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Entry version 112 (10 Feb 2021)
Sequence version 1 (03 Apr 2007)
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Protein

Protein strawberry notch homolog 1

Gene

SBNO1

Organism
Homo sapiens (Human)
Status
Reviewed-Annotation score:

Annotation score:4 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Experimental evidence at protein leveli <p>This indicates the type of evidence that supports the existence of the protein. Note that the 'protein existence' evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

GO - Biological processi

Enzyme and pathway databases

Pathway Commons web resource for biological pathway data

More...
PathwayCommonsi
A3KN83

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Recommended name:
Protein strawberry notch homolog 1
Alternative name(s):
Monocyte protein 3
Short name:
MOP-3
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: 'Name', 'Synonyms', 'Ordered locus names' and 'ORF names'.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:SBNO1
Synonyms:MOP3
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiHomo sapiens (Human)
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the 'taxonomic identifier' or 'taxid'.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri9606 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000005640 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes%5Fmanual">proteome</a> can consist of several components.<br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome 12

Organism-specific databases

Human Gene Nomenclature Database

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HGNCi
HGNC:22973, SBNO1

neXtProt; the human protein knowledge platform

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neXtProti
NX_A3KN83

Eukaryotic Pathogen, Vector and Host Database Resources

More...
VEuPathDBi
HostDB:ENSG00000139697.11

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte & Seán O’Donoghue; Source: COMPARTMENTS

<p>This section provides information on the disease(s) and phenotype(s) associated with a protein.<p><a href='/help/pathology_and_biotech_section' target='_top'>More...</a></p>Pathology & Biotechi

Organism-specific databases

DisGeNET

More...
DisGeNETi
55206

Open Targets

More...
OpenTargetsi
ENSG00000139697

The Pharmacogenetics and Pharmacogenomics Knowledge Base

More...
PharmGKBi
PA134967986

Miscellaneous databases

Pharos NIH Druggable Genome Knowledgebase

More...
Pharosi
A3KN83, Tdark

Genetic variation databases

BioMuta curated single-nucleotide variation and disease association database

More...
BioMutai
SBNO1

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'PTM / Processing' section describes the extent of a polypeptide chain in the mature protein following processing or proteolytic cleavage.<p><a href='/help/chain' target='_top'>More...</a></p>ChainiPRO_00003145551 – 1393Protein strawberry notch homolog 1Add BLAST1393

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'PTM / Processing' section specifies the position and type of each modified residue excluding <a href="http://www.uniprot.org/manual/lipid">lipids</a>, <a href="http://www.uniprot.org/manual/carbohyd">glycans</a> and <a href="http://www.uniprot.org/manual/crosslnk">protein cross-links</a>.<p><a href='/help/mod_res' target='_top'>More...</a></p>Modified residuei148PhosphoserineCombined sources1
Modified residuei149N6-acetyllysineCombined sources1
Modified residuei162PhosphoserineCombined sources1
Modified residuei214PhosphoserineCombined sources1
Modified residuei413N6-acetyllysineCombined sources1
Modified residuei692PhosphoserineBy similarity1
Modified residuei693PhosphoserineBy similarity1
Modified residuei697PhosphoserineCombined sources1
Modified residuei754PhosphoserineCombined sources1
Modified residuei755PhosphoserineCombined sources1
Modified residuei768PhosphoserineBy similarity1
Modified residuei794PhosphoserineCombined sources1
Modified residuei815PhosphoserineCombined sources1
Modified residuei1222N6-acetyllysineCombined sources1
Modified residuei1386PhosphoserineCombined sources1

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywords - PTMi

Acetylation, Phosphoprotein

Proteomic databases

Encyclopedia of Proteome Dynamics

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EPDi
A3KN83

jPOST - Japan Proteome Standard Repository/Database

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jPOSTi
A3KN83

MassIVE - Mass Spectrometry Interactive Virtual Environment

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MassIVEi
A3KN83

MaxQB - The MaxQuant DataBase

More...
MaxQBi
A3KN83

PaxDb, a database of protein abundance averages across all three domains of life

More...
PaxDbi
A3KN83

PeptideAtlas

More...
PeptideAtlasi
A3KN83

PRoteomics IDEntifications database

More...
PRIDEi
A3KN83

ProteomicsDB: a multi-organism proteome resource

More...
ProteomicsDBi
582 [A3KN83-1]
583 [A3KN83-2]
584 [A3KN83-3]
585 [A3KN83-4]

