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Protein
Submitted name:

Ercc6 protein

Gene

Ercc6

Organism
Mus musculus (Mouse)
Status
Unreviewed-Annotation score: -Experimental evidence at transcript leveli

Functioni

GO - Molecular functioni

GO - Biological processi

Names & Taxonomyi

Protein namesi
Submitted name:
Ercc6 proteinImported
Gene namesi
Name:Ercc6Imported
OrganismiMus musculus (Mouse)Imported
Taxonomic identifieri10090 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaMyomorphaMuroideaMuridaeMurinaeMusMus

Organism-specific databases

MGIiMGI:1100494 Ercc6

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

PTM / Processingi

Proteomic databases

PeptideAtlasiA3KMN2

Interactioni

GO - Molecular functioni

Structurei

3D structure databases

ProteinModelPortaliA3KMN2
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini191 – 367Helicase ATP-bindingInterPro annotationAdd BLAST177
Domaini515 – 674Helicase C-terminalInterPro annotationAdd BLAST160

Phylogenomic databases

eggNOGiKOG0387 Eukaryota
ENOG410XP4Z LUCA
HOGENOMiHOG000170952
HOVERGENiHBG103861
PhylomeDBiA3KMN2

Family and domain databases

CDDicd00079 HELICc, 1 hit
Gene3Di3.40.50.10810, 1 hit
InterProiView protein in InterPro
IPR014001 Helicase_ATP-bd
IPR001650 Helicase_C
IPR027417 P-loop_NTPase
IPR038718 SNF2-like_sf
IPR000330 SNF2_N
PfamiView protein in Pfam
PF00271 Helicase_C, 1 hit
PF00176 SNF2_N, 1 hit
SMARTiView protein in SMART
SM00487 DEXDc, 1 hit
SM00490 HELICc, 1 hit
SUPFAMiSSF52540 SSF52540, 2 hits
PROSITEiView protein in PROSITE
PS51192 HELICASE_ATP_BIND_1, 1 hit
PS51194 HELICASE_CTER, 1 hit

Sequencei

Sequence statusi: Fragment.

A3KMN2-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
DKRLKKHSRK LQRRALQFQG KVGLPSGKKP LEPEVRPEAE GDTEGEESGS
60 70 80 90 100
SPTDGEEEEE QEEEEGVASL SSDDVSYELK PLRKRQKYQK KVPVQEIDDD
110 120 130 140 150
FFPSSEEEDE AMEGRGGGRK VARRQDDGDE DYYKQRLRRW NRLRLQDKEK
160 170 180 190 200
RLKLEDDSEE SDAEFDEGFK VPGFLFKKLF KYQQTGVRWL WELHCQQAGG
210 220 230 240 250
ILGDEMGLGK TIQIIAFLAG LSYSKIRTRG SNYRFEGLGP TIIVCPTTVM
260 270 280 290 300
HQWVKEFHTW WPPFRVAVLH ETGSYTHKKE RLIRDIVYCH GVLITSYSYI
310 320 330 340 350
RLMQDDISRH DWHYVILDEG HKIRNPNAAV TLACKQFRTP HRIILSGSPM
360 370 380 390 400
QNNLRELWSL FDFIFPGKLG TLPVFMEQFS VPITMGGYSN ASPVQVKTAY
410 420 430 440 450
KCACVLRDTI NPYLLRRMKS DVKMSLSLPD KNEQVLFCRL TDEQHKVYQN
460 470 480 490 500
FIDSKAVYRI LNGENQIFSG LVALRKICNH PDLFSGGPKN ASGPPEDELE
510 520 530 540 550
EEQFGHWRRS GKMIVVESLL KIWHRQGQRV LLFSQSRQML HILEVFLRAH
560 570 580 590 600
KYSYLKMDGT TTIASRQPLI TKYNEDTSIF VFLLTTRVGG LGVNLTGANR
610 620 630 640 650
VIIYDPDWNP STDTQARERA WRIGQKKQVT VYRLLTAGTI EEKIYHRQIF
660 670 680 690 700
KQFLTNRVLK DPKQRRFFKS NDLYELFTLT SPDASQGTET SAIFAGTGSS
710 720 730 740 750
IQTPKCQLKK RTSTVLGTDP KCKKPPVSDT PANAATLIGE KPKAAGATGR
760 770 780 790 800
SVTSGESGPF KGDHDTNGNR ASSVAFGEET DAGSTLEHLS VMSGDGKHSD
810 820 830 840 850
SPTVDHTSRP PVEASTSEKQ GSSYAGARCQ AQTEPVPMSE QMEGQFSKYK
860 870 880 890 900
SKRKHDASEE ETTEKRPQPK QKAKNSKHCR DAKFEGTRVP HLVKKRRYRQ
910 920 930 940 950
QTSEQEGGAK DRSSDDYVLE KLFKKSVGVH SVVRHDAIID GSSPDYVLVE
960 970 980 990 1000
AEANRVAQDA LKALRLSRQQ CLGAASGVPT WTGHRGISGA PTGVKNRFGQ
1010 1020 1030 1040 1050
KRDSSLPVQH PSSLTEKTQN NMKKEGKAHT PEHFSGKEDG ASVSGAPSSS
1060 1070 1080 1090 1100
SLLARMRARN HMILPERLES DSEHLAEAAA VPPCGTEHDD LLVDMRNFIA
1110 1120 1130 1140 1150
FQAQVDGQAS TQEILQEFES KLSVAQSCVF RELLRNLCNF HRTPGGEGIW

KLKPEYC
Length:1,157
Mass (Da):130,477
Last modified:April 3, 2007 - v1
Checksum:i412E5314493B29F3
GO

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Non-terminal residuei1Imported1

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BC132447 mRNA Translation: AAI32448.1
UniGeneiMm.318310

Similar proteinsi

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BC132447 mRNA Translation: AAI32448.1
UniGeneiMm.318310

3D structure databases

ProteinModelPortaliA3KMN2
ModBaseiSearch...
MobiDBiSearch...

Proteomic databases

PeptideAtlasiA3KMN2

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Organism-specific databases

MGIiMGI:1100494 Ercc6

Phylogenomic databases

eggNOGiKOG0387 Eukaryota
ENOG410XP4Z LUCA
HOGENOMiHOG000170952
HOVERGENiHBG103861
PhylomeDBiA3KMN2

Miscellaneous databases

SOURCEiSearch...

Family and domain databases

CDDicd00079 HELICc, 1 hit
Gene3Di3.40.50.10810, 1 hit
InterProiView protein in InterPro
IPR014001 Helicase_ATP-bd
IPR001650 Helicase_C
IPR027417 P-loop_NTPase
IPR038718 SNF2-like_sf
IPR000330 SNF2_N
PfamiView protein in Pfam
PF00271 Helicase_C, 1 hit
PF00176 SNF2_N, 1 hit
SMARTiView protein in SMART
SM00487 DEXDc, 1 hit
SM00490 HELICc, 1 hit
SUPFAMiSSF52540 SSF52540, 2 hits
PROSITEiView protein in PROSITE
PS51192 HELICASE_ATP_BIND_1, 1 hit
PS51194 HELICASE_CTER, 1 hit
ProtoNetiSearch...

Entry informationi

Entry nameiA3KMN2_MOUSE
AccessioniPrimary (citable) accession number: A3KMN2
Entry historyiIntegrated into UniProtKB/TrEMBL: April 3, 2007
Last sequence update: April 3, 2007
Last modified: May 23, 2018
This is version 74 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health

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