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UniProtKB - A3LZ43 (A3LZ43_PICST)

Entry version 54 (07 Oct 2020)
Sequence version 2 (24 Jul 2007)
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Protein
Submitted name:

Uncharacterized protein

Gene

PICST_63741

Organism
Scheffersomyces stipitis (strain ATCC 58785 / CBS 6054 / NBRC 10063 / NRRL Y-11545) (Yeast) (Pichia stipitis)
Status
Unreviewed-Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>-Protein inferred from homologyi <p>This indicates the type of evidence that supports the existence of the protein. Note that the 'protein existence' evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Biological processi

Complete GO annotation on QuickGO ...

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywordsi

Biological processPeptide transportARBA annotation, Protein transport, Transport

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Submitted name:
Uncharacterized proteinImported
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: 'Name', 'Synonyms', 'Ordered locus names' and 'ORF names'.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
ORF Names:PICST_63741Imported
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiScheffersomyces stipitis (strain ATCC 58785 / CBS 6054 / NBRC 10063 / NRRL Y-11545) (Yeast) (Pichia stipitis)Imported
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the 'taxonomic identifier' or 'taxid'.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri322104 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryota › Fungi › Dikarya › Ascomycota › Saccharomycotina › Saccharomycetes › Saccharomycetales › Debaryomycetaceae › Scheffersomyces ›
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000002258 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes%5Fmanual">proteome</a> can consist of several components.<br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome 7

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/subcellular%5Flocation%5Fsection">'Subcellular location'</a> section describes the extent of a membrane-spanning region of the protein. It denotes the presence of both alpha-helical transmembrane regions and the membrane spanning regions of beta-barrel transmembrane proteins.<p><a href='/help/transmem' target='_top'>More...</a></p>Transmembranei232 – 254HelicalSequence analysisAdd BLAST23
Transmembranei279 – 299HelicalSequence analysisAdd BLAST21
Transmembranei320 – 340HelicalSequence analysisAdd BLAST21
Transmembranei346 – 363HelicalSequence analysisAdd BLAST18
Transmembranei375 – 394HelicalSequence analysisAdd BLAST20
Transmembranei414 – 434HelicalSequence analysisAdd BLAST21
Transmembranei455 – 473HelicalSequence analysisAdd BLAST19
Transmembranei527 – 546HelicalSequence analysisAdd BLAST20
Transmembranei591 – 611HelicalSequence analysisAdd BLAST21
Transmembranei617 – 638HelicalSequence analysisAdd BLAST22
Transmembranei699 – 723HelicalSequence analysisAdd BLAST25
Transmembranei768 – 786HelicalSequence analysisAdd BLAST19
Transmembranei807 – 832HelicalSequence analysisAdd BLAST26
Transmembranei844 – 866HelicalSequence analysisAdd BLAST23

Keywords - Cellular componenti

Membrane

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

<p>This subsection of the 'Family and domains' section provides information about the sequence similarity with other proteins.<p><a href='/help/sequence_similarities' target='_top'>More...</a></p>Sequence similaritiesi

Belongs to the oligopeptide OPT transporter family.ARBA annotation

Keywords - Domaini

Transmembrane, Transmembrane helixSequence analysisARBA annotation

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

More...eggNOGi		KOG2262, Eukaryota

The HOGENOM Database of Homologous Genes from Fully Sequenced Organisms

More...HOGENOMi		CLU_004965_1_0_1

InParanoid: Eukaryotic Ortholog Groups

More...InParanoidi		A3LZ43

Identification of Orthologs from Complete Genome Data

More...OMAi		ANIEDFC

Database of Orthologous Groups

More...OrthoDBi		246409at2759

Family and domain databases

Integrated resource of protein families, domains and functional sites

More...InterProi		View protein in InterPro
IPR004648, Oligpept_transpt
IPR004813, OPT

Pfam protein domain database

More...Pfami		View protein in Pfam
PF03169, OPT, 1 hit

TIGRFAMs; a protein family database

More...TIGRFAMsi		TIGR00727, ISP4_OPT, 1 hit
TIGR00728, OPT_sfam, 1 hit

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence%5Flength">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequencei

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences%5Fsection">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