PTM databases

GlyConnect protein glycosylation platform

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GlyConnecti
2874, 1 O-Linked glycan (1 site)

GlyGen: Computational and Informatics Resources for Glycoscience

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GlyGeni
A3KN83, 2 sites, 1 O-linked glycan (2 sites)

iPTMnet integrated resource for PTMs in systems biology context

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iPTMneti
A3KN83

MetOSite database of methionine sulfoxide sites

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MetOSitei
A3KN83

Comprehensive resource for the study of protein post-translational modifications (PTMs) in human, mouse and rat.

More...
PhosphoSitePlusi
A3KN83

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

Gene expression databases

Bgee dataBase for Gene Expression Evolution

More...
Bgeei
ENSG00000139697, Expressed in testis and 233 other tissues

Genevisible search portal to normalized and curated expression data from Genevestigator

More...
Genevisiblei
A3KN83, HS

Organism-specific databases

Human Protein Atlas

More...
HPAi
ENSG00000139697, Tissue enhanced (testis)

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

GO - Molecular functioni

Protein-protein interaction databases

The Biological General Repository for Interaction Datasets (BioGRID)

More...
BioGRIDi
120502, 30 interactors

Protein interaction database and analysis system

More...
IntActi
A3KN83, 7 interactors

STRING: functional protein association networks

More...
STRINGi
9606.ENSP00000387361

Miscellaneous databases

RNAct, Protein-RNA interaction predictions for model organisms.

More...
RNActi
A3KN83, protein

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

3D structure databases

SWISS-MODEL Repository - a database of annotated 3D protein structure models

More...
SMRi
A3KN83

Database of comparative protein structure models

More...
ModBasei
Search...

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Coiled coil

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Family and domains' section denotes the positions of regions of coiled coil within the protein.<p><a href='/help/coiled' target='_top'>More...</a></p>Coiled coili843 – 870Sequence analysisAdd BLAST28

Compositional bias

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Family and Domains' section describes the position of regions of compositional bias within the protein and the particular amino acids that are over-represented within those regions.<p><a href='/help/compbias' target='_top'>More...</a></p>Compositional biasi784 – 793Poly-Lys10

<p>This subsection of the 'Family and domains' section provides information about the sequence similarity with other proteins.<p><a href='/help/sequence_similarities' target='_top'>More...</a></p>Sequence similaritiesi

Belongs to the SBNO family.Curated

Keywords - Domaini

Coiled coil

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

More...
eggNOGi
KOG1513, Eukaryota

Ensembl GeneTree

More...
GeneTreei
ENSGT00940000155449

The HOGENOM Database of Homologous Genes from Fully Sequenced Organisms

More...
HOGENOMi
CLU_000212_2_2_1

InParanoid: Eukaryotic Ortholog Groups

More...
InParanoidi
A3KN83

Identification of Orthologs from Complete Genome Data

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OMAi
GQFWAAH

Database of Orthologous Groups

More...
OrthoDBi
141580at2759

Database for complete collections of gene phylogenies

More...
PhylomeDBi
A3KN83

TreeFam database of animal gene trees

More...
TreeFami
TF313526

Family and domain databases

Integrated resource of protein families, domains and functional sites

More...
InterProi
View protein in InterPro
IPR027417, P-loop_NTPase
IPR026937, SBNO_Helicase_C_dom
IPR026741, SNO
IPR039187, SNO_AAA

The PANTHER Classification System

More...
PANTHERi
PTHR12706, PTHR12706, 1 hit

Pfam protein domain database

More...
Pfami
View protein in Pfam
PF13872, AAA_34, 1 hit
PF13871, Helicase_C_4, 1 hit

