Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Protein

Ribonuclease P protein component

Gene

rnpA

Organism
Prochlorococcus marinus (strain MIT 9301)
Status
Reviewed-Annotation score: -Protein inferred from homologyi

Functioni

RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme.UniRule annotation

Catalytic activityi

Endonucleolytic cleavage of RNA, removing 5'-extranucleotides from tRNA precursor.UniRule annotation

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionEndonuclease, Hydrolase, Nuclease, RNA-binding
Biological processtRNA processing

Enzyme and pathway databases

BioCyciPMAR167546:G1G8B-1323-MONOMER

Names & Taxonomyi

Protein namesi
Recommended name:
Ribonuclease P protein componentUniRule annotation (EC:3.1.26.5UniRule annotation)
Short name:
RNase P proteinUniRule annotation
Short name:
RNaseP proteinUniRule annotation
Alternative name(s):
Protein C5UniRule annotation
Gene namesi
Name:rnpAUniRule annotation
Ordered Locus Names:P9301_13851
OrganismiProchlorococcus marinus (strain MIT 9301)
Taxonomic identifieri167546 [NCBI]
Taxonomic lineageiBacteriaCyanobacteriaSynechococcalesProchloraceaeProchlorococcus
Proteomesi
  • UP000001430 Componenti: Chromosome

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_10001946591 – 128Ribonuclease P protein componentAdd BLAST128

Proteomic databases

PRIDEiA3PE33

Interactioni

Subunit structurei

Consists of a catalytic RNA component (M1 or rnpB) and a protein subunit.UniRule annotation

Protein-protein interaction databases

STRINGi167546.P9301_13851

Structurei

3D structure databases

ProteinModelPortaliA3PE33
SMRiA3PE33
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the RnpA family.UniRule annotation

Phylogenomic databases

eggNOGiENOG4105UVI Bacteria
ENOG410YT7G LUCA
HOGENOMiHOG000266301
KOiK03536
OMAiMRLKGHR
OrthoDBiPOG091H2QD5

Family and domain databases

Gene3Di3.30.230.10, 1 hit
HAMAPiMF_00227 RNase_P, 1 hit
InterProiView protein in InterPro
IPR020568 Ribosomal_S5_D2-typ_fold
IPR014721 Ribosomal_S5_D2-typ_fold_subgr
IPR000100 RNase_P
PANTHERiPTHR33992 PTHR33992, 1 hit
PfamiView protein in Pfam
PF00825 Ribonuclease_P, 1 hit
SUPFAMiSSF54211 SSF54211, 1 hit
TIGRFAMsiTIGR00188 rnpA, 1 hit

Sequencei

Sequence statusi: Complete.

A3PE33-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MALPKDMRLK GHRTFNYIHK NSITYHGKLM TFKVARSNPG ILLTHKLKNT
60 70 80 90 100
SNKFRVAIAI SKKVSKKAVE RNKLRRILQE WLLTNIQKIN NHKPYWLLVN
110 120
LKFGDFCNDK SKLLEEFQNL MFKSRLIK
Length:128
Mass (Da):15,181
Last modified:April 3, 2007 - v1
Checksum:i51723902DCAEBF81
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP000576 Genomic DNA Translation: ABO18008.1
RefSeqiWP_011863317.1, NC_009091.1

Genome annotation databases

EnsemblBacteriaiABO18008; ABO18008; P9301_13851
GeneIDi4912302
KEGGipmg:P9301_13851

Similar proteinsi

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP000576 Genomic DNA Translation: ABO18008.1
RefSeqiWP_011863317.1, NC_009091.1

3D structure databases

ProteinModelPortaliA3PE33
SMRiA3PE33
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi167546.P9301_13851

Proteomic databases

PRIDEiA3PE33

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiABO18008; ABO18008; P9301_13851
GeneIDi4912302
KEGGipmg:P9301_13851

Phylogenomic databases

eggNOGiENOG4105UVI Bacteria
ENOG410YT7G LUCA
HOGENOMiHOG000266301
KOiK03536
OMAiMRLKGHR
OrthoDBiPOG091H2QD5

Enzyme and pathway databases

BioCyciPMAR167546:G1G8B-1323-MONOMER

Family and domain databases

Gene3Di3.30.230.10, 1 hit
HAMAPiMF_00227 RNase_P, 1 hit
InterProiView protein in InterPro
IPR020568 Ribosomal_S5_D2-typ_fold
IPR014721 Ribosomal_S5_D2-typ_fold_subgr
IPR000100 RNase_P
PANTHERiPTHR33992 PTHR33992, 1 hit
PfamiView protein in Pfam
PF00825 Ribonuclease_P, 1 hit
SUPFAMiSSF54211 SSF54211, 1 hit
TIGRFAMsiTIGR00188 rnpA, 1 hit
ProtoNetiSearch...

Entry informationi

Entry nameiRNPA_PROM0
AccessioniPrimary (citable) accession number: A3PE33
Entry historyiIntegrated into UniProtKB/Swiss-Prot: July 28, 2009
Last sequence update: April 3, 2007
Last modified: October 10, 2018
This is version 63 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health

We'd like to inform you that we have updated our Privacy Notice to comply with Europe’s new General Data Protection Regulation (GDPR) that applies since 25 May 2018.

Do not show this banner again