A4D161-2]
606 [A4D161-3]

Consortium for Top Down Proteomics

More...
TopDownProteomicsi
A4D161-1 [A4D161-1]

PTM databases

iPTMnet integrated resource for PTMs in systems biology context

More...
iPTMneti
A4D161

Comprehensive resource for the study of protein post-translational modifications (PTMs) in human, mouse and rat.

More...
PhosphoSitePlusi
A4D161

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

Gene expression databases

Bgee dataBase for Gene Expression Evolution

More...
Bgeei
ENSG00000188732 Expressed in 181 organ(s), highest expression level in pigmented layer of retina

ExpressionAtlas, Differential and Baseline Expression

More...
ExpressionAtlasi
A4D161 baseline and differential

Genevisible search portal to normalized and curated expression data from Genevestigator

More...
Genevisiblei
A4D161 HS

Organism-specific databases

Human Protein Atlas

More...
HPAi
HPA019719
HPA026748
HPA026752

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

<p>This subsection of the '<a href="http://www.uniprot.org/help/interaction_section%27">Interaction</a> section provides information about binary protein-protein interactions. The data presented in this section are a quality-filtered subset of binary interactions automatically derived from the <a href="http://www.ebi.ac.uk/intact/">IntAct database</a>. It is updated on a monthly basis. Each binary interaction is displayed on a separate line.<p><a href='/help/binary_interactions' target='_top'>More...</a></p>Binary interactionsi

WithEntry#Exp.IntActNotes
HOXA1P496394EBI-11960181,EBI-740785

Protein-protein interaction databases

The Biological General Repository for Interaction Datasets (BioGrid)

More...
BioGridi
131030, 4 interactors

Protein interaction database and analysis system

More...
IntActi
A4D161, 16 interactors

STRING: functional protein association networks

More...
STRINGi
9606.ENSP00000342576

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

<p>This subsection of the ‘Family and domains’ section provides information about the sequence similarity with other proteins.<p><a href='/help/sequence_similarities' target='_top'>More...</a></p>Sequence similaritiesi

Belongs to the FAM221 family.Curated

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

More...
eggNOGi
ENOG410IDX8 Eukaryota
ENOG410XQZY LUCA

Ensembl GeneTree

More...
GeneTreei
ENSGT00770000120611

The HOGENOM Database of Homologous Genes from Fully Sequenced Organisms

More...
HOGENOMi
HOG000007173

InParanoid: Eukaryotic Ortholog Groups

More...
InParanoidi
A4D161

Identification of Orthologs from Complete Genome Data

More...
OMAi
RVTGCQC

Database of Orthologous Groups

More...
OrthoDBi
973186at2759

Database for complete collections of gene phylogenies

More...
PhylomeDBi
A4D161

TreeFam database of animal gene trees

More...
TreeFami
TF329392

Family and domain databases

Integrated resource of protein families, domains and functional sites

More...
InterProi
View protein in InterPro
IPR026755 Fam221a/b

The PANTHER Classification System

More...
PANTHERi
PTHR31214 PTHR31214, 1 hit

Pfam protein domain database

More...
Pfami
View protein in Pfam
PF14753 FAM221, 1 hit

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence_length">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>.<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequences (3+)i

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences_section">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

This entry describes 3 <p>This subsection of the ‘Sequence’ section lists the alternative protein sequences (isoforms) that can be generated from the same gene by a single or by the combination of up to four biological events (alternative promoter usage, alternative splicing, alternative initiation and ribosomal frameshifting). Additionally, this section gives relevant information on each alternative protein isoform.<p><a href='/help/alternative_products' target='_top'>More...</a></p> isoformsi produced by alternative splicing. AlignAdd to basket

This entry has 3 described isoforms and 3 potential isoforms that are computationally mapped.Show allAlign All

Isoform 1 (identifier: A4D161-1) [UniParc]FASTAAdd to basket

This isoform has been chosen as the 'canonical' sequence. All positional information in this entry refers to it. This is also the sequence that appears in the downloadable versions of the entry.

« Hide
        10         20         30         40         50
MERLTLPLGG AAAVDEYLEY RRIVGEDDGG KLFTPEEYEE YKRKVLPLRL
60 70 80 90 100
QNRLFVSWRS PTGMDCKLVG PETLCFCTHR YKQHKTDLEA IPQQCPIDLP
110 120 130 140 150
CQVTGCQCRA YLYVPLNGSQ PIRCRCKHFA DQHSAAPGFT CNTCSKCSGF
160 170 180 190 200
HSCFTCACGQ PAYAHDTVVE TKQERLAQEK PVGQDIPYAA MGGLTGFSSL
210 220 230 240 250
AEGYMRLDDS GIGVPSVEFL ESPITAVDSP FLKAFQASSS SSPETLTDVG
260 270 280 290
TSSQVSSLRR PEEDDMAFFE RRYQERMKME KAAKWKGKAP LPSATKPS
Length:298
Mass (Da):33,083
Last modified:April 3, 2007 - v1
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:iED00395F79B78288
GO
Isoform 2 (identifier: A4D161-2) [UniParc]FASTAAdd to basket

The sequence of this isoform differs from the canonical sequence as follows:
     213-248: Missing.