Superfamily database of structural and functional annotation

More...
SUPFAMi
SSF52540, SSF52540, 2 hits

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence%5Flength">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequences (4)i

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences%5Fsection">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

This entry describes 4 <p>This subsection of the 'Sequence' section lists the alternative protein sequences (isoforms) that can be generated from the same gene by a single or by the combination of up to four biological events (alternative promoter usage, alternative splicing, alternative initiation and ribosomal frameshifting). Additionally, this section gives relevant information on each alternative protein isoform. This section is only present in reviewed entries, i.e. in UniProtKB/Swiss-Prot.<p><a href='/help/alternative_products' target='_top'>More...</a></p> isoformsi produced by alternative splicing. AlignAdd to basket
Isoform 1 (identifier: A3KN83-1) [UniParc]FASTAAdd to basket

This isoform has been chosen as the <div> <p><b>What is the canonical sequence?</b><p><a href='/help/canonical_and_isoforms' target='_top'>More...</a></p>canonicali sequence. All positional information in this entry refers to it. This is also the sequence that appears in the downloadable versions of the entry.

« Hide
        10         20         30         40         50
MVEPGQDLLL AALSESGISP NDLFDIDGGD AGLATPMPTP SVQQSVPLSA
60 70 80 90 100
LELGLETEAA VPVKQEPETV PTPALLNVRQ QPPSTTTFVL NQINHLPPLG
110 120 130 140 150
STIVMTKTPP VTTNRQTITL TKFIQTTAST RPSVSAPTVR NAMTSAPSKD
160 170 180 190 200
QVQLKDLLKN NSLNELMKLK PPANIAQPVA TAATDVSNGT VKKESSNKEG
210 220 230 240 250
ARMWINDMKM RSFSPTMKVP VVKEDDEPEE EDEEEMGHAE TYAEYMPIKL
260 270 280 290 300
KIGLRHPDAV VETSSLSSVT PPDVWYKTSI SEETIDNGWL SALQLEAITY
310 320 330 340 350
AAQQHETFLP NGDRAGFLIG DGAGVGKGRT IAGIIYENYL LSRKRALWFS
360 370 380 390 400
VSNDLKYDAE RDLRDIGAKN ILVHSLNKFK YGKISSKHNG SVKKGVIFAT
410 420 430 440 450
YSSLIGESQS GGKYKTRLKQ LLHWCGDDFD GVIVFDECHK AKNLCPVGSS
460 470 480 490 500
KPTKTGLAVL ELQNKLPKAR VVYASATGAS EPRNMAYMNR LGIWGEGTPF
510 520 530 540 550
REFSDFIQAV ERRGVGAMEI VAMDMKLRGM YIARQLSFTG VTFKIEEVLL
560 570 580 590 600
SQSYVKMYNK AVKLWVIARE RFQQAADLID AEQRMKKSMW GQFWSAHQRF
610 620 630 640 650
FKYLCIASKV KRVVQLAREE IKNGKCVVIG LQSTGEARTL EALEEGGGEL
660 670 680 690 700
NDFVSTAKGV LQSLIEKHFP APDRKKLYSL LGIDLTAPSN NSSPRDSPCK
710 720 730 740 750
ENKIKKRKGE EITREAKKAR KVGGLTGSSS DDSGSESDAS DNEESDYESS
760 770 780 790 800
KNMSSGDDDD FNPFLDESNE DDENDPWLIR KDHKKNKEKK KKKSIDPDSI
810 820 830 840 850
QSALLASGLG SKRPSFSSTP VISPAPNSTP ANSNTNSNSS LITSQDAVER
860 870 880 890 900
AQQMKKDLLD KLEKLAEDLP PNTLDELIDE LGGPENVAEM TGRKGRVVSN
910 920 930 940 950
DDGSISYESR SELDVPVEIL NITEKQRFMD GDKNIAIISE AASSGISLQA
960 970 980 990 1000
DRRAKNQRRR VHMTLELPWS ADRAIQQFGR THRSNQVTAP EYVFLISELA
1010 1020 1030 1040 1050
GEQRFASIVA KRLESLGALT HGDRRATESR DLSRFNFDNK YGRNALEIVM
1060 1070 1080 1090 1100
KSIVNLDSPM VSPPPDYPGE FFKDVRQGLI GVGLINVEDR SGILTLDKDY
1110 1120 1130 1140 1150
NNIGKFLNRI LGMEVHQQNA LFQYFADTLT AVVQNAKKNG RYDMGILDLG
1160 1170 1180 1190 1200
SGDEKVRKSD VKKFLTPGYS TSGHVELYTI SVERGMSWEE ATKIWAELTG
1210 1220 1230 1240 1250
PDDGFYLSLQ IRNNKKTAIL VKEVNPKKKL FLVYRPNTGK QLKLEIYADL
1260 1270 1280 1290 1300
KKKYKKVVSD DALMHWLDQY NSSADTCTHA YWRGNCKKAS LGLVCEIGLR
1310 1320 1330 1340 1350
CRTYYVLCGS VLSVWTKVEG VLASVSGTNV KMQIVRLRTE DGQRIVGLII
1360 1370 1380 1390
PANCVSPLVN LLSTSDQSQQ LAVQQKQLWQ QHHPQSITNL SNA
Length:1,393
Mass (Da):154,312
Last modified:April 3, 2007 - v1
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:iD2C42F29C7EEC20D
GO
Isoform 2 (identifier: A3KN83-2) [UniParc]FASTAAdd to basket

