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Protein

UDP-N-acetylglucosamine--N-acetylmuramyl-(pentapeptide) pyrophosphoryl-undecaprenol N-acetylglucosamine transferase

Gene

murG

Organism
Nitrobacter sp. Nb-311A
Status
Unreviewed-Annotation score: -Protein inferred from homologyi

Functioni

Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc-(pentapeptide)GlcNAc (lipid intermediate II).UniRule annotationSAAS annotation

Caution

The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.Imported

Catalytic activityi

UDP-N-acetylglucosamine + Mur2Ac(oyl-L-Ala-gamma-D-Glu-L-Lys-D-Ala-D-Ala)-diphosphoundecaprenol = UDP + GlcNAc-(1->4)-Mur2Ac(oyl-L-Ala-gamma-D-Glu-L-Lys-D-Ala-D-Ala)-diphosphoundecaprenol.UniRule annotationSAAS annotation

Pathwayi: peptidoglycan biosynthesis

This protein is involved in the pathway peptidoglycan biosynthesis, which is part of Cell wall biogenesis.UniRule annotationSAAS annotation
View all proteins of this organism that are known to be involved in the pathway peptidoglycan biosynthesis and in Cell wall biogenesis.

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionGlycosyltransferaseUniRule annotationSAAS annotationImported, Transferase
Biological processCell cycle, Cell divisionUniRule annotationSAAS annotation, Cell shape, Cell wall biogenesis/degradationUniRule annotationSAAS annotation, Peptidoglycan synthesisUniRule annotationSAAS annotation

Enzyme and pathway databases

UniPathwayiUPA00219

Names & Taxonomyi

Protein namesi
Recommended name:
UDP-N-acetylglucosamine--N-acetylmuramyl-(pentapeptide) pyrophosphoryl-undecaprenol N-acetylglucosamine transferaseUniRule annotationSAAS annotation (EC:2.4.1.227UniRule annotationSAAS annotation)
Alternative name(s):
Undecaprenyl-PP-MurNAc-pentapeptide-UDPGlcNAc GlcNAc transferaseUniRule annotation
Gene namesi
Name:murGUniRule annotationImported
ORF Names:NB311A_11407Imported
OrganismiNitrobacter sp. Nb-311AImported
Taxonomic identifieri314253 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaAlphaproteobacteriaRhizobialesBradyrhizobiaceaeNitrobacter
Proteomesi
  • UP000003725 Componenti: Unassembled WGS sequence

Subcellular locationi

  • Cell membrane UniRule annotation; Peripheral membrane protein UniRule annotation

GO - Cellular componenti

Keywords - Cellular componenti

Cell membraneUniRule annotationSAAS annotation, Membrane

Interactioni

Protein-protein interaction databases

STRINGi314253.NB311A_11407

Structurei

3D structure databases

ProteinModelPortaliA3WVE6
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini7 – 143Glyco_transf_28InterPro annotationAdd BLAST137
Domaini190 – 355Glyco_tran_28_CInterPro annotationAdd BLAST166

Sequence similaritiesi

Belongs to the glycosyltransferase 28 family. MurG subfamily.UniRule annotationSAAS annotation

Phylogenomic databases

eggNOGiENOG4105DVQ Bacteria
COG0707 LUCA
OrthoDBiPOG091H02FX

Family and domain databases

CDDicd03785 GT1_MurG, 1 hit
HAMAPiMF_00033 MurG, 1 hit
InterProiView protein in InterPro
IPR006009 GlcNAc_MurG
IPR007235 Glyco_trans_28_C
IPR004276 GlycoTrans_28_N
PfamiView protein in Pfam
PF04101 Glyco_tran_28_C, 1 hit
PF03033 Glyco_transf_28, 1 hit

Sequencei

Sequence statusi: Complete.

A3WVE6-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MATAPLILLA AGGTGGHLFP AEALGVELMK RGLRVRLVTD SRALRYSGLF
60 70 80 90 100
SKDMTDVVPS ETVRGRSPWA LARTGLMLAA GTAVALNLMR VLKPAAVVGF
110 120 130 140 150
GGYPTVPPLI AAQLTGIPTV IHDSNAVMGR ANSFLSKRVS AIATSLPGVL
160 170 180 190 200
DKETSLTGKT MTTGTPMRPA ILAAAAVPFA APSVYGPLRV LVVGGSQGAR
210 220 230 240 250
VMSDVVPVAI ERLEPALRQR LILTQQVRDE DMARVREIYD RLEIEAELAS
260 270 280 290 300
FFADLPARLA SNHIVVSRSG AGTVAELGAI GRPSVLVPLP GAIDQDQFAN
310 320 330 340 350
AGVLADAGGA IRIVQPDFTP DRLAAELSAL AAAPARLATM AAAARTVGRL
360
DAAERLADLV MRVARTGA
Length:368
Mass (Da):38,241
Last modified:April 3, 2007 - v1
Checksum:i6830B6A3F455EEB3
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AAMY01000006 Genomic DNA Translation: EAQ36045.1
RefSeqiWP_009799261.1, NZ_CH672418.1

Genome annotation databases

EnsemblBacteriaiEAQ36045; EAQ36045; NB311A_11407

Similar proteinsi

Entry informationi

Entry nameiA3WVE6_9BRAD
AccessioniPrimary (citable) accession number: A3WVE6
Entry historyiIntegrated into UniProtKB/TrEMBL: April 3, 2007
Last sequence update: April 3, 2007
Last modified: June 20, 2018
This is version 54 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported

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