A3LZ43-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MSKVEKKEKL DNIVSIGSVT SHLQLEDHEV NLRAITSNPV SINEIGVSLS 
        60         70         80         90        100
NEQKHFILKR LHLDGLQSLD ELPPQVIFYL DKIEKLGNDE ALSILKETLV 
       110        120        130        140        150
EHHDDTNIPT HDLELWTKLV DIGAENSGTR VKLDSALNEK NNESGESSSQ 
       160        170        180        190        200
EVFEGGKYES SIHQVVDWDL QLRLEAVLIA YHSPYPEVRS VTDPFDDPTI 
       210        220        230        240        250
PVETIRVYIL GIVWTAIGAV IDQFFSERQP AIALYPAVVQ VFLYPCGLLL 
       260        270        280        290        300
EYVLPKYKFK IWKYTIDLNP GPWNYKEQML ASLFYSVTGG ATSYVSYNIH 
       310        320        330        340        350
VQKMKMFYDN QWVDFGYQTL LILSNNFLGF GFAGIFRRFA VYPVEAIWPT 
       360        370        380        390        400
VLPTLALNRA LMVPEKKEII NGWKIAKYTF FFIAFAASFV YFWIPNYLFG 
       410        420        430        440        450
ALSTFNWMTW IAPFNFNLVA ITGTFFGLGL NPIPSFDWNV LSLNAPLIYP 
       460        470        480        490        500
FYSQLNNYIG NILGFLAVAG VYWTNSKWSG YLPINSPSLY TNTGEIYRVT 
       510        520        530        540        550
SVVNENSLFD IEKYQEYGPP FYTAGNLVAY GSYFVLYPFS VVYEIGTRYK 
       560        570        580        590        600
QTWRAFKSLY LSFRNFKKST YEGYNDPHST MMSAYKEVPD WVFLVVLVIS 
       610        620        630        640        650
LVLAIICVEI YPAETPVWGL FFSLGINFVF LIPITAVYSR TGWGFGLNVL 
       660        670        680        690        700
VELIVGYALP GNGLALNFIK AFGTNIDSQA QNYITNQKMA HYSKVPPRAL 
       710        720        730        740        750
FRVQIIGVFI ASFVQLGIIN FLINNIEDYC DPHNKQKFTC PHSKTFYNAS 
       760        770        780        790        800
IIWGIIGPKK VFNGLYPILQ YCFLIGFLLA ILALAFKKFA PLKYTKFFEP 
       810        820        830        840        850
TLVIGGFINY GAYNLSYYTG SFYLSVVFMY YIRNKYEAWW QKYNYLLSAA 
       860        870        880        890        900
LTAGVAFSSI IIFFAVQYHD KSILWWGNSV MFGGIEGGYG QQSILNVTEA 
       910 
PGGYFGPRIG NFP
Length:913
Mass (Da):103,920
Last modified:July 24, 2007 - v2
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:iFF12676F0035F46E
GO

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...EMBLi

GenBank nucleotide sequence database

More...GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...DDBJi
Links Updated
CP000501 Genomic DNA Translation: ABN68271.2

NCBI Reference Sequences

More...RefSeqi		XP_001386300.2, XM_001386263.1

Genome annotation databases

Ensembl fungal genome annotation project

More...EnsemblFungii		ABN68271; ABN68271; PICST_63741

Database of genes from NCBI RefSeq genomes

More...GeneIDi		4840490

KEGG: Kyoto Encyclopedia of Genes and Genomes

More...KEGGi		pic:PICST_63741

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP000501 Genomic DNA Translation: ABN68271.2
RefSeqiXP_001386300.2, XM_001386263.1

3D structure databases

Database of comparative protein structure models

More...ModBasei		Search...

SWISS-MODEL Interactive Workspace

More...SWISS-MODEL-Workspacei		Submit a new modelling project...

Genome annotation databases

EnsemblFungiiABN68271; ABN68271; PICST_63741
GeneIDi4840490
KEGGipic:PICST_63741

Phylogenomic databases

eggNOGiKOG2262, Eukaryota
HOGENOMiCLU_004965_1_0_1
InParanoidiA3LZ43
OMAiANIEDFC
OrthoDBi246409at2759

Family and domain databases

InterProiView protein in InterPro
IPR004648, Oligpept_transpt
IPR004813, OPT
PfamiView protein in Pfam
PF03169, OPT, 1 hit
TIGRFAMsiTIGR00727, ISP4_OPT, 1 hit
TIGR00728, OPT_sfam, 1 hit

ProtoNet; Automatic hierarchical classification of proteins

More...ProtoNeti		Search...

MobiDB: a database of protein disorder and mobility annotations

More...MobiDBi		Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the 'Entry information' section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiA3LZ43_PICST
<p>This subsection of the 'Entry information' section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called 'Primary (citable) accession number'.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: A3LZ43
<p>This subsection of the 'Entry information' section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification ('Last modified'). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/TrEMBL: April 3, 2007
Last sequence update: July 24, 2007
Last modified: October 7, 2020
This is version 54 of the entry and version 2 of the sequence. See complete history.
<p>This subsection of the 'Entry information' section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiUnreviewed (UniProtKB/TrEMBL)

<p>This section contains any relevant information that doesn't fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Reference proteomeImported
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