The sequence of this isoform differs from the canonical sequence as follows:
     80-81: QQ → Q

Show »
Length:1,392
Mass (Da):154,184
Checksum:i4CB83A00B1DBEC22
GO
Isoform 3 (identifier: A3KN83-3) [UniParc]FASTAAdd to basket

The sequence of this isoform differs from the canonical sequence as follows:
     78-79: Missing.

Show »
Length:1,391
Mass (Da):154,057
Checksum:i3682A9E4AB3A70E2
GO
Isoform 4 (identifier: A3KN83-4) [UniParc]FASTAAdd to basket

The sequence of this isoform differs from the canonical sequence as follows:
     80-81: QQ → Q
     722-733: VGGLTGSSSDDS → MSLMRMMKMIPG
     734-1393: Missing.

Show »
Length:732
Mass (Da):80,852
Checksum:i28DAA87F2379ABE5
GO

<p>This subsection of the 'Sequence' section reports difference(s) between the protein sequence shown in the UniProtKB entry and other available protein sequences derived from the same gene.<p><a href='/help/sequence_caution' target='_top'>More...</a></p>Sequence cautioni

The sequence AAQ76814 differs from that shown. Reason: Erroneous initiation.Curated

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Sequence' section reports difference(s) between the canonical sequence (displayed by default in the entry) and the different sequence submissions merged in the entry. These various submissions may originate from different sequencing projects, different types of experiments, or different biological samples. Sequence conflicts are usually of unknown origin.<p><a href='/help/conflict' target='_top'>More...</a></p>Sequence conflicti4P → Q in AAQ76814 (PubMed:16533400).Curated1
Sequence conflicti14S → R in BAA91842 (PubMed:14702039).Curated1
Sequence conflicti555V → A in AAQ76814 (PubMed:16533400).Curated1
Sequence conflicti774N → S in BAB19784 (Ref. 1) Curated1

Natural variant

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Sequence' section describes natural variant(s) of the protein sequence.<p><a href='/help/variant' target='_top'>More...</a></p>Natural variantiVAR_037910634T → S in a breast cancer sample; somatic mutation. 1 Publication1
Natural variantiVAR_037911728S → N. Corresponds to variant dbSNP:rs1060105Ensembl.1
Natural variantiVAR_057794729S → N. Corresponds to variant dbSNP:rs1060105Ensembl.1
Natural variantiVAR_037912889E → K in a breast cancer sample; somatic mutation. 1 Publication1
Natural variantiVAR_037913997S → C in a breast cancer sample; somatic mutation. 1 Publication1