Show »
Length:262
Mass (Da):29,359
Checksum:iF691A7A6893D8B59
GO
Isoform 3 (identifier: A4D161-3) [UniParc]FASTAAdd to basket

The sequence of this isoform differs from the canonical sequence as follows:
     23-80: Missing.
     213-248: Missing.

Show »
Length:204
Mass (Da):22,617
Checksum:iC13F02A817A423B2
GO

<p>In eukaryotic reference proteomes, unreviewed entries that are likely to belong to the same gene are computationally mapped, based on gene identifiers from Ensembl, EnsemblGenomes and model organism databases.<p><a href='/help/gene_centric_isoform_mapping' target='_top'>More...</a></p>Computationally mapped potential isoform sequencesi

There are 3 potential isoforms mapped to this entry.BLASTAlignShow allAdd to basket
EntryEntry nameProtein names
Gene namesLengthAnnotation
B8ZZQ8B8ZZQ8_HUMAN
Protein FAM221A
FAM221A MGC72075, hCG_37984
240Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
F8WCP3F8WCP3_HUMAN
Protein FAM221A
FAM221A
114Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
F8WCP2F8WCP2_HUMAN
Protein FAM221A
FAM221A
98Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>

<p>This subsection of the ‘Sequence’ section reports difference(s) between the protein sequence shown in the UniProtKB entry and other available protein sequences derived from the same gene.<p><a href='/help/sequence_caution' target='_top'>More...</a></p>Sequence cautioni

The sequence AAH26000 differs from that shown. Reason: Frameshift at position 9.Curated
The sequence AAH42034 differs from that shown. Reason: Frameshift at position 101.Curated

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Sequence’ section reports difference(s) between the canonical sequence (displayed by default in the entry) and the different sequence submissions merged in the entry. These various submissions may originate from different sequencing projects, different types of experiments, or different biological samples. Sequence conflicts are usually of unknown origin.<p><a href='/help/conflict' target='_top'>More...</a></p>Sequence conflicti101C → R in AAH42034 (PubMed:15489334).Curated1

Natural variant

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Sequence’ section describes natural variant(s) of the protein sequence.<p><a href='/help/variant' target='_top'>More...</a></p>Natural variantiVAR_03321520Y → H1 PublicationCorresponds to variant dbSNP:rs17855785Ensembl.1
Natural variantiVAR_03321690A → T. Corresponds to variant dbSNP:rs34518648Ensembl.1
Natural variantiVAR_03321795C → R. Corresponds to variant dbSNP:rs35495590Ensembl.1
Natural variantiVAR_033218128H → R1 PublicationCorresponds to variant dbSNP:rs17855786Ensembl.1
Natural variantiVAR_033219240S → G. Corresponds to variant dbSNP:rs35928055Ensembl.1

Alternative sequence

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Sequence’ section describes the sequence of naturally occurring alternative protein isoform(s). The changes in the amino acid sequence may be due to alternative splicing, alternative promoter usage, alternative initiation, or ribosomal frameshifting.<p><a href='/help/var_seq' target='_top'>More...</a></p>Alternative sequenceiVSP_02673823 – 80Missing in isoform 3. 1 PublicationAdd BLAST58
Alternative sequenceiVSP_026739213 – 248Missing in isoform 2 and isoform 3. 1 PublicationAdd BLAST36

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...
EMBLi

GenBank nucleotide sequence database

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GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...
DDBJi
Links Updated
CH236948 Genomic DNA Translation: EAL24251.1
BC026000 mRNA Translation: AAH26000.1 Frameshift.
BC042034 mRNA Translation: AAH42034.1 Frameshift.
BC063130 mRNA Translation: AAH63130.1

The Consensus CDS (CCDS) project

More...
CCDSi
CCDS47561.1 [A4D161-2]
CCDS47562.1 [A4D161-3]
CCDS5385.1 [A4D161-1]

NCBI Reference Sequences

More...
RefSeqi
NP_001120836.1, NM_001127364.2 [A4D161-2]
NP_001120837.1, NM_001127365.2 [A4D161-3]
NP_001287861.1, NM_001300932.1
NP_954587.2, NM_199136.4 [A4D161-1]
XP_011513671.1, XM_011515369.2 [A4D161-1]

Genome annotation databases

Ensembl eukaryotic genome annotation project

More...
Ensembli
ENST00000344962; ENSP00000342576; ENSG00000188732 [A4D161-1]
ENST00000409192; ENSP00000386927; ENSG00000188732 [A4D161-2]
ENST00000409994; ENSP00000386631; ENSG00000188732 [A4D161-3]

