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Protein

UvrABC system protein C

Gene

uvrC

Organism
Shewanella loihica (strain ATCC BAA-1088 / PV-4)
Status
Reviewed-Annotation score: -Protein inferred from homologyi

Functioni

The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision.UniRule annotation

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionExcision nuclease
Biological processDNA damage, DNA excision, DNA repair, SOS response

Enzyme and pathway databases

BioCyciSLOI323850:G1G8D-1926-MONOMER

Names & Taxonomyi

Protein namesi
Recommended name:
UvrABC system protein CUniRule annotation
Short name:
Protein UvrCUniRule annotation
Alternative name(s):
Excinuclease ABC subunit CUniRule annotation
Gene namesi
Name:uvrCUniRule annotation
Ordered Locus Names:Shew_1825
OrganismiShewanella loihica (strain ATCC BAA-1088 / PV-4)
Taxonomic identifieri323850 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaAlteromonadalesShewanellaceaeShewanella
Proteomesi
  • UP000001558 Componenti: Chromosome

Subcellular locationi

  • Cytoplasm UniRule annotation

GO - Cellular componenti

Keywords - Cellular componenti

Cytoplasm

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_10000778381 – 609UvrABC system protein CAdd BLAST609

Proteomic databases

PRIDEiA3QDZ3

Interactioni

Subunit structurei

Interacts with UvrB in an incision complex.UniRule annotation

Protein-protein interaction databases

STRINGi323850.Shew_1825

Structurei

3D structure databases

ProteinModelPortaliA3QDZ3
SMRiA3QDZ3
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini16 – 94GIY-YIGUniRule annotationAdd BLAST79
Domaini203 – 238UVRUniRule annotationAdd BLAST36

Sequence similaritiesi

Belongs to the UvrC family.UniRule annotation

Phylogenomic databases

eggNOGiENOG4105CII Bacteria
COG0322 LUCA
HOGENOMiHOG000279961
KOiK03703
OMAiLFPIRQC
OrthoDBiPOG091H01BS

Family and domain databases

Gene3Di3.30.420.340, 1 hit
3.40.1440.10, 1 hit
HAMAPiMF_00203 UvrC, 1 hit
InterProiView protein in InterPro
IPR000305 GIY-YIG_endonuc
IPR035901 GIY-YIG_endonuc_sf
IPR003583 Hlx-hairpin-Hlx_DNA-bd_motif
IPR010994 RuvA_2-like
IPR001943 UVR_dom
IPR036876 UVR_dom_sf
IPR004791 UvrC
IPR001162 UvrC_homol_region
IPR038476 UvrC_homol_region_sf
PfamiView protein in Pfam
PF01541 GIY-YIG, 1 hit
PF02151 UVR, 1 hit
PF08459 UvrC_HhH_N, 1 hit
SMARTiView protein in SMART
SM00465 GIYc, 1 hit
SM00278 HhH1, 2 hits
SUPFAMiSSF46600 SSF46600, 1 hit
SSF47781 SSF47781, 1 hit
SSF82771 SSF82771, 1 hit
TIGRFAMsiTIGR00194 uvrC, 1 hit
PROSITEiView protein in PROSITE
PS50164 GIY_YIG, 1 hit
PS50151 UVR, 1 hit
PS50165 UVRC, 1 hit

Sequencei

Sequence statusi: Complete.

A3QDZ3-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MTDSFNATQF LKTVSSSAGV YRMYDAQGVV IYVGKAKDLK KRLSSYFRRN
60 70 80 90 100
LPNVKTQALV SHIANIDVTL TPSETDALIL ENDYIKQYMP RYNVLLRDDK
110 120 130 140 150
SYPYIFLSGH RHPRLAYHRG PQREKGHYFG PYPNGGAVRE SLHLMQKLFP
160 170 180 190 200
IRQCDDLYYK ARSRPCLQYQ IARCSAPCVG KISDEDYAEQ VKLASLFLRG
210 220 230 240 250
KDQQVIATLV GKMEQAAMDL NYEDAARYRD QISALRRVAE QQEVSSDSGD
260 270 280 290 300
MDVIGAYYAS GIACFHLLFI RNGKIFGSRS YYPSVPDETE VSEVLRAFML
310 320 330 340 350
QFYLNVDSQR TLPREIVVSH EFEDIHELEE AIAQASNRRL LIKTKVRSER
360 370 380 390 400
ASFLRIADAN AKNAVETRLS HQNTVEERFL LLEEALEQSQ AINRMECFDI
410 420 430 440 450
SHTMGESTVA SCVVFNREGP SKGEYRRYNI SGITPGDDYA AMKQAIGRRF
460 470 480 490 500
DKIEADGKIP DILFIDGGMG QLRIAQKVVN EKFAHLDVAP TLIGVAKGEG
510 520 530 540 550
RKPGLETLIY GENEVAFSLP ADSGALHLIQ HIRDESHRFA ITGHRNKRQK
560 570 580 590 600
TRNTSTLESI PGVGPKRRKA LLQYLGGLQQ VKGASVAQLS KVPGISLEMA

QTIHDALRG
Length:609
Mass (Da):68,543
Last modified:April 17, 2007 - v1
Checksum:i55BC2D39DDF7C3CF
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP000606 Genomic DNA Translation: ABO23691.1
RefSeqiWP_011865623.1, NC_009092.1

Genome annotation databases

EnsemblBacteriaiABO23691; ABO23691; Shew_1825
KEGGislo:Shew_1825

Similar proteinsi

Entry informationi

Entry nameiUVRC_SHELP
AccessioniPrimary (citable) accession number: A3QDZ3
Entry historyiIntegrated into UniProtKB/Swiss-Prot: May 20, 2008
Last sequence update: April 17, 2007
Last modified: July 18, 2018
This is version 77 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families

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