Alternative sequence

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Sequence' section describes the sequence of naturally occurring alternative protein isoform(s). The changes in the amino acid sequence may be due to alternative splicing, alternative promoter usage, alternative initiation, or ribosomal frameshifting.<p><a href='/help/var_seq' target='_top'>More...</a></p>Alternative sequenceiVSP_03029578 – 79Missing in isoform 3. 1 Publication2
Alternative sequenceiVSP_03029680 – 81QQ → Q in isoform 2 and isoform 4. 3 Publications2
Alternative sequenceiVSP_030297722 – 733VGGLT…SSDDS → MSLMRMMKMIPG in isoform 4. 1 PublicationAdd BLAST12
Alternative sequenceiVSP_030298734 – 1393Missing in isoform 4. 1 PublicationAdd BLAST660

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...
EMBLi

GenBank nucleotide sequence database

More...
GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...
DDBJi
Links Updated
AB014772 mRNA Translation: BAB19784.1
BC030544 mRNA Translation: AAH30544.1
BC133704 mRNA Translation: AAI33705.1
AK001695 mRNA Translation: BAA91842.1
AY364255 mRNA Translation: AAQ76814.1 Different initiation.

The Consensus CDS (CCDS) project

More...
CCDSi
CCDS53844.1 [A3KN83-1]
CCDS9246.1 [A3KN83-2]

NCBI Reference Sequences

More...
RefSeqi
NP_001161328.1, NM_001167856.2 [A3KN83-1]
NP_060653.3, NM_018183.4 [A3KN83-2]
XP_005253630.1, XM_005253573.4
XP_005253633.1, XM_005253576.3
XP_006719536.1, XM_006719473.3
XP_006719537.1, XM_006719474.3
XP_011536835.1, XM_011538533.2
XP_016875045.1, XM_017019556.1

Genome annotation databases

Ensembl eukaryotic genome annotation project

More...
Ensembli
ENST00000267176; ENSP00000267176; ENSG00000139697 [A3KN83-2]
ENST00000420886; ENSP00000387361; ENSG00000139697 [A3KN83-1]
ENST00000602398; ENSP00000473665; ENSG00000139697 [A3KN83-1]

Database of genes from NCBI RefSeq genomes

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GeneIDi
55206

KEGG: Kyoto Encyclopedia of Genes and Genomes

More...
KEGGi
hsa:55206

UCSC genome browser

More...
UCSCi
uc010tao.3, human [A3KN83-1]

Keywords - Coding sequence diversityi

Alternative splicing

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AB014772 mRNA Translation: BAB19784.1
BC030544 mRNA Translation: AAH30544.1
BC133704 mRNA Translation: AAI33705.1
AK001695 mRNA Translation: BAA91842.1
AY364255 mRNA Translation: AAQ76814.1 Different initiation.
CCDSiCCDS53844.1 [A3KN83-1]
CCDS9246.1 [A3KN83-2]
RefSeqiNP_001161328.1, NM_001167856.2 [A3KN83-1]
NP_060653.3, NM_018183.4 [A3KN83-2]
XP_005253630.1, XM_005253573.4
XP_005253633.1, XM_005253576.3
XP_006719536.1, XM_006719473.3
XP_006719537.1, XM_006719474.3
XP_011536835.1, XM_011538533.2
XP_016875045.1, XM_017019556.1

3D structure databases

SMRiA3KN83
ModBaseiSearch...