Database of genes from NCBI RefSeq genomes

More...
GeneIDi
340277

KEGG: Kyoto Encyclopedia of Genes and Genomes

More...
KEGGi
hsa:340277

UCSC genome browser

More...
UCSCi
uc003swo.4 human [A4D161-1]

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywords - Coding sequence diversityi

Alternative splicing, Polymorphism

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CH236948 Genomic DNA Translation: EAL24251.1
BC026000 mRNA Translation: AAH26000.1 Frameshift.
BC042034 mRNA Translation: AAH42034.1 Frameshift.
BC063130 mRNA Translation: AAH63130.1
CCDSiCCDS47561.1 [A4D161-2]
CCDS47562.1 [A4D161-3]
CCDS5385.1 [A4D161-1]
RefSeqiNP_001120836.1, NM_001127364.2 [A4D161-2]
NP_001120837.1, NM_001127365.2 [A4D161-3]
NP_001287861.1, NM_001300932.1
NP_954587.2, NM_199136.4 [A4D161-1]
XP_011513671.1, XM_011515369.2 [A4D161-1]

3D structure databases

Database of comparative protein structure models

More...
ModBasei
Search...

MobiDB: a database of protein disorder and mobility annotations

More...
MobiDBi
Search...

SWISS-MODEL Interactive Workspace

More...
SWISS-MODEL-Workspacei
Submit a new modelling project...

Protein-protein interaction databases

BioGridi131030, 4 interactors
IntActiA4D161, 16 interactors
STRINGi9606.ENSP00000342576

PTM databases

iPTMnetiA4D161
PhosphoSitePlusiA4D161

Polymorphism and mutation databases

BioMutaiFAM221A

Proteomic databases

EPDiA4D161
jPOSTiA4D161
MaxQBiA4D161
PaxDbiA4D161
PRIDEiA4D161
ProteomicsDBi604
605 [A4D161-2]
606 [A4D161-3]
TopDownProteomicsiA4D161-1 [A4D161-1]

Protocols and materials databases

The DNASU plasmid repository

More...
DNASUi
340277
Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENST00000344962; ENSP00000342576; ENSG00000188732 [A4D161-1]
ENST00000409192; ENSP00000386927; ENSG00000188732 [A4D161-2]
ENST00000409994; ENSP00000386631; ENSG00000188732 [A4D161-3]
GeneIDi340277
KEGGihsa:340277
UCSCiuc003swo.4 human [A4D161-1]

Organism-specific databases

Comparative Toxicogenomics Database

More...
CTDi
340277

GeneCards: human genes, protein and diseases

More...
GeneCardsi
FAM221A
HGNCiHGNC:27977 FAM221A
HPAiHPA019719
HPA026748
HPA026752
neXtProtiNX_A4D161
OpenTargetsiENSG00000188732
PharmGKBiPA162380501

GenAtlas: human gene database

More...
GenAtlasi
Search...

Phylogenomic databases

eggNOGiENOG410IDX8 Eukaryota
ENOG410XQZY LUCA
GeneTreeiENSGT00770000120611
HOGENOMiHOG000007173
InParanoidiA4D161
OMAiRVTGCQC
OrthoDBi973186at2759
PhylomeDBiA4D161
TreeFamiTF329392

Miscellaneous databases

Database of phenotypes from RNA interference screens in Drosophila and Homo sapiens

More...
GenomeRNAii
340277

Protein Ontology

More...
PROi
PR:A4D161

Gene expression databases

BgeeiENSG00000188732 Expressed in 181 organ(s), highest expression level in pigmented layer of retina
ExpressionAtlasiA4D161 baseline and differential
GenevisibleiA4D161 HS

Family and domain databases

InterProiView protein in InterPro
IPR026755 Fam221a/b
PANTHERiPTHR31214 PTHR31214, 1 hit
PfamiView protein in Pfam
PF14753 FAM221, 1 hit

ProtoNet; Automatic hierarchical classification of proteins

More...
ProtoNeti
Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the ‘Entry information’ section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiF221A_HUMAN
<p>This subsection of the ‘Entry information’ section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called ‘Primary (citable) accession number’.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: A4D161
Secondary accession number(s): Q05CG4, Q4G0Q7, Q6P519
<p>This subsection of the ‘Entry information’ section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification (‘Last modified’). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/Swiss-Prot: July 10, 2007
Last sequence update: April 3, 2007
Last modified: May 8, 2019
This is version 90 of the entry and version 1 of the sequence. See complete history.
<p>This subsection of the ‘Entry information’ section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

<p>This section contains any relevant information that doesn’t fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Human chromosome 7
    Human chromosome 7: entries, gene names and cross-references to MIM
  2. SIMILARITY comments
    Index of protein domains and families
  3. Human entries with polymorphisms or disease mutations
    List of human entries with polymorphisms or disease mutations
  4. Human polymorphisms and disease mutations
    Index of human polymorphisms and disease mutations
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