Protein-protein interaction databases

BioGRIDi120502, 30 interactors
IntActiA3KN83, 7 interactors
STRINGi9606.ENSP00000387361

PTM databases

GlyConnecti2874, 1 O-Linked glycan (1 site)
GlyGeniA3KN83, 2 sites, 1 O-linked glycan (2 sites)
iPTMnetiA3KN83
MetOSiteiA3KN83
PhosphoSitePlusiA3KN83

Genetic variation databases

BioMutaiSBNO1

Proteomic databases

EPDiA3KN83
jPOSTiA3KN83
MassIVEiA3KN83
MaxQBiA3KN83
PaxDbiA3KN83
PeptideAtlasiA3KN83
PRIDEiA3KN83
ProteomicsDBi582 [A3KN83-1]
583 [A3KN83-2]
584 [A3KN83-3]
585 [A3KN83-4]

Protocols and materials databases

Antibodypedia a portal for validated antibodies

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Antibodypediai
52514, 22 antibodies

Genome annotation databases

EnsembliENST00000267176; ENSP00000267176; ENSG00000139697 [A3KN83-2]
ENST00000420886; ENSP00000387361; ENSG00000139697 [A3KN83-1]
ENST00000602398; ENSP00000473665; ENSG00000139697 [A3KN83-1]
GeneIDi55206
KEGGihsa:55206
UCSCiuc010tao.3, human [A3KN83-1]

Organism-specific databases

Comparative Toxicogenomics Database

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CTDi
55206
DisGeNETi55206

GeneCards: human genes, protein and diseases

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GeneCardsi
SBNO1
HGNCiHGNC:22973, SBNO1
HPAiENSG00000139697, Tissue enhanced (testis)
neXtProtiNX_A3KN83
OpenTargetsiENSG00000139697
PharmGKBiPA134967986
VEuPathDBiHostDB:ENSG00000139697.11

GenAtlas: human gene database

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GenAtlasi
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Phylogenomic databases

eggNOGiKOG1513, Eukaryota
GeneTreeiENSGT00940000155449
HOGENOMiCLU_000212_2_2_1
InParanoidiA3KN83
OMAiGQFWAAH
OrthoDBi141580at2759
PhylomeDBiA3KN83
TreeFamiTF313526

Enzyme and pathway databases

PathwayCommonsiA3KN83

Miscellaneous databases

BioGRID ORCS database of CRISPR phenotype screens

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BioGRID-ORCSi
55206, 652 hits in 875 CRISPR screens

ChiTaRS: a database of human, mouse and fruit fly chimeric transcripts and RNA-sequencing data

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ChiTaRSi
SBNO1, human

Database of phenotypes from RNA interference screens in Drosophila and Homo sapiens

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GenomeRNAii
55206
PharosiA3KN83, Tdark

Protein Ontology

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PROi
PR:A3KN83
RNActiA3KN83, protein

Gene expression databases

BgeeiENSG00000139697, Expressed in testis and 233 other tissues
GenevisibleiA3KN83, HS

Family and domain databases

InterProiView protein in InterPro
IPR027417, P-loop_NTPase
IPR026937, SBNO_Helicase_C_dom
IPR026741, SNO
IPR039187, SNO_AAA
PANTHERiPTHR12706, PTHR12706, 1 hit
PfamiView protein in Pfam
PF13872, AAA_34, 1 hit
PF13871, Helicase_C_4, 1 hit
SUPFAMiSSF52540, SSF52540, 2 hits

ProtoNet; Automatic hierarchical classification of proteins

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ProtoNeti
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MobiDB: a database of protein disorder and mobility annotations

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MobiDBi
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<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the 'Entry information' section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiSBNO1_HUMAN
<p>This subsection of the 'Entry information' section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called 'Primary (citable) accession number'.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: A3KN83
Secondary accession number(s): Q05C06
, Q3ZTS3, Q9H3T8, Q9NVB2
<p>This subsection of the 'Entry information' section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification ('Last modified'). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/Swiss-Prot: January 15, 2008
Last sequence update: April 3, 2007
Last modified: February 10, 2021
This is version 112 of the entry and version 1 of the sequence. See complete history.
<p>This subsection of the 'Entry information' section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

<p>This section contains any relevant information that doesn't fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Reference proteome

Documents

  1. Human chromosome 12
    Human chromosome 12: entries, gene names and cross-references to MIM
  2. Human variants curated from literature reports
    Index of human variants curated from literature reports
  3. SIMILARITY comments
    Index of protein domains and families
  4. Human entries with genetic variants
    List of human entries with genetic variants
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